Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128565 . A C CCDS8539.1:NM_000552.3:c.4019cTg>cGg_NP_000543.2:p.1340L>R Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 LEU A:115 A:1340 5.0 0.029 H -59.7 -42.4 5.0 0.029 0.0 HOH
 3.576
 CD1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 LEU A:82 A:577 7.0 0.041 H -64.2 -41.8 7.0 0.041 0.0 HOH
 4.483
 CD1
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 LEU C:81 C:577 5.0 0.029 H -70.9 -49.3 5.0 0.029 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:81 A:577 5.0 0.029 H -58.4 -39.9 5.0 0.029 0.0 HOH
 3.303
 CD2
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:81 A:577 9.0 0.053 H -56.0 -38.8 9.0 0.053 0.0 HOH
 5.238
 CD1
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 LEU A:104 A:104 4.0 0.024 H -61.9 -41.3 4.0 0.024 0.0 HOH
 3.655
 CD1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 LEU A:80 A:577 4.0 0.024 H -59.5 -45.4 4.0 0.024 0.0 HOH
 4.541
 CD1
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 LEU A:80 A:577 5.0 0.029 H -51.7 -39.4 5.0 0.029 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 LEU A:80 A:577 9.0 0.053 H -53.1 -77.4 9.0 0.053 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 LEU A:79 AAA:1340 7.0 0.041 H -52.8 -46.9 7.0 0.041 0.0 HOH
 3.601
 HD12
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:78 A:577 4.0 0.024 H -64.3 -41.2 4.0 0.024 0.0 HOH
 3.550
 CB
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:78 A:577 5.0 0.029 H -55.8 -41.2 5.0 0.029 0.0 HOH
 4.213
 CD2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 LEU A:82 A:577 13.0 0.076 H -66.2 -43.7 13.0 0.076 0.0 HOH
 4.037
 CD1
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 LEU A:78 A:1340 0.0 0.0 H -59.1 -46.5 0.0 0.0 0.0 HOH
 5.113
 CD2
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 LEU C:71 A:577 6.0 0.035 H -62.8 -40.1 6.0 0.035 0.0 HOH
 3.670
 CD1
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 LEU C:71 A:577 9.0 0.053 H -71.1 -39.3 9.0 0.053 0.0 HOH
 4.055
 CB
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:78 A:1340 4.0 0.024 H -61.3 -40.5 4.0 0.024 0.0 HOH
 4.207
 CD1
 O
LEU B:78 B:1340 4.0 0.024 H -62.6 -41.8 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:78 A:1340 9.0 0.053 H -72.2 -18.7 9.0 0.053 0.0 MES
 7.662
 N
 O2S
LEU C:78 C:1340 9.0 0.053 H -65.4 -24.9 NA NA NA
LEU E:78 E:1340 8.0 0.047 H -68.0 -27.5 NA NA NA
LEU G:78 G:1340 11.0 0.065 H -63.3 -30.3 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 LEU C:80 C:577 16.0 0.094 H -75.7 -39.9 16.0 0.094 0.0 HOH
 3.185
 CD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 LEU A:1340 A:1340 8.0 0.047 H -61.6 -44.4
af-p04275-f2 1 P04275 99.93 0.0 LEU A:1140 A:1140 8.0 0.047 H -60.5 -46.6
af-p04275-f3 1 P04275 99.93 0.0 LEU A:940 A:940 8.0 0.047 H -61.2 -46.2
af-p04275-f6 1 P04275 100.0 0.0 LEU A:340 A:340 8.0 0.047 H -62.0 -44.7
af-p04275-f5 1 P04275 99.93 0.0 LEU A:540 A:540 8.0 0.047 H -59.4 -45.6
af-p04275-f7 1 P04275 100.0 0.0 LEU A:140 A:140 8.0 0.047 H -62.8 -44.6
af-p04275-f4 1 P04275 99.93 0.0 LEU A:740 A:740 8.0 0.047 H -58.9 -46.3