Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3131016 . A C CCDS31729.1:NM_003213.3:c.730Aag>Cag_NP_003204.2:p.244K>Q Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 LYS A:29 A:244 115.0 0.575 E -115.6 124.4 115.0 0.575 0.0 HOH
 3.275
 NZ
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 LYS A:29 A:244 130.0 0.65 E -113.0 125.1 130.0 0.65 0.0 HOH
 3.297
 CB
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 LYS A:29 A:244 114.0 0.57 E -121.9 129.5 114.0 0.57 0.0 HOH
 2.798
 NZ
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 LYS A:29 A:244 114.0 0.57 E -123.7 127.1 114.0 0.57 0.0 HOH
 2.962
 NZ
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 LYS A:29 A:244 124.0 0.62 E -113.1 125.5 124.0 0.62 0.0 HOH
 2.801
 NZ
 O
LYS C:29 B:244 138.0 0.69 E -122.6 119.4 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 LYS A:29 A:244 107.0 0.535 E -113.9 123.6 107.0 0.535 0.0 HOH
 2.798
 NZ
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 LYS A:29 A:244 111.0 0.555 E -118.8 123.7 111.0 0.555 0.0 HOH
 3.453
 CB
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 LYS A:29 A:244 118.0 0.59 E -110.1 125.1 118.0 0.59 0.0 HOH
 2.834
 NZ
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 LYS A:30 A:244 119.0 0.595 E -119.9 126.5 119.0 0.595 0.0 HOH
 3.461
 CB
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 LYS A:30 A:244 113.0 0.565 E -116.2 126.4 113.0 0.565 0.0 HOH
 3.318
 NZ
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 LYS A:30 A:244 121.0 0.605 E -122.0 129.7 56.0 0.28 0.325 B:Q15561:0.325
 PO4
PO4
HOH
 3.893
4.050
4.011
 NZ
NZ
CE
 O1
O2
O
LYS B:30 B:244 113.0 0.565 E -119.1 130.3 51.0 0.255 0.31 A:Q15561:0.31
 PO4
PO4
HOH
 7.219
2.784
3.813
 NZ
NZ
NZ
 O3
O3
O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 LYS A:29 A:244 104.0 0.52 E -116.3 123.7 104.0 0.52 0.0 PO4
PO4
HOH
 3.249
9.525
2.723
 NZ
NZ
NZ
 O2
O1
O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 LYS A:29 A:244 116.0 0.58 E -114.0 124.9 116.0 0.58 0.0 HOH
 2.842
 NZ
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 LYS A:30 A:244 125.0 0.625 E -122.7 130.2 125.0 0.625 0.0 HOH
 2.814
 NZ
 O
LYS B:30 B:244 107.0 0.535 E -125.6 129.3 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 LYS A:30 A:244 126.0 0.63 E -117.5 126.7 126.0 0.63 0.0 HOH
 7.562
 CE
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 LYS A:32 A:237 111.0 0.555 E -129.0 144.0 111.0 0.555 0.0
LYS B:32 B:237 151.0 0.755 360.0 141.5 151.0 0.755 0.0
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 LYS A:32 A:237 117.0 0.585 E -132.2 130.3 117.0 0.585 0.0 HOH
 2.850
 NZ
 O
LYS C:32 B:237 112.0 0.56 E -122.9 126.3 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 LYS A:31 A:237 95.0 0.475 -95.3 165.4 95.0 0.475 0.0 GOL
HOH
 4.122
2.462
 O
HE3
 O2
O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 LYS A:30 A:237 45.0 0.225 E -90.0 120.5 45.0 0.225 0.0 HOH
 3.480
 O
 O
LYS C:30 C:237 71.0 0.355 E -91.3 107.0 NA NA NA
LYS E:30 E:237 76.0 0.38 E -109.7 118.0 NA NA NA
LYS G:30 G:237 59.0 0.295 E -112.8 125.9 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 LYS A:30 A:237 88.0 0.44 E -121.4 105.9 88.0 0.44 0.0 HOH
 5.646
 C
 O
LYS B:30 B:237 97.0 0.485 E -119.9 106.3 97.0 0.485 0.0 HOH
 7.838
 O
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 LYS A:35 A:237 101.0 0.505 E -129.3 124.1 101.0 0.505 0.0 HOH
 7.383
 NZ
 O
LYS B:35 B:237 113.0 0.565 E -138.3 117.4 NA NA NA
LYS C:35 C:237 98.0 0.49 E -132.0 124.5 NA NA NA
LYS D:35 D:237 117.0 0.585 E -132.1 131.4 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 LYS C:37 A:237 97.0 0.485 E -115.3 142.5 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 LYS D:39 B:237 118.0 0.59 E -111.5 153.7 118.0 0.59 0.0 HOH
 4.729
 NZ
 O
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 LYS A:40 A:236 104.0 0.52 E -113.9 120.5 104.0 0.52 0.0
LYS B:40 B:236 59.0 NA E -130.7 115.1 NA NA NA
LYS C:40 C:236 95.0 0.475 E -114.1 122.0 NA NA NA
LYS D:40 D:236 151.0 0.755 360.0 111.5 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 LYS A:30 A:221 97.0 0.485 E -134.0 127.1 97.0 0.485 0.0 HOH
 2.780
 NZ
 O
LYS B:30 B:221 100.0 0.5 E -130.0 127.3 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 LYS A:29 A:221 115.0 0.575 E -120.2 127.8 115.0 0.575 0.0 HOH
 3.200
 CE
 O
LYS C:29 D:221 115.0 0.575 E -133.0 124.9 NA NA NA
LYS E:29 B:221 129.0 0.645 E -123.6 120.8 NA NA NA
LYS G:29 C:221 105.0 0.525 E -133.0 117.0 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 LYS A:29 A:221 98.0 0.49 E -131.4 131.6 98.0 0.49 0.0 HOH
 5.173
 NZ
 O
LYS C:29 C:221 98.0 0.49 E -132.9 129.6 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 LYS A:43 A:236 104.0 0.52 E -126.8 127.8 104.0 0.52 0.0 HOH
 2.859
 NZ
 O
LYS B:43 B:236 113.0 0.565 E -122.9 129.8 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 LYS A:32 A:236 98.0 0.49 E -126.0 129.8 98.0 0.49 0.0 HOH
 3.214
 NZ
 O
LYS B:32 B:236 103.0 0.515 E -123.5 128.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 LYS A:244 A:244 104.0 0.52 E -114.2 117.8