Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79693245 . G A CCDS9017.1:NM_001135805.1:c.724Gga>Aga_NP_001129277.1:p.242G>R Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 GLY F:102 F:241 9.0 0.12 E -108.5 134.4 9.0 0.12 0.0
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 GLY E:101 E:241 2.0 0.027 E 178.6 140.3 2.0 0.027 0.0
GLY F:101 F:241 0.0 0.0 E 176.7 140.6 0.0 0.0 0.0
GLY K:101 K:241 1.0 0.013 E 177.1 140.2 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 GLY E:101 E:241 1.0 0.013 E 165.6 165.1 1.0 0.013 0.0
GLY F:101 F:241 3.0 0.04 E -176.8 175.3 3.0 0.04 0.0
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 GLY E:101 E:241 0.0 0.0 E -153.9 -177.4 0.0 0.0 0.0
GLY F:101 F:241 2.0 0.027 E -153.1 -178.7 2.0 0.027 0.0
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 GLY B:101 2:241 0.0 0.0 E -154.0 -177.4 0.0 0.0 0.0
GLY C:101 3:241 0.0 0.0 E -153.9 -177.4 0.0 0.0 0.0
GLY D:101 4:241 0.0 0.0 E -153.9 -177.4 0.0 0.0 0.0
GLY E:101 5:241 0.0 0.0 E -153.8 -177.3 0.0 0.0 0.0
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 GLY A:104 A:241 0.0 0.0 E 176.6 171.0 0.0 0.0 0.0
GLY B:104 B:241 0.0 0.0 E -175.3 172.1 0.0 0.0 0.0
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 GLY E:101 E:241 3.0 0.04 E -178.9 138.0 3.0 0.04 0.0
GLY F:101 F:241 0.0 0.0 E -178.1 140.5 NA NA NA
GLY K:101 K:241 1.0 0.013 E -178.6 138.5 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 GLY E:101 E:241 5.0 0.067 E 175.0 142.8 5.0 0.067 0.0
GLY F:101 F:241 0.0 0.0 E 176.0 143.7 NA NA NA
GLY K:101 K:241 3.0 0.04 E 175.2 143.2 NA NA NA
2k8m 1 Q6AI31 100.0 2e-89 NMR
 2009-03-17 GLY A:102 A:102 0.0 0.0 E 174.3 164.8 0.0 0.0 0.0
GLY D:102 D:102 0.0 0.0 E -169.6 174.7 0.0 0.0 0.0
2ki6 1 P21579 100.0 2e-89 NMR
 2010-03-09 GLY A:102 A:102 0.0 0.0 E 171.3 179.5 0.0 0.0 0.0
GLY F:102 F:102 0.0 0.0 E 171.7 179.5 0.0 0.0 0.0
6mti 1 P21707 100.0 1e-88 EM
 2019-04-24 GLY A:101 1:241 1.0 0.013 E -153.9 -177.4 1.0 0.013 0.0
GLY F:101 6:241 0.0 0.0 E -153.9 -177.4 0.0 0.0 0.0
4wee 1 P21707 100.0 1e-88 X-RAY
 2014-10-01 GLY A:119 A:241 0.0 0.0 E -179.9 180.0 0.0 0.0 0.0 NA
NA
NA
HOH
 5.979
6.192
8.923
3.151
 HA3
HA3
HA3
HA2
 NA
NA
NA
O
5t0r 1 P46096 100.0 6e-88 X-RAY
 2017-06-14 GLY A:102 A:241 0.0 0.0 E -174.2 164.0 0.0 0.0 0.0 HOH
 3.974
 CA
 O
5vfe 1 P46096 100.0 6e-88 X-RAY
 2018-04-11 GLY A:102 A:241 0.0 0.0 E -179.8 172.5 0.0 0.0 0.0 HOH
 4.980
 N
 O
GLY B:102 B:241 2.0 0.027 E 179.6 168.4 NA NA NA
3f00 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 GLY A:119 A:241 0.0 0.0 E -174.8 173.7 0.0 0.0 0.0 HOH
 3.901
 CA
 O
3f01 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 GLY A:119 A:241 0.0 0.0 E -178.5 173.1 0.0 0.0 0.0 HOH
 3.933
 CA
 O
3f04 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 GLY A:119 A:241 0.0 0.0 E -178.1 173.2 0.0 0.0 0.0 HOH
 3.941
 CA
 O
3f05 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 GLY A:119 A:241 0.0 0.0 E -179.5 173.4 0.0 0.0 0.0 HOH
 4.156
 CA
 O
1rsy 1 P21707 100.0 3e-87 X-RAY
 1995-05-08 GLY A:127 A:241 0.0 0.0 E -177.5 171.0 0.0 0.0 0.0 HOH
 3.863
 CA
 O
6cxw 1 P21707 87.5 5e-71 X-RAY
 2019-04-17 GLY A:104 A:243 0.0 0.0 E -177.0 170.7 0.0 0.0 0.0 HOH
 6.326
 HA2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 GLY A:242 A:242 0.0 0.0 E 177.7 167.8