Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 6924122 | . | A | C | CCDS8562.1:NM_000616.4:c.571Aag>Cag_NP_000607.1:p.191K>Q | Homo sapiens CD4 molecule (CD4), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7t0o | 4 | P01730 | 100.0 | 0.0 |
EM |
2022-01-12 | LYS | G:166 | H:166 | 107.0 | 0.535 | E | -92.0 | 145.0 | 107.0 | 0.535 | 0.0 | ||||||
LYS | I:166 | L:166 | 112.0 | 0.56 | -93.8 | 145.1 | 112.0 | 0.56 | 0.0 | ||||||||||||||
LYS | K:166 | M:166 | 112.0 | 0.56 | -93.6 | 145.1 | 112.0 | 0.56 | 0.0 | ||||||||||||||
7t0r | 3 | P01730 | 99.73 | 0.0 |
X-RAY |
2022-01-12 | LYS | C:166 | A:166 | 112.0 | 0.56 | E | -111.8 | 138.2 | 98.0 | 0.49 | 0.07 |
B:None:0.07 |
|||||
LYS | F:166 | D:166 | 40.0 | NA | E | -114.0 | 137.0 | NA | NA | NA | |||||||||||||
1wio | 1 | P01730 | 100.0 | 0.0 |
X-RAY |
1997-07-07 | LYS | A:166 | A:166 | 82.0 | 0.41 | E | -111.3 | 163.0 | 82.0 | 0.41 | 0.0 | ||||||
LYS | B:166 | B:166 | 85.0 | 0.425 | E | -112.5 | 164.5 | NA | NA | NA | |||||||||||||
1wip | 1 | P01730 | 100.0 | 0.0 |
X-RAY |
1997-07-07 | LYS | A:166 | A:166 | 80.0 | 0.4 | E | -111.4 | 163.0 | 80.0 | 0.4 | 0.0 | ||||||
LYS | B:166 | B:166 | 85.0 | 0.425 | E | -112.5 | 164.5 | NA | NA | NA | |||||||||||||
1wiq | 1 | P01730 | 100.0 | 0.0 |
X-RAY |
1997-07-07 | LYS | A:166 | A:166 | 84.0 | 0.42 | E | -111.3 | 163.0 | 84.0 | 0.42 | 0.0 | ||||||
LYS | B:166 | B:166 | 85.0 | 0.425 | E | -112.6 | 164.5 | NA | NA | NA | |||||||||||||
5u1f | 5 | P01730 | 100.0 | 0.0 |
EM |
2017-02-22 | LYS | I:166 | M:1166 | 33.0 | NA | E | -91.3 | 156.2 | 33.0 | NA | NA | ||||||
6met | 2 | P01730 | 100.0 | 0.0 |
EM |
2018-12-12 | LYS | B:166 | A:166 | 96.0 | 0.48 | B | -130.9 | 143.2 | 96.0 | 0.48 | 0.0 | ||||||
3t0e | 5 | P01730 | 99.45 | 0.0 |
X-RAY |
2012-03-07 | LYS | E:166 | E:166 | 70.0 | 0.35 | E | -137.5 | 123.3 | 70.0 | 0.35 | 0.0 | ||||||
4q6i | 3 | P01730 | 100.0 | 1e-148 |
X-RAY |
2014-07-23 | LYS | C:191 | C:166 | 106.0 | 0.53 | E | -90.5 | 164.2 | NA | NA | NA | ||||||
LYS | I:191 | I:166 | 108.0 | 0.54 | E | -90.3 | 164.7 | NA | NA | NA | |||||||||||||
LYS | J:191 | J:166 | 109.0 | 0.545 | E | -91.1 | 164.9 | NA | NA | NA | |||||||||||||
LYS | K:191 | K:166 | 104.0 | 0.52 | E | -90.3 | 164.1 | 104.0 | 0.52 | 0.0 | |||||||||||||
1g9m | 2 | P01730 | 99.46 | 6e-129 |
X-RAY |
2000-12-27 | LYS | B:166 | C:166 | 88.0 | 0.44 | E | -104.6 | 167.9 | 88.0 | 0.44 | 0.0 |
HOH |
2.827 |
CA |
O |
||
1g9n | 2 | P01730 | 99.46 | 6e-129 |
X-RAY |
2000-12-27 | LYS | B:166 | C:166 | 78.0 | 0.39 | B | -117.7 | 169.8 | 78.0 | 0.39 | 0.0 |
HOH |
2.949 |
NZ |
O |
||
1gc1 | 2 | P01730 | 99.46 | 6e-129 |
X-RAY |
1998-07-08 | LYS | B:166 | C:166 | 74.0 | 0.37 | E | -110.4 | 157.8 | 74.0 | 0.37 | 0.0 |
HOH |
3.075 |
NZ |
O |
||
1rzj | 2 | P01730 | 99.46 | 6e-129 |
X-RAY |
2004-02-03 | LYS | B:166 | C:166 | 91.0 | 0.455 | E | -103.5 | 175.4 | 91.0 | 0.455 | 0.0 |
HOH |
3.986 |
CA |
O |
||
1rzk | 2 | P01730 | 99.46 | 6e-129 |
X-RAY |
2004-02-03 | LYS | B:166 | C:166 | 75.0 | 0.375 | E | -113.8 | 167.7 | 75.0 | 0.375 | 0.0 |
HOH |
2.791 |
NZ |
O |
||
3j70 | 3 | P01730 | 99.46 | 6e-129 |
EM |
2015-08-26 | LYS | C:166 | C:166 | 78.0 | 0.39 | E | -128.6 | 144.0 | 78.0 | 0.39 | 0.0 | ||||||
LYS | H:166 | O:166 | 78.0 | 0.39 | E | -128.6 | 144.0 | 78.0 | 0.39 | 0.0 | |||||||||||||
LYS | M:166 | T:166 | 79.0 | 0.395 | E | -128.5 | 144.0 | 79.0 | 0.395 | 0.0 | |||||||||||||
4h8w | 4 | P01730 | 99.46 | 6e-129 |
X-RAY |
2014-04-09 | LYS | D:166 | C:166 | 94.0 | 0.47 | E | -132.6 | 154.8 | 94.0 | 0.47 | 0.0 |
HOH |
3.229 |
CE |
O |
||
4jm2 | 6 | P01730 | 99.46 | 6e-129 |
X-RAY |
2013-05-29 | LYS | F:166 | F:166 | 98.0 | 0.49 | E | -120.2 | 155.4 | 98.0 | 0.49 | 0.0 | ||||||
4rqs | 1 | P01730 | 99.46 | 6e-129 |
X-RAY |
2014-12-31 | LYS | A:166 | B:166 | 83.0 | 0.415 | E | -81.9 | 153.8 | 83.0 | 0.415 | 0.0 | ||||||
5a8h | 2 | P01730 | 99.46 | 6e-129 |
EM |
2015-08-05 | LYS | B:166 | B:166 | 77.0 | 0.385 | E | -113.7 | 167.8 | 77.0 | 0.385 | 0.0 | ||||||
LYS | H:166 | H:166 | 76.0 | 0.38 | E | -113.7 | 167.7 | 76.0 | 0.38 | 0.0 | |||||||||||||
LYS | N:166 | N:166 | 76.0 | 0.38 | E | -113.8 | 167.8 | 76.0 | 0.38 | 0.0 | |||||||||||||
5vn3 | 4 | P01730 | 99.46 | 6e-129 |
EM |
2017-07-12 | LYS | D:166 | C:166 | 104.0 | 0.52 | E | -133.4 | 125.3 | 104.0 | 0.52 | 0.0 | ||||||
LYS | I:166 | E:166 | 105.0 | 0.525 | E | -133.4 | 125.4 | 105.0 | 0.525 | 0.0 | |||||||||||||
LYS | N:166 | F:166 | 105.0 | 0.525 | E | -133.4 | 125.5 | 105.0 | 0.525 | 0.0 | |||||||||||||
6edu | 3 | P01730 | 99.46 | 6e-129 |
EM |
2018-10-17 | LYS | G:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | H:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | I:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
2nxy | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 94.0 | 0.47 | E | -95.9 | 156.9 | 94.0 | 0.47 | 0.0 |
HOH |
3.517 |
CD |
O |
||
2nxz | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 89.0 | 0.445 | E | -78.0 | 158.3 | 89.0 | 0.445 | 0.0 |
HOH |
3.148 |
CA |
O |
||
2ny0 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 85.0 | 0.425 | E | -71.1 | 151.0 | 85.0 | 0.425 | 0.0 |
HOH |
3.570 |
CA |
O |
||
2ny1 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 85.0 | 0.425 | E | -90.5 | 161.3 | 85.0 | 0.425 | 0.0 |
HOH |
3.059 |
CA |
O |
||
2ny2 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 103.0 | 0.515 | E | -107.2 | 156.8 | 103.0 | 0.515 | 0.0 |
HOH |
4.192 |
CD |
O |
||
2ny3 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 91.0 | 0.455 | E | -88.1 | 159.9 | 91.0 | 0.455 | 0.0 |
HOH |
3.407 |
CA |
O |
||
2ny4 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 101.0 | 0.505 | E | -98.0 | 153.5 | 101.0 | 0.505 | 0.0 |
HOH |
3.800 |
CG |
O |
||
2ny5 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | C:1166 | 112.0 | 0.56 | E | -103.2 | 155.4 | 112.0 | 0.56 | 0.0 |
HOH |
7.518 |
N |
O |
||
2ny6 | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2007-02-06 | LYS | B:167 | B:1166 | 101.0 | 0.505 | E | -134.4 | 140.9 | 101.0 | 0.505 | 0.0 | ||||||
3jwd | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2009-12-29 | LYS | B:167 | C:1166 | 143.0 | 0.715 | E | -117.3 | 175.6 | 143.0 | 0.715 | 0.0 |
HOH |
5.240 |
CD |
O |
||
LYS | F:167 | D:1166 | 120.0 | 0.6 | E | -125.3 | 177.1 | NA | NA | NA | |||||||||||||
3jwo | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2009-12-29 | LYS | B:167 | C:1166 | 145.0 | 0.725 | E | -117.2 | 175.7 | 145.0 | 0.725 | 0.0 | ||||||
4r2g | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2014-10-08 | LYS | B:167 | F:166 | 92.0 | 0.46 | E | -114.1 | 152.7 | 92.0 | 0.46 | 0.0 | ||||||
LYS | E:167 | B:166 | 87.0 | 0.435 | E | -121.9 | 147.3 | NA | NA | NA | |||||||||||||
LYS | H:167 | H:166 | 113.0 | 0.565 | E | -122.9 | 144.7 | NA | NA | NA | |||||||||||||
LYS | K:167 | L:166 | 70.0 | 0.35 | E | -129.6 | 143.4 | NA | NA | NA | |||||||||||||
5cay | 2 | P01730 | 100.0 | 7e-129 |
X-RAY |
2015-12-09 | LYS | B:167 | B:166 | 159.0 | 0.795 | -102.6 | 166.2 | 159.0 | 0.795 | 0.0 | |||||||
3o2d | 3 | P01730 | 100.0 | 3e-128 |
X-RAY |
2010-12-22 | LYS | C:166 | A:166 | 98.0 | 0.49 | E | -120.1 | 144.6 | 84.0 | 0.42 | 0.07 |
B:None:0.07 |
HOH |
5.398 |
CE |
O |
|
3cd4 | 1 | P01730 | 100.0 | 3e-128 |
X-RAY |
1993-10-31 | LYS | A:166 | A:166 | 66.0 | 0.33 | E | -83.3 | 169.5 | 25.0 | 0.125 | 0.205 |
A:P01730:0.205 |
HOH |
3.352 |
CD |
O |
|
3lqa | 1 | P01730 | 100.0 | 4e-128 |
X-RAY |
2010-04-07 | LYS | A:166 | C:166 | 103.0 | 0.515 | E | -126.3 | 147.1 | 103.0 | 0.515 | 0.0 | ||||||
5thr | 3 | P01730 | 100.0 | 4e-128 |
EM |
2016-11-16 | LYS | G:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | H:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | I:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6cm3 | 3 | P01730 | 100.0 | 4e-128 |
EM |
2018-10-17 | LYS | G:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | H:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | I:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6u0l | 2 | P01730 | 100.0 | 4e-128 |
EM |
2019-12-11 | LYS | D:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | E:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | F:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6u0n | 2 | P01730 | 100.0 | 4e-128 |
EM |
2019-12-11 | LYS | D:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | E:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | F:166 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
2b4c | 2 | P01730 | 100.0 | 2e-127 |
X-RAY |
2005-11-15 | LYS | B:166 | C:166 | 101.0 | 0.505 | E | -124.3 | 138.1 | 101.0 | 0.505 | 0.0 | ||||||
2qad | 2 | P01730 | 100.0 | 2e-127 |
X-RAY |
2007-09-25 | LYS | B:166 | B:166 | 97.0 | 0.485 | -132.3 | 141.9 | 97.0 | 0.485 | 0.0 |
MLA |
3.025 |
CE |
O3B |
|||
LYS | F:166 | F:166 | 80.0 | 0.4 | -133.4 | 142.0 | NA | NA | NA | ||||||||||||||
5a7x | 2 | P01730 | 100.0 | 2e-127 |
EM |
2015-08-05 | LYS | B:166 | B:166 | 78.0 | 0.39 | E | -113.8 | 167.8 | 78.0 | 0.39 | 0.0 | ||||||
LYS | F:166 | F:166 | 75.0 | 0.375 | E | -113.7 | 167.7 | 75.0 | 0.375 | 0.0 | |||||||||||||
LYS | J:166 | J:166 | 76.0 | 0.38 | E | -113.8 | 167.8 | 76.0 | 0.38 | 0.0 | |||||||||||||
4p9h | 1 | P01730 | 99.45 | 3e-127 |
X-RAY |
2014-05-21 | LYS | A:166 | C:166 | 32.0 | NA | E | -130.2 | 125.5 | 32.0 | NA | NA | ||||||
6opn | 3 | P01730 | 98.37 | 8e-126 |
EM |
2020-10-21 | LYS | C:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | F:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | I:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6opo | 4 | P01730 | 98.37 | 8e-126 |
EM |
2020-10-21 | LYS | D:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | I:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | N:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6opp | 4 | P01730 | 98.37 | 8e-126 |
EM |
2020-10-21 | LYS | D:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | M:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | O:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6opq | 4 | P01730 | 98.37 | 8e-126 |
EM |
2020-10-21 | LYS | D:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | I:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | N:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6x5b | 4 | P01730 | 98.37 | 8e-126 |
EM |
2020-10-21 | LYS | D:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | I:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | N:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
6x5c | 3 | P01730 | 98.37 | 8e-126 |
EM |
2020-10-21 | LYS | C:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LYS | F:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LYS | I:186 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
1cdi | 1 | P01730 | 100.0 | 6e-125 |
X-RAY |
1994-04-30 | LYS | A:167 | A:166 | 78.0 | 0.39 | -54.2 | 134.1 | 27.0 | 0.135 | 0.255 |
A:P01730:0.255 |
||||||
1cdh | 1 | P01730 | 100.0 | 7e-125 |
X-RAY |
1994-04-30 | LYS | A:166 | A:166 | 84.0 | 0.42 | -62.7 | 168.2 | 15.0 | 0.075 | 0.345 |
A:P01730:0.345 |
HOH |
4.945 |
CD |
O |
||
1cdj | 1 | P01730 | 100.0 | 7e-125 |
X-RAY |
1997-04-01 | LYS | A:166 | A:166 | 100.0 | 0.5 | E | -178.3 | 150.5 | 100.0 | 0.5 | 0.0 |
HOH |
3.881 |
C |
O |
||
1jl4 | 4 | P01730 | 100.0 | 7e-125 |
X-RAY |
2001-09-19 | LYS | D:166 | D:166 | 73.0 | 0.365 | E | -83.3 | 169.6 | 73.0 | 0.365 | 0.0 | ||||||
4r4h | 2 | P01730 | 100.0 | 7e-125 |
X-RAY |
2014-09-17 | LYS | B:166 | B:166 | 93.0 | 0.465 | E | -77.1 | 168.4 | 93.0 | 0.465 | 0.0 | ||||||
6l1y | 2 | P01730 | 100.0 | 4e-124 |
X-RAY |
2020-05-20 | LYS | B:166 | C:166 | 118.0 | 0.59 | 71.6 | 118.5 | 118.0 | 0.59 | 0.0 |
HOH |
6.558 |
NZ |
O |
|||
1cdy | 1 | P01730 | 99.44 | 6e-124 |
X-RAY |
1997-04-01 | LYS | A:166 | A:166 | 92.0 | 0.46 | E | -91.7 | 163.1 | 92.0 | 0.46 | 0.0 |
HOH |
3.552 |
CD |
O |
||
1cdu | 1 | P01730 | 99.44 | 8e-124 |
X-RAY |
1997-04-01 | LYS | A:166 | A:166 | 84.0 | 0.42 | E | -95.0 | 172.0 | 84.0 | 0.42 | 0.0 |
HOH |
4.601 |
NZ |
O |
||
6meo | 2 | P01730 | 100.0 | 2e-123 |
EM |
2018-12-12 | LYS | B:166 | A:166 | 96.0 | 0.48 | B | -130.9 | 143.2 | 96.0 | 0.48 | 0.0 | ||||||
3jcb | 4 | P01730 | 100.0 | 7e-123 |
EM |
2017-05-10 | LYS | D:166 | D:166 | 101.0 | 0.505 | E | -124.3 | 138.1 | 101.0 | 0.505 | 0.0 | ||||||
3jcc | 4 | P01730 | 100.0 | 7e-123 |
EM |
2017-05-10 | LYS | D:166 | D:166 | 115.0 | 0.575 | E | -116.6 | 154.7 | 115.0 | 0.575 | 0.0 | ||||||
3s4s | 4 | P01730 | 98.88 | 9e-123 |
X-RAY |
2011-09-21 | LYS | D:170 | G:166 | 85.0 | 0.425 | E | -109.5 | 161.2 | 85.0 | 0.425 | 0.0 | ||||||
LYS | H:170 | H:166 | 90.0 | 0.45 | E | -121.5 | 152.6 | NA | NA | NA | |||||||||||||
3s5l | 4 | P01730 | 97.74 | 3e-119 |
X-RAY |
2011-09-21 | LYS | G:170 | G:166 | 106.0 | 0.53 | E | -130.1 | 159.0 | 106.0 | 0.53 | 0.0 |
HOH |
6.905 |
O |
O |
||
LYS | H:170 | H:166 | 85.0 | 0.425 | E | -101.4 | 152.2 | NA | NA | NA | |||||||||||||
6tyb | 2 | F6XGD3 | 87.64 | 3e-101 |
X-RAY |
2019-10-02 | LYS | B:166 | C:166 | 79.0 | 0.395 | E | -104.2 | 156.8 | 79.0 | 0.395 | 0.0 |
HOH |
6.768 |
NZ |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p01730-f1 | 1 | P01730 | 100.0 | 0.0 | LYS | A:191 | A:191 | 111.0 | 0.555 | E | -95.3 | 154.2 |