Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128737 . C A CCDS8539.1:NM_000552.3:c.3847Gat>Tat_NP_000543.2:p.1283D>Y Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ASP A:58 A:1283 1.0 0.007 E -57.0 119.6 1.0 0.007 0.0 HOH
 2.711
 OD2
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ASP A:25 A:520 0.0 0.0 E -57.5 118.8 0.0 0.0 0.0 HOH
 2.675
 OD2
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ASP C:24 C:520 1.0 0.007 E -51.9 124.8 1.0 0.007 0.0 HOH
 3.002
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASP A:24 A:520 1.0 0.007 E -64.6 120.0 1.0 0.007 0.0 DG
HOH
 9.463
2.598
 OD1
OD1
 O6
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASP A:24 A:520 1.0 0.007 E -49.2 120.5 1.0 0.007 0.0 HOH
 3.201
 OD2
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ASP A:47 A:47 1.0 0.007 E -58.1 119.7 1.0 0.007 0.0 HOH
 2.522
 OD2
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ASP A:23 A:520 0.0 0.0 E -60.5 121.9 0.0 0.0 0.0 HOH
 2.982
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ASP A:23 A:520 1.0 0.007 E -56.0 125.3 1.0 0.007 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ASP A:23 A:520 1.0 0.007 E -65.0 119.9 1.0 0.007 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ASP A:22 AAA:1283 1.0 0.007 E -61.0 121.5 1.0 0.007 0.0 HOH
 2.907
 OD2
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASP A:21 A:520 1.0 0.007 E -63.2 118.8 1.0 0.007 0.0 HOH
 2.757
 OD2
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASP A:21 A:520 0.0 0.0 E -58.5 127.0 0.0 0.0 0.0 HOH
 2.886
 OD2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ASP A:25 A:520 1.0 0.007 E -63.2 120.9 1.0 0.007 0.0 HOH
 2.666
 OD2
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ASP A:21 A:1283 0.0 0.0 E -58.5 120.4 0.0 0.0 0.0 HOH
 3.083
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ASP C:14 A:520 0.0 0.0 E -58.1 120.6 0.0 0.0 0.0 HOH
 3.077
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ASP C:14 A:520 1.0 0.007 E -63.0 117.7 1.0 0.007 0.0 HOH
 2.683
 OD2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASP A:21 A:1283 1.0 0.007 E -62.4 121.3 1.0 0.007 0.0 HOH
 2.469
 OD2
 O
ASP B:21 B:1283 1.0 0.007 E -62.1 120.4 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASP A:21 A:1283 1.0 0.007 E -67.7 125.0 1.0 0.007 0.0 HOH
 9.606
 OD1
 O
ASP C:21 C:1283 1.0 0.007 E -70.1 126.3 NA NA NA
ASP E:21 E:1283 0.0 0.0 E -64.7 134.2 NA NA NA
ASP G:21 G:1283 1.0 0.007 E -68.4 126.6 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ASP C:23 C:520 0.0 0.0 E -64.8 81.2 0.0 0.0 0.0 HOH
 9.515
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ASP A:1283 A:1283 0.0 0.0 E -64.8 111.3
af-p04275-f2 1 P04275 99.93 0.0 ASP A:1083 A:1083 0.0 0.0 E -69.6 107.5
af-p04275-f3 1 P04275 99.93 0.0 ASP A:883 A:883 1.0 0.007 E -71.3 110.5
af-p04275-f6 1 P04275 100.0 0.0 ASP A:283 A:283 1.0 0.007 E -69.4 106.5
af-p04275-f5 1 P04275 99.93 0.0 ASP A:483 A:483 1.0 0.007 E -71.7 110.3
af-p04275-f7 1 P04275 100.0 0.0 ASP A:83 A:83 1.0 0.007 E -71.1 106.5
af-p04275-f4 1 P04275 99.93 0.0 ASP A:683 A:683 1.0 0.007 E -69.5 110.1