Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50452838 . G A CCDS8796.1:NM_020039.3:c.289Gag>Aag_NP_064423.2:p.97E>K Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 GLU B:97 D:97 60.0 0.316 S -60.7 -45.8 60.0 0.316 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 GLU A:98 A:98 68.0 0.358 S -79.6 -37.1 68.0 0.358 0.0
GLU B:98 B:98 69.0 0.363 S -79.6 -37.2 69.0 0.363 0.0
GLU C:98 C:98 68.0 0.358 S -79.6 -37.1 68.0 0.358 0.0
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 GLU A:98 A:98 10.0 0.053 S -97.9 -32.2 10.0 0.053 0.0
GLU B:98 C:98 11.0 0.058 S -97.8 -32.3 11.0 0.058 0.0
GLU C:98 B:98 12.0 0.063 S -97.8 -32.2 12.0 0.063 0.0
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 GLU A:98 A:98 51.0 0.268 S -76.9 -44.7 51.0 0.268 0.0
GLU B:98 C:98 51.0 0.268 S -76.9 -44.8 51.0 0.268 0.0
GLU C:98 B:98 49.0 0.258 S -77.0 -44.7 49.0 0.258 0.0
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 GLU A:106 A:97 66.0 0.347 S -79.4 -39.0 66.0 0.347 0.0
GLU B:106 B:97 66.0 0.347 S -79.4 -39.0 66.0 0.347 0.0
GLU C:106 C:97 64.0 0.337 S -79.4 -39.0 64.0 0.337 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 GLU A:106 A:97 37.0 0.195 S -91.8 -40.5 37.0 0.195 0.0
GLU B:106 B:97 37.0 0.195 S -91.8 -40.5 37.0 0.195 0.0
GLU C:106 C:97 39.0 0.205 S -91.7 -40.6 39.0 0.205 0.0
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 GLU A:87 A:97 44.0 0.232 S -74.6 -39.3 44.0 0.232 0.0 HOH
 9.593
 OE2
 O
GLU B:87 B:97 40.0 0.211 S -73.2 -39.4 40.0 0.211 0.0
GLU C:87 C:97 46.0 0.242 S -73.6 -39.2 46.0 0.242 0.0 HOH
 9.657
 OE2
 O
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 GLU A:87 A:97 13.0 0.068 -87.3 -31.3 13.0 0.068 0.0
GLU B:87 B:97 12.0 0.063 -87.6 -31.3 12.0 0.063 0.0
GLU C:87 C:97 13.0 0.068 -86.4 -32.9 13.0 0.068 0.0 CL
 4.447
 O
 CL
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 GLU A:102 A:98 14.0 0.074 -76.5 -37.6 14.0 0.074 0.0 HOH
 2.165
 O
 O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 GLU A:97 A:98 12.0 0.063 -82.0 -38.8 12.0 0.063 0.0 CS
HOH
 6.527
2.461
 OE2
O
 CS
O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 GLU A:85 A:98 16.0 0.084 -79.2 -36.4 10.0 0.053 0.031 E:P60514:0.032
 HOH
 2.910
 O
 O
GLU B:85 B:98 17.0 0.089 -78.4 -37.1 12.0 0.063 0.026 F:P60514:0.026
 HOH
 2.789
 N
 O
GLU C:85 C:98 16.0 0.084 -79.7 -38.2 11.0 0.058 0.026 D:P60514:0.026
 HOH
 2.884
 N
 O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 GLU A:85 A:98 16.0 0.084 -71.7 -37.3 16.0 0.084 0.0
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLU A:85 A:98 14.0 0.074 -84.8 -38.9 14.0 0.074 0.0 NA
P6G
HOH
 7.689
3.189
2.707
 OE1
OE1
O
 NA
C17
O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLU A:85 A:98 14.0 0.074 -84.2 -31.6 14.0 0.074 0.0 NA
P6G
HOH
 7.056
3.058
2.685
 OE1
OE1
O
 NA
C17
O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLU A:85 A:98 14.0 0.074 -82.8 -32.7 14.0 0.074 0.0 CS
PE4
HOH
 6.779
3.215
2.860
 OE1
OE1
O
 CS
C1
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 GLU A:85 A:98 10.0 0.053 -76.5 -37.0 10.0 0.053 0.0
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 GLU A:74 A:98 75.0 0.395 S -67.1 -44.0 75.0 0.395 0.0
GLU B:74 C:98 66.0 0.347 -66.5 -44.0 66.0 0.347 0.0
GLU C:74 B:98 33.0 NA S -66.9 -43.7 33.0 NA NA
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 GLU A:74 A:98 69.0 0.363 -67.0 -43.8 69.0 0.363 0.0
GLU B:74 C:98 79.0 0.416 S -66.5 -44.0 79.0 0.416 0.0
GLU C:74 B:98 32.0 NA S -66.4 -43.6 32.0 NA NA
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 GLU A:74 A:98 74.0 0.389 S -67.1 -44.0 74.0 0.389 0.0
GLU B:74 C:98 67.0 0.353 -66.5 -43.9 67.0 0.353 0.0
GLU C:74 B:98 33.0 NA S -67.0 -43.6 33.0 NA NA
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 GLU A:74 A:98 75.0 0.395 S -67.1 -44.0 75.0 0.395 0.0
GLU B:74 C:98 66.0 0.347 -66.4 -44.0 66.0 0.347 0.0
GLU C:74 B:98 33.0 NA S -66.9 -43.7 33.0 NA NA
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 GLU A:73 A:98 16.0 0.084 -81.8 -36.0 16.0 0.084 0.0 HOH
 2.682
 O
 O
GLU B:73 B:98 16.0 0.084 -83.0 -31.0 16.0 0.084 0.0 HOH
 2.589
 O
 O
GLU C:73 C:98 14.0 0.074 -82.4 -32.0 14.0 0.074 0.0 HOH
 2.729
 O
 O
GLU D:73 D:98 15.0 0.079 -86.5 -30.8 NA NA NA
GLU E:73 E:98 13.0 0.068 -85.7 -31.2 NA NA NA
GLU F:73 F:98 13.0 0.068 -84.4 -28.7 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 GLU A:73 A:98 57.0 0.3 S -90.3 -44.0 57.0 0.3 0.0 UZG
 2.897
 OE2
 N19
GLU B:73 B:98 49.0 0.258 -90.6 -43.3 49.0 0.258 0.0 UZG
 2.769
 OE2
 N19
GLU C:73 C:98 45.0 0.237 -91.1 -43.1 45.0 0.237 0.0 UZG
 2.652
 OE1
 N19
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 GLU A:94 A:98 12.0 0.063 -90.2 -29.2 12.0 0.063 0.0 HOH
 2.924
 O
 O
GLU B:94 B:98 11.0 0.058 -90.4 -29.3 11.0 0.058 0.0 HOH
 5.468
 OE2
 O
GLU C:94 C:98 12.0 0.063 -90.4 -29.6 12.0 0.063 0.0 HOH
 2.811
 OE2
 O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 GLU A:94 A:98 12.0 0.063 -87.2 -46.2 12.0 0.063 0.0
GLU B:94 B:98 15.0 0.079 -86.8 -46.5 15.0 0.079 0.0
GLU C:94 C:98 15.0 0.079 -87.2 -46.5 15.0 0.079 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 GLU A:97 A:97 14.0 0.074 -74.1 -37.7