Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13906612 | . | G | A | CCDS8662.1:NM_000834.3:c.649Cag>Tag_NP_000825.2:p.217Q>* | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | GLN | B:217 | B:217 | 25.0 | NA | H | -63.5 | -42.5 | 8.0 | NA | NA |
D:Q13224:NA |
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GLN | D:217 | D:217 | 33.0 | NA | H | -64.5 | -41.3 | 15.0 | NA | NA |
B:Q13224:NA |
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6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | GLN | B:248 | B:217 | 1.0 | NA | H | -80.7 | -32.4 | 1.0 | NA | NA | ||||||
GLN | D:248 | D:217 | 1.0 | NA | H | -80.7 | -32.3 | 1.0 | NA | NA | |||||||||||||
5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:192 | B:217 | 64.0 | NA | H | -69.6 | -41.4 | 31.0 | NA | NA |
D:Q00960:NA |
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GLN | D:192 | D:217 | 64.0 | NA | H | -69.7 | -41.3 | 31.0 | NA | NA |
B:Q00960:NA |
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5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:192 | B:217 | 46.0 | NA | H | -63.5 | -33.3 | 46.0 | NA | NA | ||||||
GLN | D:192 | D:217 | 48.0 | NA | H | -63.5 | -33.4 | 48.0 | NA | NA | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:192 | B:217 | 24.0 | NA | H | -71.7 | -53.2 | 24.0 | NA | NA | ||||||
GLN | D:192 | D:217 | 23.0 | NA | H | -71.7 | -53.2 | 23.0 | NA | NA | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | GLN | B:192 | B:217 | 21.0 | NA | H | -68.0 | -54.7 | 21.0 | NA | NA | ||||||
GLN | D:192 | D:217 | 19.0 | NA | H | -68.1 | -54.7 | 19.0 | NA | NA | |||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:192 | B:217 | 38.0 | NA | H | -68.8 | -31.8 | 38.0 | NA | NA | ||||||
GLN | D:192 | D:217 | 36.0 | NA | H | -68.8 | -31.8 | 36.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:248 | B:217 | 88.0 | 0.489 | H | -53.3 | -34.0 | 44.0 | 0.244 | 0.245 |
D:Q00960:0.244 |
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GLN | D:248 | D:217 | 89.0 | 0.494 | H | -53.4 | -33.9 | 46.0 | 0.256 | 0.238 |
B:Q00960:0.239 |
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6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:248 | B:217 | 36.0 | NA | H | -56.6 | -21.5 | 36.0 | NA | NA | ||||||
GLN | D:248 | D:217 | 35.0 | NA | H | -56.5 | -21.5 | 35.0 | NA | NA | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:248 | B:217 | 30.0 | NA | H | -63.5 | -49.7 | 11.0 | NA | NA |
D:Q00960:NA |
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GLN | D:248 | D:217 | 28.0 | NA | H | -63.4 | -49.7 | 11.0 | NA | NA |
B:Q00960:NA |
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6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:248 | B:217 | 24.0 | NA | H | -66.4 | -22.2 | 24.0 | NA | NA | ||||||
GLN | D:248 | D:217 | 23.0 | NA | H | -66.4 | -22.2 | 23.0 | NA | NA | |||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:248 | B:217 | 36.0 | NA | T | -67.6 | -2.0 | 36.0 | NA | NA | ||||||
GLN | D:248 | D:217 | 90.0 | 0.5 | H | -59.0 | -34.8 | 28.0 | 0.156 | 0.344 |
B:Q00960:0.344 |
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6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:248 | B:217 | 69.0 | 0.383 | H | -52.1 | -46.8 | 30.0 | 0.167 | 0.216 |
D:None:0.217 |
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GLN | D:248 | D:217 | 70.0 | 0.389 | H | -52.2 | -46.9 | 30.0 | 0.167 | 0.222 |
B:None:0.222 |
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6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:248 | B:217 | 107.0 | 0.594 | H | -50.1 | -27.5 | 36.0 | 0.2 | 0.394 |
D:None:0.394 |
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GLN | D:248 | D:217 | 87.0 | 0.483 | H | -55.7 | -42.4 | 47.0 | 0.261 | 0.222 |
B:None:0.222 |
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6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:248 | B:217 | 68.0 | NA | H | -69.1 | -41.4 | 59.0 | NA | NA |
D:None:NA |
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GLN | D:248 | D:217 | 69.0 | NA | H | -69.2 | -41.4 | 58.0 | NA | NA |
B:None:NA |
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6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:248 | B:217 | 74.0 | 0.411 | H | -61.6 | -64.0 | 74.0 | 0.411 | 0.0 | ||||||
GLN | D:248 | D:217 | 74.0 | 0.411 | H | -61.6 | -64.0 | 74.0 | 0.411 | 0.0 | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | GLN | B:191 | B:217 | 88.0 | 0.489 | H | -57.5 | -42.4 | 45.0 | 0.25 | 0.239 |
D:Q00960:0.239 |
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GLN | D:191 | D:217 | 78.0 | 0.433 | H | -52.9 | -46.0 | 40.0 | 0.222 | 0.211 |
B:Q00960:0.211 |
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6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | GLN | B:184 | B:217 | 65.0 | 0.361 | H | -53.9 | -38.9 | 59.0 | 0.328 | 0.033 |
D:Q00960:0.033 |
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GLN | D:184 | D:217 | 67.0 | 0.372 | H | -53.8 | -39.0 | 59.0 | 0.328 | 0.044 |
B:Q00960:0.044 |
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5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLN | D:212 | D:212 | 50.0 | NA | H | -63.4 | -43.9 | 50.0 | NA | NA | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLN | D:212 | D:212 | 49.0 | NA | H | -63.4 | -43.9 | 49.0 | NA | NA | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | C:212 | B:212 | 54.0 | NA | H | -65.8 | -35.5 | 37.0 | NA | NA |
D:A7XY94:NA |
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GLN | D:212 | D:212 | 56.0 | NA | H | -65.6 | -36.5 | 53.0 | NA | NA |
C:A7XY94:NA |
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5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | C:212 | B:212 | 61.0 | NA | H | -65.7 | -35.5 | 61.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 64.0 | NA | H | -66.1 | -35.9 | 64.0 | NA | NA | |||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:212 | B:212 | 45.0 | NA | H | -63.8 | -40.8 | 45.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 39.0 | NA | H | -64.2 | -40.3 | 39.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:212 | B:212 | 44.0 | NA | H | -63.8 | -40.8 | 44.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 40.0 | NA | H | -64.3 | -40.2 | 40.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:212 | B:212 | 46.0 | NA | H | -63.8 | -40.8 | 46.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 40.0 | NA | H | -64.2 | -40.4 | 40.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:212 | B:212 | 44.0 | NA | H | -63.9 | -40.7 | 44.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 40.0 | NA | H | -64.3 | -40.3 | 40.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:212 | B:212 | 43.0 | NA | H | -63.9 | -40.7 | 43.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 40.0 | NA | H | -64.2 | -40.3 | 40.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:212 | B:212 | 39.0 | NA | H | -64.4 | -40.2 | 39.0 | NA | NA | ||||||
GLN | D:212 | D:212 | 41.0 | NA | H | -64.3 | -40.3 | 38.0 | NA | NA |
B:A7XY94:NA |
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4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLN | B:193 | B:212 | 87.0 | 0.483 | H | -58.8 | -50.6 | 25.0 | 0.139 | 0.344 |
D:A7XY94:0.344 |
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GLN | D:193 | D:212 | 74.0 | 0.411 | H | -58.9 | -48.9 | 27.0 | 0.15 | 0.261 |
B:A7XY94:0.261 |
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4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLN | B:193 | B:212 | 86.0 | 0.478 | H | -63.8 | -40.8 | 16.0 | 0.089 | 0.389 |
D:A7XY94:0.389 |
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GLN | D:193 | D:212 | 27.0 | NA | H | -64.3 | -40.3 | 11.0 | NA | NA |
B:A7XY94:NA |
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5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLN | B:187 | B:217 | 73.0 | 0.406 | H | -57.4 | -43.6 | 73.0 | 0.406 | 0.0 |
HOH |
6.966 |
C |
O |
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GLN | D:187 | D:217 | 58.0 | 0.322 | H | -57.1 | -43.8 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLN | B:187 | B:217 | 74.0 | 0.411 | H | -56.1 | -43.8 | 74.0 | 0.411 | 0.0 |
HOH |
7.434 |
NE2 |
O |
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GLN | D:187 | D:217 | 58.0 | 0.322 | H | -56.0 | -44.3 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLN | B:187 | B:217 | 77.0 | 0.428 | H | -56.0 | -48.2 | 77.0 | 0.428 | 0.0 |
HOH |
9.267 |
OE1 |
O |
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GLN | D:187 | D:217 | 59.0 | 0.328 | H | -55.9 | -48.4 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLN | B:187 | B:217 | 79.0 | 0.439 | H | -52.8 | -45.6 | 79.0 | 0.439 | 0.0 |
HOH |
7.542 |
N |
O |
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GLN | D:187 | D:217 | 87.0 | 0.483 | H | -47.8 | -42.0 | 87.0 | 0.483 | 0.0 | |||||||||||||
3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLN | B:187 | B:217 | 74.0 | 0.411 | H | -44.8 | -48.4 | 74.0 | 0.411 | 0.0 | ||||||
GLN | D:187 | D:217 | 86.0 | 0.478 | H | -50.5 | -62.6 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | GLN | C:187 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
GLN | E:187 | D:217 | 151.0 | NA | 360.0 | 95.6 | NA | NA | NA | ||||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLN | A:186 | A:217 | 88.0 | 0.489 | H | -42.0 | -47.0 | 88.0 | 0.489 | 0.0 |
CL |
7.654 |
N |
CL |
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3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLN | A:186 | A:217 | 40.0 | NA | H | -38.9 | -58.5 | 40.0 | NA | NA | ||||||
6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 73.0 | 0.406 | H | -54.4 | -44.8 | 73.0 | 0.406 | 0.0 |
HOH |
7.607 |
N |
O |
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GLN | D:186 | D:217 | 58.0 | 0.322 | H | -52.0 | -46.0 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 65.0 | 0.361 | H | -59.9 | -40.3 | 65.0 | 0.361 | 0.0 |
HOH |
7.366 |
N |
O |
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GLN | D:186 | D:217 | 70.0 | 0.389 | H | -64.5 | -39.5 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 78.0 | 0.433 | H | -59.6 | -44.3 | 78.0 | 0.433 | 0.0 |
HOH |
7.469 |
N |
O |
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GLN | D:186 | D:217 | 78.0 | 0.433 | H | -58.9 | -44.1 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 69.0 | 0.383 | H | -57.8 | -50.3 | 69.0 | 0.383 | 0.0 |
HOH |
7.787 |
N |
O |
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GLN | D:186 | D:217 | 53.0 | 0.294 | H | -59.0 | -50.8 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 73.0 | 0.406 | H | -61.0 | -42.6 | 73.0 | 0.406 | 0.0 |
HOH |
7.537 |
N |
O |
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GLN | D:186 | D:217 | 55.0 | 0.306 | H | -58.7 | -43.6 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 61.0 | 0.339 | H | -60.9 | -40.2 | 61.0 | 0.339 | 0.0 |
HOH |
7.442 |
N |
O |
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GLN | D:186 | D:217 | 69.0 | 0.383 | H | -66.0 | -39.3 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:186 | B:217 | 66.0 | 0.367 | H | -57.9 | -47.1 | 66.0 | 0.367 | 0.0 |
HOH |
7.517 |
N |
O |
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GLN | D:186 | D:217 | 73.0 | 0.406 | H | -48.9 | -48.5 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | GLN | B:186 | D:217 | 47.0 | NA | H | -50.9 | -50.1 | 47.0 | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | GLN | A:217 | A:217 | 55.0 | 0.306 | H | -59.4 | -37.6 |