Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 13906759 | . | T | A | CCDS8662.1:NM_000834.3:c.502Atc>Ttc_NP_000825.2:p.168I>F | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | ILE | B:168 | B:168 | 19.0 | 0.109 | -71.6 | -63.5 | 19.0 | 0.109 | 0.0 | |||||||
ILE | D:168 | D:168 | 18.0 | 0.103 | -71.1 | -62.7 | 18.0 | 0.103 | 0.0 | ||||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | ILE | B:199 | B:168 | 1.0 | 0.006 | -78.3 | 86.2 | 1.0 | 0.006 | 0.0 | |||||||
ILE | D:199 | D:168 | 1.0 | 0.006 | -78.2 | 86.2 | 1.0 | 0.006 | 0.0 | ||||||||||||||
5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ILE | B:143 | B:168 | 66.0 | NA | S | -77.6 | 156.7 | 66.0 | NA | NA | ||||||
ILE | D:143 | D:168 | 67.0 | NA | S | -77.6 | 156.7 | 67.0 | NA | NA | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ILE | B:143 | B:168 | 49.0 | NA | -98.2 | 129.1 | 49.0 | NA | NA | |||||||
ILE | D:143 | D:168 | 49.0 | NA | -98.2 | 129.1 | 49.0 | NA | NA | ||||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ILE | B:143 | B:168 | 32.0 | NA | -74.2 | 139.9 | 32.0 | NA | NA | |||||||
ILE | D:143 | D:168 | 32.0 | NA | -74.1 | 139.9 | 32.0 | NA | NA | ||||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | ILE | B:143 | B:168 | 27.0 | NA | E | -71.6 | 127.0 | 27.0 | NA | NA | ||||||
ILE | D:143 | D:168 | 27.0 | NA | -71.6 | 126.9 | 27.0 | NA | NA | ||||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | ILE | B:143 | B:168 | 35.0 | NA | E | -101.1 | 110.7 | 35.0 | NA | NA | ||||||
ILE | D:143 | D:168 | 36.0 | NA | E | -101.1 | 110.6 | 36.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ILE | B:199 | B:168 | 69.0 | 0.394 | -137.1 | 138.7 | 69.0 | 0.394 | 0.0 | |||||||
ILE | D:199 | D:168 | 68.0 | 0.389 | -137.1 | 138.7 | 68.0 | 0.389 | 0.0 | ||||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ILE | B:199 | B:168 | 77.0 | 0.44 | E | -130.7 | 134.0 | 77.0 | 0.44 | 0.0 | ||||||
ILE | D:199 | D:168 | 76.0 | 0.434 | E | -130.7 | 134.0 | 76.0 | 0.434 | 0.0 | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ILE | B:199 | B:168 | 22.0 | 0.126 | -61.3 | -68.8 | 22.0 | 0.126 | 0.0 | |||||||
ILE | D:199 | D:168 | 22.0 | 0.126 | -61.3 | -68.8 | 22.0 | 0.126 | 0.0 | ||||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ILE | B:199 | B:168 | 47.0 | 0.269 | -169.4 | 139.7 | 47.0 | 0.269 | 0.0 | |||||||
ILE | D:199 | D:168 | 48.0 | 0.274 | -169.4 | 139.7 | 48.0 | 0.274 | 0.0 | ||||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | ILE | B:199 | B:168 | 1.0 | 0.006 | -54.7 | 150.2 | 1.0 | 0.006 | 0.0 | |||||||
ILE | D:199 | D:168 | 0.0 | 0.0 | -51.6 | 140.3 | 0.0 | 0.0 | 0.0 | ||||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | ILE | B:199 | B:168 | 68.0 | 0.389 | -131.4 | 97.0 | 68.0 | 0.389 | 0.0 | |||||||
ILE | D:199 | D:168 | 68.0 | 0.389 | -131.4 | 97.1 | 68.0 | 0.389 | 0.0 | ||||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | ILE | B:199 | B:168 | 79.0 | 0.451 | -64.8 | 159.4 | 79.0 | 0.451 | 0.0 | |||||||
ILE | D:199 | D:168 | 0.0 | 0.0 | -43.7 | 137.8 | 0.0 | 0.0 | 0.0 | ||||||||||||||
6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | ILE | B:199 | B:168 | 22.0 | NA | E | -111.8 | 157.6 | 22.0 | NA | NA | ||||||
ILE | D:199 | D:168 | 22.0 | NA | E | -111.8 | 157.6 | 22.0 | NA | NA | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | ILE | B:199 | B:168 | 76.0 | 0.434 | E | -138.7 | 117.1 | 76.0 | 0.434 | 0.0 | ||||||
ILE | D:199 | D:168 | 77.0 | 0.44 | E | -138.8 | 117.1 | 77.0 | 0.44 | 0.0 | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | ILE | B:142 | B:168 | 94.0 | 0.537 | E | -92.3 | 118.0 | 94.0 | 0.537 | 0.0 | ||||||
ILE | D:142 | D:168 | 96.0 | 0.549 | E | -104.1 | 121.8 | 96.0 | 0.549 | 0.0 | |||||||||||||
6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | ILE | B:135 | B:168 | 96.0 | 0.549 | E | -101.4 | 108.1 | 96.0 | 0.549 | 0.0 | ||||||
ILE | D:135 | D:168 | 95.0 | 0.543 | E | -101.4 | 108.1 | 95.0 | 0.543 | 0.0 | |||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | ILE | D:163 | D:163 | 81.0 | 0.463 | E | -102.0 | 126.6 | 81.0 | 0.463 | 0.0 | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | ILE | D:163 | D:163 | 81.0 | 0.463 | E | -102.0 | 126.7 | 81.0 | 0.463 | 0.0 | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | C:163 | B:163 | 52.0 | NA | E | -91.6 | 111.5 | 52.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 48.0 | NA | E | -84.4 | 129.0 | 48.0 | NA | NA | |||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | C:163 | B:163 | 55.0 | NA | E | -72.5 | 123.9 | 55.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 51.0 | NA | E | -81.9 | 129.0 | 51.0 | NA | NA | |||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | B:163 | B:163 | 48.0 | NA | E | -102.4 | 126.8 | 48.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 50.0 | NA | E | -102.0 | 126.7 | 50.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | B:163 | B:163 | 49.0 | NA | E | -102.5 | 126.8 | 49.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 49.0 | NA | E | -102.0 | 126.7 | 49.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | B:163 | B:163 | 50.0 | NA | E | -102.5 | 126.9 | 50.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 48.0 | NA | E | -102.0 | 126.8 | 48.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | B:163 | B:163 | 62.0 | NA | -102.5 | 126.8 | 62.0 | NA | NA | |||||||
ILE | D:163 | D:163 | 49.0 | NA | E | -102.0 | 126.7 | 49.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | B:163 | B:163 | 49.0 | NA | E | -102.6 | 126.8 | 49.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 50.0 | NA | E | -102.0 | 126.7 | 50.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | ILE | B:163 | B:163 | 49.0 | NA | E | -102.1 | 126.6 | 49.0 | NA | NA | ||||||
ILE | D:163 | D:163 | 48.0 | NA | E | -102.2 | 126.6 | 48.0 | NA | NA | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | ILE | B:144 | B:163 | 49.0 | 0.28 | E | -84.2 | 121.7 | 49.0 | 0.28 | 0.0 | ||||||
ILE | D:144 | D:163 | 78.0 | 0.446 | E | -84.1 | 121.8 | 78.0 | 0.446 | 0.0 | |||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | ILE | B:144 | B:163 | 86.0 | 0.491 | E | -102.4 | 126.8 | 86.0 | 0.491 | 0.0 | ||||||
ILE | D:144 | D:163 | 83.0 | 0.474 | E | -102.1 | 126.7 | 83.0 | 0.474 | 0.0 | |||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ILE | B:138 | B:168 | 80.0 | 0.457 | E | -103.0 | 118.9 | 80.0 | 0.457 | 0.0 |
HOH |
2.875 |
O |
O |
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ILE | D:138 | D:168 | 81.0 | 0.463 | E | -103.2 | 119.2 | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ILE | B:138 | B:168 | 80.0 | 0.457 | E | -102.0 | 119.6 | 80.0 | 0.457 | 0.0 |
HOH |
2.902 |
O |
O |
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ILE | D:138 | D:168 | 82.0 | 0.469 | E | -101.7 | 120.5 | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | ILE | B:138 | B:168 | 80.0 | 0.457 | E | -94.0 | 117.5 | 80.0 | 0.457 | 0.0 |
HOH |
2.754 |
O |
O |
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ILE | D:138 | D:168 | 78.0 | 0.446 | E | -94.6 | 118.1 | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | ILE | B:138 | B:168 | 79.0 | 0.451 | E | -103.9 | 122.1 | 79.0 | 0.451 | 0.0 |
HOH |
7.174 |
CG2 |
O |
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ILE | D:138 | D:168 | 76.0 | 0.434 | E | -123.4 | 121.9 | 76.0 | 0.434 | 0.0 |
HOH |
2.725 |
N |
O |
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3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | ILE | B:138 | B:168 | 89.0 | 0.509 | E | -115.6 | 120.1 | 89.0 | 0.509 | 0.0 | ||||||
ILE | D:138 | D:168 | 90.0 | 0.514 | E | -129.3 | 119.1 | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | ILE | C:138 | C:168 | 33.0 | NA | E | -121.8 | 117.2 | 33.0 | NA | NA | ||||||
ILE | E:138 | D:168 | 41.0 | NA | E | -122.1 | 117.2 | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | ILE | A:137 | A:168 | 57.0 | 0.326 | E | -99.6 | 120.7 | 57.0 | 0.326 | 0.0 | ||||||
3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | ILE | A:137 | A:168 | 37.0 | NA | E | -102.6 | 117.7 | 37.0 | NA | NA | ||||||
6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 58.0 | 0.331 | E | -121.4 | 117.5 | 58.0 | 0.331 | 0.0 |
HOH |
7.174 |
CG2 |
O |
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ILE | D:137 | D:168 | 79.0 | 0.451 | E | -117.9 | 114.2 | NA | NA | NA | |||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 65.0 | 0.371 | E | -112.1 | 121.9 | 65.0 | 0.371 | 0.0 |
HOH |
7.121 |
CG2 |
O |
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ILE | D:137 | D:168 | 82.0 | 0.469 | E | -119.0 | 117.7 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 77.0 | 0.44 | E | -114.0 | 122.6 | 77.0 | 0.44 | 0.0 |
HOH |
2.951 |
O |
O |
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ILE | D:137 | D:168 | 77.0 | 0.44 | E | -115.8 | 121.2 | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 64.0 | 0.366 | E | -97.8 | 126.7 | 64.0 | 0.366 | 0.0 |
HOH |
6.768 |
CG2 |
O |
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ILE | D:137 | D:168 | 79.0 | 0.451 | E | -112.6 | 119.1 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 60.0 | 0.343 | E | -108.3 | 122.7 | 60.0 | 0.343 | 0.0 |
HOH |
6.390 |
N |
O |
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ILE | D:137 | D:168 | 77.0 | 0.44 | E | -112.0 | 121.7 | NA | NA | NA | |||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 77.0 | 0.44 | E | -123.0 | 120.1 | 77.0 | 0.44 | 0.0 |
HOH |
7.957 |
CA |
O |
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ILE | D:137 | D:168 | 78.0 | 0.446 | E | -122.7 | 120.9 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | ILE | B:137 | B:168 | 62.0 | 0.354 | E | -113.9 | 120.4 | 62.0 | 0.354 | 0.0 |
HOH |
6.581 |
N |
O |
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ILE | D:137 | D:168 | 79.0 | 0.451 | E | -114.1 | 120.1 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | ILE | B:137 | D:168 | 36.0 | NA | E | -119.4 | 113.8 | 36.0 | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | ILE | A:168 | A:168 | 65.0 | 0.371 | E | -105.1 | 116.6 |