Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 3131157 | . | A | C | CCDS31729.1:NM_003213.3:c.871Aat>Cat_NP_003204.2:p.291N>H | Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6ge3 | 1 | Q15561 | 100.0 | 3e-166 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 81.0 | 0.506 | G | -76.7 | 7.0 | 81.0 | 0.506 | 0.0 |
HOH |
2.715 |
OD1 |
O |
||
| 6gec | 1 | Q15561 | 100.0 | 3e-166 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 57.0 | 0.356 | G | -83.1 | 7.4 | 57.0 | 0.356 | 0.0 |
HOH |
2.860 |
OD1 |
O |
||
| 6ge5 | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 77.0 | 0.481 | G | -78.8 | 1.2 | 77.0 | 0.481 | 0.0 |
HOH |
2.923 |
OD1 |
O |
||
| 6geg | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 80.0 | 0.5 | G | -79.7 | 2.5 | 80.0 | 0.5 | 0.0 |
HOH |
3.027 |
OD1 |
O |
||
| 6gek | 1 | Q15561 | 99.54 | 1e-165 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 60.0 | 0.375 | G | -87.9 | 10.5 | 60.0 | 0.375 | 0.0 |
HOH |
2.727 |
OD1 |
O |
||
| ASN | C:76 | B:291 | 69.0 | 0.431 | G | -73.8 | -0.7 | NA | NA | NA | |||||||||||||
| 6hik | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2019-04-03 | ASN | A:76 | A:291 | 57.0 | 0.356 | G | -74.7 | 1.7 | 57.0 | 0.356 | 0.0 |
HOH |
2.737 |
OD1 |
O |
||
| 6ge4 | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 77.0 | 0.481 | G | -77.2 | 5.3 | 77.0 | 0.481 | 0.0 |
HOH |
2.913 |
N |
O |
||
| 6gee | 1 | Q15561 | 99.54 | 2e-165 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 57.0 | 0.356 | G | -80.7 | 3.4 | 57.0 | 0.356 | 0.0 |
HOH |
2.914 |
OD1 |
O |
||
| 5oaq | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2017-10-11 | ASN | A:77 | A:291 | 81.0 | 0.506 | G | -81.2 | 3.8 | 81.0 | 0.506 | 0.0 |
HOH |
2.708 |
OD1 |
O |
||
| 6q2x | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2019-07-03 | ASN | A:77 | A:291 | 81.0 | 0.506 | G | -78.8 | 6.0 | 81.0 | 0.506 | 0.0 |
HOH |
2.922 |
OD1 |
O |
||
| 6q36 | 1 | Q15561 | 100.0 | 5e-165 |
X-RAY |
2019-07-03 | ASN | A:77 | A:291 | 85.0 | 0.531 | G | -72.4 | -3.1 | 85.0 | 0.531 | 0.0 |
HOH |
3.195 |
O |
O |
||
| ASN | B:77 | B:291 | 62.0 | 0.388 | G | -76.0 | -1.9 | 62.0 | 0.388 | 0.0 |
HOH |
2.723 |
OD1 |
O |
|||||||||
| 6ge6 | 1 | Q15561 | 99.09 | 1e-164 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 79.0 | 0.494 | G | -76.6 | 3.9 | 79.0 | 0.494 | 0.0 |
HOH |
2.926 |
OD1 |
O |
||
| 6gei | 1 | Q15561 | 99.09 | 1e-164 |
X-RAY |
2018-09-19 | ASN | A:76 | A:291 | 77.0 | 0.481 | G | -78.2 | 4.9 | 77.0 | 0.481 | 0.0 |
HOH |
2.868 |
OD1 |
O |
||
| 6sen | 1 | Q15561 | 99.54 | 5e-164 |
X-RAY |
2019-11-20 | ASN | A:77 | A:291 | 77.0 | 0.481 | G | -73.0 | 2.8 | 77.0 | 0.481 | 0.0 |
HOH |
2.916 |
ND2 |
O |
||
| ASN | B:77 | B:291 | 77.0 | 0.481 | G | -69.2 | -0.7 | NA | NA | NA | |||||||||||||
| 6seo | 1 | Q15561 | 99.54 | 5e-164 |
X-RAY |
2019-11-20 | ASN | A:77 | A:291 | 82.0 | 0.512 | G | -75.5 | -7.8 | 82.0 | 0.512 | 0.0 |
HOH |
3.238 |
O |
O |
||
| 4ln0 | 1 | Q62296 | 96.35 | 3e-161 |
X-RAY |
2014-02-26 | ASN | A:79 | A:284 | 59.0 | 0.369 | G | -91.6 | 9.2 | 59.0 | 0.369 | 0.0 | ||||||
| ASN | B:79 | B:284 | 56.0 | 0.35 | G | -90.5 | 9.1 | 56.0 | 0.35 | 0.0 | |||||||||||||
| 6l9f | 1 | Q62296 | 96.35 | 3e-161 |
X-RAY |
2019-12-11 | ASN | A:79 | A:284 | 66.0 | 0.412 | G | -71.4 | 16.4 | 66.0 | 0.412 | 0.0 |
HOH |
3.266 |
OD1 |
O |
||
| ASN | C:79 | B:284 | 58.0 | 0.362 | G | -72.1 | 8.2 | NA | NA | NA | |||||||||||||
| 6sba | 1 | Q62296 | 96.35 | 9e-161 |
X-RAY |
2020-09-30 | ASN | A:78 | A:284 | 48.0 | 0.3 | G | -77.7 | 4.6 | 48.0 | 0.3 | 0.0 |
HOH |
2.292 |
H |
O |
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| 3jua | 1 | Q62296 | 96.33 | 2e-160 |
X-RAY |
2010-02-23 | ASN | A:77 | A:284 | 54.0 | 0.338 | T | -99.5 | 13.1 | 54.0 | 0.338 | 0.0 |
HOH |
2.684 |
OD1 |
O |
||
| ASN | C:77 | C:284 | 63.0 | 0.394 | G | -70.2 | 10.3 | NA | NA | NA | |||||||||||||
| ASN | E:77 | E:284 | 32.0 | 0.2 | G | -73.5 | 7.8 | NA | NA | NA | |||||||||||||
| ASN | G:77 | G:284 | 49.0 | 0.306 | G | -69.9 | 2.6 | NA | NA | NA | |||||||||||||
| 5xjd | 1 | Q62296 | 96.33 | 2e-160 |
X-RAY |
2018-01-24 | ASN | A:77 | A:284 | 52.0 | 0.325 | G | -74.0 | -0.4 | 52.0 | 0.325 | 0.0 |
HOH |
3.137 |
OD1 |
O |
||
| ASN | B:77 | B:284 | 55.0 | 0.344 | G | -74.0 | -0.3 | 55.0 | 0.344 | 0.0 |
HOH |
3.274 |
C |
O |
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| 5gn0 | 1 | Q62296 | 96.33 | 4e-160 |
X-RAY |
2017-05-31 | ASN | A:82 | A:284 | 47.0 | 0.294 | G | -69.6 | -7.5 | 47.0 | 0.294 | 0.0 | ||||||
| ASN | B:82 | B:284 | 55.0 | 0.344 | G | -84.4 | 3.0 | NA | NA | NA | |||||||||||||
| ASN | C:82 | C:284 | 61.0 | 0.381 | G | -85.0 | -2.7 | NA | NA | NA | |||||||||||||
| ASN | D:82 | D:284 | 49.0 | 0.306 | G | -91.2 | 5.3 | NA | NA | NA | |||||||||||||
| 5z2q | 3 | Q62296 | 96.31 | 1e-159 |
X-RAY |
2018-01-31 | ASN | C:84 | A:284 | 22.0 | 0.138 | G | -74.3 | -7.3 | NA | NA | NA | ||||||
| 5z2q | 4 | Q62296 | 96.31 | 2e-159 |
X-RAY |
2018-01-31 | ASN | D:86 | B:284 | 25.0 | 0.156 | G | -76.9 | -5.7 | 25.0 | 0.156 | 0.0 | ||||||
| 7cmm | 1 | P28347 | 81.45 | 8e-139 |
X-RAY |
2021-02-03 | ASN | A:87 | A:283 | 81.0 | 0.506 | G | -72.6 | -21.3 | 81.0 | 0.506 | 0.0 | ||||||
| ASN | B:87 | B:283 | 78.0 | 0.487 | G | -72.4 | -16.6 | NA | NA | NA | |||||||||||||
| ASN | C:87 | C:283 | 77.0 | 0.481 | G | -71.9 | -19.9 | NA | NA | NA | |||||||||||||
| ASN | D:87 | D:283 | 76.0 | 0.475 | G | -73.2 | -15.4 | NA | NA | NA | |||||||||||||
| 4re1 | 1 | P28347 | 81.28 | 2e-137 |
X-RAY |
2014-11-19 | ASN | A:77 | A:268 | 112.0 | 0.7 | G | -74.4 | -5.9 | 112.0 | 0.7 | 0.0 |
HOH |
2.784 |
OD1 |
O |
||
| ASN | B:77 | B:268 | 107.0 | 0.669 | G | -72.0 | -10.9 | NA | NA | NA | |||||||||||||
| 6hil | 1 | P28347 | 81.65 | 4e-137 |
X-RAY |
2019-04-03 | ASN | A:76 | A:268 | 73.0 | 0.456 | G | -82.1 | -11.3 | 73.0 | 0.456 | 0.0 |
HOH |
5.523 |
N |
O |
||
| ASN | C:76 | D:268 | 85.0 | 0.531 | G | -83.4 | 1.6 | NA | NA | NA | |||||||||||||
| ASN | E:76 | B:268 | 101.0 | 0.631 | G | -83.8 | -7.2 | NA | NA | NA | |||||||||||||
| ASN | G:76 | C:268 | 82.0 | 0.512 | G | -74.2 | -10.4 | NA | NA | NA | |||||||||||||
| 3kys | 1 | P28347 | 81.65 | 4e-137 |
X-RAY |
2010-02-23 | ASN | A:76 | A:268 | 80.0 | 0.5 | G | -81.4 | 2.7 | 80.0 | 0.5 | 0.0 |
HOH |
9.263 |
N |
O |
||
| ASN | C:76 | C:268 | 84.0 | 0.525 | G | -85.2 | 2.1 | NA | NA | NA | |||||||||||||
| 6im5 | 1 | P28347 | 81.36 | 2e-136 |
X-RAY |
2019-02-06 | ASN | A:90 | A:283 | 76.0 | 0.475 | G | -78.1 | 2.3 | 76.0 | 0.475 | 0.0 |
HOH |
2.538 |
OD1 |
O |
||
| ASN | B:90 | B:283 | 78.0 | 0.487 | G | -79.1 | 3.8 | NA | NA | NA | |||||||||||||
| 7li5 | 1 | E9PKB7 | 81.94 | 6e-136 |
X-RAY |
2022-02-02 | ASN | A:79 | A:283 | 72.0 | 0.45 | G | -75.3 | -0.1 | 72.0 | 0.45 | 0.0 |
HOH |
2.778 |
OD1 |
O |
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| ASN | B:79 | B:283 | 66.0 | 0.412 | G | -74.7 | -1.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q15561-f1 | 1 | Q15561 | 100.0 | 0.0 | ASN | A:291 | A:291 | 46.0 | 0.287 | G | -73.7 | -4.8 | |