Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79842748 . C A CCDS9017.1:NM_001135805.1:c.1113aaC>aaA_NP_001129277.1:p.371N>K Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 ASN F:231 F:370 110.0 0.688 S -67.3 106.6 110.0 0.688 0.0 HOH
 2.548
 OD1
 O
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASN E:230 E:370 53.0 0.331 -70.4 111.7 53.0 0.331 0.0 CA
CA
 6.680
6.859
 OD1
C
 CA
CA
ASN F:230 F:370 60.0 0.375 -67.5 113.4 60.0 0.375 0.0 CA
 7.154
 OD1
 CA
ASN K:230 K:370 56.0 0.35 -70.5 114.9 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASN E:230 E:370 57.0 0.356 -85.5 118.5 57.0 0.356 0.0 CA
CA
 7.165
7.341
 OD1
CA
 CA
CA
ASN F:230 F:370 152.0 0.95 360.0 116.6 152.0 0.95 0.0 CA
CA
 9.583
9.429
 OD1
C
 CA
CA
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASN E:230 E:370 62.0 0.388 -89.4 116.6 62.0 0.388 0.0 MG
 7.168
 OD1
 MG
ASN F:230 F:370 118.0 0.738 -78.0 113.0 118.0 0.738 0.0 MG
 8.448
 C
 MG
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 ASN B:230 2:651 61.0 0.381 -89.4 116.6 61.0 0.381 0.0 MG
 7.169
 OD1
 MG
ASN C:230 3:651 62.0 0.388 -89.5 116.6 62.0 0.388 0.0 MG
 7.168
 OD1
 MG
ASN D:230 4:651 63.0 0.394 -89.4 116.6 63.0 0.394 0.0 MG
 7.168
 OD1
 MG
ASN E:230 5:651 62.0 0.388 -89.4 116.6 62.0 0.388 0.0 MG
 7.168
 OD1
 MG
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 ASN A:233 A:370 42.0 0.263 -90.2 103.4 42.0 0.263 0.0 HOH
 3.113
 ND2
 O
ASN B:233 B:370 43.0 0.269 -90.3 103.7 43.0 0.269 0.0 HOH
 6.741
 ND2
 O
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 ASN E:230 E:370 54.0 0.338 -72.8 113.6 54.0 0.338 0.0 CA
CA
 6.917
6.814
 OD1
C
 CA
CA
ASN F:230 F:370 61.0 0.381 -67.1 121.2 NA NA NA
ASN K:230 K:370 60.0 0.375 -73.7 117.0 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 ASN E:230 E:370 48.0 0.3 -70.3 119.4 48.0 0.3 0.0 CA
CA
 6.835
6.985
 OD1
C
 CA
CA
ASN F:230 F:370 62.0 0.388 -69.0 119.3 NA NA NA
ASN K:230 K:370 55.0 0.344 -71.5 120.2 NA NA NA
2lha 1 P21579 100.0 4e-96 NMR
 2012-05-02 ASN A:101 A:370 41.0 0.256 B -152.6 166.5 41.0 0.256 0.0 IHP
 6.524
 H
 O23
5w5d 6 P21707 100.0 4e-96 X-RAY
 2017-08-23 ASN F:101 F:370 87.0 0.544 S -66.3 105.4 87.0 0.544 0.0 HOH
 2.819
 OD1
 O
5t0s 1 P46096 100.0 2e-95 X-RAY
 2017-06-14 ASN A:100 A:370 89.0 0.556 -92.7 112.5 89.0 0.556 0.0 HOH
 2.967
 O
 O
2yoa 1 P21707 100.0 3e-95 X-RAY
 2013-03-20 ASN A:101 A:370 40.0 0.25 -70.3 155.2 40.0 0.25 0.0 CA
CA
CA
SEP
CA
SCN
HOH
 6.784
6.234
4.456
7.418
8.503
3.778
2.992
 OD1
C
C
OD1
OD1
ND2
ND2
 CA
CA
CA
O
CA
S
O
ASN B:101 B:370 38.0 0.237 -68.8 153.0 NA NA NA
6tz3 1 P21579 100.0 3e-95 X-RAY
 2020-05-13 ASN A:106 A:371 32.0 0.2 -71.5 126.5 32.0 0.2 0.0 SO4
SO4
HOH
 2.901
8.467
1.917
 HD22
HD22
H
 O4
O1
O
1tjm 1 P21707 100.0 4e-95 X-RAY
 2004-09-28 ASN A:108 A:370 33.0 0.206 -73.4 130.4 33.0 0.206 0.0 SR
HOH
 7.116
2.145
 HA
HA
 SR
H2
1tjx 1 P21707 100.0 4e-95 X-RAY
 2004-11-23 ASN A:108 A:370 40.0 0.25 -76.8 121.9 40.0 0.25 0.0 CA
CA
ACT
HOH
 6.189
6.624
7.985
1.632
 HA
HD22
HB2
HD21
 CA
CA
H1
H1
1uov 1 P21707 100.0 4e-95 X-RAY
 2004-09-09 ASN A:108 A:370 41.0 0.256 -83.0 114.8 41.0 0.256 0.0 CA
CA
HOH
 7.085
7.042
2.382
 CA
OD1
OD1
 CA
CA
O
1uow 1 P21707 100.0 4e-95 X-RAY
 2004-09-16 ASN A:108 A:370 40.0 0.25 -76.6 121.6 40.0 0.25 0.0 CA
CA
ACT
HOH
 7.114
7.026
8.800
2.324
 CA
ND2
O
ND2
 CA
CA
O
O
4v11 1 P21579 100.0 2e-94 X-RAY
 2015-02-25 ASN A:99 A:371 46.0 0.287 -72.9 98.7 46.0 0.287 0.0 CA
CA
HOH
 6.761
6.274
2.923
 OD1
CA
N
 CA
CA
O
6u4w 1 P21579 99.34 2e-94 X-RAY
 2020-05-13 ASN A:106 A:371 32.0 0.2 -74.5 129.4 32.0 0.2 0.0 SO4
SO4
HOH
 8.259
2.780
1.861
 HB2
HB2
H
 O2
O1
O
6u4u 1 P21579 99.34 2e-94 X-RAY
 2020-05-13 ASN A:106 A:371 34.0 0.212 -75.8 123.9 34.0 0.212 0.0 SO4
SO4
HOH
 2.823
8.564
1.942
 HD22
HB2
H
 O4
O2
O
6u41 1 P21579 99.34 3e-94 X-RAY
 2020-05-13 ASN A:106 A:371 29.0 0.181 -74.2 129.2 29.0 0.181 0.0 SO4
SO4
HOH
 2.882
8.336
1.961
 HD22
HD22
H
 O4
O2
O
5vff 1 P46096 99.34 5e-94 X-RAY
 2018-04-11 ASN A:100 A:370 51.0 0.319 -87.5 113.0 51.0 0.319 0.0 PB
HOH
 7.173
2.274
 OD1
OD1
 PB
O
5vfg 1 P46096 99.34 5e-94 X-RAY
 2018-04-11 ASN A:100 A:370 39.0 0.244 -79.0 122.8 39.0 0.244 0.0 PB
HOH
 7.129
2.252
 OD1
OD1
 PB
O
2n1t 5 P21579 100.0 3e-93 NMR
 2015-06-03 ASN E:108 E:370 64.0 0.4 -59.6 138.2 64.0 0.4 0.0
5ccj 1 P21707 96.69 7e-91 X-RAY
 2015-08-12 ASN A:101 A:370 70.0 0.438 -99.0 106.8 70.0 0.438 0.0 GOL
SO4
SO4
HOH
 3.831
9.053
3.004
2.757
 ND2
ND2
ND2
OD1
 O1
O4
O3
O
ASN B:101 B:370 48.0 0.3 -94.4 112.6 NA NA NA
ASN C:101 C:370 44.0 0.275 -75.1 141.3 NA NA NA
ASN D:101 D:370 46.0 0.287 -58.0 138.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 ASN A:371 A:371 38.0 0.237 -54.7 124.5