Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 109996920 | . | C | A | CCDS9131.1:NM_052845.3:c.625Gtg>Ttg_NP_443077.1:p.209V>L | Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2idx | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2007-02-06 | VAL | A:155 | A:209 | 0.0 | 0.0 | H | -60.4 | -40.7 | 0.0 | 0.0 | 0.0 |
HOH |
8.170 |
O |
O |
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| VAL | B:155 | B:209 | 0.0 | 0.0 | H | -73.8 | -43.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.005 |
CG2 |
O |
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| VAL | C:155 | C:209 | 0.0 | 0.0 | H | -58.3 | -46.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.885 |
CG2 |
O |
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| 6d5k | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | VAL | A:155 | A:209 | 0.0 | 0.0 | H | -70.5 | -48.4 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:155 | B:209 | 0.0 | 0.0 | H | -64.1 | -46.7 | 0.0 | 0.0 | 0.0 |
SO4 |
9.878 |
C |
O1 |
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| VAL | C:155 | C:209 | 0.0 | 0.0 | H | -67.8 | -48.4 | 0.0 | 0.0 | 0.0 |
SO4 |
8.433 |
N |
O2 |
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| 6d5x | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | VAL | A:155 | A:209 | 0.0 | 0.0 | H | -60.9 | -48.1 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:155 | B:209 | 1.0 | 0.006 | H | -65.0 | -48.0 | 1.0 | 0.006 | 0.0 |
HOH |
4.530 |
CG2 |
O |
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| VAL | C:155 | C:209 | 0.0 | 0.0 | H | -65.3 | -47.9 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
8.077 6.769 |
N C |
O2 O |
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| 7ruv | 1 | Q96EY8 | 98.98 | 2e-144 |
X-RAY |
2021-11-24 | VAL | A:155 | A:209 | 0.0 | 0.0 | H | -55.4 | -51.5 | 0.0 | 0.0 | 0.0 |
HOH |
8.690 |
C |
O |
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| VAL | B:155 | B:209 | 0.0 | 0.0 | H | -59.1 | -49.2 | NA | NA | NA | |||||||||||||
| VAL | C:155 | C:209 | 0.0 | 0.0 | H | -64.7 | -44.2 | NA | NA | NA | |||||||||||||
| VAL | D:155 | D:209 | 0.0 | 0.0 | H | -61.1 | -47.4 | NA | NA | NA | |||||||||||||
| 7rut | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | VAL | A:155 | E:209 | 0.0 | 0.0 | H | -66.2 | -44.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.362 |
CG2 |
O |
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| VAL | B:155 | C:209 | 0.0 | 0.0 | H | -65.4 | -45.6 | NA | NA | NA | |||||||||||||
| VAL | C:155 | F:209 | 0.0 | 0.0 | H | -61.5 | -46.4 | NA | NA | NA | |||||||||||||
| VAL | D:155 | B:209 | 0.0 | 0.0 | H | -61.1 | -47.5 | NA | NA | NA | |||||||||||||
| VAL | E:155 | A:209 | 0.0 | 0.0 | H | -61.2 | -47.6 | NA | NA | NA | |||||||||||||
| VAL | F:155 | D:209 | 0.0 | 0.0 | H | -63.1 | -45.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.356 |
CG2 |
O |
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| 7ruu | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | VAL | A:155 | A:209 | 0.0 | 0.0 | H | -65.0 | -45.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.127 |
CG2 |
O |
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| VAL | B:155 | B:209 | 0.0 | 0.0 | H | -66.4 | -49.4 | NA | NA | NA | |||||||||||||
| VAL | C:155 | C:209 | 0.0 | 0.0 | H | -67.3 | -46.0 | NA | NA | NA | |||||||||||||
| VAL | D:155 | D:209 | 0.0 | 0.0 | H | -62.3 | -47.9 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q96ey8-f1 | 1 | Q96EY8 | 100.0 | 0.0 | VAL | A:209 | A:209 | 0.0 | 0.0 | H | -63.3 | -48.0 | |