Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128206 . G A CCDS8539.1:NM_000552.3:c.4378Ctt>Ttt_NP_000543.2:p.1460L>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 LEU A:235 A:1460 41.0 0.241 H -75.0 -24.0 41.0 0.241 0.0 HOH
 2.995
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 LEU A:202 A:697 48.0 0.282 T -82.5 -17.2 48.0 0.282 0.0 HOH
 5.327
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 LEU C:201 C:697 37.0 0.218 T -103.9 -12.9 37.0 0.218 0.0 HOH
 8.636
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:201 A:697 42.0 0.247 T -95.0 -12.1 42.0 0.247 0.0 HOH
 3.410
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:201 A:697 39.0 0.229 T -94.7 5.7 39.0 0.229 0.0 HOH
 3.127
 CD1
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 LEU A:224 A:224 47.0 0.276 T -77.4 -12.5 47.0 0.276 0.0 HOH
 2.918
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 LEU A:200 A:697 50.0 0.294 H -77.7 -34.2 50.0 0.294 0.0 HOH
 2.748
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 LEU A:200 A:697 28.0 0.165 T -96.1 -1.5 28.0 0.165 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 LEU A:200 A:697 36.0 0.212 T -102.3 -35.7 36.0 0.212 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 LEU A:199 AAA:1460 46.0 0.271 T -76.5 -11.0 46.0 0.271 0.0 HOH
 2.400
 HB2
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:198 A:697 40.0 0.235 H -72.5 -29.3 40.0 0.235 0.0 HOH
 3.006
 CD1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:198 A:697 31.0 0.182 T -106.4 -5.4 31.0 0.182 0.0 HOH
 9.172
 CD2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 LEU A:202 A:697 22.0 0.129 T -99.6 -34.6 22.0 0.129 0.0 HOH
 5.583
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 LEU A:198 A:1460 46.0 0.271 H -84.2 -45.0 46.0 0.271 0.0 HOH
 3.717
 CD2
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 LEU C:191 A:697 22.0 0.129 T -91.7 0.4 22.0 0.129 0.0 HOH
 2.912
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 LEU C:191 A:697 38.0 0.224 T -84.9 -10.3 38.0 0.224 0.0 HOH
 2.822
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:198 A:1460 45.0 0.265 H -79.5 -15.7 45.0 0.265 0.0 HOH
 3.794
 CD2
 O
LEU B:198 B:1460 45.0 0.265 H -79.1 -18.7 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:198 A:1460 28.0 0.165 T -88.0 -5.1 28.0 0.165 0.0
LEU C:198 C:1460 44.0 0.259 G -95.7 6.4 NA NA NA
LEU E:198 E:1460 39.0 0.229 T -94.7 5.7 NA NA NA
LEU G:198 G:1460 37.0 0.218 T -95.8 -2.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 LEU C:200 C:697 43.0 0.253 T -110.9 5.9 43.0 0.253 0.0 HOH
 3.186
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 LEU A:1260 A:1260 40.0 0.235 T -78.8 -13.0
af-p04275-f3 1 P04275 99.93 0.0 LEU A:1060 A:1060 37.0 0.218 T -79.0 -7.0
af-p04275-f6 1 P04275 100.0 0.0 LEU A:460 A:460 35.0 0.206 T -84.3 -12.0
af-p04275-f5 1 P04275 99.93 0.0 LEU A:660 A:660 39.0 0.229 T -81.2 -9.6
af-p04275-f8 1 P04275 100.0 0.0 LEU A:60 A:60 57.0 0.335 T -95.9 -5.5
af-p04275-f7 1 P04275 100.0 0.0 LEU A:260 A:260 37.0 0.218 T -86.5 -0.7
af-p04275-f4 1 P04275 99.93 0.0 LEU A:860 A:860 39.0 0.229 T -81.4 -6.2