Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3131088 . C A CCDS31729.1:NM_003213.3:c.802Cgc>Agc_NP_003204.2:p.268R>S Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 ARG A:53 A:268 146.0 0.649 G -60.5 -23.0 146.0 0.649 0.0 GOL
HOH
 9.521
2.765
 O
O
 O3
O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 ARG A:53 A:268 145.0 0.644 G -62.6 -23.8 145.0 0.644 0.0 HOH
 2.724
 O
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:53 A:268 147.0 0.653 G -59.6 -27.9 147.0 0.653 0.0 HOH
 2.703
 O
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:53 A:268 147.0 0.653 G -57.2 -29.8 147.0 0.653 0.0 HOH
 2.703
 O
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:53 A:268 143.0 0.636 G -62.1 -20.2 143.0 0.636 0.0 HOH
 3.243
 NH1
 O
ARG C:53 B:268 137.0 0.609 G -62.0 -20.5 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 ARG A:53 A:268 146.0 0.649 G -60.9 -26.8 146.0 0.649 0.0 HOH
 2.717
 O
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ARG A:53 A:268 141.0 0.627 G -61.4 -26.1 141.0 0.627 0.0 HOH
 2.653
 O
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ARG A:53 A:268 147.0 0.653 G -60.9 -27.5 147.0 0.653 0.0 HOH
 2.691
 O
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 ARG A:54 A:268 144.0 0.64 G -58.5 -26.2 144.0 0.64 0.0 GOL
HOH
 9.701
2.803
 O
O
 O3
O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 ARG A:54 A:268 161.0 0.716 G -57.9 -26.2 161.0 0.716 0.0 GOL
HOH
 9.565
2.694
 O
O
 O3
O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 ARG A:54 A:268 139.0 0.618 G -61.1 -25.6 136.0 0.604 0.014 C:None:0.013
 HOH
 2.707
 O
 O
ARG B:54 B:268 136.0 0.604 G -65.6 -19.8 135.0 0.6 0.004 D:None:0.004
 HOH
 4.567
 O
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ARG A:53 A:268 146.0 0.649 G -62.6 -26.1 146.0 0.649 0.0 HOH
 2.689
 O
 O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ARG A:53 A:268 145.0 0.644 G -62.8 -25.1 145.0 0.644 0.0 HOH
 2.736
 O
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 ARG A:54 A:268 165.0 0.733 G -66.1 -23.4 165.0 0.733 0.0 HOH
 4.264
 NH2
 O
ARG B:54 B:268 119.0 0.529 G -58.0 -26.8 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 ARG A:54 A:268 184.0 0.818 G -68.6 -1.2 184.0 0.818 0.0
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 ARG A:56 A:261 133.0 0.591 G -69.3 -16.2 133.0 0.591 0.0
ARG B:56 B:261 133.0 0.591 G -68.6 -21.1 133.0 0.591 0.0 GOL
 9.401
 C
 O2
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 ARG A:56 A:261 118.0 0.524 G -63.7 -24.8 118.0 0.524 0.0 HOH
 7.491
 N
 O
ARG C:56 B:261 133.0 0.591 G -59.4 -18.3 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 ARG A:55 A:261 137.0 0.609 G -56.8 -27.3 137.0 0.609 0.0 GOL
HOH
 7.393
1.718
 C
HH21
 H11
O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 ARG A:54 A:261 137.0 0.609 G -71.8 -20.7 137.0 0.609 0.0 HOH
 2.777
 NH2
 O
ARG C:54 C:261 136.0 0.604 G -52.3 -25.9 NA NA NA
ARG E:54 E:261 137.0 0.609 G -55.6 -30.1 NA NA NA
ARG G:54 G:261 138.0 0.613 G -72.6 -16.1 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 ARG A:54 A:261 141.0 0.627 G -59.8 -29.4 141.0 0.627 0.0
ARG B:54 B:261 124.0 0.551 G -61.5 -26.9 124.0 0.551 0.0 HOH
 7.069
 CB
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 ARG A:59 A:261 171.0 0.76 G -62.0 -28.7 171.0 0.76 0.0 HOH
 8.584
 CD
 O
ARG B:59 B:261 181.0 0.804 G -61.1 -28.1 NA NA NA
ARG C:59 C:261 164.0 0.729 G -68.1 -20.4 NA NA NA
ARG D:59 D:261 159.0 0.707 G -61.9 -28.4 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 ARG C:61 A:261 156.0 0.693 G -52.9 -32.7 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 ARG D:63 B:261 158.0 0.702 G -56.3 -7.8 158.0 0.702 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 ARG A:64 A:260 47.0 NA G -64.0 -21.8 47.0 NA NA
ARG B:64 B:260 139.0 0.618 G -54.6 -23.6 NA NA NA
ARG C:64 C:260 68.0 NA G -64.6 -21.9 NA NA NA
ARG D:64 D:260 184.0 0.818 G -54.5 -24.9 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 ARG A:54 A:245 146.0 0.649 G -58.5 -26.6 146.0 0.649 0.0 HOH
 4.390
 NH2
 O
ARG B:54 B:245 149.0 0.662 G -56.1 -27.2 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 ARG A:53 A:245 132.0 0.587 G -70.8 -33.6 132.0 0.587 0.0
ARG C:53 D:245 153.0 0.68 G -55.0 -20.5 NA NA NA
ARG E:53 B:245 143.0 0.636 G -63.9 -22.7 NA NA NA
ARG G:53 C:245 153.0 0.68 G -66.1 -27.0 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 ARG A:53 A:245 145.0 0.644 G -68.5 -25.6 145.0 0.644 0.0
ARG C:53 C:245 144.0 0.64 G -69.2 -24.7 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 ARG A:67 A:260 148.0 0.658 G -65.0 -22.4 148.0 0.658 0.0 HOH
 2.826
 O
 O
ARG B:67 B:260 133.0 0.591 G -64.5 -20.5 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 ARG A:56 A:260 180.0 0.8 G -60.1 -24.7 180.0 0.8 0.0 HOH
 2.691
 NH1
 O
ARG B:56 B:260 216.0 0.96 H -59.0 -27.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 ARG A:268 A:268 127.0 0.564 G -61.1 -25.4