Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 117014099 | . | A | C | CCDS41841.1:NM_001085481.1:c.352Acg>Ccg_NP_001078950.1:p.118T>P | Homo sapiens microtubule associated protein 1 light chain 3 beta 2 (MAP1LC3B2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmv | 1 | Q9GZQ8 | 99.2 | 1e-88 |
X-RAY |
2017-03-08 | THR | A:118 | B:118 | 11.0 | 0.079 | H | -67.2 | -42.6 | 11.0 | 0.079 | 0.0 |
HOH |
2.743 |
OG1 |
O |
||
| THR | C:118 | A:118 | 12.0 | 0.086 | H | -55.5 | -56.3 | NA | NA | NA | |||||||||||||
| 2zjd | 1 | Q9GZQ8 | 99.2 | 2e-88 |
X-RAY |
2008-06-03 | THR | A:123 | A:118 | 8.0 | 0.057 | H | -54.1 | -44.8 | 8.0 | 0.057 | 0.0 |
HOH |
3.273 |
OG1 |
O |
||
| THR | C:123 | C:118 | 16.0 | 0.114 | T | -57.4 | -46.7 | NA | NA | NA | |||||||||||||
| 5d94 | 1 | Q9GZQ8 | 99.2 | 2e-88 |
X-RAY |
2015-10-21 | THR | A:123 | A:118 | 30.0 | 0.214 | H | -73.4 | -40.1 | 30.0 | 0.214 | 0.0 |
HOH |
3.118 |
OG1 |
O |
||
| 6lan | 1 | Q8IVM0,Q9GZQ8 | 98.4 | 1e-87 |
X-RAY |
2020-09-30 | THR | A:128 | A:118 | 13.0 | 0.093 | H | -59.0 | -49.7 | 13.0 | 0.093 | 0.0 |
HOH |
3.189 |
HG1 |
O |
||
| 5wrd | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2017-03-29 | THR | A:118 | A:118 | 106.0 | 0.757 | -140.5 | 129.9 | 106.0 | 0.757 | 0.0 |
HOH |
6.705 |
CA |
O |
|||
| THR | B:118 | B:118 | 44.0 | 0.314 | T | -78.2 | -32.4 | NA | NA | NA | |||||||||||||
| 5yiq | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2018-05-23 | THR | A:118 | A:118 | 115.0 | 0.821 | -81.2 | 156.4 | 115.0 | 0.821 | 0.0 | |||||||
| 5yis | 1 | Q9CQV6 | 94.4 | 2e-85 |
X-RAY |
2018-05-23 | THR | A:118 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | B:118 | B:118 | 29.0 | 0.207 | H | -71.9 | -49.1 | NA | NA | NA | |||||||||||||
| 2n9x | 1 | Q9GZQ8 | 99.17 | 4e-85 |
NMR |
2016-12-14 | THR | A:118 | A:118 | 112.0 | 0.8 | -141.8 | 151.0 | 112.0 | 0.8 | 0.0 | |||||||
| 2z0e | 2 | Q62625 | 95.16 | 8e-85 |
X-RAY |
2007-05-22 | THR | B:123 | B:118 | 127.0 | 0.907 | -108.9 | 161.3 | 53.0 | 0.379 | 0.528 |
A:Q9Y4P1:0.529 |
HOH |
2.800 |
O |
O |
||
| 2zzp | 2 | Q62625 | 95.16 | 8e-85 |
X-RAY |
2009-03-03 | THR | B:123 | B:118 | 125.0 | 0.893 | -108.9 | 157.2 | 52.0 | 0.371 | 0.522 |
A:Q9Y4P1:0.521 |
HOH |
4.777 |
O |
O |
||
| 6j04 | 1 | Q9GZQ8 | 98.39 | 8e-85 |
X-RAY |
2019-11-06 | THR | A:118 | A:118 | 23.0 | 0.164 | H | -63.3 | -41.5 | 23.0 | 0.164 | 0.0 |
HOH |
2.576 |
OG1 |
O |
||
| THR | B:118 | B:118 | 48.0 | 0.343 | H | -53.6 | -33.5 | NA | NA | NA | |||||||||||||
| THR | C:118 | C:118 | 11.0 | 0.079 | H | -61.7 | -49.6 | NA | NA | NA | |||||||||||||
| THR | D:118 | D:118 | 6.0 | 0.043 | H | -55.9 | -48.6 | NA | NA | NA | |||||||||||||
| 5xad | 1 | Q9GZQ8 | 99.16 | 3e-84 |
X-RAY |
2017-07-12 | THR | A:117 | A:118 | 175.0 | 1.0 | -132.5 | 360.0 | 175.0 | 1.0 | 0.0 |
HOH |
4.191 |
CG2 |
O |
|||
| THR | B:117 | B:118 | 50.0 | 0.357 | G | -59.9 | -25.8 | NA | NA | NA | |||||||||||||
| 2k6q | 1 | Q62625 | 97.5 | 4e-84 |
NMR |
2008-09-02 | THR | A:119 | A:118 | 124.0 | 0.886 | S | -132.5 | 52.8 | 124.0 | 0.886 | 0.0 | ||||||
| 5xac | 1 | Q9GZQ8 | 99.16 | 5e-84 |
X-RAY |
2017-07-12 | THR | A:128 | A:118 | 173.0 | 1.0 | -97.8 | 360.0 | 173.0 | 1.0 | 0.0 |
HOH |
2.302 |
O |
O |
|||
| THR | B:128 | B:118 | 121.0 | 0.864 | 53.5 | 360.0 | 91.0 | 0.65 | 0.214 |
D:Q9GZQ8:0.214 |
HOH |
2.743 |
OG1 |
O |
|||||||||
| THR | C:128 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| THR | D:128 | D:118 | 43.0 | 0.307 | T | -61.3 | -24.3 | 43.0 | 0.307 | 0.0 |
HOH |
2.695 |
OG1 |
O |
|||||||||
| 5xae | 1 | Q9GZQ8 | 99.16 | 6e-84 |
X-RAY |
2017-07-12 | THR | A:140 | A:116 | 105.0 | 0.75 | -126.6 | 163.4 | 105.0 | 0.75 | 0.0 |
HOH |
4.894 |
N |
O |
|||
| THR | B:140 | B:116 | 88.0 | 0.629 | -123.4 | 172.8 | 88.0 | 0.629 | 0.0 |
HOH |
5.581 |
OG1 |
O |
||||||||||
| THR | C:140 | C:116 | 110.0 | 0.786 | -127.2 | 161.1 | 110.0 | 0.786 | 0.0 |
HOH |
3.291 |
C |
O |
||||||||||
| THR | D:140 | D:116 | 111.0 | 0.793 | -130.2 | 163.1 | 111.0 | 0.793 | 0.0 |
HOH |
6.137 |
N |
O |
||||||||||
| 1ugm | 1 | Q62625 | 97.5 | 7e-84 |
X-RAY |
2004-07-06 | THR | A:123 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2z0d | 2 | Q62625 | 97.5 | 7e-84 |
X-RAY |
2007-05-22 | THR | B:123 | B:118 | 123.0 | 0.879 | -109.4 | 159.7 | 55.0 | 0.393 | 0.486 |
A:Q9Y4P1:0.486 |
HOH |
2.779 |
O |
O |
||
| 5ms2 | 2 | Q9GZQ8 | 99.16 | 2e-83 |
X-RAY |
2017-04-19 | THR | B:123 | B:118 | 65.0 | 0.464 | -48.7 | 145.2 | 65.0 | 0.464 | 0.0 |
HOH |
9.428 |
N |
O |
|||
| 5v4k | 1 | Q9GZQ8 | 99.15 | 3e-83 |
X-RAY |
2017-05-17 | THR | A:131 | A:1118 | 127.0 | 0.907 | 60.9 | 360.0 | 127.0 | 0.907 | 0.0 |
HOH |
5.087 |
N |
O |
|||
| THR | B:131 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3vtw | 1 | Q96CV9,Q9GZQ8 | 99.15 | 4e-83 |
X-RAY |
2013-06-26 | THR | A:148 | A:133 | 110.0 | 0.786 | -125.6 | 173.5 | 110.0 | 0.786 | 0.0 |
HOH |
3.720 |
N |
O |
|||
| THR | B:148 | B:133 | 107.0 | 0.764 | -111.8 | 124.7 | NA | NA | NA | ||||||||||||||
| THR | C:148 | C:133 | 123.0 | 0.879 | -136.1 | 162.7 | NA | NA | NA | ||||||||||||||
| 3wao | 1 | O75143,Q9GZQ8 | 99.15 | 5e-83 |
X-RAY |
2013-12-25 | THR | A:133 | A:134 | 108.0 | 0.771 | -137.0 | 153.4 | 108.0 | 0.771 | 0.0 | |||||||
| THR | B:133 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| THR | C:133 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| THR | D:133 | D:134 | 166.0 | 1.0 | -158.6 | 360.0 | NA | NA | NA | ||||||||||||||
| 3x0w | 1 | Q9GZQ8 | 99.15 | 6e-83 |
X-RAY |
2015-01-14 | THR | A:133 | A:145 | 124.0 | 0.886 | -150.6 | 360.0 | 124.0 | 0.886 | 0.0 |
HOH |
9.542 |
N |
O |
|||
| THR | B:133 | B:145 | 119.0 | 0.85 | -126.9 | 360.0 | NA | NA | NA | ||||||||||||||
| 3vtu | 1 | Q9GZQ8 | 98.32 | 7e-83 |
X-RAY |
2013-06-26 | THR | A:122 | A:122 | 118.0 | 0.843 | -123.7 | 147.2 | 118.0 | 0.843 | 0.0 |
HOH |
3.157 |
OG1 |
O |
|||
| 7elg | 1 | Q9GZQ8 | 98.32 | 7e-83 |
X-RAY |
2021-10-13 | THR | A:122 | A:122 | 122.0 | 0.871 | -131.0 | 147.6 | 122.0 | 0.871 | 0.0 |
HOH |
4.729 |
N |
O |
|||
| 5dcn | 1 | Q9GZQ8 | 99.15 | 8e-83 |
X-RAY |
2016-03-09 | THR | A:125 | A:118 | 100.0 | 0.714 | -78.0 | -58.0 | 100.0 | 0.714 | 0.0 |
SO4 HOH |
9.963 4.772 |
O CG2 |
O3 O |
|||
| 4waa | 1 | Q9GZQ8 | 99.15 | 8e-83 |
X-RAY |
2015-09-09 | THR | A:133 | A:134 | 104.0 | 0.743 | 58.2 | 360.0 | 104.0 | 0.743 | 0.0 |
HOH |
8.502 |
OG1 |
O |
|||
| THR | B:133 | B:134 | 139.0 | 0.993 | 56.5 | 360.0 | 139.0 | 0.993 | 0.0 |
HOH |
8.890 |
CB |
O |
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| 3vtv | 1 | Q96CV9,Q9GZQ8 | 99.15 | 9e-83 |
X-RAY |
2013-06-26 | THR | A:133 | A:133 | 117.0 | 0.836 | -132.9 | 144.9 | 117.0 | 0.836 | 0.0 |
HOH |
2.801 |
N |
O |
|||
| 5ms5 | 1 | Q5ZUV9,Q9GZQ8 | 99.15 | 1e-82 |
X-RAY |
2017-04-19 | THR | A:136 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | B:136 | B:118 | 98.0 | 0.7 | 157.8 | 360.0 | NA | NA | NA | ||||||||||||||
| 5ms6 | 1 | Q9GZQ8 | 99.15 | 1e-82 |
X-RAY |
2017-04-19 | THR | A:136 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | B:136 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 2lue | 1 | Q9GZQ8 | 99.13 | 9e-81 |
NMR |
2013-07-17 | THR | A:118 | A:118 | 117.0 | 0.836 | -139.6 | 133.7 | 117.0 | 0.836 | 0.0 | |||||||
| 7r9w | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | THR | A:120 | A:118 | 142.0 | 1.0 | 31.1 | 360.0 | 142.0 | 1.0 | 0.0 |
HOH |
5.880 |
CG2 |
O |
|||
| 7r9z | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | THR | A:120 | A:118 | 143.0 | 1.0 | 34.0 | 360.0 | 143.0 | 1.0 | 0.0 |
HOH |
6.922 |
O |
O |
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| 7ra0 | 1 | Q9H492 | 81.67 | 1e-70 |
X-RAY |
2022-01-12 | THR | A:120 | A:118 | 142.0 | 1.0 | 54.0 | 360.0 | 142.0 | 1.0 | 0.0 |
HOH |
4.341 |
N |
O |
|||
| 5cx3 | 1 | Q9H492 | 80.99 | 1e-70 |
X-RAY |
2016-08-03 | THR | A:118 | A:118 | 56.0 | 0.4 | G | -57.7 | -32.7 | 43.0 | 0.307 | 0.093 |
C:Q9H492:0.093 |
HOH |
8.104 |
O |
O |
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| THR | B:118 | B:118 | 53.0 | 0.379 | G | -57.3 | -30.4 | NA | NA | NA | |||||||||||||
| THR | C:118 | C:118 | 76.0 | 0.543 | G | -55.6 | -29.1 | 34.0 | 0.243 | 0.3 |
A:Q9H492:0.3 |
HOH |
2.837 |
O |
O |
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| THR | D:118 | D:118 | 60.0 | 0.429 | G | -53.1 | -32.8 | NA | NA | NA | |||||||||||||
| 3eci | 1 | Q9H492 | 80.99 | 1e-70 |
X-RAY |
2008-10-14 | THR | A:119 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | B:119 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3wal | 1 | Q9H492 | 80.17 | 1e-69 |
X-RAY |
2013-12-25 | THR | A:122 | A:122 | 86.0 | 0.614 | -78.7 | -38.8 | 86.0 | 0.614 | 0.0 |
HOH |
5.412 |
N |
O |
|||
| 3wan | 1 | O75143,Q9H492 | 80.83 | 1e-69 |
X-RAY |
2013-12-25 | THR | A:133 | A:134 | 16.0 | 0.114 | -148.4 | 105.9 | 16.0 | 0.114 | 0.0 |
HOH |
3.201 |
O |
O |
|||
| THR | B:133 | B:134 | 59.0 | 0.421 | 73.7 | -53.3 | 1.0 | 0.007 | 0.414 |
A:O75143+Q9H492:0.414 |
HOH |
2.877 |
N |
O |
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| 5dpr | 1 | Q9Y4G2,Q9H492 | 80.83 | 2e-69 |
X-RAY |
2016-09-28 | THR | A:133 | A:129 | 151.0 | 1.0 | -138.0 | 360.0 | 151.0 | 1.0 | 0.0 | |||||||
| THR | B:133 | B:129 | 45.0 | 0.321 | T | -76.3 | -42.9 | NA | NA | NA | |||||||||||||
| THR | C:133 | C:129 | 48.0 | 0.343 | T | -76.9 | -43.3 | NA | NA | NA | |||||||||||||
| THR | D:133 | D:129 | 144.0 | 1.0 | 106.3 | 360.0 | NA | NA | NA | ||||||||||||||
| 4zdv | 1 | Q9H492 | 81.51 | 2e-69 |
X-RAY |
2015-06-03 | THR | A:130 | A:118 | 112.0 | 0.8 | -127.5 | 138.7 | 112.0 | 0.8 | 0.0 |
HOH |
3.394 |
N |
O |
|||
| 6tbe | 1 | Q9H492 | 81.03 | 4e-67 |
X-RAY |
2020-11-18 | THR | A:118 | A:122 | 174.0 | 1.0 | -126.2 | 360.0 | 174.0 | 1.0 | 0.0 |
HOH |
3.898 |
O |
O |
|||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-a6nce7-f1 | 1 | A6NCE7 | 100.0 | 1e-90 | THR | A:118 | A:118 | 22.0 | 0.157 | H | -65.8 | -43.3 | |
| af-q9gzq8-f1 | 1 | Q9GZQ8 | 99.2 | 5e-89 | THR | A:118 | A:118 | 12.0 | 0.086 | H | -64.3 | -41.8 | |
| af-q9h492-f1 | 1 | Q9H492 | 80.99 | 5e-71 | THR | A:118 | A:118 | 46.0 | 0.329 | H | -68.0 | -25.2 | |