Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13906723 | . | G | A | CCDS8662.1:NM_000834.3:c.538Cag>Tag_NP_000825.2:p.180Q>* | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | GLN | B:180 | B:180 | 81.0 | NA | H | -64.0 | -40.9 | 81.0 | NA | NA | ||||||
GLN | D:180 | D:180 | 88.0 | NA | H | -64.5 | -42.9 | 88.0 | NA | NA | |||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | GLN | B:211 | B:180 | 124.0 | 0.689 | H | -56.5 | -25.6 | 82.0 | 0.456 | 0.233 |
A:None:0.233 |
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GLN | D:211 | D:180 | 121.0 | 0.672 | H | -56.4 | -25.7 | 76.0 | 0.422 | 0.25 |
C:None:0.25 |
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5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:155 | B:180 | 83.0 | NA | H | -59.0 | -21.7 | 83.0 | NA | NA | ||||||
GLN | D:155 | D:180 | 81.0 | NA | H | -59.0 | -21.7 | 81.0 | NA | NA | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:155 | B:180 | 84.0 | NA | H | -57.5 | -23.4 | 84.0 | NA | NA | ||||||
GLN | D:155 | D:180 | 81.0 | NA | H | -57.6 | -23.3 | 81.0 | NA | NA | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:155 | B:180 | 78.0 | NA | H | -67.3 | -22.8 | 78.0 | NA | NA | ||||||
GLN | D:155 | D:180 | 79.0 | NA | H | -67.3 | -22.8 | 79.0 | NA | NA | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | GLN | B:155 | B:180 | 80.0 | NA | H | -61.1 | -35.0 | 80.0 | NA | NA | ||||||
GLN | D:155 | D:180 | 81.0 | NA | H | -61.1 | -35.0 | 81.0 | NA | NA | |||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | GLN | B:155 | B:180 | 80.0 | NA | H | -59.0 | -32.9 | 80.0 | NA | NA | ||||||
GLN | D:155 | D:180 | 81.0 | NA | H | -59.1 | -32.9 | 81.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:211 | B:180 | 84.0 | 0.467 | H | -65.7 | -12.5 | 84.0 | 0.467 | 0.0 | ||||||
GLN | D:211 | D:180 | 81.0 | 0.45 | H | -65.6 | -12.5 | 81.0 | 0.45 | 0.0 | |||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:211 | B:180 | 109.0 | 0.606 | H | -60.6 | -43.9 | 109.0 | 0.606 | 0.0 | ||||||
GLN | D:211 | D:180 | 108.0 | 0.6 | H | -60.6 | -43.9 | 108.0 | 0.6 | 0.0 | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:211 | B:180 | 63.0 | NA | H | -54.4 | -46.3 | 63.0 | NA | NA | ||||||
GLN | D:211 | D:180 | 63.0 | NA | H | -54.3 | -46.3 | 63.0 | NA | NA | |||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:211 | B:180 | 113.0 | 0.628 | H | -80.0 | -24.6 | 110.0 | 0.611 | 0.017 |
A:P35439:0.017 |
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GLN | D:211 | D:180 | 114.0 | 0.633 | H | -80.0 | -24.6 | 109.0 | 0.606 | 0.027 |
C:P35439:0.028 |
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6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | GLN | B:211 | B:180 | 92.0 | 0.511 | H | -59.5 | -41.8 | 92.0 | 0.511 | 0.0 | ||||||
GLN | D:211 | D:180 | 87.0 | 0.483 | H | -54.0 | -46.8 | 55.0 | 0.306 | 0.177 |
C:P35439:0.178 |
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6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:211 | B:180 | 119.0 | 0.661 | H | -56.0 | -43.4 | 89.0 | 0.494 | 0.167 |
A:None:0.167 |
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GLN | D:211 | D:180 | 119.0 | 0.661 | H | -56.0 | -43.5 | 86.0 | 0.478 | 0.183 |
C:None:0.183 |
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6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:211 | B:180 | 164.0 | 0.911 | T | -67.5 | -4.0 | 124.0 | 0.689 | 0.222 |
A:None:0.222 |
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GLN | D:211 | D:180 | 160.0 | 0.889 | H | -66.6 | -1.4 | 101.0 | 0.561 | 0.328 |
C:None:0.328 |
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6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:211 | B:180 | 37.0 | NA | H | -61.2 | -40.3 | 37.0 | NA | NA | ||||||
GLN | D:211 | D:180 | 37.0 | NA | H | -61.2 | -40.3 | 37.0 | NA | NA | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | GLN | B:211 | B:180 | 110.0 | 0.611 | H | -63.0 | -39.8 | 110.0 | 0.611 | 0.0 | ||||||
GLN | D:211 | D:180 | 107.0 | 0.594 | H | -63.0 | -39.8 | 107.0 | 0.594 | 0.0 | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | GLN | B:154 | B:180 | 38.0 | NA | H | -63.5 | -48.5 | 38.0 | NA | NA | ||||||
GLN | D:154 | D:180 | 109.0 | 0.606 | H | -73.0 | -44.7 | 100.0 | 0.556 | 0.05 |
C:P35439:0.05 |
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6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | GLN | B:147 | B:180 | 39.0 | NA | H | -63.1 | -61.2 | 39.0 | NA | NA | ||||||
GLN | D:147 | D:180 | 39.0 | NA | H | -63.1 | -61.2 | 39.0 | NA | NA | |||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLN | D:175 | D:175 | 56.0 | NA | H | -64.4 | -44.6 | 56.0 | NA | NA | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | GLN | D:175 | D:175 | 57.0 | NA | H | -64.4 | -44.6 | 57.0 | NA | NA | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | C:175 | B:175 | 85.0 | NA | H | -63.0 | -46.6 | 85.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 84.0 | NA | H | -62.9 | -51.3 | 84.0 | NA | NA | |||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | C:175 | B:175 | 85.0 | NA | H | -62.8 | -48.9 | 85.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 85.0 | NA | H | -62.8 | -49.0 | 85.0 | NA | NA | |||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:175 | B:175 | 62.0 | NA | T | 68.6 | -21.5 | 62.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 61.0 | NA | T | 68.7 | -21.6 | 61.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:175 | B:175 | 62.0 | NA | T | 68.6 | -21.4 | 62.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 62.0 | NA | T | 68.7 | -21.6 | 62.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:175 | B:175 | 67.0 | NA | T | 63.9 | -6.6 | 67.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 68.0 | NA | T | 60.6 | -0.9 | 68.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:175 | B:175 | 67.0 | NA | T | 63.9 | -6.7 | 67.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 67.0 | NA | T | 58.2 | 5.1 | 67.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:175 | B:175 | 67.0 | NA | T | 62.0 | -0.7 | 67.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 69.0 | NA | T | 55.9 | 11.1 | 69.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | GLN | B:175 | B:175 | 69.0 | NA | T | 57.9 | 5.3 | 69.0 | NA | NA | ||||||
GLN | D:175 | D:175 | 70.0 | NA | T | 55.8 | 11.1 | 70.0 | NA | NA | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLN | B:156 | B:175 | 81.0 | 0.45 | H | -70.4 | -45.2 | 81.0 | 0.45 | 0.0 | ||||||
GLN | D:156 | D:175 | 81.0 | 0.45 | H | -67.8 | -42.8 | 81.0 | 0.45 | 0.0 | |||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | GLN | B:156 | B:175 | 28.0 | NA | T | 68.6 | -21.4 | 28.0 | NA | NA | ||||||
GLN | D:156 | D:175 | 35.0 | NA | T | 68.7 | -21.6 | 35.0 | NA | NA | |||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLN | B:150 | B:180 | 116.0 | 0.644 | H | -67.1 | -45.7 | 109.0 | 0.606 | 0.038 |
A:Q91977:0.039 |
HOH |
3.331 |
N |
O |
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GLN | D:150 | D:180 | 113.0 | 0.628 | H | -66.9 | -46.1 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLN | B:150 | B:180 | 92.0 | 0.511 | H | -68.4 | -40.8 | 92.0 | 0.511 | 0.0 |
HOH |
3.005 |
N |
O |
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GLN | D:150 | D:180 | 110.0 | 0.611 | H | -68.9 | -40.9 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | GLN | B:150 | B:180 | 113.0 | 0.628 | H | -59.4 | -40.9 | 102.0 | 0.567 | 0.061 |
A:Q91977:0.061 |
HOH |
3.094 |
N |
O |
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GLN | D:150 | D:180 | 113.0 | 0.628 | H | -59.3 | -40.9 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLN | B:150 | B:180 | 108.0 | 0.6 | H | -73.2 | -44.4 | 100.0 | 0.556 | 0.044 |
A:Q91977:0.044 |
HOH |
6.769 |
N |
O |
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GLN | D:150 | D:180 | 108.0 | 0.6 | H | -72.5 | -37.8 | 108.0 | 0.6 | 0.0 |
HOH |
3.380 |
N |
O |
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3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | GLN | B:150 | B:180 | 111.0 | 0.617 | H | -75.6 | -42.4 | 99.0 | 0.55 | 0.067 |
A:Q91977:0.067 |
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GLN | D:150 | D:180 | 44.0 | NA | H | -79.2 | -29.3 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | GLN | C:150 | C:180 | 53.0 | NA | H | -68.3 | -44.3 | 53.0 | NA | NA | ||||||
GLN | E:150 | D:180 | 122.0 | 0.678 | H | -73.3 | -34.7 | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLN | A:149 | A:180 | 108.0 | 0.6 | H | -68.1 | -41.4 | 108.0 | 0.6 | 0.0 |
CL CL CL HOH |
3.355 2.985 8.606 4.563 |
N CG C O |
CL CL CL O |
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3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | GLN | A:149 | A:180 | 48.0 | NA | H | -60.9 | -46.5 | 48.0 | NA | NA |
CL |
3.246 |
CB |
CL |
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6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 115.0 | 0.639 | H | -70.3 | -43.9 | 109.0 | 0.606 | 0.033 |
A:A0A1L8F5J9:0.033 |
HOH |
3.083 |
N |
O |
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GLN | D:149 | D:180 | 109.0 | 0.606 | H | -71.9 | -40.9 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 115.0 | 0.639 | H | -72.8 | -43.7 | 103.0 | 0.572 | 0.067 |
A:A0A1L8F5J9:0.067 |
HOH |
3.816 |
NE2 |
O |
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GLN | D:149 | D:180 | 113.0 | 0.628 | H | -74.3 | -45.9 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 113.0 | 0.628 | H | -69.0 | -44.0 | 103.0 | 0.572 | 0.056 |
A:A0A1L8F5J9:0.056 |
HOH |
3.020 |
NE2 |
O |
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GLN | D:149 | D:180 | 113.0 | 0.628 | H | -74.9 | -40.5 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 117.0 | 0.65 | H | -77.6 | -44.1 | 108.0 | 0.6 | 0.05 |
A:A0A1L8F5J9:0.05 |
HOH |
3.027 |
N |
O |
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GLN | D:149 | D:180 | 109.0 | 0.606 | H | -79.4 | -42.6 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 116.0 | 0.644 | H | -71.8 | -43.6 | 104.0 | 0.578 | 0.066 |
A:A0A1L8F5J9:0.067 |
HOH |
3.302 |
N |
O |
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GLN | D:149 | D:180 | 114.0 | 0.633 | H | -72.7 | -43.5 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 115.0 | 0.639 | H | -72.9 | -46.6 | 105.0 | 0.583 | 0.056 |
A:A0A1L8F5J9:0.056 |
HOH |
3.088 |
N |
O |
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GLN | D:149 | D:180 | 117.0 | 0.65 | H | -69.9 | -49.8 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | GLN | B:149 | B:180 | 112.0 | 0.622 | H | -68.0 | -46.2 | 100.0 | 0.556 | 0.066 |
A:A0A1L8F5J9:0.067 |
HOH |
3.424 |
N |
O |
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GLN | D:149 | D:180 | 117.0 | 0.65 | H | -69.1 | -42.5 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | GLN | B:149 | D:180 | 41.0 | NA | H | -60.6 | -50.9 | 41.0 | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | GLN | A:180 | A:180 | 107.0 | 0.594 | H | -68.0 | -44.1 |