Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50471024 . C A CCDS8796.1:NM_020039.3:c.587aCg>aAg_NP_064423.2:p.196T>K Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 THR B:196 D:196 3.0 0.021 E -116.9 127.5 3.0 0.021 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 THR A:197 A:197 5.0 0.036 E -138.8 124.4 5.0 0.036 0.0
THR B:197 B:197 5.0 0.036 E -138.7 124.4 5.0 0.036 0.0
THR C:197 C:197 5.0 0.036 E -138.8 124.4 5.0 0.036 0.0
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 THR A:197 A:197 9.0 0.064 E -127.4 117.5 9.0 0.064 0.0
THR B:197 C:197 11.0 0.079 E -127.4 117.6 11.0 0.079 0.0
THR C:197 B:197 10.0 0.071 E -127.4 117.6 10.0 0.071 0.0
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 THR A:197 A:197 5.0 0.036 E -141.5 104.6 5.0 0.036 0.0
THR B:197 C:197 5.0 0.036 E -141.5 104.7 5.0 0.036 0.0
THR C:197 B:197 5.0 0.036 E -141.4 104.7 5.0 0.036 0.0
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 THR A:205 A:196 7.0 0.05 E -142.9 126.5 7.0 0.05 0.0
THR B:205 B:196 9.0 0.064 E -142.9 126.6 9.0 0.064 0.0
THR C:205 C:196 7.0 0.05 E -142.8 126.6 7.0 0.05 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 THR A:205 A:196 6.0 0.043 E -149.8 116.4 6.0 0.043 0.0
THR B:205 B:196 6.0 0.043 E -149.8 116.3 6.0 0.043 0.0
THR C:205 C:196 7.0 0.05 E -149.8 116.4 7.0 0.05 0.0
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 THR A:186 A:196 1.0 0.007 E -101.0 125.1 1.0 0.007 0.0
THR B:186 B:196 0.0 0.0 E -100.2 124.6 0.0 0.0 0.0
THR C:186 C:196 0.0 0.0 E -99.4 124.7 0.0 0.0 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 THR A:186 A:196 0.0 0.0 E -118.7 121.4 0.0 0.0 0.0
THR B:186 B:196 0.0 0.0 E -119.0 123.2 0.0 0.0 0.0 HOH
 6.692
 O
 O
THR C:186 C:196 0.0 0.0 E -119.4 121.7 0.0 0.0 0.0 HOH
 6.035
 OG1
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 THR A:201 A:197 9.0 0.064 E -123.7 116.3 9.0 0.064 0.0
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 THR A:196 A:197 9.0 0.064 E -119.2 114.1 9.0 0.064 0.0
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 THR A:184 A:197 10.0 0.071 E -124.6 122.5 10.0 0.071 0.0 HOH
 3.897
 CG2
 O
THR B:184 B:197 9.0 0.064 E -127.9 121.1 9.0 0.064 0.0 HOH
 2.514
 OG1
 O
THR C:184 C:197 8.0 0.057 E -128.2 120.1 8.0 0.057 0.0 HOH
 2.585
 OG1
 O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 THR A:184 A:197 16.0 0.114 E -108.9 109.6 16.0 0.114 0.0
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:184 A:197 8.0 0.057 E -114.3 119.6 8.0 0.057 0.0 HOH
 2.704
 OG1
 O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:184 A:197 8.0 0.057 E -116.4 120.0 8.0 0.057 0.0 HOH
 2.842
 OG1
 O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:184 A:197 9.0 0.064 E -110.6 123.2 9.0 0.064 0.0 CS
HOH
 7.202
2.802
 O
OG1
 CS
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 THR A:184 A:197 8.0 0.057 E -123.9 115.6 8.0 0.057 0.0
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 THR A:173 A:197 4.0 0.029 E -124.3 116.2 4.0 0.029 0.0
THR B:173 C:197 5.0 0.036 E -123.0 116.8 5.0 0.036 0.0
THR C:173 B:197 3.0 0.021 E -121.8 116.6 3.0 0.021 0.0
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 THR A:173 A:197 4.0 0.029 E -124.0 116.1 4.0 0.029 0.0
THR B:173 C:197 4.0 0.029 E -123.0 116.6 4.0 0.029 0.0
THR C:173 B:197 3.0 0.021 E -121.7 116.5 3.0 0.021 0.0
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 THR A:173 A:197 4.0 0.029 E -124.3 116.2 4.0 0.029 0.0
THR B:173 C:197 5.0 0.036 E -123.0 116.8 5.0 0.036 0.0
THR C:173 B:197 3.0 0.021 E -121.8 116.6 3.0 0.021 0.0
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 THR A:173 A:197 4.0 0.029 E -124.3 116.2 4.0 0.029 0.0
THR B:173 C:197 5.0 0.036 E -123.0 116.8 5.0 0.036 0.0
THR C:173 B:197 3.0 0.021 E -121.7 116.5 3.0 0.021 0.0
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 THR A:172 A:197 9.0 0.064 E -121.7 123.6 9.0 0.064 0.0 HOH
 2.791
 OG1
 O
THR B:172 B:197 8.0 0.057 E -119.5 122.1 8.0 0.057 0.0 HOH
 2.679
 OG1
 O
THR C:172 C:197 8.0 0.057 E -119.3 123.0 8.0 0.057 0.0 HOH
 2.755
 OG1
 O
THR D:172 D:197 10.0 0.071 E -122.5 124.8 NA NA NA
THR E:172 E:197 8.0 0.057 E -121.3 124.8 NA NA NA
THR F:172 F:197 9.0 0.064 E -120.6 124.9 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 THR A:172 A:197 10.0 0.071 E -122.5 114.5 10.0 0.071 0.0
THR B:172 B:197 10.0 0.071 E -119.7 112.4 10.0 0.071 0.0
THR C:172 C:197 10.0 0.071 E -118.9 114.7 10.0 0.071 0.0
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 THR A:193 A:197 9.0 0.064 E -119.2 124.1 9.0 0.064 0.0 HOH
 2.528
 OG1
 O
THR B:193 B:197 7.0 0.05 E -119.8 123.7 7.0 0.05 0.0 HOH
 2.743
 OG1
 O
THR C:193 C:197 10.0 0.071 E -119.5 123.6 10.0 0.071 0.0 HOH
 3.137
 O
 O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 THR A:193 A:197 8.0 0.057 E -133.2 112.4 8.0 0.057 0.0
THR B:193 B:197 10.0 0.071 E -133.2 112.4 10.0 0.071 0.0
THR C:193 C:197 10.0 0.071 E -133.4 112.6 10.0 0.071 0.0 HOH
 5.768
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 THR A:196 A:196 9.0 0.064 E -108.9 113.4