Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128359 . C A CCDS8539.1:NM_000552.3:c.4225Gtc>Ttc_NP_000543.2:p.1409V>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 VAL A:184 A:1409 2.0 0.013 E -90.8 111.9 2.0 0.013 0.0 HOH
 2.774
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 VAL A:151 A:646 3.0 0.019 E -88.7 114.8 3.0 0.019 0.0 A2M
OMG
HOH
 8.344
9.061
2.738
 CG2
CG2
O
 N1
O6
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 VAL C:150 C:646 3.0 0.019 E -93.5 99.8 3.0 0.019 0.0 HOH
 4.763
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:150 A:646 4.0 0.026 E -112.7 115.8 4.0 0.026 0.0 HOH
 2.846
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:150 A:646 5.0 0.032 E -120.1 108.2 5.0 0.032 0.0 HOH
 4.598
 CA
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 VAL A:173 A:173 4.0 0.026 E -98.3 118.2 4.0 0.026 0.0 HOH
 2.629
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 VAL A:149 A:646 1.0 0.006 E -94.6 115.7 1.0 0.006 0.0 HOH
 2.939
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 VAL A:149 A:646 5.0 0.032 E -95.1 112.3 5.0 0.032 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 VAL A:149 A:646 4.0 0.026 E -98.1 128.6 4.0 0.026 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 VAL A:148 AAA:1409 3.0 0.019 E -96.7 120.5 3.0 0.019 0.0 HOH
 2.530
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:147 A:646 2.0 0.013 E -93.6 109.3 2.0 0.013 0.0 HOH
 2.720
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:147 A:646 3.0 0.019 E -102.8 119.9 3.0 0.019 0.0 HOH
 3.076
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 VAL A:151 A:646 6.0 0.039 E -114.6 117.4 6.0 0.039 0.0 HOH
 3.930
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 VAL A:147 A:1409 4.0 0.026 E -100.5 124.7 4.0 0.026 0.0 HOH
 2.660
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 VAL C:140 A:646 2.0 0.013 E -107.5 111.7 2.0 0.013 0.0 HOH
 2.689
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 VAL C:140 A:646 3.0 0.019 E -106.0 115.0 3.0 0.019 0.0 HOH
 2.710
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:147 A:1409 3.0 0.019 E -98.1 115.4 3.0 0.019 0.0 HOH
 2.959
 O
 O
VAL B:147 B:1409 3.0 0.019 E -97.8 116.8 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:147 A:1409 4.0 0.026 -126.7 116.2 4.0 0.026 0.0
VAL C:147 C:1409 3.0 0.019 E -118.0 114.0 NA NA NA
VAL E:147 E:1409 3.0 0.019 -125.1 121.0 NA NA NA
VAL G:147 G:1409 4.0 0.026 E -114.0 115.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 VAL C:149 C:646 4.0 0.026 E -114.2 116.0 4.0 0.026 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 VAL A:1209 A:1209 5.0 0.032 E -93.4 122.8
af-p04275-f3 1 P04275 99.93 0.0 VAL A:1009 A:1009 6.0 0.039 E -93.9 129.0
af-p04275-f6 1 P04275 100.0 0.0 VAL A:409 A:409 6.0 0.039 E -92.8 123.6
af-p04275-f5 1 P04275 99.93 0.0 VAL A:609 A:609 7.0 0.045 E -94.4 126.4
af-p04275-f8 1 P04275 100.0 0.0 VAL A:9 A:9 67.0 0.432 -82.9 118.0
af-p04275-f7 1 P04275 100.0 0.0 VAL A:209 A:209 6.0 0.039 E -102.8 124.7
af-p04275-f4 1 P04275 99.93 0.0 VAL A:809 A:809 5.0 0.032 E -93.8 125.6