Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128340 . C A CCDS8539.1:NM_000552.3:c.4244gGc>gTc_NP_000543.2:p.1415G>V Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLY A:190 A:1415 1.0 0.013 E -87.1 125.3 1.0 0.013 0.0 HOH
 3.433
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLY A:157 A:652 1.0 0.013 E -73.0 122.0 1.0 0.013 0.0 HOH
 3.236
 C
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLY C:156 C:652 0.0 0.0 E -88.3 132.4 0.0 0.0 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLY A:156 A:652 1.0 0.013 E -65.4 123.5 1.0 0.013 0.0 DC
HOH
 8.700
5.800
 CA
O
 N4
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLY A:156 A:652 0.0 0.0 E -85.8 96.1 0.0 0.0 0.0 DC
HOH
 8.820
6.882
 CA
C
 N4
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLY A:179 A:179 0.0 0.0 E -81.1 132.7 0.0 0.0 0.0 HOH
 3.192
 C
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLY A:155 A:652 0.0 0.0 E -89.0 126.1 0.0 0.0 0.0 HOH
 6.131
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLY A:155 A:652 1.0 0.013 E -82.0 130.4 1.0 0.013 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLY A:155 A:652 0.0 0.0 E -52.3 150.1 0.0 0.0 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLY A:154 AAA:1415 1.0 0.013 E -79.7 122.6 1.0 0.013 0.0 HOH
 3.256
 HA3
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLY A:153 A:652 1.0 0.013 E -84.7 123.1 1.0 0.013 0.0 HOH
 3.306
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLY A:153 A:652 0.0 0.0 E -83.6 129.7 0.0 0.0 0.0 HOH
 3.659
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLY A:157 A:652 0.0 0.0 E -70.3 126.1 0.0 0.0 0.0 HOH
 3.656
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLY A:153 A:1415 0.0 0.0 E -79.0 125.3 0.0 0.0 0.0 HOH
 6.604
 C
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLY C:146 A:652 1.0 0.013 E -77.9 136.6 1.0 0.013 0.0 HOH
 6.510
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLY C:146 A:652 0.0 0.0 E -78.2 132.7 0.0 0.0 0.0 HOH
 3.380
 C
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLY A:153 A:1415 2.0 0.027 E -78.7 115.5 2.0 0.027 0.0 HOH
 3.165
 O
 O
GLY B:153 B:1415 2.0 0.027 E -79.1 115.0 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLY A:153 A:1415 0.0 0.0 E -84.0 132.5 0.0 0.0 0.0
GLY C:153 C:1415 0.0 0.0 E -81.0 135.8 NA NA NA
GLY E:153 E:1415 0.0 0.0 E -81.6 120.6 NA NA NA
GLY G:153 G:1415 0.0 0.0 E -88.3 137.3 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLY C:155 C:652 0.0 0.0 E -79.0 108.5 0.0 0.0 0.0 HOH
 8.156
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 GLY A:1215 A:1215 0.0 0.0 E -81.5 123.4
af-p04275-f3 1 P04275 99.93 0.0 GLY A:1015 A:1015 0.0 0.0 E -83.1 125.8
af-p04275-f6 1 P04275 100.0 0.0 GLY A:415 A:415 0.0 0.0 E -78.8 124.1
af-p04275-f5 1 P04275 99.93 0.0 GLY A:615 A:615 0.0 0.0 E -82.3 124.9
af-p04275-f8 1 P04275 100.0 0.0 GLY A:15 A:15 6.0 0.08 E -103.6 112.7
af-p04275-f7 1 P04275 100.0 0.0 GLY A:215 A:215 0.0 0.0 E -81.3 125.4
af-p04275-f4 1 P04275 99.93 0.0 GLY A:815 A:815 0.0 0.0 E -81.7 125.2