Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 3131085 | . | A | C | CCDS31729.1:NM_003213.3:c.799Atc>Ctc_NP_003204.2:p.267I>L | Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6ge3 | 1 | Q15561 | 100.0 | 3e-166 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 0.0 | 0.0 | G | -58.7 | -31.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.486 |
CG2 |
O |
||
| 6gec | 1 | Q15561 | 100.0 | 3e-166 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 1.0 | 0.006 | G | -58.7 | -28.3 | 1.0 | 0.006 | 0.0 |
HOH |
4.329 |
CG2 |
O |
||
| 6ge5 | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 0.0 | 0.0 | G | -59.8 | -29.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.418 |
CG2 |
O |
||
| 6geg | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 1.0 | 0.006 | G | -61.9 | -31.1 | 1.0 | 0.006 | 0.0 |
HOH |
4.334 |
CG2 |
O |
||
| 6gek | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 1.0 | 0.006 | G | -60.7 | -28.8 | 1.0 | 0.006 | 0.0 |
HOH |
4.804 |
CG2 |
O |
||
| ILE | C:52 | B:267 | 1.0 | 0.006 | G | -64.7 | -29.2 | NA | NA | NA | |||||||||||||
| 6hik | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2019-04-03 | ILE | A:52 | A:267 | 0.0 | 0.0 | G | -60.4 | -27.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.588 |
CG2 |
O |
||
| 6ge4 | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 0.0 | 0.0 | G | -62.9 | -24.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.674 |
CG2 |
O |
||
| 6gee | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 1.0 | 0.006 | G | -61.1 | -28.3 | 1.0 | 0.006 | 0.0 |
HOH |
4.459 |
CG2 |
O |
||
| 5oaq | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2017-10-11 | ILE | A:53 | A:267 | 0.0 | 0.0 | G | -59.7 | -31.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.463 |
CG2 |
O |
||
| 6q2x | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2019-07-03 | ILE | A:53 | A:267 | 1.0 | 0.006 | G | -59.2 | -32.3 | 1.0 | 0.006 | 0.0 |
HOH |
4.340 |
CG2 |
O |
||
| 6q36 | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2019-07-03 | ILE | A:53 | A:267 | 1.0 | 0.006 | G | -61.7 | -25.0 | 1.0 | 0.006 | 0.0 |
HOH |
5.458 |
O |
O |
||
| ILE | B:53 | B:267 | 1.0 | 0.006 | G | -62.9 | -23.7 | 1.0 | 0.006 | 0.0 |
HOH |
5.978 |
N |
O |
|||||||||
| 6ge6 | 1 | Q15561 | 99.09 | 1e-164 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 2.0 | 0.011 | G | -59.0 | -28.0 | 2.0 | 0.011 | 0.0 |
HOH |
4.415 |
CG2 |
O |
||
| 6gei | 1 | Q15561 | 99.09 | 1e-164 |
X-RAY |
2018-09-19 | ILE | A:52 | A:267 | 1.0 | 0.006 | G | -60.0 | -26.4 | 1.0 | 0.006 | 0.0 |
HOH |
4.475 |
CG2 |
O |
||
| 6sen | 1 | Q15561 | 99.54 | 5e-164 |
X-RAY |
2019-11-20 | ILE | A:53 | A:267 | 12.0 | 0.069 | G | -62.1 | -27.5 | 12.0 | 0.069 | 0.0 |
HOH |
6.005 |
N |
O |
||
| ILE | B:53 | B:267 | 0.0 | 0.0 | G | -59.7 | -29.9 | NA | NA | NA | |||||||||||||
| 6seo | 1 | Q15561 | 99.54 | 5e-164 |
X-RAY |
2019-11-20 | ILE | A:53 | A:267 | 2.0 | 0.011 | G | -53.5 | -32.7 | 2.0 | 0.011 | 0.0 | ||||||
| 4ln0 | 1 | Q62296 | 96.35 | 3e-161 |
X-RAY |
2014-02-26 | ILE | A:55 | A:260 | 0.0 | 0.0 | G | -64.6 | -21.8 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:55 | B:260 | 0.0 | 0.0 | G | -64.7 | -20.0 | 0.0 | 0.0 | 0.0 |
GOL |
8.899 |
N |
O2 |
|||||||||
| 6l9f | 1 | Q62296 | 96.35 | 3e-161 |
X-RAY |
2019-12-11 | ILE | A:55 | A:260 | 0.0 | 0.0 | G | -62.4 | -23.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.113 |
N |
O |
||
| ILE | C:55 | B:260 | 0.0 | 0.0 | G | -55.4 | -29.4 | NA | NA | NA | |||||||||||||
| 6sba | 1 | Q62296 | 96.35 | 9e-161 |
X-RAY |
2020-09-30 | ILE | A:54 | A:260 | 3.0 | 0.017 | G | -53.0 | -27.1 | 3.0 | 0.017 | 0.0 |
GOL GOL HOH |
7.097 9.857 5.759 |
HA O O |
H11 H11 O |
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| 3jua | 1 | Q62296 | 96.33 | 2e-160 |
X-RAY |
2010-02-23 | ILE | A:53 | A:260 | 0.0 | 0.0 | G | -46.6 | -28.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.936 |
N |
O |
||
| ILE | C:53 | C:260 | 0.0 | 0.0 | G | -36.8 | -46.7 | NA | NA | NA | |||||||||||||
| ILE | E:53 | E:260 | 0.0 | 0.0 | G | -53.5 | -37.7 | NA | NA | NA | |||||||||||||
| ILE | G:53 | G:260 | 0.0 | 0.0 | G | -58.1 | -26.1 | NA | NA | NA | |||||||||||||
| 5xjd | 1 | Q62296 | 96.33 | 2e-160 |
X-RAY |
2018-01-24 | ILE | A:53 | A:260 | 0.0 | 0.0 | G | -63.0 | -26.2 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:53 | B:260 | 0.0 | 0.0 | G | -57.2 | -27.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.061 |
N |
O |
|||||||||
| 5gn0 | 1 | Q62296 | 96.33 | 4e-160 |
X-RAY |
2017-05-31 | ILE | A:58 | A:260 | 2.0 | 0.011 | G | -63.5 | -31.1 | 2.0 | 0.011 | 0.0 | ||||||
| ILE | B:58 | B:260 | 4.0 | 0.023 | G | -63.4 | -25.2 | NA | NA | NA | |||||||||||||
| ILE | C:58 | C:260 | 1.0 | 0.006 | G | -62.0 | -20.6 | NA | NA | NA | |||||||||||||
| ILE | D:58 | D:260 | 3.0 | 0.017 | G | -63.7 | -26.9 | NA | NA | NA | |||||||||||||
| 5z2q | 3 | Q62296 | 96.31 | 1e-159 |
X-RAY |
2018-01-31 | ILE | C:60 | A:260 | 0.0 | 0.0 | G | -65.0 | -33.9 | NA | NA | NA | ||||||
| 5z2q | 4 | Q62296 | 96.31 | 2e-159 |
X-RAY |
2018-01-31 | ILE | D:62 | B:260 | 0.0 | 0.0 | G | -62.7 | -37.2 | 0.0 | 0.0 | 0.0 | ||||||
| 7cmm | 1 | P28347 | 81.45 | 8e-139 |
X-RAY |
2021-02-03 | ILE | A:63 | A:259 | 0.0 | 0.0 | G | -67.8 | -24.5 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | B:63 | B:259 | 0.0 | 0.0 | G | -72.7 | -35.3 | NA | NA | NA | |||||||||||||
| ILE | C:63 | C:259 | 12.0 | 0.069 | G | -63.7 | -24.3 | NA | NA | NA | |||||||||||||
| ILE | D:63 | D:259 | 2.0 | 0.011 | G | -72.0 | -33.0 | NA | NA | NA | |||||||||||||
| 4re1 | 1 | P28347 | 81.28 | 2e-137 |
X-RAY |
2014-11-19 | ILE | A:53 | A:244 | 1.0 | 0.006 | G | -68.4 | -25.3 | 1.0 | 0.006 | 0.0 |
HOH |
6.729 |
N |
O |
||
| ILE | B:53 | B:244 | 1.0 | 0.006 | G | -67.7 | -25.6 | NA | NA | NA | |||||||||||||
| 6hil | 1 | P28347 | 81.65 | 4e-137 |
X-RAY |
2019-04-03 | ILE | A:52 | A:244 | 0.0 | 0.0 | G | -65.3 | -20.3 | 0.0 | 0.0 | 0.0 |
HOH |
7.793 |
CD1 |
O |
||
| ILE | C:52 | D:244 | 0.0 | 0.0 | G | -55.7 | -37.5 | NA | NA | NA | |||||||||||||
| ILE | E:52 | B:244 | 0.0 | 0.0 | G | -54.9 | -27.0 | NA | NA | NA | |||||||||||||
| ILE | G:52 | C:244 | 0.0 | 0.0 | G | -54.9 | -26.8 | NA | NA | NA | |||||||||||||
| 3kys | 1 | P28347 | 81.65 | 4e-137 |
X-RAY |
2010-02-23 | ILE | A:52 | A:244 | 0.0 | 0.0 | G | -64.4 | -20.9 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | C:52 | C:244 | 0.0 | 0.0 | G | -63.4 | -19.6 | NA | NA | NA | |||||||||||||
| 6im5 | 1 | P28347 | 81.36 | 2e-136 |
X-RAY |
2019-02-06 | ILE | A:66 | A:259 | 0.0 | 0.0 | G | -64.4 | -19.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.450 |
O |
O |
||
| ILE | B:66 | B:259 | 0.0 | 0.0 | G | -61.8 | -22.2 | NA | NA | NA | |||||||||||||
| 7li5 | 1 | E9PKB7 | 81.94 | 6e-136 |
X-RAY |
2022-02-02 | ILE | A:55 | A:259 | 4.0 | 0.023 | G | -59.1 | -24.7 | 4.0 | 0.023 | 0.0 |
HOH |
3.640 |
CG2 |
O |
||
| ILE | B:55 | B:259 | 14.0 | 0.08 | H | -57.8 | -29.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q15561-f1 | 1 | Q15561 | 100.0 | 0.0 | ILE | A:267 | A:267 | 0.0 | 0.0 | G | -58.5 | -25.1 | |