Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 50453627 | . | A | C | CCDS8796.1:NM_020039.3:c.448Aaa>Caa_NP_064423.2:p.150K>Q | Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA. |
---|---|---|---|---|---|---|---|
|
|
|
|
PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7rnn | 2 | P78348 | 91.46 | 0.0 |
EM |
2021-08-11 | LYS | B:150 | D:150 | 46.0 | NA | -101.5 | 162.7 | 46.0 | NA | NA | |||||||
6ave | 1 | Q1XA76 | 82.06 | 0.0 |
EM |
2018-03-21 | LYS | A:151 | A:151 | 26.0 | NA | -133.9 | 137.9 | 26.0 | NA | NA | |||||||
LYS | B:151 | B:151 | 26.0 | NA | -133.9 | 137.9 | 26.0 | NA | NA | ||||||||||||||
LYS | C:151 | C:151 | 27.0 | NA | -133.9 | 137.9 | 27.0 | NA | NA | ||||||||||||||
6vtk | 1 | Q1XA76 | 82.06 | 0.0 |
EM |
2020-03-11 | LYS | A:151 | A:151 | 115.0 | 0.575 | -104.5 | 158.2 | 115.0 | 0.575 | 0.0 | |||||||
LYS | B:151 | C:151 | 116.0 | 0.58 | -104.5 | 158.2 | 116.0 | 0.58 | 0.0 | ||||||||||||||
LYS | C:151 | B:151 | 116.0 | 0.58 | -104.5 | 158.2 | 116.0 | 0.58 | 0.0 | ||||||||||||||
6vtl | 1 | Q1XA76 | 82.06 | 0.0 |
EM |
2020-03-11 | LYS | A:151 | A:151 | 45.0 | NA | -113.1 | 155.7 | 45.0 | NA | NA | |||||||
LYS | B:151 | C:151 | 45.0 | NA | -113.1 | 155.7 | 45.0 | NA | NA | ||||||||||||||
LYS | C:151 | B:151 | 45.0 | NA | -113.1 | 155.7 | 45.0 | NA | NA | ||||||||||||||
7cfs | 1 | P78348 | 91.05 | 0.0 |
EM |
2020-10-21 | LYS | A:159 | A:150 | 52.0 | NA | -72.7 | 164.2 | 52.0 | NA | NA | |||||||
LYS | B:159 | B:150 | 50.0 | NA | -72.7 | 164.2 | 50.0 | NA | NA | ||||||||||||||
LYS | C:159 | C:150 | 50.0 | NA | -72.7 | 164.2 | 50.0 | NA | NA | ||||||||||||||
7cft | 1 | P78348 | 91.05 | 0.0 |
EM |
2020-10-21 | LYS | A:159 | A:150 | 38.0 | NA | -136.1 | 163.7 | 38.0 | NA | NA | |||||||
LYS | B:159 | B:150 | 36.0 | NA | -136.0 | 163.8 | 36.0 | NA | NA | ||||||||||||||
LYS | C:159 | C:150 | 36.0 | NA | -136.0 | 163.7 | 36.0 | NA | NA | ||||||||||||||
6l6i | 1 | P78348 | 90.0 | 0.0 |
X-RAY |
2020-11-04 | LYS | A:140 | A:150 | 114.0 | 0.57 | -101.1 | 173.7 | 114.0 | 0.57 | 0.0 | |||||||
LYS | B:140 | B:150 | 132.0 | 0.66 | -98.3 | 172.9 | 132.0 | 0.66 | 0.0 | ||||||||||||||
LYS | C:140 | C:150 | 150.0 | 0.75 | -105.9 | 173.7 | 150.0 | 0.75 | 0.0 | ||||||||||||||
6l6n | 1 | P78348 | 90.0 | 0.0 |
X-RAY |
2021-01-13 | LYS | A:140 | A:150 | 109.0 | 0.545 | -102.2 | 162.4 | 109.0 | 0.545 | 0.0 |
HOH |
6.889 |
CB |
O |
|||
LYS | B:140 | B:150 | 133.0 | 0.665 | -100.0 | 158.3 | 133.0 | 0.665 | 0.0 |
HOH |
5.708 |
CG |
O |
||||||||||
LYS | C:140 | C:150 | 122.0 | 0.61 | -100.8 | 159.8 | 122.0 | 0.61 | 0.0 | ||||||||||||||
4nyk | 1 | Q1XA76 | 81.29 | 0.0 |
X-RAY |
2014-02-12 | LYS | A:155 | A:151 | 112.0 | 0.56 | -127.3 | 160.2 | 112.0 | 0.56 | 0.0 |
HOH |
4.111 |
CE |
O |
|||
3ij4 | 1 | Q1XA76 | 81.29 | 0.0 |
X-RAY |
2009-11-10 | LYS | A:150 | A:151 | 109.0 | 0.545 | -115.1 | 161.0 | 109.0 | 0.545 | 0.0 |
HOH |
4.364 |
CE |
O |
|||
4fz0 | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2012-08-01 | LYS | A:138 | A:151 | 127.0 | 0.635 | -92.5 | 174.5 | 127.0 | 0.635 | 0.0 | |||||||
LYS | B:138 | B:151 | 126.0 | 0.63 | -92.6 | 174.4 | 126.0 | 0.63 | 0.0 |
HOH |
9.581 |
CG |
O |
||||||||||
LYS | C:138 | C:151 | 128.0 | 0.64 | -94.1 | 173.7 | 128.0 | 0.64 | 0.0 |
GOL HOH |
9.554 5.578 |
O CB |
O1 O |
||||||||||
4fz1 | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2012-08-01 | LYS | A:138 | A:151 | 51.0 | NA | -146.3 | 149.4 | 51.0 | NA | NA | |||||||
4ntw | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2014-02-19 | LYS | A:138 | A:151 | 124.0 | 0.62 | -110.9 | 164.3 | 124.0 | 0.62 | 0.0 |
HOH |
2.362 |
NZ |
O |
|||
4ntx | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2014-02-19 | LYS | A:138 | A:151 | 119.0 | 0.595 | -105.4 | 164.4 | 119.0 | 0.595 | 0.0 |
HOH |
4.054 |
NZ |
O |
|||
4nty | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2014-02-19 | LYS | A:138 | A:151 | 119.0 | 0.595 | -89.7 | 165.8 | 119.0 | 0.595 | 0.0 |
HOH |
3.217 |
CG |
O |
|||
6cmc | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2018-08-08 | LYS | A:138 | A:151 | 112.0 | 0.56 | -127.5 | 159.9 | 112.0 | 0.56 | 0.0 | |||||||
5wku | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-03-14 | LYS | A:127 | A:151 | 50.0 | NA | -122.4 | 159.7 | 50.0 | NA | NA | |||||||
LYS | B:127 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | C:127 | B:151 | 46.0 | NA | -76.7 | 159.3 | 46.0 | NA | NA | ||||||||||||||
5wkv | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-03-14 | LYS | A:127 | A:151 | 50.0 | NA | -101.5 | 164.1 | 50.0 | NA | NA | |||||||
LYS | B:127 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | C:127 | B:151 | 45.0 | NA | -77.3 | 156.9 | 45.0 | NA | NA | ||||||||||||||
5wkx | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-08-08 | LYS | A:127 | A:151 | 50.0 | NA | -122.4 | 159.8 | 50.0 | NA | NA | |||||||
LYS | B:127 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | C:127 | B:151 | 46.0 | NA | -76.6 | 159.3 | 46.0 | NA | NA | ||||||||||||||
5wky | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-08-08 | LYS | A:127 | A:151 | 50.0 | NA | -122.3 | 159.7 | 50.0 | NA | NA | |||||||
LYS | B:127 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | C:127 | B:151 | 47.0 | NA | -76.8 | 159.3 | 47.0 | NA | NA | ||||||||||||||
2qts | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2007-09-25 | LYS | A:126 | A:151 | 113.0 | 0.565 | -114.7 | 161.9 | 113.0 | 0.565 | 0.0 |
HOH |
2.984 |
NZ |
O |
|||
LYS | B:126 | B:151 | 121.0 | 0.605 | -106.3 | 158.2 | 121.0 | 0.605 | 0.0 |
HOH |
2.806 |
NZ |
O |
||||||||||
LYS | C:126 | C:151 | 118.0 | 0.59 | -110.8 | 161.7 | 118.0 | 0.59 | 0.0 |
HOH |
3.610 |
CB |
O |
||||||||||
LYS | D:126 | D:151 | 139.0 | 0.695 | -104.2 | 162.5 | NA | NA | NA | ||||||||||||||
LYS | E:126 | E:151 | 123.0 | 0.615 | -111.8 | 166.6 | NA | NA | NA | ||||||||||||||
LYS | F:126 | F:151 | 119.0 | 0.595 | -120.1 | 163.1 | NA | NA | NA | ||||||||||||||
6x9h | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2020-12-30 | LYS | A:126 | A:151 | 108.0 | 0.54 | -108.2 | 162.8 | 108.0 | 0.54 | 0.0 | |||||||
LYS | B:126 | B:151 | 137.0 | 0.685 | -107.9 | 162.6 | 137.0 | 0.685 | 0.0 | ||||||||||||||
LYS | C:126 | C:151 | 126.0 | 0.63 | -109.1 | 164.9 | 126.0 | 0.63 | 0.0 | ||||||||||||||
3s3w | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2012-05-23 | LYS | A:147 | A:151 | 134.0 | 0.67 | -127.3 | 150.3 | 134.0 | 0.67 | 0.0 |
HOH |
5.272 |
NZ |
O |
|||
LYS | B:147 | B:151 | 131.0 | 0.655 | -127.2 | 150.2 | 131.0 | 0.655 | 0.0 |
HOH |
4.926 |
O |
O |
||||||||||
LYS | C:147 | C:151 | 133.0 | 0.665 | -127.1 | 150.3 | 133.0 | 0.665 | 0.0 |
HOH |
3.608 |
CB |
O |
||||||||||
3s3x | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2012-05-23 | LYS | A:147 | A:151 | 135.0 | 0.675 | -79.6 | 162.6 | 135.0 | 0.675 | 0.0 | |||||||
LYS | B:147 | B:151 | 135.0 | 0.675 | -79.7 | 162.5 | 135.0 | 0.675 | 0.0 | ||||||||||||||
LYS | C:147 | C:151 | 135.0 | 0.675 | -79.7 | 162.8 | 135.0 | 0.675 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p78348-f1 | 1 | P78348 | 91.99 | 0.0 | LYS | A:150 | A:150 | 144.0 | 0.72 | -96.1 | 158.3 |