Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50453627 . A C CCDS8796.1:NM_020039.3:c.448Aaa>Caa_NP_064423.2:p.150K>Q Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
2021-08-11 LYS B:150 D:150 46.0 NA -101.5 162.7 46.0 NA NA
6ave 1 Q1XA76 82.06 0.0 EM
2018-03-21 LYS A:151 A:151 26.0 NA -133.9 137.9 26.0 NA NA
LYS B:151 B:151 26.0 NA -133.9 137.9 26.0 NA NA
LYS C:151 C:151 27.0 NA -133.9 137.9 27.0 NA NA
6vtk 1 Q1XA76 82.06 0.0 EM
2020-03-11 LYS A:151 A:151 115.0 0.575 -104.5 158.2 115.0 0.575 0.0
LYS B:151 C:151 116.0 0.58 -104.5 158.2 116.0 0.58 0.0
LYS C:151 B:151 116.0 0.58 -104.5 158.2 116.0 0.58 0.0
6vtl 1 Q1XA76 82.06 0.0 EM
2020-03-11 LYS A:151 A:151 45.0 NA -113.1 155.7 45.0 NA NA
LYS B:151 C:151 45.0 NA -113.1 155.7 45.0 NA NA
LYS C:151 B:151 45.0 NA -113.1 155.7 45.0 NA NA
7cfs 1 P78348 91.05 0.0 EM
2020-10-21 LYS A:159 A:150 52.0 NA -72.7 164.2 52.0 NA NA
LYS B:159 B:150 50.0 NA -72.7 164.2 50.0 NA NA
LYS C:159 C:150 50.0 NA -72.7 164.2 50.0 NA NA
7cft 1 P78348 91.05 0.0 EM
2020-10-21 LYS A:159 A:150 38.0 NA -136.1 163.7 38.0 NA NA
LYS B:159 B:150 36.0 NA -136.0 163.8 36.0 NA NA
LYS C:159 C:150 36.0 NA -136.0 163.7 36.0 NA NA
6l6i 1 P78348 90.0 0.0 X-RAY
2020-11-04 LYS A:140 A:150 114.0 0.57 -101.1 173.7 114.0 0.57 0.0
LYS B:140 B:150 132.0 0.66 -98.3 172.9 132.0 0.66 0.0
LYS C:140 C:150 150.0 0.75 -105.9 173.7 150.0 0.75 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
2021-01-13 LYS A:140 A:150 109.0 0.545 -102.2 162.4 109.0 0.545 0.0 HOH
6.889
CB
O
LYS B:140 B:150 133.0 0.665 -100.0 158.3 133.0 0.665 0.0 HOH
5.708
CG
O
LYS C:140 C:150 122.0 0.61 -100.8 159.8 122.0 0.61 0.0
4nyk 1 Q1XA76 81.29 0.0 X-RAY
2014-02-12 LYS A:155 A:151 112.0 0.56 -127.3 160.2 112.0 0.56 0.0 HOH
4.111
CE
O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
2009-11-10 LYS A:150 A:151 109.0 0.545 -115.1 161.0 109.0 0.545 0.0 HOH
4.364
CE
O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
2012-08-01 LYS A:138 A:151 127.0 0.635 -92.5 174.5 127.0 0.635 0.0
LYS B:138 B:151 126.0 0.63 -92.6 174.4 126.0 0.63 0.0 HOH
9.581
CG
O
LYS C:138 C:151 128.0 0.64 -94.1 173.7 128.0 0.64 0.0 GOL
HOH
9.554
5.578
O
CB
O1
O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
2012-08-01 LYS A:138 A:151 51.0 NA -146.3 149.4 51.0 NA NA
4ntw 1 Q1XA76 81.89 0.0 X-RAY
2014-02-19 LYS A:138 A:151 124.0 0.62 -110.9 164.3 124.0 0.62 0.0 HOH
2.362
NZ
O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
2014-02-19 LYS A:138 A:151 119.0 0.595 -105.4 164.4 119.0 0.595 0.0 HOH
4.054
NZ
O
4nty 1 Q1XA76 81.89 0.0 X-RAY
2014-02-19 LYS A:138 A:151 119.0 0.595 -89.7 165.8 119.0 0.595 0.0 HOH
3.217
CG
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
2018-08-08 LYS A:138 A:151 112.0 0.56 -127.5 159.9 112.0 0.56 0.0
5wku 1 Q1XA76 81.52 0.0 X-RAY
2018-03-14 LYS A:127 A:151 50.0 NA -122.4 159.7 50.0 NA NA
LYS B:127 NA:NA DO NA DO DO DO NA NA NA
LYS C:127 B:151 46.0 NA -76.7 159.3 46.0 NA NA
5wkv 1 Q1XA76 81.52 0.0 X-RAY
2018-03-14 LYS A:127 A:151 50.0 NA -101.5 164.1 50.0 NA NA
LYS B:127 NA:NA DO NA DO DO DO NA NA NA
LYS C:127 B:151 45.0 NA -77.3 156.9 45.0 NA NA
5wkx 1 Q1XA76 81.52 0.0 X-RAY
2018-08-08 LYS A:127 A:151 50.0 NA -122.4 159.8 50.0 NA NA
LYS B:127 NA:NA DO NA DO DO DO NA NA NA
LYS C:127 B:151 46.0 NA -76.6 159.3 46.0 NA NA
5wky 1 Q1XA76 81.52 0.0 X-RAY
2018-08-08 LYS A:127 A:151 50.0 NA -122.3 159.7 50.0 NA NA
LYS B:127 NA:NA DO NA DO DO DO NA NA NA
LYS C:127 B:151 47.0 NA -76.8 159.3 47.0 NA NA
2qts 1 Q1XA76 81.48 0.0 X-RAY
2007-09-25 LYS A:126 A:151 113.0 0.565 -114.7 161.9 113.0 0.565 0.0 HOH
2.984
NZ
O
LYS B:126 B:151 121.0 0.605 -106.3 158.2 121.0 0.605 0.0 HOH
2.806
NZ
O
LYS C:126 C:151 118.0 0.59 -110.8 161.7 118.0 0.59 0.0 HOH
3.610
CB
O
LYS D:126 D:151 139.0 0.695 -104.2 162.5 NA NA NA
LYS E:126 E:151 123.0 0.615 -111.8 166.6 NA NA NA
LYS F:126 F:151 119.0 0.595 -120.1 163.1 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
2020-12-30 LYS A:126 A:151 108.0 0.54 -108.2 162.8 108.0 0.54 0.0
LYS B:126 B:151 137.0 0.685 -107.9 162.6 137.0 0.685 0.0
LYS C:126 C:151 126.0 0.63 -109.1 164.9 126.0 0.63 0.0
3s3w 1 Q1XA76 81.48 0.0 X-RAY
2012-05-23 LYS A:147 A:151 134.0 0.67 -127.3 150.3 134.0 0.67 0.0 HOH
5.272
NZ
O
LYS B:147 B:151 131.0 0.655 -127.2 150.2 131.0 0.655 0.0 HOH
4.926
O
O
LYS C:147 C:151 133.0 0.665 -127.1 150.3 133.0 0.665 0.0 HOH
3.608
CB
O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
2012-05-23 LYS A:147 A:151 135.0 0.675 -79.6 162.6 135.0 0.675 0.0
LYS B:147 B:151 135.0 0.675 -79.7 162.5 135.0 0.675 0.0
LYS C:147 C:151 135.0 0.675 -79.7 162.8 135.0 0.675 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 LYS A:150 A:150 144.0 0.72 -96.1 158.3