Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 109999290 | . | C | A | CCDS9131.1:NM_052845.3:c.454Gag>Tag_NP_443077.1:p.152E>* | Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2idx | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2007-02-06 | GLU | A:98 | A:152 | 74.0 | 0.389 | H | -49.7 | -50.5 | 74.0 | 0.389 | 0.0 |
HOH |
7.642 |
N |
O |
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| GLU | B:98 | B:152 | 81.0 | 0.426 | H | -64.8 | -42.8 | 81.0 | 0.426 | 0.0 |
HOH |
5.906 |
OE2 |
O |
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| GLU | C:98 | C:152 | 57.0 | 0.3 | H | -53.6 | -52.0 | 57.0 | 0.3 | 0.0 |
HOH |
2.998 |
OE2 |
O |
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| 6d5k | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | GLU | A:98 | A:152 | 78.0 | 0.411 | H | -55.1 | -52.4 | 78.0 | 0.411 | 0.0 | ||||||
| GLU | B:98 | B:152 | 54.0 | 0.284 | H | -59.8 | -50.2 | 54.0 | 0.284 | 0.0 | |||||||||||||
| GLU | C:98 | C:152 | 62.0 | 0.326 | H | -52.3 | -51.2 | 62.0 | 0.326 | 0.0 | |||||||||||||
| 6d5x | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | GLU | A:98 | A:152 | 59.0 | 0.311 | H | -56.8 | -47.0 | 59.0 | 0.311 | 0.0 |
HOH |
3.276 |
OE1 |
O |
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| GLU | B:98 | B:152 | 77.0 | 0.405 | H | -60.5 | -46.3 | 77.0 | 0.405 | 0.0 |
HOH |
4.208 |
OE1 |
O |
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| GLU | C:98 | C:152 | 61.0 | 0.321 | H | -58.1 | -45.9 | 61.0 | 0.321 | 0.0 |
HOH |
4.049 |
OE1 |
O |
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| 7ruv | 1 | Q96EY8 | 98.98 | 2e-144 |
X-RAY |
2021-11-24 | GLU | A:98 | A:152 | 59.0 | 0.311 | H | -66.3 | -40.3 | 59.0 | 0.311 | 0.0 |
HOH |
6.584 |
OE2 |
O |
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| GLU | B:98 | B:152 | 61.0 | 0.321 | H | -60.5 | -39.6 | NA | NA | NA | |||||||||||||
| GLU | C:98 | C:152 | 87.0 | 0.458 | H | -63.4 | -42.7 | NA | NA | NA | |||||||||||||
| GLU | D:98 | D:152 | 86.0 | 0.453 | H | -63.7 | -44.9 | NA | NA | NA | |||||||||||||
| 7rut | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | GLU | A:98 | E:152 | 73.0 | 0.384 | H | -66.6 | -41.7 | 73.0 | 0.384 | 0.0 |
HOH |
5.970 |
OE2 |
O |
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| GLU | B:98 | C:152 | 76.0 | 0.4 | H | -66.2 | -40.4 | NA | NA | NA | |||||||||||||
| GLU | C:98 | F:152 | 94.0 | 0.495 | H | -67.6 | -41.0 | NA | NA | NA | |||||||||||||
| GLU | D:98 | B:152 | 58.0 | 0.305 | H | -67.0 | -38.6 | NA | NA | NA | |||||||||||||
| GLU | E:98 | A:152 | 68.0 | 0.358 | H | -66.0 | -38.3 | NA | NA | NA | |||||||||||||
| GLU | F:98 | D:152 | 82.0 | 0.432 | H | -67.8 | -40.3 | 82.0 | 0.432 | 0.0 |
HOH |
2.491 |
OE2 |
O |
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| 7ruu | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | GLU | A:98 | A:152 | 64.0 | 0.337 | H | -63.6 | -44.0 | 64.0 | 0.337 | 0.0 |
ACT HOH |
2.892 3.832 |
OE1 CA |
O O |
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| GLU | B:98 | B:152 | 92.0 | 0.484 | H | -62.2 | -45.5 | NA | NA | NA | |||||||||||||
| GLU | C:98 | C:152 | 51.0 | 0.268 | H | -64.7 | -41.3 | NA | NA | NA | |||||||||||||
| GLU | D:98 | D:152 | 86.0 | 0.453 | H | -63.4 | -42.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q96ey8-f1 | 1 | Q96EY8 | 100.0 | 0.0 | GLU | A:152 | A:152 | 52.0 | 0.274 | H | -67.8 | -41.6 | |