Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128578 . G A CCDS8539.1:NM_000552.3:c.4006Cga>Tga_NP_000543.2:p.1336R>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ARG A:111 A:1336 127.0 0.564 -54.2 141.9 127.0 0.564 0.0 HOH
 2.804
 NE
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ARG A:78 A:573 196.0 0.871 -70.0 147.4 196.0 0.871 0.0 HOH
 3.560
 CB
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ARG C:77 C:573 172.0 0.764 -69.3 136.0 172.0 0.764 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:77 A:573 194.0 0.862 -61.7 136.5 194.0 0.862 0.0 HOH
 2.843
 NH1
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:77 A:573 145.0 0.644 -105.6 134.6 145.0 0.644 0.0 HOH
 6.646
 NH2
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ARG A:100 A:100 151.0 0.671 -64.9 146.1 151.0 0.671 0.0 HOH
 2.937
 N
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ARG A:76 A:573 94.0 0.418 -70.6 152.1 94.0 0.418 0.0 HOH
 3.175
 N
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ARG A:76 A:573 100.0 0.444 -65.9 134.4 100.0 0.444 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ARG A:76 A:573 167.0 0.742 -56.6 145.4 167.0 0.742 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ARG A:75 AAA:1336 169.0 0.751 -65.1 126.0 169.0 0.751 0.0 HOH
 4.047
 HH22
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:74 A:573 127.0 0.564 -58.4 143.1 127.0 0.564 0.0 HOH
 2.790
 NH1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:74 A:573 192.0 0.853 -61.4 145.2 192.0 0.853 0.0 HOH
 4.142
 CD
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ARG A:78 A:573 189.0 0.84 -76.0 154.5 182.0 0.809 0.031 B:P07359:0.031
 HOH
 4.131
 CB
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ARG A:74 A:1336 161.0 0.716 -68.1 144.8 161.0 0.716 0.0 HOH
 2.774
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ARG C:67 A:573 195.0 0.867 -60.8 141.3 195.0 0.867 0.0 HOH
 2.866
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ARG C:67 A:573 188.0 0.836 -62.8 143.5 188.0 0.836 0.0 HOH
 2.925
 N
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:74 A:1336 160.0 0.711 -62.4 144.4 160.0 0.711 0.0 HOH
 4.925
 N
 O
ARG B:74 B:1336 149.0 0.662 -62.0 144.3 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:74 A:1336 171.0 0.76 -65.4 148.3 171.0 0.76 0.0 MES
 3.002
 NH1
 O2S
ARG C:74 C:1336 190.0 0.844 -66.9 146.7 NA NA NA
ARG E:74 E:1336 185.0 0.822 -63.7 145.2 NA NA NA
ARG G:74 G:1336 179.0 0.796 -73.3 149.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ARG C:76 C:573 167.0 0.742 -68.9 146.4 167.0 0.742 0.0 HOH
 7.515
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ARG A:1336 A:1336 147.0 0.653 -62.1 144.3
af-p04275-f2 1 P04275 99.93 0.0 ARG A:1136 A:1136 193.0 0.858 -63.0 145.5
af-p04275-f3 1 P04275 99.93 0.0 ARG A:936 A:936 104.0 0.462 -61.7 144.8
af-p04275-f6 1 P04275 100.0 0.0 ARG A:336 A:336 159.0 0.707 -63.1 145.8
af-p04275-f5 1 P04275 99.93 0.0 ARG A:536 A:536 189.0 0.84 -62.0 146.0
af-p04275-f7 1 P04275 100.0 0.0 ARG A:136 A:136 134.0 0.596 -64.5 148.0
af-p04275-f4 1 P04275 99.93 0.0 ARG A:736 A:736 147.0 0.653 -64.3 145.5