Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13906503 | . | C | A | CCDS8662.1:NM_000834.3:c.758gGc>gTc_NP_000825.2:p.253G>V | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | GLY | B:253 | B:253 | 61.0 | 0.813 | T | -131.9 | -9.6 | 61.0 | 0.813 | 0.0 | ||||||
GLY | D:253 | D:253 | 127.0 | 1.0 | 360.0 | -56.3 | 127.0 | 1.0 | 0.0 | ||||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | GLY | B:284 | B:253 | 50.0 | 0.667 | S | -85.7 | 36.8 | 50.0 | 0.667 | 0.0 | ||||||
GLY | D:284 | D:253 | 50.0 | 0.667 | S | -85.8 | 36.8 | 50.0 | 0.667 | 0.0 | |||||||||||||
5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLY | B:228 | B:253 | 64.0 | 0.853 | T | 108.3 | -15.0 | 64.0 | 0.853 | 0.0 | ||||||
GLY | D:228 | D:253 | 64.0 | 0.853 | T | 108.3 | -15.0 | 64.0 | 0.853 | 0.0 | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLY | B:228 | B:253 | 69.0 | 0.92 | T | 102.0 | -20.6 | 69.0 | 0.92 | 0.0 | ||||||
GLY | D:228 | D:253 | 69.0 | 0.92 | T | 102.1 | -20.7 | 69.0 | 0.92 | 0.0 | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLY | B:228 | B:253 | 64.0 | 0.853 | T | 88.0 | -20.6 | 64.0 | 0.853 | 0.0 | ||||||
GLY | D:228 | D:253 | 64.0 | 0.853 | T | 88.0 | -20.6 | 64.0 | 0.853 | 0.0 | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | GLY | B:228 | B:253 | 64.0 | 0.853 | T | 89.6 | -21.4 | 64.0 | 0.853 | 0.0 | ||||||
GLY | D:228 | D:253 | 53.0 | 0.707 | T | 89.6 | -21.4 | 53.0 | 0.707 | 0.0 | |||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLY | B:228 | B:253 | 81.0 | 1.0 | T | 81.3 | 3.7 | 81.0 | 1.0 | 0.0 | ||||||
GLY | D:228 | D:253 | 80.0 | 1.0 | T | 81.3 | 3.7 | 80.0 | 1.0 | 0.0 | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLY | B:284 | B:253 | 60.0 | 0.8 | T | -141.0 | 1.3 | 60.0 | 0.8 | 0.0 | ||||||
GLY | D:284 | D:253 | 61.0 | 0.813 | T | -141.0 | 1.3 | 61.0 | 0.813 | 0.0 | |||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLY | B:284 | B:253 | 50.0 | 0.667 | S | -138.0 | 36.0 | 50.0 | 0.667 | 0.0 | ||||||
GLY | D:284 | D:253 | 49.0 | 0.653 | S | -137.9 | 35.9 | 49.0 | 0.653 | 0.0 | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLY | B:284 | B:253 | 51.0 | 0.68 | T | -69.1 | -16.2 | 51.0 | 0.68 | 0.0 | ||||||
GLY | D:284 | D:253 | 50.0 | 0.667 | T | -69.1 | -16.1 | 50.0 | 0.667 | 0.0 | |||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLY | B:284 | B:253 | 66.0 | 0.88 | T | 72.1 | 29.6 | 66.0 | 0.88 | 0.0 | ||||||
GLY | D:284 | D:253 | 65.0 | 0.867 | T | 72.0 | 29.6 | 65.0 | 0.867 | 0.0 | |||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLY | B:284 | B:253 | 53.0 | 0.707 | T | 115.4 | -41.4 | 53.0 | 0.707 | 0.0 | ||||||
GLY | D:284 | D:253 | 39.0 | 0.52 | S | 110.6 | -42.3 | 39.0 | 0.52 | 0.0 | |||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLY | B:284 | B:253 | 56.0 | 0.747 | T | 121.3 | -9.3 | 56.0 | 0.747 | 0.0 | ||||||
GLY | D:284 | D:253 | 58.0 | 0.773 | T | 121.3 | -9.3 | 58.0 | 0.773 | 0.0 | |||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLY | B:284 | B:253 | 37.0 | 0.493 | S | 121.1 | -43.8 | 37.0 | 0.493 | 0.0 | ||||||
GLY | D:284 | D:253 | 66.0 | 0.88 | S | 116.5 | -34.7 | 64.0 | 0.853 | 0.027 |
B:None:0.027 |
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6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLY | B:284 | B:253 | 71.0 | 0.947 | T | 142.3 | -21.5 | 71.0 | 0.947 | 0.0 | ||||||
GLY | D:284 | D:253 | 71.0 | 0.947 | T | 142.3 | -21.5 | 71.0 | 0.947 | 0.0 | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | GLY | B:284 | B:253 | 58.0 | 0.773 | T | 131.3 | -38.0 | 58.0 | 0.773 | 0.0 | ||||||
GLY | D:284 | D:253 | 57.0 | 0.76 | T | 131.3 | -38.0 | 57.0 | 0.76 | 0.0 | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | GLY | B:227 | B:253 | 57.0 | 0.76 | T | 99.0 | -6.8 | 57.0 | 0.76 | 0.0 | ||||||
GLY | D:227 | D:253 | 58.0 | 0.773 | T | 98.1 | -16.3 | 58.0 | 0.773 | 0.0 | |||||||||||||
6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | GLY | B:220 | B:253 | 41.0 | 0.547 | T | 72.9 | 13.6 | 41.0 | 0.547 | 0.0 | ||||||
GLY | D:220 | D:253 | 40.0 | 0.533 | T | 72.9 | 13.6 | 40.0 | 0.533 | 0.0 | |||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLY | D:248 | D:248 | 60.0 | 0.8 | T | 97.2 | -31.8 | 60.0 | 0.8 | 0.0 | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLY | D:248 | D:248 | 61.0 | 0.813 | T | 97.3 | -31.8 | 61.0 | 0.813 | 0.0 | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | C:248 | B:248 | 68.0 | 0.907 | S | 92.2 | -23.5 | 68.0 | 0.907 | 0.0 | ||||||
GLY | D:248 | D:248 | 68.0 | 0.907 | T | 91.4 | -27.5 | 68.0 | 0.907 | 0.0 | |||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | C:248 | B:248 | 51.0 | 0.68 | T | 80.8 | -2.7 | 51.0 | 0.68 | 0.0 | ||||||
GLY | D:248 | D:248 | 65.0 | 0.867 | T | 89.0 | -21.4 | 65.0 | 0.867 | 0.0 | |||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | B:248 | B:248 | 80.0 | 1.0 | T | 96.6 | -30.9 | 80.0 | 1.0 | 0.0 | ||||||
GLY | D:248 | D:248 | 78.0 | 1.0 | T | 97.3 | -31.8 | 78.0 | 1.0 | 0.0 | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | B:248 | B:248 | 81.0 | 1.0 | T | 96.7 | -30.9 | 81.0 | 1.0 | 0.0 | ||||||
GLY | D:248 | D:248 | 77.0 | 1.0 | T | 97.3 | -31.8 | 77.0 | 1.0 | 0.0 | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | B:248 | B:248 | 81.0 | 1.0 | T | 96.6 | -30.9 | 81.0 | 1.0 | 0.0 | ||||||
GLY | D:248 | D:248 | 81.0 | 1.0 | T | 97.4 | -31.9 | 81.0 | 1.0 | 0.0 | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | B:248 | B:248 | 83.0 | 1.0 | T | 96.6 | -30.8 | 83.0 | 1.0 | 0.0 | ||||||
GLY | D:248 | D:248 | 80.0 | 1.0 | T | 97.3 | -31.8 | 80.0 | 1.0 | 0.0 | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | B:248 | B:248 | 81.0 | 1.0 | T | 96.6 | -30.8 | 81.0 | 1.0 | 0.0 | ||||||
GLY | D:248 | D:248 | 79.0 | 1.0 | T | 97.3 | -31.8 | 79.0 | 1.0 | 0.0 | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLY | B:248 | B:248 | 79.0 | 1.0 | T | 97.4 | -31.9 | 79.0 | 1.0 | 0.0 | ||||||
GLY | D:248 | D:248 | 79.0 | 1.0 | T | 97.5 | -31.9 | 79.0 | 1.0 | 0.0 | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLY | B:229 | B:248 | 62.0 | 0.827 | T | 91.9 | -20.9 | 62.0 | 0.827 | 0.0 | ||||||
GLY | D:229 | D:248 | 55.0 | 0.733 | T | 92.2 | -20.6 | 55.0 | 0.733 | 0.0 | |||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLY | B:229 | B:248 | 65.0 | 0.867 | T | 96.6 | -30.8 | 65.0 | 0.867 | 0.0 | ||||||
GLY | D:229 | D:248 | 47.0 | 0.627 | T | 97.3 | -31.8 | 47.0 | 0.627 | 0.0 | |||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLY | B:223 | B:253 | 59.0 | 0.787 | T | 89.8 | -6.8 | 59.0 | 0.787 | 0.0 |
HOH |
4.844 |
N |
O |
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GLY | D:223 | D:253 | 58.0 | 0.773 | T | 86.6 | -7.5 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLY | B:223 | B:253 | 61.0 | 0.813 | T | 83.1 | 1.2 | 61.0 | 0.813 | 0.0 |
HOH |
7.967 |
O |
O |
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GLY | D:223 | D:253 | 60.0 | 0.8 | T | 86.9 | -3.9 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLY | B:223 | B:253 | 57.0 | 0.76 | T | 100.2 | -16.5 | 57.0 | 0.76 | 0.0 |
HOH |
4.952 |
N |
O |
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GLY | D:223 | D:253 | 55.0 | 0.733 | T | 98.3 | -15.5 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLY | B:223 | B:253 | 56.0 | 0.747 | T | 98.1 | -16.7 | 56.0 | 0.747 | 0.0 |
HOH |
5.625 |
N |
O |
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GLY | D:223 | D:253 | 56.0 | 0.747 | T | 82.8 | -6.6 | 56.0 | 0.747 | 0.0 |
HOH |
4.631 |
N |
O |
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3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLY | B:223 | B:253 | 60.0 | 0.8 | S | 80.5 | -22.1 | 60.0 | 0.8 | 0.0 | ||||||
GLY | D:223 | D:253 | 59.0 | 0.787 | T | 86.4 | -14.3 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | GLY | C:223 | C:253 | 73.0 | 0.973 | S | -146.3 | 17.5 | 73.0 | 0.973 | 0.0 | ||||||
GLY | E:223 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLY | A:222 | A:253 | 55.0 | 0.733 | T | 91.0 | -6.4 | 55.0 | 0.733 | 0.0 | ||||||
3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLY | A:222 | A:253 | 64.0 | 0.853 | S | 100.8 | -37.0 | 64.0 | 0.853 | 0.0 |
HOH |
9.108 |
N |
O |
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6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 57.0 | 0.76 | T | 99.8 | -21.2 | 57.0 | 0.76 | 0.0 |
HOH |
9.044 |
N |
O |
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GLY | D:222 | D:253 | 52.0 | 0.693 | T | -81.0 | -4.7 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 57.0 | 0.76 | T | 86.9 | -14.9 | 57.0 | 0.76 | 0.0 | ||||||
GLY | D:222 | D:253 | 60.0 | 0.8 | T | 84.0 | -13.6 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 59.0 | 0.787 | T | 92.1 | -12.8 | 59.0 | 0.787 | 0.0 |
HOH |
7.820 |
O |
O |
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GLY | D:222 | D:253 | 60.0 | 0.8 | T | 86.7 | -11.2 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 59.0 | 0.787 | T | 75.9 | 8.2 | 59.0 | 0.787 | 0.0 |
HOH |
8.928 |
C |
O |
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GLY | D:222 | D:253 | 50.0 | 0.667 | T | -76.0 | -5.2 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 59.0 | 0.787 | T | 97.6 | -20.1 | 59.0 | 0.787 | 0.0 |
HOH |
8.962 |
N |
O |
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GLY | D:222 | D:253 | 58.0 | 0.773 | T | 97.6 | -21.3 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 59.0 | 0.787 | T | 97.6 | -18.2 | 59.0 | 0.787 | 0.0 |
HOH |
9.242 |
N |
O |
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GLY | D:222 | D:253 | 58.0 | 0.773 | T | 90.6 | -18.1 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLY | B:222 | B:253 | 57.0 | 0.76 | T | 96.9 | -22.6 | 57.0 | 0.76 | 0.0 |
HOH |
9.310 |
O |
O |
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GLY | D:222 | D:253 | 59.0 | 0.787 | T | 88.8 | -15.8 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | GLY | B:222 | D:253 | 66.0 | 0.88 | T | 98.3 | -12.3 | 66.0 | 0.88 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | GLY | A:253 | A:253 | 46.0 | 0.613 | T | 99.3 | -16.2 |