Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 117013859 | . | T | A | CCDS41841.1:NM_001085481.1:c.112Tac>Aac_NP_001078950.1:p.38Y>N | Homo sapiens microtubule associated protein 1 light chain 3 beta 2 (MAP1LC3B2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5gmv | 1 | Q9GZQ8 | 99.2 | 1e-88 |
X-RAY |
2017-03-08 | TYR | A:38 | B:38 | 67.0 | 0.291 | -62.9 | 138.2 | 67.0 | 0.291 | 0.0 |
HOH |
2.847 |
O |
O |
|||
TYR | C:38 | A:38 | 62.0 | 0.27 | -50.3 | 143.2 | NA | NA | NA | ||||||||||||||
2zjd | 1 | Q9GZQ8 | 99.2 | 2e-88 |
X-RAY |
2008-06-03 | TYR | A:43 | A:38 | 46.0 | 0.2 | -53.3 | 139.6 | 46.0 | 0.2 | 0.0 |
HOH |
2.912 |
O |
O |
|||
TYR | C:43 | C:38 | 34.0 | 0.148 | -52.8 | 142.0 | NA | NA | NA | ||||||||||||||
5d94 | 1 | Q9GZQ8 | 99.2 | 2e-88 |
X-RAY |
2015-10-21 | TYR | A:43 | A:38 | 74.0 | 0.322 | -55.7 | 133.1 | 74.0 | 0.322 | 0.0 |
HOH |
3.049 |
O |
O |
|||
6lan | 1 | Q8IVM0,Q9GZQ8 | 98.4 | 1e-87 |
X-RAY |
2020-09-30 | TYR | A:48 | A:38 | 45.0 | 0.196 | -54.1 | 138.8 | 45.0 | 0.196 | 0.0 |
HOH |
2.748 |
HA |
O |
|||
5wrd | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2017-03-29 | TYR | A:38 | A:38 | 87.0 | 0.378 | -56.4 | 129.1 | 87.0 | 0.378 | 0.0 |
HOH |
3.096 |
O |
O |
|||
TYR | B:38 | B:38 | 61.0 | 0.265 | -60.0 | 132.0 | NA | NA | NA | ||||||||||||||
5yiq | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2018-05-23 | TYR | A:38 | A:38 | 72.0 | 0.313 | -57.3 | 135.3 | 72.0 | 0.313 | 0.0 |
HOH |
7.829 |
CD1 |
O |
|||
5yis | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2018-05-23 | TYR | A:38 | A:38 | 111.0 | 0.483 | -54.8 | 135.3 | 111.0 | 0.483 | 0.0 |
HOH |
3.558 |
CD1 |
O |
|||
TYR | B:38 | B:38 | 76.0 | 0.33 | -58.5 | 140.0 | NA | NA | NA | ||||||||||||||
2n9x | 1 | Q9GZQ8 | 99.17 | 4e-85 |
NMR |
2016-12-14 | TYR | A:38 | A:38 | 32.0 | 0.139 | -57.0 | 117.8 | 32.0 | 0.139 | 0.0 | |||||||
2z0e | 2 | Q62625 | 95.16 | 8e-85 |
X-RAY |
2007-05-22 | TYR | B:43 | B:38 | 107.0 | 0.465 | -54.4 | 139.1 | 24.0 | 0.104 | 0.361 |
A:Q9Y4P1:0.361 |
HOH |
3.138 |
O |
O |
||
2zzp | 2 | Q62625 | 95.16 | 8e-85 |
X-RAY |
2009-03-03 | TYR | B:43 | B:38 | 104.0 | 0.452 | -54.1 | 136.6 | 19.0 | 0.083 | 0.369 |
A:Q9Y4P1:0.37 |
HOH |
3.300 |
O |
O |
||
6j04 | 1 | Q9GZQ8 | 98.39 | 8e-85 |
X-RAY |
2019-11-06 | TYR | A:38 | A:38 | 71.0 | 0.309 | -55.6 | 136.4 | 69.0 | 0.3 | 0.009 |
C:Q9GZQ8:0.009 |
SO4 HOH |
8.407 3.085 |
O CD1 |
O1 O |
||
TYR | B:38 | B:38 | 80.0 | 0.348 | -55.1 | 133.8 | NA | NA | NA | ||||||||||||||
TYR | C:38 | C:38 | 37.0 | 0.161 | -51.4 | 133.8 | NA | NA | NA | ||||||||||||||
TYR | D:38 | D:38 | 57.0 | 0.248 | -56.9 | 135.9 | NA | NA | NA | ||||||||||||||
5xad | 1 | Q9GZQ8 | 99.16 | 3e-84 |
X-RAY |
2017-07-12 | TYR | A:37 | A:38 | 119.0 | 0.517 | -47.5 | 142.3 | 119.0 | 0.517 | 0.0 |
HOH |
4.698 |
C |
O |
|||
TYR | B:37 | B:38 | 80.0 | 0.348 | -51.9 | 140.3 | NA | NA | NA | ||||||||||||||
2k6q | 1 | Q62625 | 97.5 | 4e-84 |
NMR |
2008-09-02 | TYR | A:39 | A:38 | 71.0 | 0.309 | -58.8 | 139.1 | 71.0 | 0.309 | 0.0 | |||||||
5xac | 1 | Q9GZQ8 | 99.16 | 5e-84 |
X-RAY |
2017-07-12 | TYR | A:48 | A:38 | 103.0 | 0.448 | -52.9 | 134.8 | 103.0 | 0.448 | 0.0 |
HOH |
2.866 |
O |
O |
|||
TYR | B:48 | B:38 | 87.0 | 0.378 | -54.4 | 142.8 | 75.0 | 0.326 | 0.052 |
C:Q9GZQ8:0.052 |
HOH |
2.693 |
OH |
O |
|||||||||
TYR | C:48 | C:38 | 108.0 | 0.47 | -55.4 | 142.0 | 108.0 | 0.47 | 0.0 |
HOH |
3.622 |
CD1 |
O |
||||||||||
TYR | D:48 | D:38 | 77.0 | 0.335 | -48.3 | 133.6 | 77.0 | 0.335 | 0.0 |
HOH |
2.941 |
O |
O |
||||||||||
5xae | 1 | Q9GZQ8 | 99.16 | 6e-84 |
X-RAY |
2017-07-12 | TYR | A:60 | A:36 | 51.0 | 0.222 | -51.4 | 135.5 | 51.0 | 0.222 | 0.0 |
HOH |
2.927 |
O |
O |
|||
TYR | B:60 | B:36 | 76.0 | 0.33 | -49.5 | 130.8 | 76.0 | 0.33 | 0.0 |
HOH |
2.842 |
O |
O |
||||||||||
TYR | C:60 | C:36 | 67.0 | 0.291 | -50.9 | 135.4 | 32.0 | 0.139 | 0.152 |
A:Q9GZQ8:0.074 B:Q9GZQ8:0.078 |
HOH |
2.561 |
O |
O |
|||||||||
TYR | D:60 | D:36 | 72.0 | 0.313 | -48.0 | 130.8 | 72.0 | 0.313 | 0.0 |
HOH |
3.124 |
O |
O |
||||||||||
1ugm | 1 | Q62625 | 97.5 | 7e-84 |
X-RAY |
2004-07-06 | TYR | A:43 | A:38 | 132.0 | 0.574 | -58.4 | 133.6 | 132.0 | 0.574 | 0.0 |
HOH |
5.772 |
N |
O |
|||
2z0d | 2 | Q62625 | 97.5 | 7e-84 |
X-RAY |
2007-05-22 | TYR | B:43 | B:38 | 107.0 | 0.465 | -53.6 | 142.0 | 24.0 | 0.104 | 0.361 |
A:Q9Y4P1:0.361 |
HOH |
2.597 |
OH |
O |
||
5ms2 | 2 | Q9GZQ8 | 99.16 | 2e-83 |
X-RAY |
2017-04-19 | TYR | B:43 | B:38 | 78.0 | 0.339 | -53.6 | 128.8 | 78.0 | 0.339 | 0.0 | |||||||
5v4k | 1 | Q9GZQ8 | 99.15 | 3e-83 |
X-RAY |
2017-05-17 | TYR | A:51 | A:1038 | 104.0 | 0.452 | -52.4 | 144.6 | 104.0 | 0.452 | 0.0 |
HOH |
4.119 |
CE1 |
O |
|||
TYR | B:51 | B:1038 | 113.0 | 0.491 | -51.9 | 142.3 | 113.0 | 0.491 | 0.0 |
HOH |
3.363 |
CD1 |
O |
||||||||||
3vtw | 1 | Q96CV9,Q9GZQ8 | 99.15 | 4e-83 |
X-RAY |
2013-06-26 | TYR | A:68 | A:53 | 63.0 | 0.274 | -56.9 | 129.4 | 63.0 | 0.274 | 0.0 |
HOH |
2.777 |
O |
O |
|||
TYR | B:68 | B:53 | 74.0 | 0.322 | -55.7 | 123.7 | NA | NA | NA | ||||||||||||||
TYR | C:68 | C:53 | 78.0 | 0.339 | -60.5 | 134.2 | NA | NA | NA | ||||||||||||||
3wao | 1 | O75143,Q9GZQ8 | 99.15 | 5e-83 |
X-RAY |
2013-12-25 | TYR | A:53 | A:54 | 77.0 | 0.335 | -48.7 | 142.9 | 77.0 | 0.335 | 0.0 | |||||||
TYR | B:53 | B:54 | 120.0 | 0.522 | -52.6 | 140.0 | NA | NA | NA | ||||||||||||||
TYR | C:53 | C:54 | 126.0 | 0.548 | -50.3 | 129.3 | NA | NA | NA | ||||||||||||||
TYR | D:53 | D:54 | 123.0 | 0.535 | -60.7 | 130.6 | NA | NA | NA | ||||||||||||||
3x0w | 1 | Q9GZQ8 | 99.15 | 6e-83 |
X-RAY |
2015-01-14 | TYR | A:53 | A:65 | 67.0 | 0.291 | -55.9 | 140.3 | 67.0 | 0.291 | 0.0 |
HOH |
5.885 |
N |
O |
|||
TYR | B:53 | B:65 | 51.0 | 0.222 | -44.5 | 157.0 | NA | NA | NA | ||||||||||||||
3vtu | 1 | Q9GZQ8 | 98.32 | 7e-83 |
X-RAY |
2013-06-26 | TYR | A:42 | A:42 | 53.0 | 0.23 | -50.9 | 137.0 | 53.0 | 0.23 | 0.0 |
HOH |
2.829 |
O |
O |
|||
7elg | 1 | Q9GZQ8 | 98.32 | 7e-83 |
X-RAY |
2021-10-13 | TYR | A:42 | A:42 | 57.0 | 0.248 | -50.7 | 137.9 | 57.0 | 0.248 | 0.0 |
HOH |
2.792 |
O |
O |
|||
5dcn | 1 | Q9GZQ8 | 99.15 | 8e-83 |
X-RAY |
2016-03-09 | TYR | A:45 | A:38 | 55.0 | 0.239 | -52.2 | 141.0 | 55.0 | 0.239 | 0.0 |
SO4 HOH |
3.781 2.932 |
CA O |
O3 O |
|||
4waa | 1 | Q9GZQ8 | 99.15 | 8e-83 |
X-RAY |
2015-09-09 | TYR | A:53 | A:54 | 94.0 | 0.409 | -49.8 | 133.0 | 94.0 | 0.409 | 0.0 |
HOH |
3.175 |
CD1 |
O |
|||
TYR | B:53 | B:54 | 77.0 | 0.335 | -45.0 | 145.0 | 77.0 | 0.335 | 0.0 |
HOH |
2.927 |
O |
O |
||||||||||
3vtv | 1 | Q96CV9,Q9GZQ8 | 99.15 | 9e-83 |
X-RAY |
2013-06-26 | TYR | A:53 | A:53 | 48.0 | 0.209 | -50.6 | 134.0 | 48.0 | 0.209 | 0.0 |
HOH |
2.782 |
O |
O |
|||
5ms5 | 1 | Q5ZUV9,Q9GZQ8 | 99.15 | 1e-82 |
X-RAY |
2017-04-19 | TYR | A:56 | A:38 | 75.0 | 0.326 | -52.8 | 135.6 | 75.0 | 0.326 | 0.0 |
HOH |
3.052 |
O |
O |
|||
TYR | B:56 | B:38 | 54.0 | 0.235 | -51.2 | 137.2 | NA | NA | NA | ||||||||||||||
5ms6 | 1 | Q9GZQ8 | 99.15 | 1e-82 |
X-RAY |
2017-04-19 | TYR | A:56 | A:38 | 125.0 | 0.543 | -51.5 | 133.8 | 125.0 | 0.543 | 0.0 |
HOH |
3.762 |
CE2 |
O |
|||
TYR | B:56 | B:38 | 94.0 | 0.409 | -50.8 | 136.8 | NA | NA | NA | ||||||||||||||
2lue | 1 | Q9GZQ8 | 99.13 | 9e-81 |
NMR |
2013-07-17 | TYR | A:38 | A:38 | 50.0 | 0.217 | -59.9 | 144.9 | 50.0 | 0.217 | 0.0 | |||||||
5w9a | 2 | Q9GZQ8 | 99.12 | 9e-80 |
X-RAY |
2018-10-10 | TYR | B:35 | C:38 | 121.0 | 0.526 | -64.0 | 158.0 | 121.0 | 0.526 | 0.0 | |||||||
TYR | C:35 | D:38 | 116.0 | 0.504 | -64.2 | 159.0 | 116.0 | 0.504 | 0.0 | ||||||||||||||
7r9w | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | TYR | A:40 | A:38 | 102.0 | 0.443 | -47.1 | 138.4 | 102.0 | 0.443 | 0.0 |
HOH |
4.110 |
C |
O |
|||
7r9z | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | TYR | A:40 | A:38 | 102.0 | 0.443 | -50.1 | 138.9 | 102.0 | 0.443 | 0.0 |
HOH |
2.803 |
O |
O |
|||
7ra0 | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | TYR | A:40 | A:38 | 120.0 | 0.522 | -53.3 | 136.8 | 120.0 | 0.522 | 0.0 |
HOH |
2.967 |
O |
O |
|||
5cx3 | 1 | Q9H492 | 80.99 | 1e-70 |
X-RAY |
2016-08-03 | TYR | A:38 | A:38 | 60.0 | 0.261 | -52.8 | 150.3 | 60.0 | 0.261 | 0.0 |
HOH |
3.576 |
O |
O |
|||
TYR | B:38 | B:38 | 69.0 | 0.3 | -54.3 | 144.6 | NA | NA | NA | ||||||||||||||
TYR | C:38 | C:38 | 57.0 | 0.248 | -53.4 | 143.4 | 39.0 | 0.17 | 0.078 |
A:Q9H492:0.078 |
HOH |
6.115 |
N |
O |
|||||||||
TYR | D:38 | D:38 | 71.0 | 0.309 | -54.9 | 141.5 | NA | NA | NA | ||||||||||||||
3eci | 1 | Q9H492 | 80.99 | 1e-70 |
X-RAY |
2008-10-14 | TYR | A:39 | A:38 | 91.0 | 0.396 | -50.3 | 138.3 | 91.0 | 0.396 | 0.0 | |||||||
TYR | B:39 | B:38 | 24.0 | NA | -64.9 | 139.7 | NA | NA | NA | ||||||||||||||
3wal | 1 | Q9H492 | 80.17 | 1e-69 |
X-RAY |
2013-12-25 | TYR | A:42 | A:42 | 94.0 | 0.409 | -49.4 | 141.7 | 94.0 | 0.409 | 0.0 |
HOH |
2.622 |
O |
O |
|||
3wan | 1 | O75143,Q9H492 | 80.83 | 1e-69 |
X-RAY |
2013-12-25 | TYR | A:53 | A:54 | 74.0 | 0.322 | -49.4 | 128.9 | 74.0 | 0.322 | 0.0 |
HOH |
3.642 |
CA |
O |
|||
TYR | B:53 | B:54 | 56.0 | 0.243 | -57.0 | 138.0 | 28.0 | 0.122 | 0.121 |
A:O75143+Q9H492:0.122 |
HOH |
2.544 |
OH |
O |
|||||||||
5dpr | 1 | Q9Y4G2,Q9H492 | 80.83 | 2e-69 |
X-RAY |
2016-09-28 | TYR | A:53 | A:49 | 107.0 | 0.465 | -61.5 | 146.6 | 107.0 | 0.465 | 0.0 |
HOH |
6.902 |
HA |
O |
|||
TYR | B:53 | B:49 | 76.0 | 0.33 | -61.2 | 145.9 | NA | NA | NA | ||||||||||||||
TYR | C:53 | C:49 | 86.0 | 0.374 | -61.5 | 147.8 | NA | NA | NA | ||||||||||||||
TYR | D:53 | D:49 | 109.0 | 0.474 | -61.4 | 146.9 | NA | NA | NA | ||||||||||||||
4zdv | 1 | Q9H492 | 81.51 | 2e-69 |
X-RAY |
2015-06-03 | TYR | A:50 | A:38 | 84.0 | 0.365 | -56.2 | 141.6 | 84.0 | 0.365 | 0.0 |
HOH |
2.755 |
O |
O |
|||
6tbe | 1 | Q9H492 | 81.03 | 4e-67 |
X-RAY |
2020-11-18 | TYR | A:38 | A:42 | 108.0 | 0.47 | -50.2 | 138.1 | 108.0 | 0.47 | 0.0 |
HOH |
2.759 |
O |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-a6nce7-f1 | 1 | A6NCE7 | 100.0 | 1e-90 | TYR | A:38 | A:38 | 52.0 | 0.226 | -56.9 | 145.7 | ||
af-q9gzq8-f1 | 1 | Q9GZQ8 | 99.2 | 5e-89 | TYR | A:38 | A:38 | 55.0 | 0.239 | -57.7 | 143.2 | ||
af-q9h492-f1 | 1 | Q9H492 | 80.99 | 5e-71 | TYR | A:38 | A:38 | 72.0 | 0.313 | -56.9 | 145.7 |