Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79842725 . G A CCDS9017.1:NM_001135805.1:c.1090Gac>Aac_NP_001129277.1:p.364D>N Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 ASP F:224 F:363 0.0 0.0 E -102.0 116.9 0.0 0.0 0.0 GOL
HOH
 6.715
2.704
 OD2
OD2
 O1
O
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASP E:223 E:363 0.0 0.0 E -108.0 134.1 0.0 0.0 0.0 CA
CA
 3.117
3.249
 OD2
OD2
 CA
CA
ASP F:223 F:363 0.0 0.0 E -110.2 135.1 0.0 0.0 0.0 CA
 4.533
 OD2
 CA
ASP K:223 K:363 0.0 0.0 E -106.9 134.9 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASP E:223 E:363 0.0 0.0 E -110.1 111.6 0.0 0.0 0.0 CA
CA
 2.909
2.921
 OD1
OD2
 CA
CA
ASP F:223 F:363 22.0 0.147 E -98.2 120.2 22.0 0.147 0.0 CA
CA
 4.323
2.509
 OD1
OD2
 CA
CA
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASP E:223 E:363 4.0 0.027 E -102.3 146.0 4.0 0.027 0.0 MG
 2.738
 OD2
 MG
ASP F:223 F:363 3.0 0.02 E -102.0 145.6 3.0 0.02 0.0 MG
 2.290
 OD2
 MG
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 ASP B:223 2:644 4.0 0.027 E -102.3 145.9 4.0 0.027 0.0 MG
 2.739
 OD2
 MG
ASP C:223 3:644 3.0 0.02 E -102.3 146.0 3.0 0.02 0.0 MG
 2.740
 OD2
 MG
ASP D:223 4:644 4.0 0.027 E -102.4 146.0 4.0 0.027 0.0 MG
 2.740
 OD2
 MG
ASP E:223 5:644 4.0 0.027 E -102.3 146.0 4.0 0.027 0.0 MG
 2.738
 OD2
 MG
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 ASP A:226 A:363 2.0 0.013 E -99.8 126.0 2.0 0.013 0.0 HOH
 2.456
 OD1
 O
ASP B:226 B:363 3.0 0.02 E -100.8 126.5 3.0 0.02 0.0 HOH
 2.864
 OD1
 O
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 ASP E:223 E:363 0.0 0.0 E -109.2 133.9 0.0 0.0 0.0 CA
CA
 3.180
3.342
 OD2
OD2
 CA
CA
ASP F:223 F:363 0.0 0.0 E -113.8 137.5 NA NA NA
ASP K:223 K:363 0.0 0.0 E -107.8 135.3 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 ASP E:223 E:363 0.0 0.0 E -109.5 131.5 0.0 0.0 0.0 CA
CA
 2.460
2.700
 OD2
OD2
 CA
CA
ASP F:223 F:363 0.0 0.0 E -111.6 132.9 NA NA NA
ASP K:223 K:363 0.0 0.0 E -109.8 130.6 NA NA NA
2lha 1 P21579 100.0 4e-96 NMR
 2012-05-02 ASP A:94 A:363 1.0 0.007 E -143.3 145.2 1.0 0.007 0.0 IHP
 6.483
 O
 O33
5w5d 6 P21707 100.0 4e-96 X-RAY
 2017-08-23 ASP F:94 F:363 7.0 0.047 E -99.1 108.9 7.0 0.047 0.0 HOH
 2.971
 OD2
 O
5t0s 1 P46096 100.0 2e-95 X-RAY
 2017-06-14 ASP A:93 A:363 3.0 0.02 E -96.6 120.8 3.0 0.02 0.0 CD
HOH
 2.480
2.555
 OD1
OD2
 CD
O
2yoa 1 P21707 100.0 3e-95 X-RAY
 2013-03-20 ASP A:94 A:363 0.0 0.0 E -97.8 116.0 0.0 0.0 0.0 CA
CA
CA
SEP
CA
SCN
HOH
 2.365
2.316
5.622
4.691
6.687
7.080
4.590
 OD1
OD2
OD2
OD1
OD1
C
OD2
 CA
CA
CA
O
CA
S
O
ASP B:94 B:363 0.0 0.0 E -100.8 117.0 NA NA NA
6tz3 1 P21579 100.0 3e-95 X-RAY
 2020-05-13 ASP A:99 A:364 0.0 0.0 E -97.2 121.4 0.0 0.0 0.0 SO4
HOH
 7.331
2.676
 O
OD2
 O4
O
1tjm 1 P21707 100.0 4e-95 X-RAY
 2004-09-28 ASP A:101 A:363 11.0 0.073 E -93.7 121.2 11.0 0.073 0.0 SR
HOH
 2.431
1.942
 OD2
HA
 SR
H2
1tjx 1 P21707 100.0 4e-95 X-RAY
 2004-11-23 ASP A:101 A:363 0.0 0.0 E -95.4 120.7 0.0 0.0 0.0 CA
CA
HOH
 2.431
2.479
1.895
 OD1
OD2
O
 CA
CA
H1
1uov 1 P21707 100.0 4e-95 X-RAY
 2004-09-09 ASP A:101 A:363 1.0 0.007 E -93.4 119.8 1.0 0.007 0.0 CA
CA
CA
HOH
 2.348
2.496
5.708
2.710
 OD2
OD1
OD1
O
 CA
CA
CA
O
1uow 1 P21707 100.0 4e-95 X-RAY
 2004-09-16 ASP A:101 A:363 0.0 0.0 E -95.1 120.3 0.0 0.0 0.0 CA
CA
HOH
 2.436
2.521
2.751
 OD1
OD2
O
 CA
CA
O
4v11 1 P21579 100.0 2e-94 X-RAY
 2015-02-25 ASP A:92 A:364 0.0 0.0 E -95.5 111.9 0.0 0.0 0.0 CA
CA
HOH
 2.367
2.303
2.993
 OD1
OD2
O
 CA
CA
O
6u4w 1 P21579 99.34 2e-94 X-RAY
 2020-05-13 ASP A:99 A:364 1.0 0.007 E -98.9 117.5 1.0 0.007 0.0 SO4
HOH
 6.960
2.322
 O
OD2
 O1
O
6u4u 1 P21579 99.34 2e-94 X-RAY
 2020-05-13 ASP A:99 A:364 0.0 0.0 E -98.9 120.4 0.0 0.0 0.0 SO4
HOH
 7.004
2.424
 O
OD2
 O4
O
6u41 1 P21579 99.34 3e-94 X-RAY
 2020-05-13 ASP A:99 A:364 7.0 0.047 E -96.2 118.3 7.0 0.047 0.0 SO4
HOH
 7.629
2.447
 O
OD2
 O4
O
5vff 1 P46096 99.34 5e-94 X-RAY
 2018-04-11 ASP A:93 A:363 8.0 0.053 E -98.4 113.6 8.0 0.053 0.0 PB
HOH
 2.581
2.297
 OD2
OD1
 PB
O
5vfg 1 P46096 99.34 5e-94 X-RAY
 2018-04-11 ASP A:93 A:363 1.0 0.007 E -94.8 127.7 1.0 0.007 0.0 PB
HOH
 2.497
3.091
 OD2
O
 PB
O
2n1t 5 P21579 100.0 3e-93 NMR
 2015-06-03 ASP E:101 E:363 16.0 0.107 -98.6 152.4 16.0 0.107 0.0
5ccj 1 P21707 96.69 7e-91 X-RAY
 2015-08-12 ASP A:94 A:363 5.0 0.033 E -92.9 127.6 5.0 0.033 0.0 GOL
SO4
SO4
HOH
 7.301
7.384
9.677
2.686
 O
O
OD2
OD2
 C1
O3
O3
O
ASP B:94 B:363 1.0 0.007 E -94.2 115.7 NA NA NA
ASP C:94 C:363 9.0 0.06 E -101.6 122.2 NA NA NA
ASP D:94 D:363 14.0 0.093 E -97.2 127.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 ASP A:364 A:364 0.0 0.0 E -87.5 144.5