Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 117014081 . G A CCDS41841.1:NM_001085481.1:c.334Gtc>Atc_NP_001078950.1:p.112V>I Homo sapiens microtubule associated protein 1 light chain 3 beta 2 (MAP1LC3B2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5gmv 1 Q9GZQ8 99.2 1e-88 X-RAY
 2017-03-08 VAL A:112 B:112 27.0 0.174 E -121.7 146.3 27.0 0.174 0.0 HOH
 3.650
 N
 O
VAL C:112 A:112 24.0 0.155 E -124.2 149.5 NA NA NA
2zjd 1 Q9GZQ8 99.2 2e-88 X-RAY
 2008-06-03 VAL A:117 A:112 23.0 0.148 E -125.8 153.0 23.0 0.148 0.0 HOH
 3.603
 CG1
 O
VAL C:117 C:112 33.0 0.213 E -122.9 151.7 NA NA NA
5d94 1 Q9GZQ8 99.2 2e-88 X-RAY
 2015-10-21 VAL A:117 A:112 35.0 0.226 E -145.9 134.1 35.0 0.226 0.0 HOH
 3.937
 CG2
 O
6lan 1 Q8IVM0,Q9GZQ8 98.4 1e-87 X-RAY
 2020-09-30 VAL A:122 A:112 35.0 0.226 E -125.6 149.1 35.0 0.226 0.0 HOH
 2.937
 HG13
 O
5wrd 1 Q9CQV6 94.4 2e-85 X-RAY
 2017-03-29 VAL A:112 A:112 24.0 0.155 E -120.3 138.3 24.0 0.155 0.0 GOL
HOH
 7.067
4.033
 O
CG2
 O1
O
VAL B:112 B:112 21.0 0.135 E -126.3 149.8 NA NA NA
5yiq 1 Q9CQV6 94.4 2e-85 X-RAY
 2018-05-23 VAL A:112 A:112 38.0 0.245 E -133.4 148.0 38.0 0.245 0.0 HOH
 3.641
 CG2
 O
5yis 1 Q9CQV6 94.4 2e-85 X-RAY
 2018-05-23 VAL A:112 A:112 32.0 0.206 E -127.2 136.0 32.0 0.206 0.0 GOL
HOH
 6.806
4.020
 O
CG2
 O1
O
VAL B:112 B:112 22.0 0.142 E -127.8 146.8 NA NA NA
2n9x 1 Q9GZQ8 99.17 4e-85 NMR
 2016-12-14 VAL A:112 A:112 46.0 0.297 E -85.4 145.1 46.0 0.297 0.0
2z0e 2 Q62625 95.16 8e-85 X-RAY
 2007-05-22 VAL B:117 B:112 44.0 0.284 E -129.0 146.2 33.0 0.213 0.071 A:Q9Y4P1:0.071
 HOH
 3.473
 CG2
 O
2zzp 2 Q62625 95.16 8e-85 X-RAY
 2009-03-03 VAL B:117 B:112 48.0 0.31 E -133.6 151.8 37.0 0.239 0.071 A:Q9Y4P1:0.071
 HOH
 3.498
 CG1
 O
6j04 1 Q9GZQ8 98.39 8e-85 X-RAY
 2019-11-06 VAL A:112 A:112 11.0 0.071 E -126.7 148.1 11.0 0.071 0.0 HOH
 3.182
 CG1
 O
VAL B:112 B:112 21.0 0.135 E -126.2 152.4 NA NA NA
VAL C:112 C:112 18.0 0.116 E -129.8 144.1 NA NA NA
VAL D:112 D:112 23.0 0.148 E -131.8 137.9 NA NA NA
5xad 1 Q9GZQ8 99.16 3e-84 X-RAY
 2017-07-12 VAL A:111 A:112 42.0 0.271 E -131.3 142.2 42.0 0.271 0.0 HOH
 3.151
 CG2
 O
VAL B:111 B:112 38.0 0.245 E -128.5 148.6 NA NA NA
2k6q 1 Q62625 97.5 4e-84 NMR
 2008-09-02 VAL A:113 A:112 39.0 0.252 E -115.5 123.2 39.0 0.252 0.0
5xac 1 Q9GZQ8 99.16 5e-84 X-RAY
 2017-07-12 VAL A:122 A:112 38.0 0.245 E -129.1 136.0 38.0 0.245 0.0 HOH
 3.514
 N
 O
VAL B:122 B:112 51.0 0.329 E -135.6 140.9 51.0 0.329 0.0 HOH
 3.509
 CG2
 O
VAL C:122 C:112 22.0 0.142 E -125.2 147.2 22.0 0.142 0.0 HOH
 3.695
 CG1
 O
VAL D:122 D:112 11.0 0.071 E -138.0 140.4 11.0 0.071 0.0 HOH
 4.573
 CG2
 O
5xae 1 Q9GZQ8 99.16 6e-84 X-RAY
 2017-07-12 VAL A:134 A:110 51.0 0.329 E -131.7 133.5 51.0 0.329 0.0 HOH
 3.311
 CG2
 O
VAL B:134 B:110 51.0 0.329 E -130.2 133.8 51.0 0.329 0.0 HOH
 3.395
 CG2
 O
VAL C:134 C:110 40.0 0.258 E -128.5 133.8 2.0 0.013 0.245 A:Q9GZQ8:0.245
 HOH
 3.633
 CG2
 O
VAL D:134 D:110 52.0 0.335 E -129.9 135.6 52.0 0.335 0.0 HOH
 3.599
 CG2
 O
1ugm 1 Q62625 97.5 7e-84 X-RAY
 2004-07-06 VAL A:117 A:112 45.0 0.29 E -133.5 139.6 45.0 0.29 0.0 HOH
 3.409
 CG2
 O
2z0d 2 Q62625 97.5 7e-84 X-RAY
 2007-05-22 VAL B:117 B:112 45.0 0.29 E -130.2 149.4 34.0 0.219 0.071 A:Q9Y4P1:0.071
 HOH
 3.341
 CG2
 O
5ms2 2 Q9GZQ8 99.16 2e-83 X-RAY
 2017-04-19 VAL B:117 B:112 36.0 0.232 E -130.9 147.5 36.0 0.232 0.0 HOH
 8.213
 O
 O
5v4k 1 Q9GZQ8 99.15 3e-83 X-RAY
 2017-05-17 VAL A:125 A:1112 44.0 0.284 E -132.9 134.3 44.0 0.284 0.0 HOH
 3.353
 CG2
 O
VAL B:125 B:1112 43.0 0.277 E -129.7 134.7 43.0 0.277 0.0 HOH
 3.568
 N
 O
3vtw 1 Q96CV9,Q9GZQ8 99.15 4e-83 X-RAY
 2013-06-26 VAL A:142 A:127 51.0 0.329 E -129.1 137.7 51.0 0.329 0.0 HOH
 3.682
 CG2
 O
VAL B:142 B:127 50.0 0.323 E -126.5 147.4 NA NA NA
VAL C:142 C:127 46.0 0.297 E -126.6 146.5 NA NA NA
3wao 1 O75143,Q9GZQ8 99.15 5e-83 X-RAY
 2013-12-25 VAL A:127 A:128 52.0 0.335 E -125.2 147.0 52.0 0.335 0.0
VAL B:127 B:128 38.0 0.245 E -145.7 139.1 NA NA NA
VAL C:127 C:128 37.0 0.239 E -144.0 144.7 NA NA NA
VAL D:127 D:128 52.0 0.335 E -125.0 138.9 NA NA NA
3x0w 1 Q9GZQ8 99.15 6e-83 X-RAY
 2015-01-14 VAL A:127 A:139 43.0 0.277 E -146.8 141.2 43.0 0.277 0.0 HOH
 7.398
 O
 O
VAL B:127 B:139 48.0 0.31 E -148.4 138.5 NA NA NA
3vtu 1 Q9GZQ8 98.32 7e-83 X-RAY
 2013-06-26 VAL A:116 A:116 46.0 0.297 E -129.1 133.8 46.0 0.297 0.0 HOH
 3.557
 CG2
 O
7elg 1 Q9GZQ8 98.32 7e-83 X-RAY
 2021-10-13 VAL A:116 A:116 48.0 0.31 E -124.3 135.3 48.0 0.31 0.0 HOH
 3.522
 CG2
 O
5dcn 1 Q9GZQ8 99.15 8e-83 X-RAY
 2016-03-09 VAL A:119 A:112 40.0 0.258 E -133.7 133.2 40.0 0.258 0.0 SO4
HOH
 4.009
3.349
 CG1
CG2
 O3
O
4waa 1 Q9GZQ8 99.15 8e-83 X-RAY
 2015-09-09 VAL A:127 A:128 43.0 0.277 E -142.4 129.4 43.0 0.277 0.0 HOH
 3.818
 CG2
 O
VAL B:127 B:128 50.0 0.323 E -134.3 131.0 50.0 0.323 0.0 HOH
 3.113
 CG2
 O
3vtv 1 Q96CV9,Q9GZQ8 99.15 9e-83 X-RAY
 2013-06-26 VAL A:127 A:127 45.0 0.29 E -129.1 138.2 45.0 0.29 0.0 HOH
 3.499
 CG2
 O
5ms5 1 Q5ZUV9,Q9GZQ8 99.15 1e-82 X-RAY
 2017-04-19 VAL A:130 A:112 44.0 0.284 E -134.1 136.5 44.0 0.284 0.0 HOH
 3.531
 CG2
 O
VAL B:130 B:112 39.0 0.252 E -136.6 138.6 NA NA NA
5ms6 1 Q9GZQ8 99.15 1e-82 X-RAY
 2017-04-19 VAL A:130 A:112 47.0 0.303 E -130.3 135.6 47.0 0.303 0.0 HOH
 3.582
 CG2
 O
VAL B:130 B:112 40.0 0.258 E -132.7 136.6 NA NA NA
2lue 1 Q9GZQ8 99.13 9e-81 NMR
 2013-07-17 VAL A:112 A:112 32.0 0.206 E -133.2 146.1 32.0 0.206 0.0
5w9a 2 Q9GZQ8 99.12 9e-80 X-RAY
 2018-10-10 VAL B:109 C:112 36.0 0.232 E -140.5 142.8 36.0 0.232 0.0
VAL C:109 D:112 30.0 0.194 E -140.2 142.9 30.0 0.194 0.0
7r9w 1 Q9H492 81.67 1e-70 X-RAY
 2022-01-12 VAL A:114 A:112 51.0 0.329 E -130.9 139.0 51.0 0.329 0.0 HOH
 3.569
 CG2
 O
7r9z 1 Q9H492 81.67 1e-70 X-RAY
 2022-01-12 VAL A:114 A:112 49.0 0.316 E -132.5 138.9 49.0 0.316 0.0 HOH
 3.817
 CG2
 O
7ra0 1 Q9H492 81.67 1e-70 X-RAY
 2022-01-12 VAL A:114 A:112 54.0 0.348 E -130.2 136.7 54.0 0.348 0.0 HOH
 3.771
 CG2
 O
5cx3 1 Q9H492 80.99 1e-70 X-RAY
 2016-08-03 VAL A:112 A:112 15.0 0.097 E -128.9 150.6 15.0 0.097 0.0 HOH
 3.496
 CG1
 O
VAL B:112 B:112 20.0 0.129 E -126.9 148.5 NA NA NA
VAL C:112 C:112 1.0 0.006 E -128.9 146.3 1.0 0.006 0.0 HOH
 6.546
 CG2
 O
VAL D:112 D:112 19.0 0.123 E -127.2 145.3 NA NA NA
3eci 1 Q9H492 80.99 1e-70 X-RAY
 2008-10-14 VAL A:113 A:112 25.0 0.161 E -139.0 145.5 25.0 0.161 0.0
VAL B:113 B:112 37.0 0.239 E -128.0 154.0 NA NA NA
3wal 1 Q9H492 80.17 1e-69 X-RAY
 2013-12-25 VAL A:116 A:116 50.0 0.323 E -132.2 138.1 50.0 0.323 0.0 HOH
 3.501
 CG2
 O
3wan 1 O75143,Q9H492 80.83 1e-69 X-RAY
 2013-12-25 VAL A:127 A:128 36.0 0.232 E -126.1 138.3 36.0 0.232 0.0 HOH
 3.064
 CG1
 O
VAL B:127 B:128 36.0 0.232 E -131.1 156.9 36.0 0.232 0.0 HOH
 3.466
 CG1
 O
5dpr 1 Q9Y4G2,Q9H492 80.83 2e-69 X-RAY
 2016-09-28 VAL A:127 A:123 47.0 0.303 E -129.0 141.7 47.0 0.303 0.0 HOH
 3.053
 HG23
 O
VAL B:127 B:123 26.0 0.168 E -129.7 142.0 NA NA NA
VAL C:127 C:123 26.0 0.168 E -129.9 141.6 NA NA NA
VAL D:127 D:123 46.0 0.297 E -129.1 142.8 NA NA NA
4zdv 1 Q9H492 81.51 2e-69 X-RAY
 2015-06-03 VAL A:124 A:112 43.0 0.277 E -132.8 140.0 43.0 0.277 0.0 HOH
 3.461
 CG2
 O
6tbe 1 Q9H492 81.03 4e-67 X-RAY
 2020-11-18 VAL A:112 A:116 52.0 0.335 E -130.6 134.3 52.0 0.335 0.0 HOH
 3.556
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-a6nce7-f1 1 A6NCE7 100.0 1e-90 VAL A:112 A:112 27.0 0.174 E -134.1 138.7
af-q9gzq8-f1 1 Q9GZQ8 99.2 5e-89 VAL A:112 A:112 31.0 0.2 E -128.9 141.9
af-q9h492-f1 1 Q9H492 80.99 5e-71 VAL A:112 A:112 19.0 0.123 E -129.8 145.1