Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3131073 . G A CCDS31729.1:NM_003213.3:c.787Gaa>Aaa_NP_003204.2:p.263E>K Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLU A:48 A:263 125.0 0.658 E -68.0 158.8 90.0 0.474 0.184 B:P46937:0.184
 HOH
 2.681
 OE1
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLU A:48 A:263 143.0 0.753 -59.4 144.4 107.0 0.563 0.19 B:P46937:0.189
 HOH
 2.842
 OE1
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLU A:48 A:263 119.0 0.626 -66.7 154.4 81.0 0.426 0.2 B:P46937:0.2
 HOH
 2.601
 OE1
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLU A:48 A:263 120.0 0.632 -70.4 153.6 84.0 0.442 0.19 B:P46937:0.189
 HOH
 2.717
 N
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLU A:48 A:263 118.0 0.621 -69.9 146.3 81.0 0.426 0.195 B:P46937:0.195
 HOH
 2.643
 OE1
 O
GLU C:48 B:263 100.0 0.526 E -65.7 148.9 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 GLU A:48 A:263 146.0 0.768 -90.6 165.5 106.0 0.558 0.21 B:P46937:0.211
 HOH
 3.021
 N
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ALA A:48 A:263 51.0 0.443 -63.6 152.0 42.0 0.365 0.078 B:P46937:0.078
 HOH
 2.815
 N
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ALA A:48 A:263 59.0 0.513 E -69.8 155.0 54.0 0.47 0.043 B:P46937:0.043
 HOH
 3.293
 N
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 GLU A:49 A:263 124.0 0.653 -61.7 156.6 88.0 0.463 0.19 B:P46937:0.189
 HOH
 2.712
 N
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLU A:49 A:263 125.0 0.658 -64.6 155.6 89.0 0.468 0.19 B:P46937:0.189
 HOH
 2.896
 N
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLU A:49 A:263 114.0 0.6 -68.0 159.6 76.0 0.4 0.2 C:None:0.2
 HOH
 2.669
 OE2
 O
GLU B:49 B:263 109.0 0.574 E -71.9 168.5 71.0 0.374 0.2 D:None:0.2
 HOH
 2.542
 OE1
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ALA A:48 A:263 50.0 0.435 -80.9 169.0 40.0 0.348 0.087 B:P46937:0.087
 HOH
 2.747
 N
 O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ALA A:48 A:263 53.0 0.461 -71.8 160.9 45.0 0.391 0.07 B:P46937:0.07
 HOH
 2.784
 N
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLU A:49 A:263 126.0 0.663 -66.5 150.5 85.0 0.447 0.216 C:Q8N9Y4:0.216
 HOH
 2.539
 OE1
 O
GLU B:49 B:263 133.0 0.7 -70.2 156.8 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLU A:49 A:263 105.0 0.553 E -65.5 146.6 62.0 0.326 0.227 B:A6NEQ2:0.226
 HOH
 3.006
 N
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 GLU A:51 A:256 117.0 0.616 E -70.8 160.7 117.0 0.616 0.0 GOL
HOH
 9.321
2.834
 OE2
N
 O2
O
GLU B:51 B:256 113.0 0.595 E -70.3 159.4 113.0 0.595 0.0 GOL
 7.117
 OE1
 O1
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 GLU A:51 A:256 121.0 0.637 -60.0 162.8 83.0 0.437 0.2 B:Q8N9Y4:0.2
 HOH
 2.554
 OE1
 O
GLU C:51 B:256 134.0 0.705 E -67.7 157.2 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 GLU A:50 A:256 107.0 0.563 -101.9 -23.4 107.0 0.563 0.0 GOL
HOH
 8.657
2.281
 C
H
 O3
O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 GLU A:49 A:256 134.0 0.705 -71.0 169.4 88.0 0.463 0.242 B:P46938:0.242
 HOH
 3.300
 OE2
 O
GLU C:49 C:256 115.0 0.605 E -71.4 158.8 NA NA NA
GLU E:49 E:256 119.0 0.626 E -74.5 147.6 NA NA NA
GLU G:49 G:256 117.0 0.616 -45.3 142.2 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 GLU A:49 A:256 114.0 0.6 E -67.2 157.4 114.0 0.6 0.0 HOH
 2.705
 N
 O
GLU B:49 B:256 107.0 0.563 E -68.2 155.6 107.0 0.563 0.0 HOH
 2.779
 N
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 GLU A:54 A:256 115.0 0.605 E -81.5 127.2 76.0 0.4 0.205 E:Q9EPK5:0.205
 HOH
 6.992
 OE1
 O
GLU B:54 B:256 127.0 0.668 E -72.1 155.2 NA NA NA
GLU C:54 C:256 119.0 0.626 E -76.1 173.2 NA NA NA
GLU D:54 D:256 129.0 0.679 E -72.4 155.9 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 GLU C:56 A:256 116.0 0.611 E -69.0 159.6 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 GLU D:58 B:256 114.0 0.6 -61.0 149.4 114.0 0.6 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 GLU A:59 A:255 127.0 0.668 E -69.3 158.6 127.0 0.668 0.0
GLU B:59 B:255 135.0 0.711 -69.7 136.9 NA NA NA
GLU C:59 C:255 99.0 0.521 -73.3 159.1 NA NA NA
GLU D:59 D:255 65.0 0.342 -105.1 132.6 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 GLU A:49 A:240 133.0 0.7 -66.5 160.9 94.0 0.495 0.205 D:P46937:0.205
 HOH
 7.146
 N
 O
GLU B:49 B:240 130.0 0.684 E -71.3 158.6 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 GLU A:48 A:240 171.0 0.9 -52.3 151.0 95.0 0.5 0.4 B:P46937:0.4
 HOH
 7.131
 OE2
 O
GLU C:48 D:240 163.0 0.858 E -60.1 143.6 NA NA NA
GLU E:48 B:240 163.0 0.858 E -54.6 147.5 NA NA NA
GLU G:48 C:240 152.0 0.8 E -58.0 143.0 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 GLU A:48 A:240 126.0 0.663 E -79.9 168.7 92.0 0.484 0.179 B:P46937:0.179
GLU C:48 C:240 122.0 0.642 -78.6 165.5 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 GLU A:62 A:255 73.0 0.384 -74.3 172.6 73.0 0.384 0.0 HOH
 2.601
 OE1
 O
GLU B:62 B:255 71.0 0.374 -71.8 168.5 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 GLU A:51 A:255 75.0 0.395 E -79.1 161.1 75.0 0.395 0.0 HOH
 2.614
 OE1
 O
GLU B:51 B:255 86.0 0.453 E -79.2 161.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 GLU A:263 A:263 112.0 0.589 E -61.2 154.1