Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3131121 . G A CCDS31729.1:NM_003213.3:c.835Ggt>Agt_NP_003204.2:p.279G>S Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLY A:64 A:279 33.0 0.44 T 83.7 -7.7 33.0 0.44 0.0 HOH
 2.663
 O
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLY A:64 A:279 31.0 0.413 T 87.6 -9.6 31.0 0.413 0.0 HOH
 2.673
 O
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLY A:64 A:279 32.0 0.427 T 80.9 -0.5 32.0 0.427 0.0 HOH
 2.733
 O
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLY A:64 A:279 32.0 0.427 T 79.3 -3.9 32.0 0.427 0.0 HOH
 2.660
 O
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLY A:64 A:279 37.0 0.493 T 70.9 12.0 37.0 0.493 0.0 HOH
 4.544
 O
 O
GLY C:64 B:279 37.0 0.493 T 81.8 17.7 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 GLY A:64 A:279 28.0 0.373 T 85.1 -5.3 28.0 0.373 0.0 HOH
 2.616
 O
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 GLY A:64 A:279 30.0 0.4 T 79.5 -4.5 30.0 0.4 0.0 HOH
 2.636
 O
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 GLY A:64 A:279 33.0 0.44 T 86.1 -7.9 33.0 0.44 0.0 HOH
 2.668
 O
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 GLY A:65 A:279 32.0 0.427 T 79.2 -3.0 32.0 0.427 0.0 HOH
 2.594
 O
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLY A:65 A:279 33.0 0.44 T 77.3 0.0 33.0 0.44 0.0 HOH
 2.606
 O
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLY A:65 A:279 34.0 0.453 T 89.3 9.0 34.0 0.453 0.0 HOH
 2.611
 O
 O
GLY B:65 B:279 37.0 0.493 T 82.2 4.3 37.0 0.493 0.0 HOH
 2.901
 O
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 GLY A:64 A:279 32.0 0.427 T 88.1 -5.4 32.0 0.427 0.0 HOH
 2.660
 O
 O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 GLY A:64 A:279 34.0 0.453 T 88.9 -10.8 34.0 0.453 0.0 HOH
 2.689
 O
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLY A:65 A:279 27.0 0.36 T 82.3 1.5 27.0 0.36 0.0 HOH
 5.163
 O
 O
GLY B:65 B:279 36.0 0.48 T 85.3 0.5 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLY A:65 A:279 39.0 0.52 T 107.6 -10.1 39.0 0.52 0.0 HOH
 7.886
 O
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 GLY A:67 A:272 48.0 0.64 T -57.4 2.0 48.0 0.64 0.0 HOH
 6.715
 O
 O
GLY B:67 B:272 34.0 0.453 T 84.9 0.2 34.0 0.453 0.0
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 GLY A:67 A:272 44.0 0.587 S -75.2 51.7 44.0 0.587 0.0 HOH
 3.617
 O
 O
GLY C:67 B:272 43.0 0.573 S -79.6 47.2 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 GLY A:66 A:272 30.0 0.4 T 79.1 1.4 30.0 0.4 0.0 HOH
 2.667
 O
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 GLY A:65 A:272 60.0 0.8 S -77.9 86.0 60.0 0.8 0.0 HOH
 5.150
 O
 O
GLY C:65 C:272 28.0 0.373 S -121.3 103.6 NA NA NA
GLY E:65 E:272 44.0 0.587 S -112.1 42.3 NA NA NA
GLY G:65 G:272 89.0 1.0 360.0 -9.7 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 GLY A:65 A:272 35.0 0.467 T 70.5 8.1 35.0 0.467 0.0 HOH
 6.198
 O
 O
GLY B:65 B:272 29.0 0.387 T 69.4 7.8 29.0 0.387 0.0 HOH
 4.792
 C
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 GLY A:70 A:272 41.0 0.547 T 84.1 0.9 41.0 0.547 0.0 HOH
 8.674
 CA
 O
GLY B:70 B:272 43.0 0.573 T 87.2 -1.9 NA NA NA
GLY C:70 C:272 43.0 0.573 T 87.1 2.9 NA NA NA
GLY D:70 D:272 54.0 0.72 T 89.4 4.1 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 GLY C:72 A:272 56.0 0.747 T -77.8 42.8 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 GLY D:74 B:272 60.0 0.8 T -84.0 22.1 60.0 0.8 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 GLY A:75 A:271 20.0 0.267 T 81.2 10.3 20.0 0.267 0.0
GLY B:75 B:271 25.0 0.333 T 78.1 20.3 NA NA NA
GLY C:75 C:271 35.0 0.467 T 81.7 11.2 NA NA NA
GLY D:75 D:271 27.0 0.36 T 77.8 21.1 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 GLY A:65 A:256 27.0 0.36 T 92.6 10.4 27.0 0.36 0.0 HOH
 4.859
 C
 O
GLY B:65 B:256 24.0 0.32 T 92.5 10.1 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 GLY A:64 A:256 21.0 0.28 T 91.7 20.7 21.0 0.28 0.0 HOH
 7.374
 O
 O
GLY C:64 D:256 24.0 0.32 T 77.4 15.8 NA NA NA
GLY E:64 B:256 21.0 0.28 T 79.0 11.9 NA NA NA
GLY G:64 C:256 20.0 0.267 T 94.3 5.6 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 GLY A:64 A:256 25.0 0.333 T 70.7 37.3 25.0 0.333 0.0 HOH
 6.172
 CA
 O
GLY C:64 C:256 32.0 0.427 S 77.4 42.2 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 GLY A:78 A:271 29.0 0.387 T 75.6 9.4 29.0 0.387 0.0 HOH
 2.688
 O
 O
GLY B:78 B:271 30.0 0.4 T 69.9 8.2 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 GLY A:67 A:271 37.0 0.493 T 72.7 11.0 37.0 0.493 0.0 HOH
 2.624
 O
 O
GLY B:67 B:271 29.0 0.387 T 73.2 10.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 GLY A:279 A:279 26.0 0.347 T 77.7 10.4