Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128422 . G A CCDS8539.1:NM_000552.3:c.4162Cag>Tag_NP_000543.2:p.1388Q>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLN A:163 A:1388 118.0 0.656 -122.5 127.4 118.0 0.656 0.0 HOH
 2.735
 OE1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLN A:130 A:625 126.0 0.7 -123.5 117.4 126.0 0.7 0.0 OMG
OMG
OMG
HOH
 9.195
7.233
8.510
2.973
 OE1
OE1
OE1
NE2
 O3'
OP1
OP1
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLN C:129 C:625 120.0 0.667 -128.8 118.2 120.0 0.667 0.0 HOH
 6.607
 NE2
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:129 A:625 120.0 0.667 -123.8 121.8 120.0 0.667 0.0 DG
DT
DG
DC
DC
DT
HOH
 8.849
5.640
2.860
3.424
3.846
8.801
3.255
 O
O
O
NE2
NE2
NE2
N
 N7
C7
O6
C6
N3
O2
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:129 A:625 110.0 0.611 -121.6 111.6 110.0 0.611 0.0 DG
DT
DG
DC
DC
DT
HOH
 8.661
5.695
2.903
3.023
4.518
8.168
3.624
 O
O
O
NE2
NE2
NE2
CA
 N7
C7
N1
C5
N3
O2
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLN A:152 A:152 127.0 0.706 -124.2 120.1 127.0 0.706 0.0 HOH
 2.845
 OE1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLN A:128 A:625 114.0 0.633 -136.9 128.3 114.0 0.633 0.0 HOH
 3.254
 N
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLN A:128 A:625 121.0 0.672 -151.3 103.3 121.0 0.672 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLN A:128 A:625 108.0 0.6 -129.3 124.9 108.0 0.6 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLN A:127 AAA:1388 138.0 0.767 -136.3 119.9 138.0 0.767 0.0 HOH
 2.237
 H
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:126 A:625 110.0 0.611 -127.0 124.3 110.0 0.611 0.0 HOH
 2.627
 NE2
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:126 A:625 109.0 0.606 -127.0 117.9 109.0 0.606 0.0 HOH
 3.437
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLN A:130 A:625 129.0 0.717 -134.4 113.3 129.0 0.717 0.0 HOH
 2.865
 OE1
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLN A:126 A:1388 108.0 0.6 -144.6 107.3 108.0 0.6 0.0 HOH
 2.736
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLN C:119 A:625 124.0 0.689 -146.0 107.9 122.0 0.678 0.011 B:1890294:0.011
 HOH
 3.167
 OE1
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLN C:119 A:625 122.0 0.678 -134.1 115.5 122.0 0.678 0.0 HOH
 2.758
 NE2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:126 A:1388 119.0 0.661 -138.8 109.7 119.0 0.661 0.0 ACT
PEG
HOH
 7.694
2.882
3.053
 O
NE2
N
 CH3
O1
O
GLN B:126 B:1388 120.0 0.667 -138.3 110.4 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:126 A:1388 106.0 0.589 -144.2 112.0 106.0 0.589 0.0 SO4
HOH
 7.879
3.327
 OE1
CB
 O4
O
GLN C:126 C:1388 126.0 0.7 -144.3 110.3 NA NA NA
GLN E:126 E:1388 126.0 0.7 -133.4 104.4 NA NA NA
GLN G:126 G:1388 122.0 0.678 -144.6 110.6 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLN C:128 C:625 107.0 0.594 -140.3 135.1 105.0 0.583 0.011 B:P22030:0.011

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 GLN A:1388 A:1388 179.0 0.994 -111.4 132.9
af-p04275-f2 1 P04275 99.93 0.0 GLN A:1188 A:1188 119.0 0.661 -100.6 128.6
af-p04275-f3 1 P04275 99.93 0.0 GLN A:988 A:988 122.0 0.678 -102.7 125.8
af-p04275-f6 1 P04275 100.0 0.0 GLN A:388 A:388 116.0 0.644 -101.0 120.6
af-p04275-f5 1 P04275 99.93 0.0 GLN A:588 A:588 117.0 0.65 -107.9 123.9
af-p04275-f7 1 P04275 100.0 0.0 GLN A:188 A:188 120.0 0.667 -125.0 118.3
af-p04275-f4 1 P04275 99.93 0.0 GLN A:788 A:788 115.0 0.639 -106.8 122.9