Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 109994886 | . | G | A | CCDS9131.1:NM_052845.3:c.700Caa>Taa_NP_443077.1:p.234Q>* | Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2idx | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2007-02-06 | GLN | A:180 | A:234 | 167.0 | 0.928 | 65.4 | 102.9 | 167.0 | 0.928 | 0.0 |
HOH |
7.414 |
C |
O |
|||
| GLN | B:180 | B:234 | 135.0 | 0.75 | -58.9 | 129.6 | 135.0 | 0.75 | 0.0 |
HOH |
2.643 |
NE2 |
O |
||||||||||
| GLN | C:180 | C:234 | 145.0 | 0.806 | -90.9 | 127.7 | 145.0 | 0.806 | 0.0 |
HOH |
5.500 |
NE2 |
O |
||||||||||
| 6d5k | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | GLN | A:180 | A:234 | 146.0 | 0.811 | -50.6 | -62.5 | 146.0 | 0.811 | 0.0 |
HOH |
7.266 |
O |
O |
|||
| GLN | B:180 | B:234 | 158.0 | 0.878 | -106.2 | 131.0 | 158.0 | 0.878 | 0.0 | ||||||||||||||
| GLN | C:180 | C:234 | 138.0 | 0.767 | -109.7 | 121.2 | 138.0 | 0.767 | 0.0 | ||||||||||||||
| 6d5x | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | GLN | A:180 | A:234 | 148.0 | 0.822 | -86.0 | 134.5 | 148.0 | 0.822 | 0.0 |
HOH |
6.607 |
O |
O |
|||
| GLN | B:180 | B:234 | 170.0 | 0.944 | -97.4 | 138.1 | 170.0 | 0.944 | 0.0 | ||||||||||||||
| GLN | C:180 | C:234 | 164.0 | 0.911 | -95.2 | 131.6 | 164.0 | 0.911 | 0.0 | ||||||||||||||
| 7ruv | 1 | Q96EY8 | 98.98 | 2e-144 |
X-RAY |
2021-11-24 | GLN | A:180 | A:234 | 143.0 | 0.794 | -85.7 | 141.3 | 143.0 | 0.794 | 0.0 |
HOH |
4.002 |
OE1 |
O |
|||
| GLN | B:180 | B:234 | 80.0 | NA | -76.7 | 141.5 | NA | NA | NA | ||||||||||||||
| GLN | C:180 | C:234 | 151.0 | 0.839 | -74.0 | 140.0 | NA | NA | NA | ||||||||||||||
| GLN | D:180 | D:234 | 179.0 | 0.994 | -79.7 | 152.7 | NA | NA | NA | ||||||||||||||
| 7rut | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | GLN | A:180 | E:234 | 160.0 | 0.889 | -93.0 | 114.9 | 160.0 | 0.889 | 0.0 |
HOH |
2.769 |
O |
O |
|||
| GLN | B:180 | C:234 | 153.0 | 0.85 | -82.2 | 117.2 | NA | NA | NA | ||||||||||||||
| GLN | C:180 | F:234 | 89.0 | NA | -76.3 | 126.4 | NA | NA | NA | ||||||||||||||
| GLN | D:180 | B:234 | 89.0 | NA | -75.7 | 134.2 | NA | NA | NA | ||||||||||||||
| GLN | E:180 | A:234 | 90.0 | NA | -75.8 | 148.2 | NA | NA | NA | ||||||||||||||
| GLN | F:180 | D:234 | 89.0 | NA | -80.3 | 125.6 | 89.0 | NA | NA |
HOH |
2.784 |
O |
O |
||||||||||
| 7ruu | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | GLN | A:180 | A:234 | 170.0 | 0.944 | -79.0 | 137.3 | 170.0 | 0.944 | 0.0 |
HOH |
4.313 |
C |
O |
|||
| GLN | B:180 | B:234 | 176.0 | 0.978 | -76.0 | 138.9 | NA | NA | NA | ||||||||||||||
| GLN | C:180 | C:234 | 80.0 | NA | -69.7 | 144.6 | NA | NA | NA | ||||||||||||||
| GLN | D:180 | D:234 | 167.0 | 0.928 | -71.0 | 145.2 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q96ey8-f1 | 1 | Q96EY8 | 100.0 | 0.0 | GLN | A:234 | A:234 | 180.0 | 1.0 | -87.2 | 132.0 | ||