Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 110006578 | . | A | C | CCDS9131.1:NM_052845.3:c.287aTt>aGt_NP_443077.1:p.96I>S | Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2idx | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2007-02-06 | ILE | A:42 | A:96 | 0.0 | 0.0 | H | -69.3 | -45.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.352 |
O |
O |
||
| ILE | B:42 | B:96 | 0.0 | 0.0 | H | -55.6 | -42.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.387 |
O |
O |
|||||||||
| ILE | C:42 | C:96 | 0.0 | 0.0 | H | -56.8 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.452 |
O |
O |
|||||||||
| 6d5k | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | ILE | A:42 | A:96 | 0.0 | 0.0 | H | -60.4 | -36.8 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:42 | B:96 | 0.0 | 0.0 | H | -58.4 | -38.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| ILE | C:42 | C:96 | 0.0 | 0.0 | H | -59.0 | -37.9 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6d5x | 1 | Q96EY8 | 99.49 | 4e-145 |
X-RAY |
2018-10-10 | ILE | A:42 | A:96 | 0.0 | 0.0 | H | -65.2 | -37.2 | 0.0 | 0.0 | 0.0 |
HOH |
7.877 |
CB |
O |
||
| ILE | B:42 | B:96 | 0.0 | 0.0 | H | -63.9 | -38.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.913 |
CB |
O |
|||||||||
| ILE | C:42 | C:96 | 0.0 | 0.0 | H | -63.2 | -37.0 | 0.0 | 0.0 | 0.0 |
HOH |
9.269 |
CD1 |
O |
|||||||||
| 7ruv | 1 | Q96EY8 | 98.98 | 2e-144 |
X-RAY |
2021-11-24 | ILE | A:42 | A:96 | 0.0 | 0.0 | H | -65.5 | -36.4 | 0.0 | 0.0 | 0.0 |
HOH |
7.127 |
O |
O |
||
| ILE | B:42 | B:96 | 1.0 | 0.006 | H | -64.2 | -36.4 | NA | NA | NA | |||||||||||||
| ILE | C:42 | C:96 | 0.0 | 0.0 | H | -67.2 | -36.2 | NA | NA | NA | |||||||||||||
| ILE | D:42 | D:96 | 0.0 | 0.0 | H | -63.3 | -37.3 | NA | NA | NA | |||||||||||||
| 7rut | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | ILE | A:42 | E:96 | 0.0 | 0.0 | H | -63.2 | -38.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.218 |
N |
O |
||
| ILE | B:42 | C:96 | 0.0 | 0.0 | H | -65.0 | -38.2 | NA | NA | NA | |||||||||||||
| ILE | C:42 | F:96 | 0.0 | 0.0 | H | -61.7 | -38.2 | NA | NA | NA | |||||||||||||
| ILE | D:42 | B:96 | 0.0 | 0.0 | H | -63.9 | -38.1 | NA | NA | NA | |||||||||||||
| ILE | E:42 | A:96 | 0.0 | 0.0 | H | -64.9 | -37.7 | NA | NA | NA | |||||||||||||
| ILE | F:42 | D:96 | 0.0 | 0.0 | H | -62.9 | -36.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.140 |
N |
O |
|||||||||
| 7ruu | 1 | Q96EY8 | 98.98 | 2e-143 |
X-RAY |
2021-11-24 | ILE | A:42 | A:96 | 0.0 | 0.0 | H | -64.4 | -35.3 | 0.0 | 0.0 | 0.0 |
ACT HOH |
8.801 5.555 |
CD1 C |
CH3 O |
||
| ILE | B:42 | B:96 | 0.0 | 0.0 | H | -64.0 | -38.9 | NA | NA | NA | |||||||||||||
| ILE | C:42 | C:96 | 0.0 | 0.0 | H | -60.9 | -38.9 | NA | NA | NA | |||||||||||||
| ILE | D:42 | D:96 | 0.0 | 0.0 | H | -65.1 | -38.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q96ey8-f1 | 1 | Q96EY8 | 100.0 | 0.0 | ILE | A:96 | A:96 | 1.0 | 0.006 | H | -63.9 | -41.3 | |