Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13906449 | . | G | A | CCDS8662.1:NM_000834.3:c.812gCg>gTg_NP_000825.2:p.271A>V | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | ALA | B:271 | B:271 | 103.0 | 0.896 | T | -64.6 | -39.2 | 103.0 | 0.896 | 0.0 | ||||||
ALA | D:271 | D:271 | 105.0 | 0.913 | T | -75.7 | -10.5 | 105.0 | 0.913 | 0.0 | |||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | SER | B:302 | B:271 | 71.0 | 0.617 | S | -76.5 | -176.5 | 71.0 | 0.617 | 0.0 | ||||||
SER | D:302 | D:271 | 71.0 | 0.617 | S | -76.5 | -176.5 | 71.0 | 0.617 | 0.0 | |||||||||||||
5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | SER | B:246 | B:271 | 100.0 | NA | T | -72.8 | -20.8 | 100.0 | NA | NA | ||||||
SER | D:246 | D:271 | 103.0 | NA | T | -72.8 | -20.8 | 103.0 | NA | NA | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | SER | B:246 | B:271 | 108.0 | NA | T | -64.8 | -35.4 | 108.0 | NA | NA | ||||||
SER | D:246 | D:271 | 112.0 | NA | T | -64.7 | -35.4 | 112.0 | NA | NA | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | SER | B:246 | B:271 | 107.0 | NA | S | -69.7 | -15.4 | 107.0 | NA | NA | ||||||
SER | D:246 | D:271 | 109.0 | NA | S | -69.6 | -15.4 | 109.0 | NA | NA | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | SER | B:246 | B:271 | 99.0 | NA | S | -71.3 | -53.1 | 99.0 | NA | NA | ||||||
SER | D:246 | D:271 | 103.0 | NA | S | -71.3 | -53.1 | 103.0 | NA | NA | |||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | SER | B:246 | B:271 | 113.0 | NA | T | -63.8 | -14.7 | 113.0 | NA | NA | ||||||
SER | D:246 | D:271 | 113.0 | NA | T | -63.8 | -14.7 | 113.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | SER | B:302 | B:271 | 102.0 | 0.887 | T | -56.2 | -36.7 | 102.0 | 0.887 | 0.0 | ||||||
SER | D:302 | D:271 | 102.0 | 0.887 | T | -56.2 | -36.7 | 102.0 | 0.887 | 0.0 | |||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | SER | B:302 | B:271 | 100.0 | 0.87 | T | -72.8 | -13.3 | 100.0 | 0.87 | 0.0 | ||||||
SER | D:302 | D:271 | 96.0 | 0.835 | T | -72.8 | -13.4 | 96.0 | 0.835 | 0.0 | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | SER | B:302 | B:271 | 112.0 | 0.974 | T | -78.1 | -12.4 | 112.0 | 0.974 | 0.0 | ||||||
SER | D:302 | D:271 | 111.0 | 0.965 | T | -78.1 | -12.5 | 111.0 | 0.965 | 0.0 | |||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | SER | B:302 | B:271 | 96.0 | 0.835 | S | -75.1 | -54.7 | 96.0 | 0.835 | 0.0 | ||||||
SER | D:302 | D:271 | 96.0 | 0.835 | S | -75.0 | -54.6 | 96.0 | 0.835 | 0.0 | |||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | SER | B:302 | B:271 | 97.0 | 0.843 | T | -66.1 | -14.0 | 97.0 | 0.843 | 0.0 | ||||||
SER | D:302 | D:271 | 117.0 | 1.0 | S | -64.8 | -15.0 | 117.0 | 1.0 | 0.0 | |||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | SER | B:302 | B:271 | 100.0 | 0.87 | S | -86.1 | -16.3 | 100.0 | 0.87 | 0.0 | ||||||
SER | D:302 | D:271 | 102.0 | 0.887 | S | -86.2 | -16.3 | 102.0 | 0.887 | 0.0 | |||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | SER | B:302 | B:271 | 65.0 | 0.565 | S | -97.3 | 171.7 | 65.0 | 0.565 | 0.0 | ||||||
SER | D:302 | D:271 | 126.0 | 1.0 | T | -53.0 | -25.9 | 126.0 | 1.0 | 0.0 | |||||||||||||
6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | SER | B:302 | B:271 | 111.0 | 0.965 | T | -72.3 | -15.9 | 111.0 | 0.965 | 0.0 | ||||||
SER | D:302 | D:271 | 112.0 | 0.974 | T | -72.2 | -15.9 | 112.0 | 0.974 | 0.0 | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | SER | B:302 | B:271 | 80.0 | 0.696 | T | -68.7 | -59.2 | 80.0 | 0.696 | 0.0 | ||||||
SER | D:302 | D:271 | 78.0 | 0.678 | T | -68.6 | -59.2 | 78.0 | 0.678 | 0.0 | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | SER | B:245 | B:271 | 108.0 | 0.939 | T | -68.6 | -24.2 | 108.0 | 0.939 | 0.0 | ||||||
SER | D:245 | D:271 | 91.0 | 0.791 | T | -68.9 | -24.1 | 91.0 | 0.791 | 0.0 | |||||||||||||
6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | SER | B:238 | B:271 | 93.0 | 0.809 | T | -59.7 | -39.2 | 93.0 | 0.809 | 0.0 | ||||||
SER | D:238 | D:271 | 94.0 | 0.817 | T | -59.6 | -39.3 | 94.0 | 0.817 | 0.0 | |||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | ASP | D:266 | D:266 | 104.0 | 0.693 | T | -82.6 | 4.7 | 104.0 | 0.693 | 0.0 | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | ASP | D:266 | D:266 | 106.0 | 0.707 | T | -82.5 | 4.6 | 106.0 | 0.707 | 0.0 | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | C:266 | B:266 | 101.0 | NA | S | -104.4 | -28.4 | 101.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 99.0 | NA | S | -103.4 | -28.6 | 99.0 | NA | NA | |||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | C:266 | B:266 | 94.0 | NA | S | -156.9 | -29.7 | 94.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 101.0 | NA | S | -99.8 | -29.6 | 101.0 | NA | NA | |||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | B:266 | B:266 | 78.0 | NA | T | -82.7 | 4.7 | 78.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 78.0 | NA | T | -82.6 | 4.7 | 78.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | B:266 | B:266 | 76.0 | NA | T | -82.7 | 4.7 | 76.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 76.0 | NA | T | -82.6 | 4.7 | 76.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | B:266 | B:266 | 78.0 | NA | T | -82.6 | 4.6 | 78.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 78.0 | NA | T | -82.6 | 4.6 | 78.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | B:266 | B:266 | 74.0 | NA | T | -82.7 | 4.6 | 74.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 77.0 | NA | T | -82.6 | 4.6 | 77.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | B:266 | B:266 | 77.0 | NA | T | -82.7 | 4.7 | 77.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 75.0 | NA | T | -82.6 | 4.6 | 75.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ASP | B:266 | B:266 | 77.0 | NA | T | -82.6 | 4.6 | 77.0 | NA | NA | ||||||
ASP | D:266 | D:266 | 75.0 | NA | T | -82.6 | 4.8 | 75.0 | NA | NA | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | ASP | B:247 | B:266 | 138.0 | 0.92 | T | -74.2 | -16.6 | 138.0 | 0.92 | 0.0 | ||||||
ASP | D:247 | D:266 | 97.0 | NA | T | -73.4 | -14.6 | 97.0 | NA | NA | |||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | ASP | B:247 | B:266 | 108.0 | 0.72 | T | -82.7 | 4.7 | 108.0 | 0.72 | 0.0 | ||||||
ASP | D:247 | D:266 | 110.0 | 0.733 | T | -82.5 | 4.7 | 110.0 | 0.733 | 0.0 | |||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ALA | B:241 | B:271 | 78.0 | 0.678 | T | -51.5 | -32.3 | 78.0 | 0.678 | 0.0 |
HOH |
3.110 |
N |
O |
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ALA | D:241 | D:271 | 78.0 | 0.678 | T | -50.9 | -32.7 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ALA | B:241 | B:271 | 80.0 | 0.696 | T | -55.7 | -33.1 | 80.0 | 0.696 | 0.0 |
HOH |
2.790 |
N |
O |
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ALA | D:241 | D:271 | 81.0 | 0.704 | T | -56.3 | -32.4 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ALA | B:241 | B:271 | 81.0 | 0.704 | T | -48.3 | -34.2 | 81.0 | 0.704 | 0.0 |
HOH |
8.337 |
N |
O |
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ALA | D:241 | D:271 | 82.0 | 0.713 | T | -48.9 | -34.4 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | SER | B:241 | B:271 | 94.0 | 0.817 | T | -68.9 | -23.7 | 94.0 | 0.817 | 0.0 |
HOH |
3.336 |
N |
O |
||
SER | D:241 | D:271 | 97.0 | 0.843 | T | -61.6 | -22.2 | 97.0 | 0.843 | 0.0 |
HOH |
8.296 |
N |
O |
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3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | SER | B:241 | B:271 | 96.0 | 0.835 | T | -62.6 | -23.5 | 96.0 | 0.835 | 0.0 | ||||||
SER | D:241 | D:271 | 100.0 | 0.87 | T | -48.1 | -19.7 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | SER | C:241 | C:271 | 169.0 | 1.0 | 360.0 | -57.1 | 169.0 | 1.0 | 0.0 | |||||||
SER | E:241 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | SER | A:240 | A:271 | 104.0 | 0.904 | T | -49.0 | -24.2 | 104.0 | 0.904 | 0.0 |
CL HOH |
4.745 8.314 |
O N |
CL O |
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3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | SER | A:240 | A:271 | 102.0 | 0.887 | T | -63.3 | -35.3 | 102.0 | 0.887 | 0.0 | ||||||
6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 96.0 | 0.835 | T | -65.9 | -19.1 | 96.0 | 0.835 | 0.0 |
HOH |
3.740 |
CA |
O |
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SER | D:240 | D:271 | 100.0 | 0.87 | T | -59.1 | -20.4 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 100.0 | 0.87 | T | -67.5 | -12.8 | 100.0 | 0.87 | 0.0 |
HOH |
7.186 |
N |
O |
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SER | D:240 | D:271 | 104.0 | 0.904 | T | -66.4 | -8.6 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 93.0 | 0.809 | T | -67.6 | -23.4 | 93.0 | 0.809 | 0.0 |
HOH |
3.590 |
CA |
O |
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SER | D:240 | D:271 | 96.0 | 0.835 | T | -60.2 | -21.6 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 98.0 | 0.852 | T | -76.1 | -9.3 | 98.0 | 0.852 | 0.0 |
HOH |
3.592 |
CA |
O |
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SER | D:240 | D:271 | 98.0 | 0.852 | T | -62.0 | -22.4 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 99.0 | 0.861 | T | -81.7 | -11.8 | 99.0 | 0.861 | 0.0 |
HOH |
4.034 |
CA |
O |
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SER | D:240 | D:271 | 101.0 | 0.878 | T | -65.1 | -17.5 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 93.0 | 0.809 | T | -71.3 | -19.7 | 93.0 | 0.809 | 0.0 |
HOH |
6.977 |
N |
O |
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SER | D:240 | D:271 | 100.0 | 0.87 | T | -60.5 | -18.0 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | SER | B:240 | B:271 | 93.0 | 0.809 | T | -62.6 | -21.3 | 93.0 | 0.809 | 0.0 |
HOH |
3.842 |
CA |
O |
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SER | D:240 | D:271 | 99.0 | 0.861 | T | -60.8 | -18.0 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | SER | B:240 | D:271 | 98.0 | NA | S | -51.0 | -51.7 | 98.0 | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | ALA | A:271 | A:271 | 56.0 | 0.487 | T | -79.1 | -15.1 |