Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6924044 . G A CCDS8562.1:NM_000616.4:c.493Ggg>Agg_NP_000607.1:p.165G>R Homo sapiens CD4 molecule (CD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7t0o 4 P01730 100.0 0.0 EM
 2022-01-12 GLY G:140 H:140 24.0 0.32 E -164.1 178.2 24.0 0.32 0.0
GLY I:140 L:140 27.0 0.36 E -165.9 178.4 27.0 0.36 0.0
GLY K:140 M:140 27.0 0.36 E -165.8 178.4 27.0 0.36 0.0
7t0r 3 P01730 99.73 0.0 X-RAY
 2022-01-12 GLY C:140 A:140 27.0 0.36 E -164.6 -178.2 18.0 0.24 0.12 B:None:0.12
GLY F:140 D:140 28.0 0.373 E -168.2 -179.8 NA NA NA
1wio 1 P01730 100.0 0.0 X-RAY
 1997-07-07 GLY A:140 A:140 26.0 0.347 E -160.8 -149.7 26.0 0.347 0.0
GLY B:140 B:140 25.0 0.333 E -161.5 -155.1 NA NA NA
1wip 1 P01730 100.0 0.0 X-RAY
 1997-07-07 GLY A:140 A:140 29.0 0.387 E -160.8 -149.7 29.0 0.387 0.0
GLY B:140 B:140 26.0 0.347 E -161.5 -155.2 NA NA NA
1wiq 1 P01730 100.0 0.0 X-RAY
 1997-07-07 GLY A:140 A:140 30.0 0.4 E -160.8 -149.7 30.0 0.4 0.0
GLY B:140 B:140 24.0 0.32 E -161.5 -155.2 NA NA NA
5u1f 5 P01730 100.0 0.0 EM
 2017-02-22 GLY I:140 M:1140 33.0 0.44 E 178.8 -155.5 33.0 0.44 0.0
6met 2 P01730 100.0 0.0 EM
 2018-12-12 GLY B:140 A:140 43.0 0.573 -166.3 -142.2 43.0 0.573 0.0
3t0e 5 P01730 99.45 0.0 X-RAY
 2012-03-07 GLY E:140 E:140 29.0 0.387 -95.0 -142.8 29.0 0.387 0.0
4q6i 3 P01730 100.0 1e-148 X-RAY
 2014-07-23 GLY C:165 C:140 31.0 0.413 E -175.5 -163.6 NA NA NA
GLY I:165 I:140 30.0 0.4 E -175.2 -163.9 NA NA NA
GLY J:165 J:140 31.0 0.413 E -175.2 -163.1 NA NA NA
GLY K:165 K:140 31.0 0.413 E -175.4 -163.2 31.0 0.413 0.0
1g9m 2 P01730 99.46 6e-129 X-RAY
 2000-12-27 GLY B:140 C:140 19.0 0.253 E -158.1 158.3 19.0 0.253 0.0 HOH
 5.312
 N
 O
1g9n 2 P01730 99.46 6e-129 X-RAY
 2000-12-27 GLY B:140 C:140 9.0 0.12 E -147.7 123.4 9.0 0.12 0.0 HOH
 8.899
 N
 O
1gc1 2 P01730 99.46 6e-129 X-RAY
 1998-07-08 GLY B:140 C:140 24.0 0.32 E -170.1 -174.2 24.0 0.32 0.0 HOH
 4.000
 N
 O
1rzj 2 P01730 99.46 6e-129 X-RAY
 2004-02-03 GLY B:140 C:140 28.0 0.373 E -176.6 -178.7 28.0 0.373 0.0 HOH
 4.449
 C
 O
1rzk 2 P01730 99.46 6e-129 X-RAY
 2004-02-03 GLY B:140 C:140 11.0 0.147 E -164.4 111.4 11.0 0.147 0.0 HOH
 9.074
 N
 O
3j70 3 P01730 99.46 6e-129 EM
 2015-08-26 GLY C:140 C:140 27.0 0.36 E -173.5 174.3 27.0 0.36 0.0
GLY H:140 O:140 28.0 0.373 E -173.6 174.3 28.0 0.373 0.0
GLY M:140 T:140 26.0 0.347 E -173.5 174.3 26.0 0.347 0.0
4h8w 4 P01730 99.46 6e-129 X-RAY
 2014-04-09 GLY D:140 C:140 13.0 0.173 -116.1 172.3 13.0 0.173 0.0 HOH
 4.206
 CA
 O
4jm2 6 P01730 99.46 6e-129 X-RAY
 2013-05-29 GLY F:140 F:140 26.0 0.347 E -177.4 -166.5 26.0 0.347 0.0
4rqs 1 P01730 99.46 6e-129 X-RAY
 2014-12-31 GLY A:140 B:140 21.0 0.28 E -160.7 156.4 21.0 0.28 0.0
5a8h 2 P01730 99.46 6e-129 EM
 2015-08-05 GLY B:140 B:140 11.0 0.147 E -164.4 111.4 11.0 0.147 0.0
GLY H:140 H:140 10.0 0.133 E -164.4 111.5 10.0 0.133 0.0
GLY N:140 N:140 9.0 0.12 E -164.4 111.4 9.0 0.12 0.0
5vn3 4 P01730 99.46 6e-129 EM
 2017-07-12 GLY D:140 C:140 23.0 0.307 -176.7 -171.7 23.0 0.307 0.0
GLY I:140 E:140 23.0 0.307 -176.7 -171.7 23.0 0.307 0.0
GLY N:140 F:140 24.0 0.32 -176.7 -171.7 24.0 0.32 0.0
6edu 3 P01730 99.46 6e-129 EM
 2018-10-17 GLY G:140 NA:NA DO NA DO DO DO NA NA NA
GLY H:140 NA:NA DO NA DO DO DO NA NA NA
GLY I:140 NA:NA DO NA DO DO DO NA NA NA
2nxy 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 32.0 0.427 E -177.9 -165.1 32.0 0.427 0.0 HOH
 4.342
 O
 O
2nxz 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 29.0 0.387 E 175.5 -169.5 29.0 0.387 0.0 HOH
 5.401
 N
 O
2ny0 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 30.0 0.4 E 171.0 -164.8 30.0 0.4 0.0 HOH
 6.280
 N
 O
2ny1 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 29.0 0.387 E -176.3 -164.8 29.0 0.387 0.0 HOH
 3.024
 C
 O
2ny2 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 33.0 0.44 E -179.3 -152.2 33.0 0.44 0.0 HOH
 5.777
 CA
 O
2ny3 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 27.0 0.36 E -172.3 -164.2 27.0 0.36 0.0 HOH
 3.881
 O
 O
2ny4 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 33.0 0.44 E 178.8 -155.2 33.0 0.44 0.0 HOH
 7.083
 O
 O
2ny5 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 C:1140 35.0 0.467 E 162.4 -161.7 35.0 0.467 0.0 HOH
 5.549
 N
 O
2ny6 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 GLY B:141 B:1140 30.0 0.4 E 166.2 -150.5 30.0 0.4 0.0 HOH
 5.080
 CA
 O
3jwd 2 P01730 100.0 7e-129 X-RAY
 2009-12-29 GLY B:141 C:1140 19.0 0.253 E -179.4 156.2 19.0 0.253 0.0 HOH
 5.074
 CA
 O
GLY F:141 D:1140 13.0 0.173 E -159.3 144.9 NA NA NA
3jwo 2 P01730 100.0 7e-129 X-RAY
 2009-12-29 GLY B:141 C:1140 19.0 0.253 E -179.4 156.3 19.0 0.253 0.0
4r2g 2 P01730 100.0 7e-129 X-RAY
 2014-10-08 GLY B:141 F:140 6.0 0.08 E -140.3 124.2 6.0 0.08 0.0
GLY E:141 B:140 21.0 0.28 E -178.8 167.3 NA NA NA
GLY H:141 H:140 27.0 0.36 E 165.0 169.5 NA NA NA
GLY K:141 L:140 9.0 0.12 E -139.8 150.8 NA NA NA
5cay 2 P01730 100.0 7e-129 X-RAY
 2015-12-09 GLY B:141 B:140 33.0 0.44 -147.5 -143.8 33.0 0.44 0.0
3o2d 3 P01730 100.0 3e-128 X-RAY
 2010-12-22 GLY C:140 A:140 25.0 0.333 E -161.6 -172.5 16.0 0.213 0.12 B:None:0.12
 HOH
 4.105
 CA
 O
3cd4 1 P01730 100.0 3e-128 X-RAY
 1993-10-31 GLY A:140 A:140 30.0 0.4 E -155.9 -143.5 30.0 0.4 0.0
3lqa 1 P01730 100.0 4e-128 X-RAY
 2010-04-07 GLY A:140 C:140 25.0 0.333 -60.0 -39.9 25.0 0.333 0.0
5thr 3 P01730 100.0 4e-128 EM
 2016-11-16 GLY G:140 NA:NA DO NA DO DO DO NA NA NA
GLY H:140 NA:NA DO NA DO DO DO NA NA NA
GLY I:140 NA:NA DO NA DO DO DO NA NA NA
6cm3 3 P01730 100.0 4e-128 EM
 2018-10-17 GLY G:140 NA:NA DO NA DO DO DO NA NA NA
GLY H:140 NA:NA DO NA DO DO DO NA NA NA
GLY I:140 NA:NA DO NA DO DO DO NA NA NA
6u0l 2 P01730 100.0 4e-128 EM
 2019-12-11 GLY D:140 NA:NA DO NA DO DO DO NA NA NA
GLY E:140 NA:NA DO NA DO DO DO NA NA NA
GLY F:140 NA:NA DO NA DO DO DO NA NA NA
6u0n 2 P01730 100.0 4e-128 EM
 2019-12-11 GLY D:140 NA:NA DO NA DO DO DO NA NA NA
GLY E:140 NA:NA DO NA DO DO DO NA NA NA
GLY F:140 NA:NA DO NA DO DO DO NA NA NA
2b4c 2 P01730 100.0 2e-127 X-RAY
 2005-11-15 GLY B:140 C:140 50.0 0.667 -175.2 -147.2 50.0 0.667 0.0
2qad 2 P01730 100.0 2e-127 X-RAY
 2007-09-25 GLY B:140 B:140 37.0 0.493 -150.9 -150.9 37.0 0.493 0.0
GLY F:140 F:140 36.0 0.48 -150.8 -150.9 NA NA NA
5a7x 2 P01730 100.0 2e-127 EM
 2015-08-05 GLY B:140 B:140 10.0 0.133 E -164.4 111.4 10.0 0.133 0.0
GLY F:140 F:140 11.0 0.147 E -164.4 111.4 11.0 0.147 0.0
GLY J:140 J:140 10.0 0.133 E -164.4 111.4 10.0 0.133 0.0
4p9h 1 P01730 99.45 3e-127 X-RAY
 2014-05-21 GLY A:140 C:140 33.0 0.44 E 171.5 -172.2 33.0 0.44 0.0
6opn 3 P01730 98.37 8e-126 EM
 2020-10-21 GLY C:160 NA:NA DO NA DO DO DO NA NA NA
GLY F:160 NA:NA DO NA DO DO DO NA NA NA
GLY I:160 NA:NA DO NA DO DO DO NA NA NA
6opo 4 P01730 98.37 8e-126 EM
 2020-10-21 GLY D:160 NA:NA DO NA DO DO DO NA NA NA
GLY I:160 NA:NA DO NA DO DO DO NA NA NA
GLY N:160 NA:NA DO NA DO DO DO NA NA NA
6opp 4 P01730 98.37 8e-126 EM
 2020-10-21 GLY D:160 NA:NA DO NA DO DO DO NA NA NA
GLY M:160 NA:NA DO NA DO DO DO NA NA NA
GLY O:160 NA:NA DO NA DO DO DO NA NA NA
6opq 4 P01730 98.37 8e-126 EM
 2020-10-21 GLY D:160 NA:NA DO NA DO DO DO NA NA NA
GLY I:160 NA:NA DO NA DO DO DO NA NA NA
GLY N:160 NA:NA DO NA DO DO DO NA NA NA
6x5b 4 P01730 98.37 8e-126 EM
 2020-10-21 GLY D:160 NA:NA DO NA DO DO DO NA NA NA
GLY I:160 NA:NA DO NA DO DO DO NA NA NA
GLY N:160 NA:NA DO NA DO DO DO NA NA NA
6x5c 3 P01730 98.37 8e-126 EM
 2020-10-21 GLY C:160 NA:NA DO NA DO DO DO NA NA NA
GLY F:160 NA:NA DO NA DO DO DO NA NA NA
GLY I:160 NA:NA DO NA DO DO DO NA NA NA
1cdi 1 P01730 100.0 6e-125 X-RAY
 1994-04-30 GLY A:141 A:140 19.0 0.253 E -166.4 165.3 19.0 0.253 0.0
1cdh 1 P01730 100.0 7e-125 X-RAY
 1994-04-30 GLY A:140 A:140 33.0 0.44 E -169.7 -161.5 33.0 0.44 0.0 HOH
 6.665
 N
 O
1cdj 1 P01730 100.0 7e-125 X-RAY
 1997-04-01 GLY A:140 A:140 62.0 0.827 105.8 -97.3 62.0 0.827 0.0 HOH
 7.793
 O
 O
1jl4 4 P01730 100.0 7e-125 X-RAY
 2001-09-19 GLY D:140 D:140 30.0 0.4 E -155.8 -143.5 30.0 0.4 0.0
4r4h 2 P01730 100.0 7e-125 X-RAY
 2014-09-17 GLY B:140 B:140 32.0 0.427 E -178.6 -160.4 32.0 0.427 0.0
6l1y 2 P01730 100.0 4e-124 X-RAY
 2020-05-20 GLY B:140 C:140 23.0 0.307 E -173.9 163.8 23.0 0.307 0.0 HOH
 9.894
 N
 O
1cdy 1 P01730 99.44 6e-124 X-RAY
 1997-04-01 GLY A:140 A:140 28.0 0.373 B -174.8 -168.9 28.0 0.373 0.0 HOH
 9.271
 C
 O
1cdu 1 P01730 99.44 8e-124 X-RAY
 1997-04-01 GLY A:140 A:140 32.0 0.427 E 167.0 -168.9 32.0 0.427 0.0 HOH
 6.581
 N
 O
6meo 2 P01730 100.0 2e-123 EM
 2018-12-12 GLY B:140 A:140 43.0 0.573 -166.3 -142.2 43.0 0.573 0.0
3jcb 4 P01730 100.0 7e-123 EM
 2017-05-10 GLY D:140 D:140 52.0 0.693 -175.2 -147.3 52.0 0.693 0.0
3jcc 4 P01730 100.0 7e-123 EM
 2017-05-10 GLY D:140 D:140 43.0 0.573 E 169.6 -170.8 43.0 0.573 0.0
3s4s 4 P01730 98.88 9e-123 X-RAY
 2011-09-21 GLY D:144 G:140 32.0 0.427 176.7 -162.6 32.0 0.427 0.0
GLY H:144 H:140 27.0 0.36 -132.2 -150.4 NA NA NA
3s5l 4 P01730 97.74 3e-119 X-RAY
 2011-09-21 GLY G:144 G:140 22.0 0.293 B -165.8 -171.4 22.0 0.293 0.0 HOH
 7.350
 O
 O
GLY H:144 H:140 29.0 0.387 E 154.1 -162.9 NA NA NA
6tyb 2 F6XGD3 87.64 3e-101 X-RAY
 2019-10-02 GLY B:140 C:140 27.0 0.36 E 177.2 -170.6 27.0 0.36 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01730-f1 1 P01730 100.0 0.0 GLY A:165 A:165 25.0 0.333 E -168.2 -176.2