Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 6128640 | . | C | A | CCDS8539.1:NM_000552.3:c.3944cGc>cTc_NP_000543.2:p.1315R>L | Homo sapiens von Willebrand factor (VWF), mRNA. |
---|---|---|---|---|---|---|---|
|
|
|
|
PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5bv8 | 1 | P04275 | 99.11 | 3e-149 |
X-RAY |
2015-12-23 | ARG | A:90 | A:1315 | 15.0 | 0.067 | E | -102.0 | 147.5 | 15.0 | 0.067 | 0.0 |
HOH |
2.922 |
NH1 |
O |
||
7f49 | 1 | P04275 | 99.05 | 2e-140 |
X-RAY |
2021-07-07 | ARG | A:57 | A:552 | 22.0 | 0.098 | E | -96.8 | 142.6 | 22.0 | 0.098 | 0.0 |
HOH |
3.565 |
CA |
O |
||
1uex | 3 | P04275 | 99.52 | 3e-140 |
X-RAY |
2003-09-30 | ARG | C:56 | C:552 | 13.0 | 0.058 | E | -89.1 | 149.3 | 13.0 | 0.058 | 0.0 |
HOH |
3.796 |
NH1 |
O |
||
3hxo | 1 | P04275 | 99.52 | 3e-140 |
X-RAY |
2009-11-17 | ARG | A:56 | A:552 | 10.0 | 0.044 | E | -100.9 | 139.5 | 10.0 | 0.044 | 0.0 |
HOH |
3.448 |
CA |
O |
||
3hxq | 1 | P04275 | 99.52 | 3e-140 |
X-RAY |
2009-11-17 | ARG | A:56 | A:552 | 9.0 | 0.04 | E | -96.1 | 146.5 | 9.0 | 0.04 | 0.0 |
HOH |
3.267 |
CA |
O |
||
7eow | 1 | P04275 | 100.0 | 7e-140 |
X-RAY |
2021-07-07 | ARG | A:79 | A:79 | 7.0 | 0.031 | E | -105.8 | 143.7 | 7.0 | 0.031 | 0.0 |
HOH |
3.225 |
NH2 |
O |
||
1auq | 1 | P04275 | 99.52 | 1e-139 |
X-RAY |
1998-10-14 | ARG | A:55 | A:552 | 6.0 | 0.027 | E | -106.6 | 145.4 | 6.0 | 0.027 | 0.0 |
HOH |
4.430 |
NH1 |
O |
||
1u0n | 1 | P04275 | 99.52 | 1e-139 |
X-RAY |
2005-04-19 | ARG | A:55 | A:552 | 15.0 | 0.067 | E | -112.7 | 119.4 | 15.0 | 0.067 | 0.0 | ||||||
1m10 | 1 | P04275 | 99.04 | 7e-139 |
X-RAY |
2002-08-28 | ARG | A:55 | A:552 | 16.0 | 0.071 | E | -99.4 | 160.2 | 16.0 | 0.071 | 0.0 | ||||||
7a6o | 1 | L8E853 | 99.51 | 5e-137 |
X-RAY |
2021-03-03 | ARG | A:54 | AAA:1315 | 12.0 | 0.053 | E | -95.3 | 137.7 | 12.0 | 0.053 | 0.0 |
HOH |
2.600 |
HA |
O |
||
1ijb | 1 | P04275 | 99.01 | 4e-134 |
X-RAY |
2002-07-10 | ARG | A:53 | A:552 | 4.0 | 0.018 | E | -99.5 | 149.7 | 4.0 | 0.018 | 0.0 |
HOH |
3.418 |
CA |
O |
||
1ijk | 1 | P04275 | 99.01 | 4e-134 |
X-RAY |
2002-07-10 | ARG | A:53 | A:552 | 7.0 | 0.031 | E | -108.9 | 145.6 | 7.0 | 0.031 | 0.0 |
HOH |
3.666 |
CA |
O |
||
1sq0 | 1 | P04275 | 99.01 | 5e-134 |
X-RAY |
2004-04-13 | ARG | A:57 | A:552 | 32.0 | 0.142 | E | -113.7 | 135.6 | 32.0 | 0.142 | 0.0 |
HOH |
3.646 |
NH2 |
O |
||
4c2a | 1 | P04275 | 98.48 | 3e-130 |
X-RAY |
2014-01-08 | ARG | A:53 | A:1315 | 27.0 | 0.12 | E | -113.7 | 146.4 | 27.0 | 0.12 | 0.0 |
HOH |
2.930 |
NH1 |
O |
||
1oak | 3 | P04275 | 99.49 | 1e-128 |
X-RAY |
1998-10-21 | ARG | C:46 | A:552 | 19.0 | 0.084 | E | -94.8 | 149.0 | 19.0 | 0.084 | 0.0 |
HOH |
4.256 |
NH2 |
O |
||
1fns | 3 | P04275 | 98.97 | 2e-128 |
X-RAY |
2000-10-18 | ARG | C:46 | A:552 | 14.0 | 0.062 | E | -97.7 | 152.7 | 14.0 | 0.062 | 0.0 |
HOH |
2.568 |
NH2 |
O |
||
4c29 | 1 | P04275 | 98.48 | 4e-128 |
X-RAY |
2014-01-08 | ARG | A:53 | A:1315 | 7.0 | 0.031 | E | -104.8 | 144.1 | 7.0 | 0.031 | 0.0 |
HOH |
3.760 |
CA |
O |
||
ARG | B:53 | B:1315 | 5.0 | 0.022 | E | -105.4 | 143.2 | NA | NA | NA | |||||||||||||
4c2b | 1 | P04275 | 98.48 | 4e-128 |
X-RAY |
2014-01-08 | ARG | A:53 | A:1315 | 19.0 | 0.084 | E | -101.2 | 142.6 | 19.0 | 0.084 | 0.0 |
HOH |
7.164 |
NH1 |
O |
||
ARG | C:53 | C:1315 | 8.0 | 0.036 | E | -97.6 | 139.9 | NA | NA | NA | |||||||||||||
ARG | E:53 | E:1315 | 6.0 | 0.027 | E | -104.3 | 139.3 | NA | NA | NA | |||||||||||||
ARG | G:53 | G:1315 | 22.0 | 0.098 | E | -104.0 | 138.9 | NA | NA | NA | |||||||||||||
1u0o | 3 | Q8CIZ8 | 87.02 | 2e-119 |
X-RAY |
2005-04-19 | ARG | C:55 | C:552 | 8.0 | 0.036 | E | -113.0 | 133.3 | 8.0 | 0.036 | 0.0 |
HOH |
3.728 |
CA |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p04275-f1 | 1 | P04275 | 99.93 | 0.0 | ARG | A:1315 | A:1315 | 25.0 | 0.111 | E | -88.0 | 138.9 | |
af-p04275-f2 | 1 | P04275 | 99.93 | 0.0 | ARG | A:1115 | A:1115 | 11.0 | 0.049 | E | -93.0 | 137.4 | |
af-p04275-f3 | 1 | P04275 | 99.93 | 0.0 | ARG | A:915 | A:915 | 15.0 | 0.067 | E | -95.7 | 137.3 | |
af-p04275-f6 | 1 | P04275 | 100.0 | 0.0 | ARG | A:315 | A:315 | 12.0 | 0.053 | E | -90.4 | 130.1 | |
af-p04275-f5 | 1 | P04275 | 99.93 | 0.0 | ARG | A:515 | A:515 | 12.0 | 0.053 | E | -90.4 | 134.4 | |
af-p04275-f7 | 1 | P04275 | 100.0 | 0.0 | ARG | A:115 | A:115 | 10.0 | 0.044 | E | -91.6 | 132.7 | |
af-p04275-f4 | 1 | P04275 | 99.93 | 0.0 | ARG | A:715 | A:715 | 20.0 | 0.089 | E | -94.3 | 137.8 |