Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 109999242 . T A CCDS9131.1:NM_052845.3:c.502Acg>Tcg_NP_443077.1:p.168T>S Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2idx 1 Q96EY8 99.49 4e-145 X-RAY
 2007-02-06 THR A:114 A:168 138.0 0.986 -97.7 -34.5 138.0 0.986 0.0
THR B:114 B:168 154.0 1.0 -116.7 -16.5 154.0 1.0 0.0 HOH
 5.561
 O
 O
THR C:114 C:168 149.0 1.0 -144.0 -20.2 149.0 1.0 0.0 HOH
 7.198
 N
 O
6d5k 1 Q96EY8 99.49 4e-145 X-RAY
 2018-10-10 THR A:114 A:168 141.0 1.0 -130.6 -0.5 141.0 1.0 0.0 B12
 3.037
 O
 O7R
THR B:114 B:168 148.0 1.0 -113.3 -23.5 148.0 1.0 0.0 B12
HOH
 3.034
5.922
 O
O
 O7R
O
THR C:114 C:168 142.0 1.0 -135.3 -2.7 142.0 1.0 0.0
6d5x 1 Q96EY8 99.49 4e-145 X-RAY
 2018-10-10 THR A:114 A:168 148.0 1.0 -120.5 -2.8 148.0 1.0 0.0 B12
HOH
 3.135
3.411
 O
OG1
 C2B
O
THR B:114 B:168 143.0 1.0 -112.7 -25.7 143.0 1.0 0.0 B12
HOH
 3.199
6.233
 O
O
 O7R
O
THR C:114 C:168 140.0 1.0 -115.2 -28.9 140.0 1.0 0.0
7ruv 1 Q96EY8 98.98 2e-144 X-RAY
 2021-11-24 THR A:114 A:168 152.0 1.0 -124.6 23.8 152.0 1.0 0.0 B12
HOH
 2.410
3.122
 O
N
 O7R
O
THR B:114 B:168 147.0 1.0 -125.1 32.8 NA NA NA
THR C:114 C:168 149.0 1.0 -131.1 27.1 NA NA NA
THR D:114 D:168 149.0 1.0 -122.6 20.6 NA NA NA
7rut 1 Q96EY8 98.98 2e-143 X-RAY
 2021-11-24 THR A:114 E:168 139.0 0.993 -106.5 -41.6 139.0 0.993 0.0 HOH
 6.447
 O
 O
THR B:114 C:168 141.0 1.0 -115.9 -21.4 NA NA NA
THR C:114 F:168 154.0 1.0 S -95.5 -39.4 NA NA NA
THR D:114 B:168 99.0 NA -125.6 -9.8 NA NA NA
THR E:114 A:168 120.0 0.857 -120.8 -54.1 NA NA NA
THR F:114 D:168 54.0 0.386 -123.5 148.3 54.0 0.386 0.0 MG
ATP
HOH
 7.194
9.982
5.949
 O
O
N
 MG
O2A
O
7ruu 1 Q96EY8 98.98 2e-143 X-RAY
 2021-11-24 THR A:114 A:168 148.0 1.0 -126.4 32.9 148.0 1.0 0.0 B12
HOH
 2.689
3.066
 O
O
 O7R
O
THR B:114 B:168 147.0 1.0 -130.4 25.4 NA NA NA
THR C:114 C:168 146.0 1.0 -107.8 -2.8 NA NA NA
THR D:114 D:168 148.0 1.0 -124.3 26.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96ey8-f1 1 Q96EY8 100.0 0.0 THR A:168 A:168 131.0 0.936 -98.4 -15.2