Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 117014097 . A C CCDS41841.1:NM_001085481.1:c.350gAg>gCg_NP_001078950.1:p.117E>A Homo sapiens microtubule associated protein 1 light chain 3 beta 2 (MAP1LC3B2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5gmv 1 Q9GZQ8 99.2 1e-88 X-RAY
 2017-03-08 GLU A:117 B:117 112.0 0.589 H -69.2 -35.7 112.0 0.589 0.0 HOH
 2.739
 OE1
 O
GLU C:117 A:117 116.0 0.611 H -65.7 -48.0 NA NA NA
2zjd 1 Q9GZQ8 99.2 2e-88 X-RAY
 2008-06-03 GLU A:122 A:117 105.0 0.553 H -61.3 -57.1 105.0 0.553 0.0 HOH
 2.783
 OE2
 O
GLU C:122 C:117 127.0 0.668 T -104.0 -19.3 NA NA NA
5d94 1 Q9GZQ8 99.2 2e-88 X-RAY
 2015-10-21 GLU A:122 A:117 148.0 0.779 H -66.0 -35.4 148.0 0.779 0.0 HOH
 2.724
 O
 O
6lan 1 Q8IVM0,Q9GZQ8 98.4 1e-87 X-RAY
 2020-09-30 GLU A:127 A:117 119.0 0.626 H -66.6 -43.1 119.0 0.626 0.0 HOH
 2.623
 OE1
 O
5wrd 1 Q9CQV6 94.4 2e-85 X-RAY
 2017-03-29 GLU A:117 A:117 98.0 0.516 S -101.0 -26.1 98.0 0.516 0.0 GOL
HOH
 6.465
5.267
 OE2
O
 C1
O
GLU B:117 B:117 120.0 0.632 T -58.9 -34.9 NA NA NA
5yiq 1 Q9CQV6 94.4 2e-85 X-RAY
 2018-05-23 GLU A:117 A:117 61.0 NA S -70.7 -20.4 61.0 NA NA
5yis 1 Q9CQV6 94.4 2e-85 X-RAY
 2018-05-23 GLU A:117 A:117 99.0 NA -83.0 360.0 99.0 NA NA GOL
HOH
 7.128
3.412
 CA
O
 O1
O
GLU B:117 B:117 154.0 0.811 H -65.8 -38.1 NA NA NA
2n9x 1 Q9GZQ8 99.17 4e-85 NMR
 2016-12-14 GLU A:117 A:117 79.0 0.416 S -61.5 -37.8 79.0 0.416 0.0
2z0e 2 Q62625 95.16 8e-85 X-RAY
 2007-05-22 GLU B:122 B:117 147.0 0.774 -65.5 151.2 51.0 0.268 0.506 A:Q9Y4P1:0.505
 HOH
 2.750
 OE1
 O
2zzp 2 Q62625 95.16 8e-85 X-RAY
 2009-03-03 GLU B:122 B:117 142.0 0.747 -75.3 161.5 62.0 0.326 0.421 A:Q9Y4P1:0.421
 HOH
 2.464
 OE1
 O
6j04 1 Q9GZQ8 98.39 8e-85 X-RAY
 2019-11-06 GLU A:117 A:117 37.0 0.195 H -65.4 -31.2 37.0 0.195 0.0 HOH
 5.341
 CG
 O
GLU B:117 B:117 82.0 0.432 H -67.8 -29.5 NA NA NA
GLU C:117 C:117 89.0 0.468 H -59.7 -46.3 NA NA NA
GLU D:117 D:117 99.0 0.521 H -60.4 -51.3 NA NA NA
5xad 1 Q9GZQ8 99.16 3e-84 X-RAY
 2017-07-12 GLU A:116 A:117 83.0 0.437 -91.1 -21.8 83.0 0.437 0.0 HOH
 2.574
 O
 O
GLU B:116 B:117 108.0 0.568 G -87.3 -17.9 NA NA NA
2k6q 1 Q62625 97.5 4e-84 NMR
 2008-09-02 GLU A:118 A:117 34.0 0.179 S -106.0 -6.4 34.0 0.179 0.0
5xac 1 Q9GZQ8 99.16 5e-84 X-RAY
 2017-07-12 GLU A:127 A:117 101.0 0.532 -78.3 -25.9 101.0 0.532 0.0 HOH
 3.073
 O
 O
GLU B:127 B:117 112.0 0.589 -75.1 -10.8 7.0 0.037 0.552 D:Q9GZQ8:0.553
 HOH
 2.598
 OE2
 O
GLU C:127 NA:NA DO NA DO DO DO NA NA NA
GLU D:127 D:117 134.0 0.705 T -61.4 -24.9 134.0 0.705 0.0 HOH
 2.647
 OE2
 O
5xae 1 Q9GZQ8 99.16 6e-84 X-RAY
 2017-07-12 GLU A:139 A:115 111.0 0.584 S -74.8 -48.6 111.0 0.584 0.0 HOH
 2.064
 OE1
 O
GLU B:139 B:115 117.0 0.616 S -86.4 26.2 117.0 0.616 0.0 HOH
 6.512
 CG
 O
GLU C:139 C:115 89.0 0.468 S -94.8 -22.3 89.0 0.468 0.0 HOH
 2.429
 N
 O
GLU D:139 D:115 78.0 0.411 S -91.6 -21.0 78.0 0.411 0.0 HOH
 3.010
 OE1
 O
1ugm 1 Q62625 97.5 7e-84 X-RAY
 2004-07-06 GLU A:122 A:117 162.0 0.853 -89.7 360.0 162.0 0.853 0.0 HOH
 4.663
 OE1
 O
2z0d 2 Q62625 97.5 7e-84 X-RAY
 2007-05-22 GLU B:122 B:117 149.0 0.784 -65.1 148.9 57.0 0.3 0.484 A:Q9Y4P1:0.484
 HOH
 2.771
 OE2
 O
5ms2 2 Q9GZQ8 99.16 2e-83 X-RAY
 2017-04-19 GLU B:122 B:117 159.0 0.837 -94.5 9.9 159.0 0.837 0.0 HOH
 5.206
 OE2
 O
5v4k 1 Q9GZQ8 99.15 3e-83 X-RAY
 2017-05-17 GLU A:130 A:1117 107.0 0.563 -80.4 20.2 77.0 0.405 0.158 B:Q9GZQ8:0.158
 GOL
HOH
 8.296
2.868
 OE2
OE1
 O1
O
GLU B:130 B:1117 159.0 0.837 -95.4 360.0 135.0 0.711 0.126 A:Q9GZQ8:0.126
 GOL
HOH
 9.670
2.379
 OE2
OE1
 O2
O
3vtw 1 Q96CV9,Q9GZQ8 99.15 4e-83 X-RAY
 2013-06-26 GLU A:147 A:132 72.0 0.379 S -101.9 -23.9 72.0 0.379 0.0 HOH
 2.589
 N
 O
GLU B:147 B:132 111.0 0.584 S -105.6 -2.0 NA NA NA
GLU C:147 C:132 92.0 0.484 S -60.4 -52.9 NA NA NA
3wao 1 O75143,Q9GZQ8 99.15 5e-83 X-RAY
 2013-12-25 GLU A:132 A:133 108.0 0.568 S -123.3 4.9 108.0 0.568 0.0
GLU B:132 B:133 168.0 0.884 -83.5 360.0 NA NA NA
GLU C:132 C:133 143.0 0.753 -140.9 360.0 NA NA NA
GLU D:132 D:133 99.0 0.521 -126.4 25.7 NA NA NA
3x0w 1 Q9GZQ8 99.15 6e-83 X-RAY
 2015-01-14 GLU A:132 A:144 100.0 0.526 -93.0 30.1 100.0 0.526 0.0 HOH
 5.779
 OE2
 O
GLU B:132 B:144 99.0 0.521 -91.9 22.0 NA NA NA
3vtu 1 Q9GZQ8 98.32 7e-83 X-RAY
 2013-06-26 GLU A:121 A:121 115.0 0.605 S -79.6 -30.3 115.0 0.605 0.0 HOH
 2.605
 OE2
 O
7elg 1 Q9GZQ8 98.32 7e-83 X-RAY
 2021-10-13 GLU A:121 A:121 87.0 0.458 S -90.7 -24.4 87.0 0.458 0.0 HOH
 2.820
 OE1
 O
5dcn 1 Q9GZQ8 99.15 8e-83 X-RAY
 2016-03-09 GLU A:124 A:117 147.0 0.774 S -84.5 -0.1 147.0 0.774 0.0 HOH
 3.555
 N
 O
4waa 1 Q9GZQ8 99.15 8e-83 X-RAY
 2015-09-09 GLU A:132 A:133 102.0 0.537 -81.6 -19.2 102.0 0.537 0.0 HOH
 5.826
 OE2
 O
GLU B:132 B:133 105.0 0.553 -86.8 -3.4 105.0 0.553 0.0 HOH
 5.900
 OE2
 O
3vtv 1 Q96CV9,Q9GZQ8 99.15 9e-83 X-RAY
 2013-06-26 GLU A:132 A:132 108.0 0.568 S -86.4 -28.3 108.0 0.568 0.0 HOH
 2.405
 OE1
 O
5ms5 1 Q5ZUV9,Q9GZQ8 99.15 1e-82 X-RAY
 2017-04-19 GLU A:135 A:117 133.0 0.7 57.4 360.0 133.0 0.7 0.0 HOH
 5.467
 O
 O
GLU B:135 B:117 114.0 0.6 60.8 66.7 NA NA NA
5ms6 1 Q9GZQ8 99.15 1e-82 X-RAY
 2017-04-19 GLU A:135 A:117 134.0 0.705 -157.7 360.0 134.0 0.705 0.0 HOH
 2.210
 OE2
 O
GLU B:135 B:117 123.0 0.647 41.6 360.0 NA NA NA
2lue 1 Q9GZQ8 99.13 9e-81 NMR
 2013-07-17 GLU A:117 A:117 146.0 0.768 S -92.3 -15.7 146.0 0.768 0.0
5w9a 2 Q9GZQ8 99.12 9e-80 X-RAY
 2018-10-10 GLU B:114 C:117 148.0 NA 53.6 360.0 148.0 NA NA
GLU C:114 NA:NA DO NA DO DO DO NA NA NA
7r9w 1 Q9H492 81.67 1e-70 X-RAY
 2022-01-12 GLU A:119 A:117 109.0 0.574 -100.7 7.7 109.0 0.574 0.0 HOH
 2.353
 OE2
 O
7r9z 1 Q9H492 81.67 1e-70 X-RAY
 2022-01-12 GLU A:119 A:117 109.0 0.574 -103.2 0.8 109.0 0.574 0.0 HOH
 5.023
 OE2
 O
7ra0 1 Q9H492 81.67 1e-70 X-RAY
 2022-01-12 GLU A:119 A:117 106.0 0.558 -107.8 16.7 106.0 0.558 0.0 2JI
HOH
 7.971
2.800
 OE2
OE2
 O16
O
5cx3 1 Q9H492 80.99 1e-70 X-RAY
 2016-08-03 GLU A:117 A:117 110.0 0.579 G -65.9 -32.5 110.0 0.579 0.0 HOH
 6.930
 O
 O
GLU B:117 B:117 115.0 0.605 G -64.5 -31.6 NA NA NA
GLU C:117 C:117 111.0 0.584 G -62.9 -28.9 108.0 0.568 0.016 A:Q9H492:0.016
 HOH
 3.331
 O
 O
GLU D:117 D:117 116.0 0.611 G -62.5 -26.3 NA NA NA
3eci 1 Q9H492 80.99 1e-70 X-RAY
 2008-10-14 GLU A:118 NA:NA DO NA DO DO DO NA NA NA
GLU B:118 NA:NA DO NA DO DO DO NA NA NA
3wal 1 Q9H492 80.17 1e-69 X-RAY
 2013-12-25 GLU A:121 A:121 110.0 0.579 -97.9 144.4 110.0 0.579 0.0 HOH
 2.860
 OE2
 O
3wan 1 O75143,Q9H492 80.83 1e-69 X-RAY
 2013-12-25 GLU A:132 A:133 94.0 0.495 -75.3 139.0 2.0 0.011 0.484 B:O75143+Q9H492:0.484
 HOH
 5.869
 OE2
 O
GLU B:132 B:133 95.0 0.5 -53.2 -35.0 26.0 0.137 0.363 A:O75143+Q9H492:0.363
 HOH
 2.896
 O
 O
5dpr 1 Q9Y4G2,Q9H492 80.83 2e-69 X-RAY
 2016-09-28 GLU A:132 A:128 90.0 0.474 -78.5 -30.6 90.0 0.474 0.0 HOH
 5.866
 HG3
 O
GLU B:132 B:128 173.0 0.911 T -78.3 -31.3 NA NA NA
GLU C:132 C:128 161.0 0.847 T -78.5 -31.9 NA NA NA
GLU D:132 D:128 113.0 0.595 -80.5 -27.5 NA NA NA
4zdv 1 Q9H492 81.51 2e-69 X-RAY
 2015-06-03 GLU A:129 A:117 81.0 0.426 S -80.3 -54.9 81.0 0.426 0.0 HOH
 2.623
 O
 O
6tbe 1 Q9H492 81.03 4e-67 X-RAY
 2020-11-18 GLU A:117 A:121 99.0 0.521 -98.0 -36.3 99.0 0.521 0.0 HOH
 2.879
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-a6nce7-f1 1 A6NCE7 100.0 1e-90 GLU A:117 A:117 96.0 0.505 H -64.5 -47.4
af-q9gzq8-f1 1 Q9GZQ8 99.2 5e-89 GLU A:117 A:117 99.0 0.521 H -63.8 -45.9
af-q9h492-f1 1 Q9H492 80.99 5e-71 GLU A:117 A:117 141.0 0.742 H -66.8 -29.3