Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13906555 | . | C | A | CCDS8662.1:NM_000834.3:c.706Gaa>Taa_NP_000825.2:p.236E>* | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
---|---|---|---|---|---|---|---|
|
|
|
|
PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | GLU | B:236 | B:236 | 46.0 | NA | H | -70.4 | -34.7 | 46.0 | NA | NA | ||||||
GLU | D:236 | D:236 | 43.0 | NA | H | -75.2 | -31.2 | 43.0 | NA | NA | |||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | GLU | B:267 | B:236 | 17.0 | 0.089 | H | -60.9 | -36.5 | 17.0 | 0.089 | 0.0 | ||||||
GLU | D:267 | D:236 | 18.0 | 0.095 | H | -60.9 | -36.5 | 18.0 | 0.095 | 0.0 | |||||||||||||
5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:211 | B:236 | 43.0 | NA | H | -58.8 | -34.9 | 43.0 | NA | NA | ||||||
GLU | D:211 | D:236 | 43.0 | NA | H | -58.7 | -34.9 | 43.0 | NA | NA | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:211 | B:236 | 40.0 | NA | H | -64.3 | -37.4 | 40.0 | NA | NA | ||||||
GLU | D:211 | D:236 | 40.0 | NA | H | -64.4 | -37.3 | 40.0 | NA | NA | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:211 | B:236 | 29.0 | NA | H | -59.2 | -32.1 | 29.0 | NA | NA | ||||||
GLU | D:211 | D:236 | 27.0 | NA | H | -59.3 | -32.1 | 27.0 | NA | NA | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | GLU | B:211 | B:236 | 38.0 | NA | T | -71.9 | -14.5 | 38.0 | NA | NA | ||||||
GLU | D:211 | D:236 | 39.0 | NA | T | -71.8 | -14.6 | 39.0 | NA | NA | |||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLU | B:211 | B:236 | 43.0 | NA | H | -57.9 | -36.6 | 43.0 | NA | NA | ||||||
GLU | D:211 | D:236 | 44.0 | NA | H | -57.9 | -36.6 | 44.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:267 | B:236 | 34.0 | 0.179 | H | -53.3 | -23.3 | 34.0 | 0.179 | 0.0 | ||||||
GLU | D:267 | D:236 | 34.0 | 0.179 | H | -53.4 | -23.2 | 34.0 | 0.179 | 0.0 | |||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:267 | B:236 | 32.0 | NA | H | -66.2 | -34.0 | 32.0 | NA | NA | ||||||
GLU | D:267 | D:236 | 31.0 | NA | H | -66.2 | -34.0 | 31.0 | NA | NA | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:267 | B:236 | 91.0 | 0.479 | H | -60.3 | -27.9 | 91.0 | 0.479 | 0.0 | ||||||
GLU | D:267 | D:236 | 90.0 | 0.474 | H | -60.3 | -27.9 | 90.0 | 0.474 | 0.0 | |||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:267 | B:236 | 47.0 | 0.247 | H | -57.6 | -34.1 | 47.0 | 0.247 | 0.0 | ||||||
GLU | D:267 | D:236 | 50.0 | 0.263 | H | -57.6 | -34.1 | 50.0 | 0.263 | 0.0 | |||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLU | B:267 | B:236 | 56.0 | 0.295 | H | -59.3 | -25.3 | 56.0 | 0.295 | 0.0 | ||||||
GLU | D:267 | D:236 | 53.0 | 0.279 | H | -58.6 | -34.1 | 53.0 | 0.279 | 0.0 | |||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:267 | B:236 | 47.0 | 0.247 | H | -53.7 | -38.1 | 47.0 | 0.247 | 0.0 | ||||||
GLU | D:267 | D:236 | 47.0 | 0.247 | H | -53.8 | -38.1 | 47.0 | 0.247 | 0.0 | |||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:267 | B:236 | 65.0 | 0.342 | H | -53.3 | -46.8 | 65.0 | 0.342 | 0.0 | ||||||
GLU | D:267 | D:236 | 21.0 | NA | H | -70.0 | -24.8 | 21.0 | NA | NA | |||||||||||||
6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:267 | B:236 | 107.0 | 0.563 | H | -70.0 | -23.8 | 107.0 | 0.563 | 0.0 | ||||||
GLU | D:267 | D:236 | 109.0 | 0.574 | H | -70.1 | -23.7 | 109.0 | 0.574 | 0.0 | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | GLU | B:267 | B:236 | 66.0 | 0.347 | H | -61.3 | -26.1 | 66.0 | 0.347 | 0.0 | ||||||
GLU | D:267 | D:236 | 64.0 | 0.337 | H | -61.2 | -26.1 | 64.0 | 0.337 | 0.0 | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | GLU | B:210 | B:236 | 44.0 | 0.232 | H | -71.5 | -35.9 | 25.0 | 0.132 | 0.1 |
A:P35439:0.1 |
QEL |
2.388 |
OE2 |
O2 |
|
GLU | D:210 | D:236 | 40.0 | 0.211 | H | -70.2 | -42.0 | 22.0 | 0.116 | 0.095 |
C:P35439:0.095 |
QEL |
2.293 |
OE2 |
O2 |
||||||||
6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | GLU | B:203 | B:236 | 44.0 | 0.232 | H | -59.2 | -42.8 | 44.0 | 0.232 | 0.0 | ||||||
GLU | D:203 | D:236 | 44.0 | 0.232 | H | -59.3 | -42.7 | 44.0 | 0.232 | 0.0 | |||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLU | D:231 | D:231 | 32.0 | NA | H | -56.4 | -39.7 | 32.0 | NA | NA | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLU | D:231 | D:231 | 32.0 | NA | H | -56.4 | -39.7 | 32.0 | NA | NA | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | C:231 | B:231 | 35.0 | NA | H | -76.8 | -36.4 | 35.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 37.0 | NA | H | -77.2 | -36.3 | 37.0 | NA | NA | |||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | C:231 | B:231 | 34.0 | NA | H | -81.9 | -34.3 | 34.0 | NA | NA |
QEM |
6.741 |
CB |
C19 |
||
GLU | D:231 | D:231 | 31.0 | NA | H | -80.3 | -36.5 | 31.0 | NA | NA |
QEM |
6.740 |
CB |
O |
|||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:231 | B:231 | 53.0 | NA | H | -56.2 | -38.5 | 53.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 54.0 | NA | H | -56.6 | -39.6 | 54.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:231 | B:231 | 53.0 | NA | H | -56.2 | -38.4 | 53.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 55.0 | NA | H | -56.7 | -39.6 | 55.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:231 | B:231 | 53.0 | NA | H | -56.4 | -38.4 | 53.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 54.0 | NA | H | -56.6 | -39.6 | 54.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:231 | B:231 | 54.0 | NA | H | -56.2 | -38.5 | 54.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 53.0 | NA | H | -56.6 | -39.6 | 53.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:231 | B:231 | 52.0 | NA | H | -56.2 | -38.5 | 52.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 55.0 | NA | H | -56.6 | -39.6 | 55.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLU | B:231 | B:231 | 54.0 | NA | H | -56.5 | -39.7 | 54.0 | NA | NA | ||||||
GLU | D:231 | D:231 | 55.0 | NA | H | -56.6 | -39.8 | 55.0 | NA | NA | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLU | B:212 | B:231 | 32.0 | 0.168 | H | -60.8 | -44.8 | 23.0 | 0.121 | 0.047 |
A:C0KD18:0.047 |
QEM |
2.506 |
OE2 |
O |
|
GLU | D:212 | D:231 | 32.0 | 0.168 | H | -61.6 | -45.4 | 32.0 | 0.168 | 0.0 |
QEM |
2.492 |
OE2 |
O |
|||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLU | B:212 | B:231 | 34.0 | 0.179 | H | -56.2 | -38.5 | 21.0 | 0.111 | 0.068 |
A:C0KD18:0.068 |
QEM |
2.930 |
OE2 |
O |
|
GLU | D:212 | D:231 | 18.0 | NA | H | -56.5 | -39.7 | 18.0 | NA | NA |
QEM |
6.499 |
CB |
O |
|||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLU | B:206 | B:236 | 40.0 | 0.211 | H | -69.6 | -43.2 | 25.0 | 0.132 | 0.079 |
A:Q91977:0.079 |
QEL HOH |
2.551 3.879 |
OE2 OE2 |
O2 O |
|
GLU | D:206 | D:236 | 41.0 | 0.216 | H | -70.2 | -43.2 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLU | B:206 | B:236 | 41.0 | 0.216 | H | -68.0 | -42.7 | 30.0 | 0.158 | 0.058 |
A:Q91977:0.058 |
5SL HOH |
2.778 5.279 |
OE2 N |
N5 O |
|
GLU | D:206 | D:236 | 38.0 | 0.2 | H | -67.3 | -42.8 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLU | B:206 | B:236 | 38.0 | 0.2 | H | -71.8 | -39.0 | 31.0 | 0.163 | 0.037 |
A:Q91977:0.037 |
HOH |
3.014 |
OE2 |
O |
|
GLU | D:206 | D:236 | 39.0 | 0.205 | H | -72.1 | -38.7 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLU | B:206 | B:236 | 37.0 | 0.195 | H | -69.7 | -42.1 | 26.0 | 0.137 | 0.058 |
A:Q91977:0.058 |
QEL HOH |
2.448 3.694 |
OE2 OE2 |
O2 O |
|
GLU | D:206 | D:236 | 43.0 | 0.226 | H | -64.9 | -45.0 | 43.0 | 0.226 | 0.0 |
QEL HOH |
2.483 3.842 |
OE2 OE2 |
O2 O |
|||||||||
3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLU | B:206 | B:236 | 41.0 | 0.216 | H | -64.3 | -41.3 | 21.0 | 0.111 | 0.105 |
A:Q91977:0.105 |
QEM |
2.718 |
OE2 |
O |
|
GLU | D:206 | D:236 | 41.0 | 0.216 | H | -74.5 | -41.0 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | GLU | C:206 | C:236 | 24.0 | NA | H | -74.5 | -24.3 | 24.0 | NA | NA | ||||||
GLU | E:206 | D:236 | 44.0 | NA | H | -75.1 | -24.8 | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLU | A:205 | A:236 | 42.0 | 0.221 | H | -69.0 | -41.9 | 42.0 | 0.221 | 0.0 |
HOH |
6.256 |
N |
O |
||
3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLU | A:205 | A:236 | 48.0 | 0.253 | H | -62.0 | -44.0 | 48.0 | 0.253 | 0.0 |
HOH |
9.223 |
N |
O |
||
6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 40.0 | 0.211 | H | -63.9 | -41.1 | 28.0 | 0.147 | 0.064 |
A:A0A1L8F5J9:0.063 |
HYS CL HOH |
2.846 5.119 2.869 |
OE2 N OE2 |
N20 CL O |
|
GLU | D:205 | D:236 | 40.0 | 0.211 | H | -59.1 | -44.7 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 40.0 | 0.211 | H | -74.8 | -40.6 | 26.0 | 0.137 | 0.074 |
A:A0A1L8F5J9:0.074 |
HZ4 CL HOH |
3.107 5.550 2.720 |
OE2 N OE2 |
N22 CL O |
|
GLU | D:205 | D:236 | 43.0 | 0.226 | H | -73.6 | -45.4 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 40.0 | 0.211 | H | -69.1 | -40.5 | 27.0 | 0.142 | 0.069 |
A:A0A1L8F5J9:0.068 |
HYY HOH |
2.986 2.761 |
OE2 OE2 |
N23 O |
|
GLU | D:205 | D:236 | 39.0 | 0.205 | H | -64.1 | -47.5 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 40.0 | 0.211 | H | -64.9 | -36.0 | 26.0 | 0.137 | 0.074 |
A:A0A1L8F5J9:0.074 |
HX7 CL HOH |
2.848 5.199 2.788 |
OE2 N OE2 |
NAV CL O |
|
GLU | D:205 | D:236 | 40.0 | 0.211 | H | -63.0 | -44.4 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 41.0 | 0.216 | H | -70.0 | -36.9 | 30.0 | 0.158 | 0.058 |
A:A0A1L8F5J9:0.058 |
T88 CL HOH |
2.884 5.589 4.620 |
OE2 N CG |
N24 CL O |
|
GLU | D:205 | D:236 | 42.0 | 0.221 | H | -63.4 | -41.8 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 40.0 | 0.211 | H | -67.9 | -45.1 | 27.0 | 0.142 | 0.069 |
A:A0A1L8F5J9:0.068 |
HXM CL HOH |
2.745 5.417 4.876 |
OE2 N N |
N23 CL O |
|
GLU | D:205 | D:236 | 43.0 | 0.226 | H | -62.4 | -47.3 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLU | B:205 | B:236 | 40.0 | 0.211 | H | -65.7 | -42.4 | 27.0 | 0.142 | 0.069 |
A:A0A1L8F5J9:0.068 |
T97 HOH |
2.896 3.863 |
OE2 CG |
N24 O |
|
GLU | D:205 | D:236 | 41.0 | 0.216 | H | -61.3 | -46.4 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | GLU | B:205 | D:236 | 47.0 | 0.247 | H | -69.0 | -31.8 | 36.0 | 0.189 | 0.058 |
A:Q91977:0.058 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | GLU | A:236 | A:236 | 36.0 | 0.189 | H | -58.1 | -38.4 |