Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 3129875 | . | C | A | CCDS31729.1:NM_003213.3:c.659gCc>gAc_NP_003204.2:p.220A>D | Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6ge3 | 1 | Q15561 | 100.0 | 3e-166 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 8.0 | 0.07 | B | -148.6 | 127.0 | 8.0 | 0.07 | 0.0 |
HOH |
3.994 |
CB |
O |
||
| 6gec | 1 | Q15561 | 100.0 | 3e-166 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 11.0 | 0.096 | B | -146.9 | 126.5 | 11.0 | 0.096 | 0.0 |
HOH |
2.634 |
O |
O |
||
| 6ge5 | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 6.0 | 0.052 | B | -146.0 | 132.2 | 6.0 | 0.052 | 0.0 |
HOH |
4.061 |
CB |
O |
||
| 6geg | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 4.0 | 0.035 | B | -146.4 | 130.7 | 4.0 | 0.035 | 0.0 |
HOH |
3.916 |
CB |
O |
||
| 6gek | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 11.0 | 0.096 | B | -155.6 | 123.3 | 11.0 | 0.096 | 0.0 |
HOH |
5.329 |
N |
O |
||
| ALA | C:5 | B:220 | 12.0 | 0.104 | B | -155.8 | 130.0 | NA | NA | NA | |||||||||||||
| 6hik | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2019-04-03 | ALA | A:5 | A:220 | 17.0 | 0.148 | E | -148.2 | 133.2 | 17.0 | 0.148 | 0.0 |
HOH |
2.588 |
O |
O |
||
| 6ge4 | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 20.0 | 0.174 | B | -146.7 | 132.7 | 20.0 | 0.174 | 0.0 |
HOH |
3.974 |
O |
O |
||
| 6gee | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 10.0 | 0.087 | B | -150.7 | 129.2 | 10.0 | 0.087 | 0.0 |
HOH |
2.702 |
O |
O |
||
| 5oaq | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2017-10-11 | ALA | A:6 | A:220 | 13.0 | 0.113 | B | -148.8 | 127.1 | 13.0 | 0.113 | 0.0 |
HOH |
4.802 |
O |
O |
||
| 6q2x | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2019-07-03 | ALA | A:6 | A:220 | 13.0 | 0.113 | B | -148.8 | 125.4 | 13.0 | 0.113 | 0.0 |
HOH |
4.907 |
O |
O |
||
| 6q36 | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2019-07-03 | ALA | A:6 | A:220 | 13.0 | 0.113 | B | -154.2 | 127.9 | 13.0 | 0.113 | 0.0 |
HOH |
3.786 |
CB |
O |
||
| ALA | B:6 | B:220 | 17.0 | 0.148 | B | -145.1 | 130.6 | 17.0 | 0.148 | 0.0 |
HOH |
5.399 |
N |
O |
|||||||||
| 6ge6 | 1 | Q15561 | 99.09 | 1e-164 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 24.0 | 0.209 | E | -144.9 | 130.8 | 24.0 | 0.209 | 0.0 |
HOH |
2.905 |
O |
O |
||
| 6gei | 1 | Q15561 | 99.09 | 1e-164 |
X-RAY |
2018-09-19 | ALA | A:5 | A:220 | 26.0 | 0.226 | E | -148.5 | 132.5 | 26.0 | 0.226 | 0.0 |
HOH |
2.718 |
O |
O |
||
| 6sen | 1 | Q15561 | 99.54 | 5e-164 |
X-RAY |
2019-11-20 | ALA | A:6 | A:220 | 32.0 | 0.278 | E | -148.2 | 127.5 | 32.0 | 0.278 | 0.0 |
HOH |
4.013 |
O |
O |
||
| ALA | B:6 | B:220 | 25.0 | 0.217 | B | -150.4 | 133.5 | NA | NA | NA | |||||||||||||
| 6seo | 1 | Q15561 | 99.54 | 5e-164 |
X-RAY |
2019-11-20 | ALA | A:6 | A:220 | 29.0 | 0.252 | E | -141.6 | 134.0 | 29.0 | 0.252 | 0.0 |
HOH |
5.032 |
O |
O |
||
| 4ln0 | 1 | Q62296 | 96.35 | 3e-161 |
X-RAY |
2014-02-26 | ALA | A:8 | A:213 | 1.0 | 0.009 | B | -155.1 | 132.3 | 1.0 | 0.009 | 0.0 |
HOH |
9.828 |
CB |
O |
||
| ALA | B:8 | B:213 | 27.0 | 0.235 | B | -150.4 | 132.1 | 27.0 | 0.235 | 0.0 | |||||||||||||
| 6l9f | 1 | Q62296 | 96.35 | 3e-161 |
X-RAY |
2019-12-11 | ALA | A:8 | A:213 | 31.0 | 0.27 | B | -148.1 | 130.7 | 31.0 | 0.27 | 0.0 |
HOH |
5.519 |
N |
O |
||
| ALA | C:8 | B:213 | 0.0 | 0.0 | B | -168.1 | 133.3 | NA | NA | NA | |||||||||||||
| 6sba | 1 | Q62296 | 96.35 | 9e-161 |
X-RAY |
2020-09-30 | ALA | A:7 | A:213 | 25.0 | 0.217 | E | -151.4 | 129.9 | 25.0 | 0.217 | 0.0 |
HOH |
4.212 |
H |
O |
||
| 3jua | 1 | Q62296 | 96.33 | 2e-160 |
X-RAY |
2010-02-23 | ALA | A:6 | A:213 | 10.0 | 0.087 | B | -158.2 | 152.4 | 10.0 | 0.087 | 0.0 |
HOH |
3.960 |
O |
O |
||
| ALA | C:6 | C:213 | 6.0 | 0.052 | B | -155.5 | 134.0 | NA | NA | NA | |||||||||||||
| ALA | E:6 | E:213 | 9.0 | 0.078 | B | -121.5 | 158.6 | NA | NA | NA | |||||||||||||
| ALA | G:6 | G:213 | 10.0 | 0.087 | B | -127.5 | 163.7 | NA | NA | NA | |||||||||||||
| 5xjd | 1 | Q62296 | 96.33 | 2e-160 |
X-RAY |
2018-01-24 | ALA | A:6 | A:213 | 24.0 | 0.209 | B | -152.2 | 133.9 | 24.0 | 0.209 | 0.0 |
HOH |
4.139 |
CB |
O |
||
| ALA | B:6 | B:213 | 22.0 | 0.191 | B | -154.0 | 135.7 | 22.0 | 0.191 | 0.0 |
HOH |
5.451 |
CB |
O |
|||||||||
| 5gn0 | 1 | Q62296 | 96.33 | 4e-160 |
X-RAY |
2017-05-31 | ALA | A:11 | A:213 | 0.0 | 0.0 | B | -166.3 | 141.1 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:11 | B:213 | 0.0 | 0.0 | B | -142.0 | 155.9 | NA | NA | NA | |||||||||||||
| ALA | C:11 | C:213 | 0.0 | 0.0 | B | -144.0 | 135.5 | NA | NA | NA | |||||||||||||
| ALA | D:11 | D:213 | 3.0 | 0.026 | B | -148.7 | 138.8 | NA | NA | NA | |||||||||||||
| 5z2q | 3 | Q62296 | 96.31 | 1e-159 |
X-RAY |
2018-01-31 | ALA | C:13 | A:213 | 2.0 | 0.017 | B | -167.7 | 149.7 | NA | NA | NA | ||||||
| 5z2q | 4 | Q62296 | 96.31 | 2e-159 |
X-RAY |
2018-01-31 | ALA | D:15 | B:213 | 1.0 | 0.009 | B | -171.5 | 150.2 | 1.0 | 0.009 | 0.0 | ||||||
| 7cmm | 1 | P28347 | 81.45 | 8e-139 |
X-RAY |
2021-02-03 | GLY | A:16 | A:212 | 27.0 | 0.36 | B | -175.0 | 154.2 | 27.0 | 0.36 | 0.0 | ||||||
| GLY | B:16 | B:212 | 16.0 | 0.213 | B | -149.1 | 160.9 | NA | NA | NA | |||||||||||||
| GLY | C:16 | C:212 | 21.0 | 0.28 | B | -176.9 | 149.7 | NA | NA | NA | |||||||||||||
| GLY | D:16 | D:212 | 22.0 | 0.293 | B | -146.9 | 161.1 | NA | NA | NA | |||||||||||||
| 4re1 | 1 | P28347 | 81.28 | 2e-137 |
X-RAY |
2014-11-19 | GLY | A:6 | A:197 | 23.0 | 0.307 | B | 176.0 | 165.1 | 23.0 | 0.307 | 0.0 |
HOH |
2.950 |
O |
O |
||
| GLY | B:6 | B:197 | 12.0 | 0.16 | B | 174.0 | 168.1 | NA | NA | NA | |||||||||||||
| 6hil | 1 | P28347 | 81.65 | 4e-137 |
X-RAY |
2019-04-03 | GLY | A:5 | A:197 | 25.0 | 0.333 | B | 145.3 | 160.0 | 25.0 | 0.333 | 0.0 |
HOH |
4.248 |
N |
O |
||
| GLY | C:5 | D:197 | 25.0 | 0.333 | B | 138.5 | 174.4 | NA | NA | NA | |||||||||||||
| GLY | E:5 | B:197 | 17.0 | 0.227 | B | 116.5 | 146.2 | NA | NA | NA | |||||||||||||
| GLY | G:5 | C:197 | 20.0 | 0.267 | B | 154.5 | 154.3 | NA | NA | NA | |||||||||||||
| 3kys | 1 | P28347 | 81.65 | 4e-137 |
X-RAY |
2010-02-23 | GLY | A:5 | A:197 | 14.0 | 0.187 | S | 99.7 | 165.2 | 14.0 | 0.187 | 0.0 | ||||||
| GLY | C:5 | C:197 | 6.0 | 0.08 | E | 145.1 | -156.9 | NA | NA | NA | |||||||||||||
| 6im5 | 1 | P28347 | 81.36 | 2e-136 |
X-RAY |
2019-02-06 | GLY | A:19 | A:212 | 11.0 | 0.147 | B | 166.0 | 138.6 | 11.0 | 0.147 | 0.0 |
HOH |
3.828 |
O |
O |
||
| GLY | B:19 | B:212 | 19.0 | 0.253 | B | -161.5 | 158.7 | NA | NA | NA | |||||||||||||
| 7li5 | 1 | E9PKB7 | 81.94 | 6e-136 |
X-RAY |
2022-02-02 | GLY | A:8 | A:212 | 44.0 | 0.587 | 85.0 | -174.2 | 44.0 | 0.587 | 0.0 |
HOH |
6.537 |
O |
O |
|||
| GLY | B:8 | B:212 | 48.0 | 0.64 | 80.1 | -154.4 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q15561-f1 | 1 | Q15561 | 100.0 | 0.0 | ALA | A:220 | A:220 | 4.0 | 0.035 | B | -137.9 | 126.7 | |