Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 13906524 . G A CCDS8662.1:NM_000834.3:c.737tCa>tTa_NP_000825.2:p.246S>L Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7eu8 2 Q13224 100.0 0.0 EM
 2021-07-28 SER B:246 B:246 90.0 0.783 H -64.7 -43.3 53.0 0.461 0.322 D:Q13224:0.322
SER D:246 D:246 93.0 0.809 H -63.7 -43.2 57.0 0.496 0.313 B:Q13224:0.313
6wi1 2 ? 99.28 0.0 EM
 2020-07-15 SER B:277 B:246 90.0 0.783 H -65.3 -29.1 56.0 0.487 0.296 D:None:0.296
SER D:277 D:246 88.0 0.765 H -65.2 -29.2 53.0 0.461 0.304 B:None:0.304
5fxg 2 Q00960 98.91 0.0 EM
 2016-05-11 SER B:221 B:246 92.0 NA H -56.4 -45.0 86.0 NA NA D:Q00960:NA
SER D:221 D:246 88.0 NA H -56.4 -44.9 83.0 NA NA B:Q00960:NA
5fxh 2 Q00960 98.91 0.0 EM
 2016-05-11 SER B:221 B:246 83.0 NA H -57.3 -53.1 83.0 NA NA
SER D:221 D:246 82.0 NA H -57.3 -53.1 82.0 NA NA
5fxi 2 Q00960 98.91 0.0 EM
 2016-05-11 SER B:221 B:246 83.0 NA H -63.5 -18.8 83.0 NA NA
SER D:221 D:246 81.0 NA H -63.6 -18.7 81.0 NA NA
5fxj 2 Q00960 98.91 0.0 EM
 2016-05-25 SER B:221 B:246 74.0 NA H -66.0 -57.6 74.0 NA NA
SER D:221 D:246 75.0 NA H -65.9 -57.7 75.0 NA NA
5fxk 2 Q00960 98.91 0.0 EM
 2016-05-11 SER B:221 B:246 75.0 NA H -64.4 -25.1 75.0 NA NA
SER D:221 D:246 76.0 NA H -64.4 -25.1 76.0 NA NA
6whr 2 Q00960 98.91 0.0 EM
 2020-08-05 SER B:277 B:246 78.0 0.678 H -93.0 -53.1 56.0 0.487 0.191 D:Q00960:0.191
SER D:277 D:246 75.0 0.652 H -93.0 -53.1 54.0 0.47 0.182 B:Q00960:0.183
6whs 2 Q00960 98.91 0.0 EM
 2020-08-05 SER B:277 B:246 77.0 0.67 T -73.0 2.5 77.0 0.67 0.0
SER D:277 D:246 79.0 0.687 T -73.1 2.5 79.0 0.687 0.0
6wht 2 Q00960 98.91 0.0 EM
 2020-08-05 SER B:277 B:246 90.0 0.783 H -60.3 -47.1 73.0 0.635 0.148 D:Q00960:0.148
SER D:277 D:246 89.0 0.774 H -60.3 -47.0 73.0 0.635 0.139 B:Q00960:0.139
6whu 2 Q00960 98.91 0.0 EM
 2020-08-05 SER B:277 B:246 89.0 0.774 H -66.3 -35.3 57.0 0.496 0.278 D:Q00960:0.278
SER D:277 D:246 90.0 0.783 H -66.4 -35.3 55.0 0.478 0.305 B:Q00960:0.304
6whv 2 Q00960 98.91 0.0 EM
 2020-08-05 SER B:277 B:246 83.0 0.722 H -68.0 -34.0 52.0 0.452 0.27 D:Q00960:0.27
SER D:277 D:246 78.0 0.678 T -99.2 -3.9 32.0 0.278 0.4 B:Q00960:0.4
6whw 2 ? 98.91 0.0 EM
 2020-07-15 SER B:277 B:246 65.0 0.565 H -65.2 -52.3 23.0 0.2 0.365 D:None:0.365
SER D:277 D:246 66.0 0.574 H -65.3 -52.2 23.0 0.2 0.374 B:None:0.374
6whx 2 ? 98.91 0.0 EM
 2020-07-15 SER B:277 B:246 68.0 0.591 H -64.2 -21.1 13.0 0.113 0.478 D:None:0.478
SER D:277 D:246 91.0 0.791 T -92.3 12.9 55.0 0.478 0.313 B:None:0.313
6why 2 ? 98.91 0.0 EM
 2020-07-15 SER B:277 B:246 82.0 0.713 H -63.4 -31.2 65.0 0.565 0.148 D:None:0.148
SER D:277 D:246 84.0 0.73 H -63.5 -31.2 69.0 0.6 0.13 B:None:0.13
6wi0 2 Q00960 98.91 0.0 EM
 2020-07-15 SER B:277 B:246 61.0 0.53 H -70.5 -26.6 61.0 0.53 0.0
SER D:277 D:246 62.0 0.539 H -70.6 -26.6 62.0 0.539 0.0
4pe5 2 Q00960 97.82 0.0 X-RAY
 2014-06-04 SER B:220 B:246 97.0 0.843 H -71.3 -29.6 97.0 0.843 0.0
SER D:220 D:246 85.0 0.739 T -61.6 -7.0 85.0 0.739 0.0
6cna 2 Q00960 99.14 0.0 EM
 2018-10-03 SER B:213 B:246 98.0 0.852 H -67.3 -32.6 98.0 0.852 0.0
SER D:213 D:246 98.0 0.852 H -67.5 -32.5 98.0 0.852 0.0
5uow 3 A7XY94 86.86 0.0 EM
 2017-03-22 SER D:241 D:241 90.0 NA H -67.6 -42.4 85.0 NA NA B:B7ZSK1:NA
5up2 3 A7XY94 86.86 0.0 EM
 2017-03-22 SER D:241 D:241 92.0 NA H -67.6 -42.4 92.0 NA NA
5iou 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER C:241 B:241 89.0 NA H -90.0 -27.9 67.0 NA NA D:A7XY94:NA
SER D:241 D:241 90.0 NA H -100.5 -23.7 78.0 NA NA C:A7XY94:NA
5iov 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER C:241 B:241 91.0 NA H -82.9 -34.1 86.0 NA NA D:A7XY94:NA
SER D:241 D:241 90.0 NA H -88.3 -32.3 83.0 NA NA C:A7XY94:NA
5ipq 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER B:241 B:241 72.0 NA H -67.4 -42.2 72.0 NA NA
SER D:241 D:241 71.0 NA H -67.6 -42.4 71.0 NA NA
5ipr 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER B:241 B:241 71.0 NA H -67.5 -42.2 71.0 NA NA
SER D:241 D:241 72.0 NA H -67.6 -42.4 72.0 NA NA
5ips 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER B:241 B:241 73.0 NA H -67.5 -42.2 73.0 NA NA
SER D:241 D:241 72.0 NA H -67.6 -42.5 72.0 NA NA
5ipt 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER B:241 B:241 72.0 NA H -67.5 -42.2 72.0 NA NA
SER D:241 D:241 73.0 NA H -67.6 -42.5 73.0 NA NA
5ipu 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER B:241 B:241 70.0 NA H -67.4 -42.2 70.0 NA NA
SER D:241 D:241 72.0 NA H -67.6 -42.4 72.0 NA NA
5ipv 2 A7XY94 85.78 0.0 EM
 2016-04-20 SER B:241 B:241 71.0 NA H -67.8 -42.4 56.0 NA NA D:A7XY94:NA
SER D:241 D:241 71.0 NA H -67.7 -42.4 68.0 NA NA B:A7XY94:NA
4tll 2 A7XY94 87.47 0.0 X-RAY
 2014-07-02 SER B:222 B:241 98.0 0.852 H -66.9 -35.4 33.0 0.287 0.565 D:A7XY94:0.565
SER D:222 D:241 92.0 0.8 H -65.2 -35.8 41.0 0.357 0.443 B:A7XY94:0.443
4tlm 2 A7XY94 87.47 0.0 X-RAY
 2014-07-02 SER B:222 B:241 76.0 NA H -67.4 -42.2 45.0 NA NA D:A7XY94:NA
SER D:222 D:241 88.0 NA H -67.6 -42.5 62.0 NA NA B:A7XY94:NA
5ewj 2 Q13224 99.73 0.0 X-RAY
 2016-03-02 SER B:216 B:246 89.0 0.774 H -55.2 -36.0 89.0 0.774 0.0 HOH
 7.094
 N
 O
SER D:216 D:246 83.0 0.722 H -64.3 -35.6 NA NA NA
5ewl 2 Q13224 99.73 0.0 X-RAY
 2016-03-02 SER B:216 B:246 81.0 0.704 H -51.8 -37.3 81.0 0.704 0.0 HOH
 5.260
 N
 O
SER D:216 D:246 76.0 0.661 H -68.7 -35.0 NA NA NA
5ewm 2 Q13224 99.73 0.0 X-RAY
 2016-03-02 SER B:216 B:246 91.0 0.791 H -51.7 -39.1 91.0 0.791 0.0 HOH
 3.493
 O
 O
SER D:216 D:246 86.0 0.748 H -63.6 -37.0 NA NA NA
3qel 2 Q00960 99.45 0.0 X-RAY
 2011-06-15 SER B:216 B:246 93.0 0.809 T -60.7 -6.2 93.0 0.809 0.0 HOH
 5.280
 N
 O
SER D:216 D:246 89.0 0.774 H -79.2 -24.6 89.0 0.774 0.0
3qem 2 Q00960 99.45 0.0 X-RAY
 2011-06-15 SER B:216 B:246 83.0 0.722 T -69.4 22.1 83.0 0.722 0.0
SER D:216 D:246 68.0 NA T -91.8 -67.0 NA NA NA
5b3j 2 Q00960 99.45 0.0 X-RAY
 2016-05-11 SER C:216 NA:NA DO NA DO DO DO NA NA NA
SER E:216 D:246 45.0 NA -109.8 114.4 NA NA NA
3jpw 1 Q00960 99.45 0.0 X-RAY
 2009-12-08 SER A:215 A:246 90.0 0.783 T -108.8 27.7 90.0 0.783 0.0 CL
 6.019
 OG
 CL
3jpy 1 Q00960 99.45 0.0 X-RAY
 2009-12-08 SER A:215 A:246 103.0 0.896 T -86.0 38.8 103.0 0.896 0.0
6e7r 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 79.0 0.687 H -62.6 -26.3 79.0 0.687 0.0 HOH
 5.387
 N
 O
SER D:215 D:246 85.0 0.739 H -47.6 -43.7 NA NA NA
6e7s 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 81.0 0.704 H -80.8 -6.1 81.0 0.704 0.0 HOH
 4.010
 C
 O
SER D:215 D:246 86.0 0.748 H -71.2 -17.8 NA NA NA
6e7t 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 92.0 0.8 T -57.0 -17.3 92.0 0.8 0.0 HOH
 5.184
 N
 O
SER D:215 D:246 89.0 0.774 H -51.8 -26.0 NA NA NA
6e7u 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 76.0 0.661 H -66.2 -20.6 76.0 0.661 0.0 HOH
 5.562
 N
 O
SER D:215 D:246 74.0 0.643 H -62.7 -27.2 NA NA NA
6e7v 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 78.0 0.678 H -59.0 -27.1 78.0 0.678 0.0 HOH
 5.368
 N
 O
SER D:215 D:246 85.0 0.739 H -54.6 -33.7 NA NA NA
6e7w 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 79.0 0.687 H -65.1 -24.7 79.0 0.687 0.0 HOH
 5.102
 N
 O
SER D:215 D:246 87.0 0.757 H -61.7 -31.3 NA NA NA
6e7x 2 Q00960 99.45 0.0 X-RAY
 2019-01-30 SER B:215 B:246 78.0 0.678 H -59.4 -27.7 78.0 0.678 0.0
SER D:215 D:246 87.0 0.757 H -46.4 -40.7 NA NA NA
5tpz 2 Q00960 99.45 0.0 X-RAY
 2016-12-14 SER B:215 D:246 83.0 NA H -56.6 -49.6 83.0 NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q13224-f1 1 Q13224 100.0 0.0 SER A:246 A:246 72.0 0.626 H -65.8 -23.9