Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128644 . C A CCDS8539.1:NM_000552.3:c.3940Gtc>Ttc_NP_000543.2:p.1314V>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 VAL A:89 A:1314 0.0 0.0 E -96.7 123.7 0.0 0.0 0.0 HOH
 4.566
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 VAL A:56 A:551 0.0 0.0 E -88.9 119.0 0.0 0.0 0.0 HOH
 5.032
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 VAL C:55 C:551 0.0 0.0 E -118.5 108.3 0.0 0.0 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:55 A:551 0.0 0.0 E -95.0 116.5 0.0 0.0 0.0 HOH
 4.824
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:55 A:551 0.0 0.0 E -104.0 103.6 0.0 0.0 0.0 HOH
 4.801
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 VAL A:78 A:78 0.0 0.0 E -94.9 124.8 0.0 0.0 0.0 HOH
 4.607
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 VAL A:54 A:551 0.0 0.0 E -103.3 123.9 0.0 0.0 0.0 HOH
 5.100
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 VAL A:54 A:551 0.0 0.0 E -95.2 124.7 0.0 0.0 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 VAL A:54 A:551 1.0 0.006 E -132.2 112.4 1.0 0.006 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 VAL A:53 AAA:1314 0.0 0.0 E -95.1 121.3 0.0 0.0 0.0 HOH
 4.588
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:52 A:551 0.0 0.0 E -99.9 119.8 0.0 0.0 0.0 HOH
 4.839
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:52 A:551 0.0 0.0 E -92.6 127.0 0.0 0.0 0.0 HOH
 5.155
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 VAL A:56 A:551 8.0 0.052 E -101.4 133.9 8.0 0.052 0.0 HOH
 3.169
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 VAL A:52 A:1314 4.0 0.026 E -114.5 114.6 4.0 0.026 0.0 ACT
HOH
 8.683
3.665
 CG1
CG1
 CH3
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 VAL C:45 A:551 0.0 0.0 E -96.0 113.9 0.0 0.0 0.0 HOH
 5.169
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 VAL C:45 A:551 0.0 0.0 E -99.7 116.7 0.0 0.0 0.0 HOH
 4.788
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:52 A:1314 1.0 0.006 E -107.9 123.2 1.0 0.006 0.0 HOH
 3.331
 CG2
 O
VAL B:52 B:1314 1.0 0.006 E -108.8 122.5 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:52 A:1314 1.0 0.006 E -115.2 120.1 1.0 0.006 0.0
VAL C:52 C:1314 2.0 0.013 E -118.4 114.8 NA NA NA
VAL E:52 E:1314 2.0 0.013 E -113.1 125.4 NA NA NA
VAL G:52 G:1314 4.0 0.026 E -108.6 121.2 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ILE C:54 C:551 0.0 0.0 E -104.8 124.6 0.0 0.0 0.0 HOH
 4.127
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 VAL A:1314 A:1314 0.0 0.0 E -103.8 115.3
af-p04275-f2 1 P04275 99.93 0.0 VAL A:1114 A:1114 0.0 0.0 E -105.0 117.7
af-p04275-f3 1 P04275 99.93 0.0 VAL A:914 A:914 0.0 0.0 E -108.6 118.5
af-p04275-f6 1 P04275 100.0 0.0 VAL A:314 A:314 0.0 0.0 E -107.0 114.2
af-p04275-f5 1 P04275 99.93 0.0 VAL A:514 A:514 0.0 0.0 E -108.6 113.7
af-p04275-f7 1 P04275 100.0 0.0 VAL A:114 A:114 0.0 0.0 E -96.2 115.3
af-p04275-f4 1 P04275 99.93 0.0 VAL A:714 A:714 0.0 0.0 E -103.3 116.5