Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13828782 | . | T | A | CCDS8662.1:NM_000834.3:c.1022aAt>aTt_NP_000825.2:p.341N>I | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | ASN | B:341 | B:341 | 102.0 | 0.637 | S | -87.6 | 87.1 | 102.0 | 0.637 | 0.0 |
NAG |
1.441 |
ND2 |
C1 |
||
ASN | D:341 | D:341 | 104.0 | 0.65 | S | -123.5 | 98.5 | 104.0 | 0.65 | 0.0 |
NAG |
3.735 |
OD1 |
O3 |
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6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | ASN | B:372 | B:341 | 114.0 | 0.713 | S | -117.1 | 102.3 | 114.0 | 0.713 | 0.0 |
NAG NAG NAG |
4.184 6.606 1.438 |
OD1 ND2 ND2 |
N2 O5 C1 |
||
ASN | D:372 | D:341 | 113.0 | 0.706 | S | -117.1 | 102.3 | 113.0 | 0.706 | 0.0 |
NAG NAG NAG |
4.183 6.606 1.437 |
OD1 ND2 ND2 |
N2 O5 C1 |
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5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ASN | B:316 | B:341 | 70.0 | NA | S | -112.9 | 106.5 | 70.0 | NA | NA | ||||||
ASN | D:316 | D:341 | 70.0 | NA | S | -112.9 | 106.5 | 70.0 | NA | NA | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ASN | B:316 | B:341 | 86.0 | NA | S | -94.6 | 120.2 | 86.0 | NA | NA | ||||||
ASN | D:316 | D:341 | 86.0 | NA | S | -94.6 | 120.2 | 86.0 | NA | NA | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ASN | B:316 | B:341 | 86.0 | NA | S | -83.4 | 120.9 | 86.0 | NA | NA | ||||||
ASN | D:316 | D:341 | 84.0 | NA | S | -83.4 | 120.9 | 84.0 | NA | NA | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | ASN | B:316 | B:341 | 82.0 | NA | -92.1 | 107.7 | 82.0 | NA | NA | |||||||
ASN | D:316 | D:341 | 81.0 | NA | -92.2 | 107.8 | 81.0 | NA | NA | ||||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ASN | B:316 | B:341 | 86.0 | NA | S | -69.8 | 123.7 | 86.0 | NA | NA | ||||||
ASN | D:316 | D:341 | 89.0 | NA | S | -69.8 | 123.7 | 89.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ASN | B:372 | B:341 | 88.0 | 0.55 | E | -140.6 | 135.3 | 88.0 | 0.55 | 0.0 |
NAG |
1.441 |
ND2 |
C1 |
||
ASN | D:372 | D:341 | 87.0 | 0.544 | E | -140.6 | 135.3 | 87.0 | 0.544 | 0.0 |
NAG |
1.440 |
ND2 |
C1 |
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6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ASN | B:372 | B:341 | 125.0 | 0.781 | S | -119.9 | 83.1 | 125.0 | 0.781 | 0.0 |
NAG |
1.439 |
ND2 |
C1 |
||
ASN | D:372 | D:341 | 125.0 | 0.781 | S | -119.8 | 83.1 | 125.0 | 0.781 | 0.0 |
NAG |
1.439 |
ND2 |
C1 |
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6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ASN | B:372 | B:341 | 133.0 | 0.831 | S | -99.9 | 98.9 | 133.0 | 0.831 | 0.0 | ||||||
ASN | D:372 | D:341 | 133.0 | 0.831 | S | -99.9 | 99.0 | 133.0 | 0.831 | 0.0 | |||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ASN | B:372 | B:341 | 91.0 | 0.569 | S | -103.9 | 15.0 | 91.0 | 0.569 | 0.0 | ||||||
ASN | D:372 | D:341 | 92.0 | 0.575 | S | -103.8 | 15.0 | 92.0 | 0.575 | 0.0 | |||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ASN | B:372 | B:341 | 97.0 | 0.606 | S | -99.2 | 90.2 | 97.0 | 0.606 | 0.0 |
NAG NAG |
1.435 6.717 |
ND2 ND2 |
C1 C1 |
||
ASN | D:372 | D:341 | 132.0 | 0.825 | S | -72.9 | 66.5 | 132.0 | 0.825 | 0.0 | |||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | ASN | B:372 | B:341 | 117.0 | 0.731 | -125.2 | 106.9 | 117.0 | 0.731 | 0.0 | |||||||
ASN | D:372 | D:341 | 115.0 | 0.719 | -125.2 | 106.9 | 115.0 | 0.719 | 0.0 | ||||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | ASN | B:372 | B:341 | 106.0 | 0.662 | S | -128.5 | 96.2 | 106.0 | 0.662 | 0.0 | ||||||
ASN | D:372 | D:341 | 138.0 | 0.863 | S | -117.9 | 83.7 | 138.0 | 0.863 | 0.0 | |||||||||||||
6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | ASN | B:372 | B:341 | 113.0 | 0.706 | S | -111.7 | 84.3 | 113.0 | 0.706 | 0.0 | ||||||
ASN | D:372 | D:341 | 112.0 | 0.7 | S | -111.7 | 84.3 | 112.0 | 0.7 | 0.0 | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | ASN | B:372 | B:341 | 117.0 | 0.731 | -147.0 | 97.2 | 117.0 | 0.731 | 0.0 |
NAG |
2.279 |
ND2 |
O3 |
|||
ASN | D:372 | D:341 | 115.0 | 0.719 | -147.0 | 97.3 | 115.0 | 0.719 | 0.0 |
NAG |
2.279 |
ND2 |
O3 |
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4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | ASN | B:315 | B:341 | 106.0 | 0.662 | -142.0 | 76.3 | 106.0 | 0.662 | 0.0 |
NAG |
1.440 |
ND2 |
C1 |
|||
ASN | D:315 | D:341 | 113.0 | 0.706 | -144.3 | 68.4 | 113.0 | 0.706 | 0.0 |
NAG |
1.439 |
ND2 |
C1 |
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6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | ASN | B:308 | B:341 | 104.0 | 0.65 | -101.9 | 116.6 | 104.0 | 0.65 | 0.0 |
NAG |
1.454 |
ND2 |
C1 |
|||
ASN | D:308 | D:341 | 104.0 | 0.65 | -101.9 | 116.6 | 104.0 | 0.65 | 0.0 |
NAG |
1.453 |
ND2 |
C1 |
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5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | ASN | D:336 | D:336 | 110.0 | 0.688 | S | -87.0 | 73.7 | 110.0 | 0.688 | 0.0 |
NAG NAG |
1.547 6.537 |
ND2 ND2 |
C1 C1 |
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5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | ASN | D:336 | D:336 | 107.0 | 0.669 | S | -86.6 | 74.7 | 107.0 | 0.669 | 0.0 |
NAG NAG |
1.493 6.484 |
ND2 ND2 |
C1 C1 |
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5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | C:336 | B:336 | 89.0 | NA | S | -112.1 | 94.2 | 89.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 90.0 | NA | S | -112.5 | 94.2 | 90.0 | NA | NA | |||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | C:336 | B:336 | 88.0 | NA | S | -113.7 | 95.6 | 88.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 90.0 | NA | S | -112.0 | 93.6 | 90.0 | NA | NA | |||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | B:336 | B:336 | 57.0 | NA | S | -109.2 | 120.0 | 57.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 60.0 | NA | S | -105.8 | 120.6 | 60.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | B:336 | B:336 | 55.0 | NA | S | -109.3 | 120.0 | 55.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 60.0 | NA | S | -105.8 | 120.6 | 60.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | B:336 | B:336 | 57.0 | NA | S | -109.2 | 120.0 | 57.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 60.0 | NA | S | -105.9 | 120.6 | 60.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | B:336 | B:336 | 57.0 | NA | S | -109.3 | 120.0 | 57.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 61.0 | NA | S | -105.8 | 120.6 | 61.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | B:336 | B:336 | 57.0 | NA | S | -109.2 | 120.0 | 57.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 59.0 | NA | S | -105.8 | 120.6 | 59.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASN | B:336 | B:336 | 61.0 | NA | S | -105.8 | 120.7 | 61.0 | NA | NA | ||||||
ASN | D:336 | D:336 | 58.0 | NA | S | -105.7 | 120.6 | 58.0 | NA | NA | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | ASN | B:317 | B:336 | 105.0 | 0.656 | -106.6 | 113.3 | 105.0 | 0.656 | 0.0 |
NAG |
1.447 |
ND2 |
C1 |
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ASN | D:317 | D:336 | 122.0 | 0.762 | -99.8 | 112.9 | 122.0 | 0.762 | 0.0 | ||||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | ASN | B:317 | B:336 | 116.0 | 0.725 | S | -109.3 | 120.0 | 116.0 | 0.725 | 0.0 |
NAG |
2.832 |
ND2 |
C1 |
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ASN | D:317 | D:336 | 67.0 | NA | S | -105.8 | 120.7 | 67.0 | NA | NA | |||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ASN | B:311 | B:341 | 118.0 | 0.738 | S | -125.8 | 45.3 | 118.0 | 0.738 | 0.0 |
NAG HOH |
1.432 7.167 |
ND2 OD1 |
C1 O |
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ASN | D:311 | D:341 | 111.0 | 0.694 | S | -135.7 | 22.7 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ASN | B:311 | B:341 | 105.0 | 0.656 | S | -149.9 | 62.1 | 105.0 | 0.656 | 0.0 |
NAG HOH |
1.433 7.176 |
ND2 ND2 |
C1 O |
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ASN | D:311 | D:341 | 115.0 | 0.719 | S | -116.0 | 4.8 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ASN | B:311 | B:341 | 116.0 | 0.725 | S | -133.6 | 40.0 | 116.0 | 0.725 | 0.0 |
NAG HOH |
1.432 3.289 |
ND2 N |
C1 O |
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ASN | D:311 | D:341 | 112.0 | 0.7 | S | -135.9 | 11.7 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | ASN | B:311 | B:341 | 110.0 | 0.688 | -144.0 | 67.8 | 110.0 | 0.688 | 0.0 |
NAG HOH |
1.441 8.627 |
ND2 OD1 |
C1 O |
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ASN | D:311 | D:341 | 113.0 | 0.706 | S | -118.2 | 23.8 | 113.0 | 0.706 | 0.0 |
NAG |
1.440 |
ND2 |
C1 |
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3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | ASN | B:311 | B:341 | 117.0 | 0.731 | S | -82.4 | 85.0 | 117.0 | 0.731 | 0.0 |
NAG |
1.440 |
ND2 |
C1 |
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ASN | D:311 | D:341 | 125.0 | 0.781 | S | -119.7 | 4.3 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | ASN | C:311 | C:341 | 102.0 | 0.637 | S | -139.6 | 50.0 | 102.0 | 0.637 | 0.0 |
HOH |
3.133 |
O |
O |
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ASN | E:311 | D:341 | 112.0 | 0.7 | S | -139.3 | 49.3 | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | ASN | A:310 | A:341 | 115.0 | 0.719 | T | -129.0 | 18.6 | 115.0 | 0.719 | 0.0 |
NAG HOH |
1.441 3.560 |
ND2 N |
C1 O |
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3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | ASN | A:310 | A:341 | 114.0 | 0.713 | T | -145.0 | 18.3 | 114.0 | 0.713 | 0.0 |
NAG |
1.450 |
ND2 |
C1 |
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6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 110.0 | 0.688 | S | -134.1 | 36.9 | 110.0 | 0.688 | 0.0 |
NAG HOH |
1.447 2.720 |
ND2 OD1 |
C1 O |
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ASN | D:310 | D:341 | 115.0 | 0.719 | S | -129.5 | 24.3 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 111.0 | 0.694 | S | -141.1 | 37.5 | 111.0 | 0.694 | 0.0 |
NAG HOH |
1.439 2.606 |
ND2 OD1 |
C1 O |
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ASN | D:310 | D:341 | 111.0 | 0.694 | S | -138.3 | 30.1 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 122.0 | 0.762 | S | -128.1 | 55.8 | 122.0 | 0.762 | 0.0 |
NAG HOH |
1.441 2.544 |
ND2 OD1 |
C1 O |
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ASN | D:310 | D:341 | 122.0 | 0.762 | S | -132.0 | 50.4 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 115.0 | 0.719 | S | -129.0 | 48.3 | 115.0 | 0.719 | 0.0 |
NAG HOH |
1.445 2.748 |
ND2 OD1 |
C1 O |
||
ASN | D:310 | D:341 | 119.0 | 0.744 | S | -125.7 | 34.5 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 113.0 | 0.706 | S | -133.0 | 41.3 | 113.0 | 0.706 | 0.0 |
HOH |
2.644 |
OD1 |
O |
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ASN | D:310 | D:341 | 119.0 | 0.744 | S | -129.7 | 33.4 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 107.0 | 0.669 | T | -144.9 | 37.1 | 107.0 | 0.669 | 0.0 |
NAG HOH |
1.438 3.061 |
ND2 OD1 |
C1 O |
||
ASN | D:310 | D:341 | 112.0 | 0.7 | S | -143.5 | 31.2 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ASN | B:310 | B:341 | 109.0 | 0.681 | S | -136.3 | 40.6 | 109.0 | 0.681 | 0.0 |
NAG HOH |
1.441 2.763 |
ND2 OD1 |
C1 O |
||
ASN | D:310 | D:341 | 112.0 | 0.7 | S | -132.2 | 29.2 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | ASN | B:310 | D:341 | 120.0 | 0.75 | S | -139.7 | 77.6 | 120.0 | 0.75 | 0.0 |
NAG HOH |
1.451 9.691 |
ND2 CB |
C1 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | ASN | A:341 | A:341 | 113.0 | 0.706 | S | -118.6 | 80.9 |