Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128638 . C A CCDS8539.1:NM_000552.3:c.3946Gtg>Ttg_NP_000543.2:p.1316V>L Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 VAL A:91 A:1316 4.0 0.026 E -127.6 148.9 4.0 0.026 0.0 HOH
 2.956
 N
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 VAL A:58 A:553 3.0 0.019 E -124.5 144.9 3.0 0.019 0.0 HOH
 2.827
 N
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 VAL C:57 C:553 4.0 0.026 E -128.8 146.2 4.0 0.026 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:57 A:553 4.0 0.026 E -119.7 148.5 4.0 0.026 0.0 HOH
 3.031
 N
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:57 A:553 4.0 0.026 E -134.1 142.7 4.0 0.026 0.0 HOH
 2.853
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 VAL A:80 A:80 3.0 0.019 E -125.5 150.2 3.0 0.019 0.0 HOH
 2.992
 N
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 VAL A:56 A:553 4.0 0.026 E -128.4 150.0 4.0 0.026 0.0 HOH
 5.753
 N
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 VAL A:56 A:553 5.0 0.032 -91.5 168.7 5.0 0.032 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 VAL A:56 A:553 6.0 0.039 E -149.8 170.2 6.0 0.039 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 VAL A:55 AAA:1316 3.0 0.019 E -119.2 145.1 3.0 0.019 0.0 HOH
 1.877
 H
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:54 A:553 4.0 0.026 E -129.9 154.1 4.0 0.026 0.0 HOH
 2.923
 N
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:54 A:553 4.0 0.026 E -127.5 155.4 4.0 0.026 0.0 HOH
 2.843
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 VAL A:58 A:553 8.0 0.052 E -118.1 160.6 8.0 0.052 0.0 HOH
 3.433
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 VAL A:54 A:1316 0.0 0.0 E -129.8 154.5 0.0 0.0 0.0 HOH
 5.926
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 VAL C:47 A:553 4.0 0.026 E -133.8 149.6 4.0 0.026 0.0 HOH
 3.280
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 VAL C:47 A:553 4.0 0.026 E -131.4 156.4 4.0 0.026 0.0 HOH
 2.862
 N
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:54 A:1316 4.0 0.026 E -121.6 154.0 4.0 0.026 0.0 HOH
 3.037
 N
 O
VAL B:54 B:1316 3.0 0.019 E -122.2 153.3 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:54 A:1316 4.0 0.026 E -116.2 158.6 4.0 0.026 0.0
VAL C:54 C:1316 4.0 0.026 E -106.6 157.8 NA NA NA
VAL E:54 E:1316 4.0 0.026 E -108.9 154.5 NA NA NA
VAL G:54 G:1316 6.0 0.039 E -114.0 156.5 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 VAL C:56 C:553 4.0 0.026 E -124.4 146.0 4.0 0.026 0.0 HOH
 2.932
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 VAL A:1316 A:1316 5.0 0.032 E -123.8 134.1
af-p04275-f2 1 P04275 99.93 0.0 VAL A:1116 A:1116 4.0 0.026 E -121.3 145.1
af-p04275-f3 1 P04275 99.93 0.0 VAL A:916 A:916 5.0 0.032 E -122.1 147.0
af-p04275-f6 1 P04275 100.0 0.0 VAL A:316 A:316 4.0 0.026 E -113.3 144.3
af-p04275-f5 1 P04275 99.93 0.0 VAL A:516 A:516 6.0 0.039 E -119.0 143.8
af-p04275-f7 1 P04275 100.0 0.0 VAL A:116 A:116 6.0 0.039 E -115.8 148.9
af-p04275-f4 1 P04275 99.93 0.0 VAL A:716 A:716 5.0 0.032 E -122.2 145.1