Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 14018982 | . | T | A | CCDS8662.1:NM_000834.3:c.161cAc>cTc_NP_000825.2:p.54H>L | Homo sapiens glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7eu8 | 2 | Q13224 | 100.0 | 0.0 |
EM |
2021-07-28 | HIS | B:54 | B:54 | 38.0 | NA | H | -63.8 | -42.2 | 38.0 | NA | NA | ||||||
HIS | D:54 | D:54 | 69.0 | 0.354 | T | -73.6 | -15.2 | 69.0 | 0.354 | 0.0 | |||||||||||||
6wi1 | 2 | ? | 99.28 | 0.0 |
EM |
2020-07-15 | HIS | B:85 | B:54 | 75.0 | NA | G | -64.7 | -14.1 | 75.0 | NA | NA | ||||||
HIS | D:85 | D:54 | 78.0 | NA | G | -64.8 | -14.1 | 78.0 | NA | NA | |||||||||||||
5fxg | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | HIS | B:29 | B:54 | 28.0 | NA | H | -61.8 | -26.9 | 28.0 | NA | NA | ||||||
HIS | D:29 | D:54 | 27.0 | NA | H | -61.8 | -26.8 | 27.0 | NA | NA | |||||||||||||
5fxh | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | HIS | B:29 | B:54 | 43.0 | NA | H | -55.8 | -41.8 | 43.0 | NA | NA | ||||||
HIS | D:29 | D:54 | 44.0 | NA | H | -55.7 | -41.8 | 44.0 | NA | NA | |||||||||||||
5fxi | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | HIS | B:29 | B:54 | 53.0 | NA | H | -55.2 | -42.5 | 53.0 | NA | NA | ||||||
HIS | D:29 | D:54 | 54.0 | NA | H | -55.2 | -42.5 | 54.0 | NA | NA | |||||||||||||
5fxj | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-25 | HIS | B:29 | B:54 | 34.0 | NA | T | -63.2 | -60.7 | 34.0 | NA | NA | ||||||
HIS | D:29 | D:54 | 34.0 | NA | T | -63.2 | -60.7 | 34.0 | NA | NA | |||||||||||||
5fxk | 2 | Q00960 | 98.91 | 0.0 |
EM |
2016-05-11 | HIS | B:29 | B:54 | 44.0 | NA | T | -132.1 | -67.7 | 44.0 | NA | NA | ||||||
HIS | D:29 | D:54 | 45.0 | NA | T | -132.1 | -67.7 | 45.0 | NA | NA | |||||||||||||
6whr | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | HIS | B:85 | B:54 | 38.0 | NA | H | -68.3 | -35.0 | 38.0 | NA | NA | ||||||
HIS | D:85 | D:54 | 37.0 | NA | H | -68.4 | -35.0 | 37.0 | NA | NA | |||||||||||||
6whs | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | HIS | B:85 | B:54 | 43.0 | NA | T | -52.8 | -39.4 | 43.0 | NA | NA | ||||||
HIS | D:85 | D:54 | 41.0 | NA | T | -52.8 | -39.4 | 41.0 | NA | NA | |||||||||||||
6wht | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | HIS | B:85 | B:54 | 58.0 | 0.297 | H | -60.6 | -30.2 | 58.0 | 0.297 | 0.0 | ||||||
HIS | D:85 | D:54 | 56.0 | 0.287 | H | -60.6 | -30.1 | 56.0 | 0.287 | 0.0 | |||||||||||||
6whu | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | HIS | B:85 | B:54 | 157.0 | 0.805 | T | -64.7 | -9.9 | 157.0 | 0.805 | 0.0 | ||||||
HIS | D:85 | D:54 | 158.0 | 0.81 | T | -64.6 | -9.8 | 158.0 | 0.81 | 0.0 | |||||||||||||
6whv | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-08-05 | HIS | B:85 | B:54 | 96.0 | NA | -72.9 | 94.7 | 96.0 | NA | NA | |||||||
HIS | D:85 | D:54 | 49.0 | NA | H | -61.2 | -29.5 | 49.0 | NA | NA | |||||||||||||
6whw | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | HIS | B:85 | B:54 | 128.0 | 0.656 | G | -85.1 | 19.7 | 128.0 | 0.656 | 0.0 | ||||||
HIS | D:85 | D:54 | 125.0 | 0.641 | G | -85.1 | 19.7 | 125.0 | 0.641 | 0.0 | |||||||||||||
6whx | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | HIS | B:85 | B:54 | 31.0 | NA | S | -81.0 | -64.0 | 31.0 | NA | NA | ||||||
HIS | D:85 | D:54 | 93.0 | NA | T | -118.5 | 19.3 | 93.0 | NA | NA | |||||||||||||
6why | 2 | ? | 98.91 | 0.0 |
EM |
2020-07-15 | HIS | B:85 | B:54 | 40.0 | NA | H | -59.1 | -41.6 | 40.0 | NA | NA | ||||||
HIS | D:85 | D:54 | 38.0 | NA | H | -59.2 | -41.6 | 38.0 | NA | NA | |||||||||||||
6wi0 | 2 | Q00960 | 98.91 | 0.0 |
EM |
2020-07-15 | HIS | B:85 | B:54 | 50.0 | NA | G | -87.1 | 21.7 | 50.0 | NA | NA | ||||||
HIS | D:85 | D:54 | 51.0 | NA | G | -87.1 | 21.7 | 51.0 | NA | NA | |||||||||||||
4pe5 | 2 | Q00960 | 97.82 | 0.0 |
X-RAY |
2014-06-04 | HIS | B:28 | B:54 | 16.0 | NA | T | -125.7 | -6.5 | 16.0 | NA | NA | ||||||
HIS | D:28 | D:54 | 26.0 | NA | H | -130.6 | -25.4 | 26.0 | NA | NA | |||||||||||||
6cna | 2 | Q00960 | 99.14 | 0.0 |
EM |
2018-10-03 | HIS | B:21 | B:54 | 18.0 | NA | H | -65.2 | -46.1 | 18.0 | NA | NA | ||||||
HIS | D:21 | D:54 | 18.0 | NA | H | -65.2 | -46.1 | 18.0 | NA | NA | |||||||||||||
5uow | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | HIS | D:49 | D:49 | 16.0 | NA | H | -63.0 | -41.7 | 16.0 | NA | NA | ||||||
5up2 | 3 | A7XY94 | 86.86 | 0.0 |
EM |
2017-03-22 | HIS | D:49 | D:49 | 16.0 | NA | H | -63.0 | -41.7 | 16.0 | NA | NA | ||||||
5iou | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | C:49 | B:49 | 109.0 | NA | -108.0 | 17.4 | 109.0 | NA | NA | |||||||
HIS | D:49 | D:49 | 108.0 | NA | -107.8 | 19.0 | 108.0 | NA | NA | ||||||||||||||
5iov | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | C:49 | B:49 | 105.0 | NA | -107.6 | 20.1 | 105.0 | NA | NA | |||||||
HIS | D:49 | D:49 | 108.0 | NA | -108.3 | 19.5 | 108.0 | NA | NA | ||||||||||||||
5ipq | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | B:49 | B:49 | 62.0 | NA | S | -109.3 | -162.1 | 62.0 | NA | NA | ||||||
HIS | D:49 | D:49 | 27.0 | NA | H | -58.2 | -60.0 | 27.0 | NA | NA | |||||||||||||
5ipr | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | B:49 | B:49 | 60.0 | NA | S | -109.2 | -162.1 | 60.0 | NA | NA | ||||||
HIS | D:49 | D:49 | 28.0 | NA | H | -58.2 | -60.0 | 28.0 | NA | NA | |||||||||||||
5ips | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | B:49 | B:49 | 59.0 | NA | S | -109.2 | -162.1 | 59.0 | NA | NA | ||||||
HIS | D:49 | D:49 | 27.0 | NA | H | -58.2 | -60.0 | 27.0 | NA | NA | |||||||||||||
5ipt | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | B:49 | B:49 | 62.0 | NA | S | -109.3 | -162.2 | 62.0 | NA | NA | ||||||
HIS | D:49 | D:49 | 28.0 | NA | H | -58.2 | -60.1 | 28.0 | NA | NA | |||||||||||||
5ipu | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | B:49 | B:49 | 60.0 | NA | S | -109.3 | -162.1 | 60.0 | NA | NA | ||||||
HIS | D:49 | D:49 | 28.0 | NA | H | -58.2 | -60.0 | 28.0 | NA | NA | |||||||||||||
5ipv | 2 | A7XY94 | 85.78 | 0.0 |
EM |
2016-04-20 | HIS | B:49 | B:49 | 28.0 | NA | H | -58.2 | -60.0 | 28.0 | NA | NA | ||||||
HIS | D:49 | D:49 | 27.0 | NA | H | -58.2 | -59.9 | 27.0 | NA | NA | |||||||||||||
4tll | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | HIS | B:30 | B:49 | 48.0 | NA | 53.9 | -143.9 | 48.0 | NA | NA | |||||||
HIS | D:30 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
4tlm | 2 | A7XY94 | 87.47 | 0.0 |
X-RAY |
2014-07-02 | HIS | B:30 | B:49 | 59.0 | 0.303 | S | -109.3 | -162.1 | 59.0 | 0.303 | 0.0 | ||||||
HIS | D:30 | D:49 | 17.0 | NA | H | -58.2 | -60.0 | 17.0 | NA | NA | |||||||||||||
5ewj | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | HIS | B:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
HIS | D:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
5ewl | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | HIS | B:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
HIS | D:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
5ewm | 2 | Q13224 | 99.73 | 0.0 |
X-RAY |
2016-03-02 | HIS | B:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
HIS | D:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
3qel | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | HIS | B:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
HIS | D:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
3qem | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2011-06-15 | HIS | B:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
HIS | D:24 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
5b3j | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-05-11 | HIS | C:24 | C:54 | 19.0 | 0.097 | H | -77.6 | -33.6 | 19.0 | 0.097 | 0.0 |
HOH |
9.842 |
CE1 |
O |
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HIS | E:24 | D:54 | 21.0 | 0.108 | H | -77.0 | -35.5 | NA | NA | NA | |||||||||||||
3jpw | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | HIS | A:23 | A:54 | 170.0 | 0.872 | G | -54.4 | -17.3 | 170.0 | 0.872 | 0.0 | ||||||
3jpy | 1 | Q00960 | 99.45 | 0.0 |
X-RAY |
2009-12-08 | HIS | A:23 | A:54 | 157.0 | 0.805 | S | -87.2 | -81.0 | 157.0 | 0.805 | 0.0 | ||||||
6e7r | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 36.0 | 0.185 | T | -94.4 | 16.6 | 36.0 | 0.185 | 0.0 | ||||||
HIS | D:23 | D:54 | 84.0 | 0.431 | -96.8 | 360.0 | NA | NA | NA | ||||||||||||||
6e7s | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 27.0 | 0.138 | T | -83.3 | 20.0 | 27.0 | 0.138 | 0.0 | ||||||
HIS | D:23 | D:54 | 33.0 | 0.169 | H | -65.2 | -13.1 | NA | NA | NA | |||||||||||||
6e7t | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 104.0 | 0.533 | -91.1 | 360.0 | 104.0 | 0.533 | 0.0 | |||||||
HIS | D:23 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6e7u | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 71.0 | 0.364 | -98.2 | 360.0 | 71.0 | 0.364 | 0.0 | |||||||
HIS | D:23 | D:54 | 53.0 | 0.272 | H | -97.8 | -19.4 | NA | NA | NA | |||||||||||||
6e7v | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 54.0 | 0.277 | -105.5 | 360.0 | 54.0 | 0.277 | 0.0 | |||||||
HIS | D:23 | D:54 | 105.0 | 0.538 | -109.8 | 360.0 | NA | NA | NA | ||||||||||||||
6e7w | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 85.0 | NA | -119.3 | 360.0 | 85.0 | NA | NA | |||||||
HIS | D:23 | D:54 | 30.0 | NA | S | -101.1 | 4.0 | NA | NA | NA | |||||||||||||
6e7x | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2019-01-30 | HIS | B:23 | B:54 | 34.0 | 0.174 | T | -96.8 | 12.8 | 34.0 | 0.174 | 0.0 | ||||||
HIS | D:23 | D:54 | 26.0 | 0.133 | H | -95.6 | -11.5 | NA | NA | NA | |||||||||||||
5tpz | 2 | Q00960 | 99.45 | 0.0 |
X-RAY |
2016-12-14 | HIS | B:23 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q13224-f1 | 1 | Q13224 | 100.0 | 0.0 | HIS | A:54 | A:54 | 55.0 | 0.282 | -120.1 | 62.8 |