Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 117013925 | . | A | C | CCDS41841.1:NM_001085481.1:c.178Atg>Ctg_NP_001078950.1:p.60M>L | Homo sapiens microtubule associated protein 1 light chain 3 beta 2 (MAP1LC3B2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5gmv | 1 | Q9GZQ8 | 99.2 | 1e-88 |
X-RAY |
2017-03-08 | MET | A:60 | B:60 | 6.0 | 0.032 | H | -63.6 | -37.4 | 6.0 | 0.032 | 0.0 |
HOH |
4.923 |
SD |
O |
||
MET | C:60 | A:60 | 5.0 | 0.027 | H | -57.4 | -34.4 | NA | NA | NA | |||||||||||||
2zjd | 1 | Q9GZQ8 | 99.2 | 2e-88 |
X-RAY |
2008-06-03 | MET | A:65 | A:60 | 0.0 | 0.0 | H | -61.3 | -33.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.294 |
O |
O |
||
MET | C:65 | C:60 | 4.0 | 0.022 | H | -61.3 | -37.6 | NA | NA | NA | |||||||||||||
5d94 | 1 | Q9GZQ8 | 99.2 | 2e-88 |
X-RAY |
2015-10-21 | MET | A:65 | A:60 | 2.0 | 0.011 | H | -66.7 | -33.6 | 2.0 | 0.011 | 0.0 |
HOH |
5.204 |
O |
O |
||
6lan | 1 | Q8IVM0,Q9GZQ8 | 98.4 | 1e-87 |
X-RAY |
2020-09-30 | MET | A:70 | A:60 | 3.0 | 0.016 | H | -63.9 | -34.7 | 3.0 | 0.016 | 0.0 |
HOH |
2.878 |
HE3 |
O |
||
5wrd | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2017-03-29 | MET | A:60 | A:60 | 4.0 | 0.022 | H | -57.6 | -36.5 | 4.0 | 0.022 | 0.0 |
GOL HOH |
4.020 6.199 |
CE N |
C3 O |
||
MET | B:60 | B:60 | 3.0 | 0.016 | H | -63.2 | -41.5 | NA | NA | NA | |||||||||||||
5yiq | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2018-05-23 | MET | A:60 | A:60 | 7.0 | 0.038 | H | -67.1 | -36.6 | 7.0 | 0.038 | 0.0 | ||||||
5yis | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2018-05-23 | MET | A:60 | A:60 | 4.0 | 0.022 | H | -58.3 | -43.6 | 4.0 | 0.022 | 0.0 |
GOL |
3.254 |
CE |
O3 |
||
MET | B:60 | B:60 | 4.0 | 0.022 | H | -58.4 | -39.2 | NA | NA | NA | |||||||||||||
2n9x | 1 | Q9GZQ8 | 99.17 | 4e-85 |
NMR |
2016-12-14 | MET | A:60 | A:60 | 0.0 | 0.0 | H | -58.5 | -38.1 | 0.0 | 0.0 | 0.0 | ||||||
2z0e | 2 | Q62625 | 95.16 | 8e-85 |
X-RAY |
2007-05-22 | MET | B:65 | B:60 | 4.0 | 0.022 | H | -55.6 | -36.9 | 4.0 | 0.022 | 0.0 |
HOH |
5.011 |
O |
O |
||
2zzp | 2 | Q62625 | 95.16 | 8e-85 |
X-RAY |
2009-03-03 | MET | B:65 | B:60 | 2.0 | 0.011 | H | -63.7 | -31.3 | 2.0 | 0.011 | 0.0 |
HOH |
4.790 |
O |
O |
||
6j04 | 1 | Q9GZQ8 | 98.39 | 8e-85 |
X-RAY |
2019-11-06 | MET | A:60 | A:60 | 2.0 | 0.011 | H | -62.4 | -29.1 | 2.0 | 0.011 | 0.0 |
HOH |
5.316 |
O |
O |
||
MET | B:60 | B:60 | 3.0 | 0.016 | H | -52.0 | -31.2 | NA | NA | NA | |||||||||||||
MET | C:60 | C:60 | 3.0 | 0.016 | H | -60.5 | -37.9 | NA | NA | NA | |||||||||||||
MET | D:60 | D:60 | 2.0 | 0.011 | H | -61.8 | -35.5 | NA | NA | NA | |||||||||||||
5xad | 1 | Q9GZQ8 | 99.16 | 3e-84 |
X-RAY |
2017-07-12 | MET | A:59 | A:60 | 1.0 | 0.005 | H | -63.6 | -37.9 | 1.0 | 0.005 | 0.0 |
HOH |
2.757 |
N |
O |
||
MET | B:59 | B:60 | 14.0 | 0.076 | H | -60.7 | -36.0 | NA | NA | NA | |||||||||||||
2k6q | 1 | Q62625 | 97.5 | 4e-84 |
NMR |
2008-09-02 | MET | A:61 | A:60 | 5.0 | 0.027 | H | -44.7 | -28.1 | 5.0 | 0.027 | 0.0 | ||||||
5xac | 1 | Q9GZQ8 | 99.16 | 5e-84 |
X-RAY |
2017-07-12 | MET | A:70 | A:60 | 3.0 | 0.016 | H | -64.3 | -35.2 | 3.0 | 0.016 | 0.0 |
HOH |
2.882 |
N |
O |
||
MET | B:70 | B:60 | 5.0 | 0.027 | H | -62.1 | -36.0 | 2.0 | 0.011 | 0.016 |
D:Q9GZQ8:0.016 |
HOH |
2.838 |
N |
O |
||||||||
MET | C:70 | C:60 | 2.0 | 0.011 | H | -57.1 | -34.9 | 2.0 | 0.011 | 0.0 |
HOH |
4.003 |
CE |
O |
|||||||||
MET | D:70 | D:60 | 2.0 | 0.011 | H | -59.9 | -35.2 | 2.0 | 0.011 | 0.0 |
HOH |
3.966 |
CE |
O |
|||||||||
5xae | 1 | Q9GZQ8 | 99.16 | 6e-84 |
X-RAY |
2017-07-12 | MET | A:82 | A:58 | 23.0 | 0.124 | H | -58.4 | -39.1 | 23.0 | 0.124 | 0.0 |
HOH |
5.191 |
O |
O |
||
MET | B:82 | B:58 | 42.0 | 0.227 | H | -59.6 | -40.0 | 42.0 | 0.227 | 0.0 |
HOH |
6.649 |
O |
O |
|||||||||
MET | C:82 | C:58 | 0.0 | 0.0 | H | -60.2 | -36.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.463 |
CG |
O |
|||||||||
MET | D:82 | D:58 | 0.0 | 0.0 | H | -58.9 | -40.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.165 |
O |
O |
|||||||||
1ugm | 1 | Q62625 | 97.5 | 7e-84 |
X-RAY |
2004-07-06 | MET | A:65 | A:60 | 1.0 | 0.005 | H | -59.5 | -31.2 | 1.0 | 0.005 | 0.0 |
HOH |
5.271 |
O |
O |
||
2z0d | 2 | Q62625 | 97.5 | 7e-84 |
X-RAY |
2007-05-22 | MET | B:65 | B:60 | 3.0 | 0.016 | H | -55.8 | -44.8 | 3.0 | 0.016 | 0.0 |
HOH |
3.568 |
CE |
O |
||
5ms2 | 2 | Q9GZQ8 | 99.16 | 2e-83 |
X-RAY |
2017-04-19 | MET | B:65 | B:60 | 2.0 | 0.011 | H | -62.3 | -29.2 | 2.0 | 0.011 | 0.0 |
HOH |
4.685 |
CE |
O |
||
5v4k | 1 | Q9GZQ8 | 99.15 | 3e-83 |
X-RAY |
2017-05-17 | MET | A:73 | A:1060 | 2.0 | 0.011 | H | -67.8 | -37.8 | 2.0 | 0.011 | 0.0 |
GOL HOH |
7.660 2.925 |
CG N |
C3 O |
||
MET | B:73 | B:1060 | 3.0 | 0.016 | H | -65.7 | -34.4 | 3.0 | 0.016 | 0.0 |
GOL HOH |
7.559 2.857 |
CG N |
O2 O |
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3vtw | 1 | Q96CV9,Q9GZQ8 | 99.15 | 4e-83 |
X-RAY |
2013-06-26 | MET | A:90 | A:75 | 0.0 | 0.0 | H | -52.1 | -41.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.361 |
O |
O |
||
MET | B:90 | B:75 | 1.0 | 0.005 | H | -58.6 | -45.4 | NA | NA | NA | |||||||||||||
MET | C:90 | C:75 | 0.0 | 0.0 | H | -50.5 | -50.2 | NA | NA | NA | |||||||||||||
3wao | 1 | O75143,Q9GZQ8 | 99.15 | 5e-83 |
X-RAY |
2013-12-25 | MET | A:75 | A:76 | 1.0 | 0.005 | H | -59.2 | -43.5 | 1.0 | 0.005 | 0.0 | ||||||
MET | B:75 | B:76 | 12.0 | 0.065 | H | -51.3 | -45.4 | NA | NA | NA | |||||||||||||
MET | C:75 | C:76 | 6.0 | 0.032 | H | -42.8 | -50.0 | NA | NA | NA | |||||||||||||
MET | D:75 | D:76 | 7.0 | 0.038 | H | -67.4 | -31.3 | NA | NA | NA | |||||||||||||
3x0w | 1 | Q9GZQ8 | 99.15 | 6e-83 |
X-RAY |
2015-01-14 | MET | A:75 | A:87 | 1.0 | 0.005 | H | -57.9 | -39.2 | 1.0 | 0.005 | 0.0 |
HOH |
6.762 |
SD |
O |
||
MET | B:75 | B:87 | 1.0 | 0.005 | H | -59.2 | -38.5 | NA | NA | NA | |||||||||||||
3vtu | 1 | Q9GZQ8 | 98.32 | 7e-83 |
X-RAY |
2013-06-26 | MET | A:64 | A:64 | 0.0 | 0.0 | H | -72.3 | -28.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.241 |
CB |
O |
||
7elg | 1 | Q9GZQ8 | 98.32 | 7e-83 |
X-RAY |
2021-10-13 | MET | A:64 | A:64 | 0.0 | 0.0 | H | -65.9 | -36.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.578 |
C |
O |
||
5dcn | 1 | Q9GZQ8 | 99.15 | 8e-83 |
X-RAY |
2016-03-09 | MET | A:67 | A:60 | 0.0 | 0.0 | H | -64.1 | -39.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.577 |
O |
O |
||
4waa | 1 | Q9GZQ8 | 99.15 | 8e-83 |
X-RAY |
2015-09-09 | MET | A:75 | A:76 | 3.0 | 0.016 | H | -60.6 | -31.4 | 3.0 | 0.016 | 0.0 |
HOH |
2.869 |
N |
O |
||
MET | B:75 | B:76 | 2.0 | 0.011 | H | -69.0 | -29.2 | 2.0 | 0.011 | 0.0 |
HOH |
2.968 |
N |
O |
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3vtv | 1 | Q96CV9,Q9GZQ8 | 99.15 | 9e-83 |
X-RAY |
2013-06-26 | MET | A:75 | A:75 | 0.0 | 0.0 | H | -63.1 | -36.6 | 0.0 | 0.0 | 0.0 |
HOH |
2.841 |
N |
O |
||
5ms5 | 1 | Q5ZUV9,Q9GZQ8 | 99.15 | 1e-82 |
X-RAY |
2017-04-19 | MET | A:78 | A:60 | 3.0 | 0.016 | H | -67.3 | -35.0 | 3.0 | 0.016 | 0.0 |
HOH |
2.990 |
N |
O |
||
MET | B:78 | B:60 | 4.0 | 0.022 | H | -65.3 | -34.7 | NA | NA | NA | |||||||||||||
5ms6 | 1 | Q9GZQ8 | 99.15 | 1e-82 |
X-RAY |
2017-04-19 | MET | A:78 | A:60 | 2.0 | 0.011 | H | -67.5 | -34.2 | 2.0 | 0.011 | 0.0 |
HOH |
3.249 |
N |
O |
||
MET | B:78 | B:60 | 2.0 | 0.011 | H | -65.7 | -34.5 | NA | NA | NA | |||||||||||||
2lue | 1 | Q9GZQ8 | 99.13 | 9e-81 |
NMR |
2013-07-17 | MET | A:60 | A:60 | 10.0 | 0.054 | H | -63.1 | -32.2 | 10.0 | 0.054 | 0.0 | ||||||
5w9a | 2 | Q9GZQ8 | 99.12 | 9e-80 |
X-RAY |
2018-10-10 | MET | B:57 | C:60 | 5.0 | 0.027 | H | -65.9 | -23.6 | 5.0 | 0.027 | 0.0 | ||||||
MET | C:57 | D:60 | 5.0 | 0.027 | H | -66.4 | -23.3 | 5.0 | 0.027 | 0.0 | |||||||||||||
7r9w | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | MET | A:62 | A:60 | 0.0 | 0.0 | H | -60.0 | -32.6 | 0.0 | 0.0 | 0.0 |
JO4 HOH |
9.309 5.336 |
O O |
C06 O |
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7r9z | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | MET | A:62 | A:60 | 0.0 | 0.0 | H | -58.6 | -37.4 | 0.0 | 0.0 | 0.0 |
2LZ HOH |
8.738 5.523 |
O O |
N10 O |
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7ra0 | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | MET | A:62 | A:60 | 1.0 | 0.005 | H | -57.9 | -38.6 | 1.0 | 0.005 | 0.0 |
2JI 2JI HOH |
9.135 6.432 5.481 |
O CG O |
C4 C5 O |
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5cx3 | 1 | Q9H492 | 80.99 | 1e-70 |
X-RAY |
2016-08-03 | MET | A:60 | A:60 | 3.0 | 0.016 | H | -53.0 | -38.1 | 3.0 | 0.016 | 0.0 |
HOH |
4.080 |
CG |
O |
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MET | B:60 | B:60 | 4.0 | 0.022 | H | -53.4 | -40.4 | NA | NA | NA | |||||||||||||
MET | C:60 | C:60 | 1.0 | 0.005 | H | -58.5 | -38.2 | 1.0 | 0.005 | 0.0 |
HOH |
5.434 |
CG |
O |
|||||||||
MET | D:60 | D:60 | 2.0 | 0.011 | H | -57.6 | -38.4 | NA | NA | NA | |||||||||||||
3eci | 1 | Q9H492 | 80.99 | 1e-70 |
X-RAY |
2008-10-14 | MET | A:61 | A:60 | 4.0 | 0.022 | H | -53.3 | -34.1 | 4.0 | 0.022 | 0.0 | ||||||
MET | B:61 | B:60 | 8.0 | 0.043 | H | -59.1 | -24.8 | NA | NA | NA | |||||||||||||
3wal | 1 | Q9H492 | 80.17 | 1e-69 |
X-RAY |
2013-12-25 | MET | A:64 | A:64 | 0.0 | 0.0 | H | -59.1 | -36.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.458 |
O |
O |
||
3wan | 1 | O75143,Q9H492 | 80.83 | 1e-69 |
X-RAY |
2013-12-25 | MET | A:75 | A:76 | 6.0 | 0.032 | H | -66.2 | -33.8 | 1.0 | 0.005 | 0.027 |
B:O75143+Q9H492:0.027 |
HOH |
2.836 |
N |
O |
|
MET | B:75 | B:76 | 7.0 | 0.038 | H | -56.5 | -40.5 | 7.0 | 0.038 | 0.0 |
HOH |
2.789 |
N |
O |
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5dpr | 1 | Q9Y4G2,Q9H492 | 80.83 | 2e-69 |
X-RAY |
2016-09-28 | MET | A:75 | A:71 | 1.0 | 0.005 | H | -66.2 | -30.1 | 1.0 | 0.005 | 0.0 |
HOH |
6.170 |
HG3 |
O |
||
MET | B:75 | B:71 | 0.0 | 0.0 | H | -64.6 | -30.9 | NA | NA | NA | |||||||||||||
MET | C:75 | C:71 | 14.0 | 0.076 | H | -63.7 | -32.7 | NA | NA | NA | |||||||||||||
MET | D:75 | D:71 | 4.0 | 0.022 | H | -64.5 | -31.4 | NA | NA | NA | |||||||||||||
4zdv | 1 | Q9H492 | 81.51 | 2e-69 |
X-RAY |
2015-06-03 | MET | A:72 | A:60 | 1.0 | 0.005 | H | -63.0 | -41.0 | 1.0 | 0.005 | 0.0 |
HOH |
5.376 |
O |
O |
||
6tbe | 1 | Q9H492 | 81.03 | 4e-67 |
X-RAY |
2020-11-18 | MET | A:60 | A:64 | 0.0 | 0.0 | H | -55.1 | -42.2 | 0.0 | 0.0 | 0.0 |
NOV HOH |
8.955 5.404 |
CE O |
C25 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-a6nce7-f1 | 1 | A6NCE7 | 100.0 | 1e-90 | MET | A:60 | A:60 | 3.0 | 0.016 | H | -59.6 | -33.6 | |
af-q9gzq8-f1 | 1 | Q9GZQ8 | 99.2 | 5e-89 | MET | A:60 | A:60 | 4.0 | 0.022 | H | -58.2 | -33.9 | |
af-q9h492-f1 | 1 | Q9H492 | 80.99 | 5e-71 | MET | A:60 | A:60 | 7.0 | 0.038 | H | -58.5 | -36.0 |