Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3131029 . T A CCDS31729.1:NM_003213.3:c.743gTg>gAg_NP_003204.2:p.248V>E Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 VAL A:33 A:248 9.0 0.058 E -143.5 153.2 9.0 0.058 0.0 MYR
HOH
 3.987
3.830
 CG2
CA
 C8
O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 VAL A:33 A:248 7.0 0.045 E -142.4 151.0 7.0 0.045 0.0 MYR
HOH
 4.156
3.663
 CG2
CA
 C10
O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 VAL A:33 A:248 7.0 0.045 E -144.7 155.0 7.0 0.045 0.0 MYR
HOH
 3.935
3.479
 CG2
CA
 C10
O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 VAL A:33 A:248 8.0 0.052 E -141.1 156.5 8.0 0.052 0.0 MYR
HOH
 4.006
3.807
 CG2
CA
 C10
O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 VAL A:33 A:248 4.0 0.026 E -148.5 154.6 4.0 0.026 0.0 MYR
HOH
 3.855
3.776
 CG2
CA
 C10
O
VAL C:33 B:248 7.0 0.045 E -139.5 149.3 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 VAL A:33 A:248 7.0 0.045 E -143.9 153.1 7.0 0.045 0.0 MYR
PO4
HOH
 3.995
6.814
3.556
 CG2
C
CA
 C10
O2
O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 VAL A:33 A:248 7.0 0.045 E -144.4 152.1 7.0 0.045 0.0 MYR
HOH
 3.983
3.786
 CG2
CA
 C10
O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 VAL A:33 A:248 7.0 0.045 E -141.8 152.6 7.0 0.045 0.0 MYR
HOH
 3.995
3.720
 CG2
CA
 C10
O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 VAL A:34 A:248 8.0 0.052 E -145.2 154.2 8.0 0.052 0.0 MYR
HOH
 3.985
3.927
 CG2
CA
 C10
O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 VAL A:34 A:248 7.0 0.045 E -140.8 153.2 7.0 0.045 0.0 MYR
HOH
 4.196
3.662
 CG2
CA
 C10
O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 VAL A:34 A:248 6.0 0.039 E -136.5 157.7 6.0 0.039 0.0 MYR
PO4
HOH
 4.011
9.823
3.742
 CG2
O
CA
 C10
O1
O
VAL B:34 B:248 7.0 0.045 E -144.6 154.7 7.0 0.045 0.0 MYR
PO4
HOH
 3.978
6.528
3.619
 CG2
C
CA
 C10
O4
O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 VAL A:33 A:248 6.0 0.039 E -142.3 153.9 6.0 0.039 0.0 MYR
PO4
PO4
HOH
 4.041
6.653
9.285
3.645
 CG2
C
O
CA
 C10
O2
O2
O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 VAL A:33 A:248 7.0 0.045 E -143.9 151.5 7.0 0.045 0.0 MYR
PO4
HOH
 4.149
6.781
3.563
 CG2
C
CA
 C9
O2
O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 VAL A:34 A:248 0.0 0.0 E -147.1 154.1 0.0 0.0 0.0 SO4
HOH
 6.647
3.611
 C
CA
 O3
O
VAL B:34 B:248 0.0 0.0 E -146.0 153.7 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 VAL A:34 A:248 0.0 0.0 E -137.6 148.5 0.0 0.0 0.0
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 VAL A:36 A:241 7.0 0.045 E -164.7 128.0 7.0 0.045 0.0 PEG
HOH
 4.761
5.565
 CG1
CG2
 C4
O
VAL B:36 B:241 7.0 0.045 E -164.6 126.6 7.0 0.045 0.0 PEG
 5.000
 CG1
 O1
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 VAL A:36 A:241 0.0 0.0 E -143.5 159.5 0.0 0.0 0.0 ACT
HOH
 4.084
5.362
 C
C
 OXT
O
VAL C:36 B:241 0.0 0.0 E -142.3 147.3 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 VAL A:35 A:241 0.0 0.0 E -143.4 153.3 0.0 0.0 0.0 HOH
 2.909
 HA
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 VAL A:34 A:241 4.0 0.026 E -122.5 166.6 4.0 0.026 0.0 HOH
 4.807
 N
 O
VAL C:34 C:241 5.0 0.032 E -121.8 132.5 NA NA NA
VAL E:34 E:241 4.0 0.026 -64.2 157.7 NA NA NA
VAL G:34 G:241 2.0 0.013 E -145.0 140.4 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 VAL A:34 A:241 7.0 0.045 E -142.0 157.9 7.0 0.045 0.0 HOH
 3.549
 CA
 O
VAL B:34 B:241 11.0 0.071 E -143.2 157.8 11.0 0.071 0.0 HOH
 6.675
 C
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 VAL A:39 A:241 9.0 0.058 E -140.6 148.8 9.0 0.058 0.0 HOH
 9.548
 O
 O
VAL B:39 B:241 8.0 0.052 E -131.7 147.9 NA NA NA
VAL C:39 C:241 8.0 0.052 E -139.0 150.2 NA NA NA
VAL D:39 D:241 7.0 0.045 E -139.1 147.1 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 VAL C:41 A:241 10.0 0.065 E -141.5 155.4 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 VAL D:43 B:241 9.0 0.058 E -138.5 154.0 9.0 0.058 0.0 PO4
 6.192
 C
 O1
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 VAL A:44 A:240 7.0 0.045 E -133.4 148.8 7.0 0.045 0.0 KK9
 3.663
 CG2
 C14
VAL B:44 B:240 5.0 0.032 E -140.7 163.6 NA NA NA
VAL C:44 C:240 8.0 0.052 E -131.9 150.6 NA NA NA
VAL D:44 D:240 9.0 0.058 E -143.6 166.1 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 VAL A:34 A:225 9.0 0.058 E -140.8 160.0 9.0 0.058 0.0 CL
HOH
 6.884
3.878
 C
CA
 CL
O
VAL B:34 B:225 9.0 0.058 E -140.0 158.1 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 VAL A:33 A:225 7.0 0.045 E -141.4 149.5 7.0 0.045 0.0 MYR
HOH
 4.312
3.463
 CG1
CA
 C10
O
VAL C:33 D:225 7.0 0.045 E -147.0 157.9 NA NA NA
VAL E:33 B:225 6.0 0.039 E -142.5 155.8 NA NA NA
VAL G:33 C:225 6.0 0.039 E -140.8 153.1 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 VAL A:33 A:225 1.0 0.006 E -141.1 156.8 1.0 0.006 0.0
VAL C:33 C:225 1.0 0.006 E -142.7 156.0 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 VAL A:47 A:240 8.0 0.052 E -140.4 160.7 8.0 0.052 0.0 PO4
HOH
 6.545
3.566
 C
CA
 O2
O
VAL B:47 B:240 8.0 0.052 E -145.1 159.5 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 VAL A:36 A:240 10.0 0.065 E -146.9 158.8 10.0 0.065 0.0 Y2D
SO4
HOH
 3.409
6.574
3.411
 CG2
C
CA
 H4
O3
O
VAL B:36 B:240 9.0 0.058 E -146.1 156.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 VAL A:248 A:248 7.0 0.045 E -143.6 147.9