Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3147206 . G A CCDS31729.1:NM_003213.3:c.970Gag>Aag_NP_003204.2:p.324E>K Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLU A:109 A:324 88.0 0.463 S -106.7 151.2 88.0 0.463 0.0 HOH
 2.771
 OE1
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLU A:109 A:324 81.0 0.426 S -108.7 144.9 81.0 0.426 0.0 HOH
 2.656
 OE1
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLU A:109 A:324 88.0 0.463 S -103.6 143.8 88.0 0.463 0.0 HOH
 2.695
 OE1
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLU A:109 A:324 88.0 0.463 S -111.8 140.9 88.0 0.463 0.0 HOH
 2.605
 OE1
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLU A:109 A:324 67.0 0.353 S -102.0 151.0 67.0 0.353 0.0 HOH
 3.155
 CG
 O
GLU C:109 B:324 80.0 0.421 S -106.2 142.7 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 GLU A:109 A:324 81.0 0.426 S -101.3 145.6 81.0 0.426 0.0 HOH
 3.556
 CA
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 GLU A:109 A:324 83.0 0.437 S -105.5 146.8 83.0 0.437 0.0 HOH
 3.585
 CA
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 GLU A:109 A:324 87.0 0.458 S -104.8 141.9 87.0 0.458 0.0 HOH
 2.700
 OE1
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 GLU A:110 A:324 83.0 0.437 S -108.0 151.3 83.0 0.437 0.0 HOH
 3.477
 CA
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLU A:110 A:324 91.0 0.479 S -107.0 147.3 91.0 0.479 0.0 HOH
 3.474
 CA
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLU A:110 A:324 79.0 0.416 S -109.5 156.7 79.0 0.416 0.0 HOH
 2.927
 OE2
 O
GLU B:110 B:324 72.0 0.379 S -107.1 144.9 72.0 0.379 0.0 HOH
 2.792
 OE2
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 GLU A:109 A:324 84.0 0.442 S -105.4 145.8 84.0 0.442 0.0 HOH
 2.555
 OE1
 O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 GLU A:109 A:324 78.0 0.411 S -106.5 144.2 78.0 0.411 0.0 HOH
 2.662
 OE1
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLU A:110 A:324 79.0 0.416 S -110.1 153.8 79.0 0.416 0.0 HOH
 2.776
 OE2
 O
GLU B:110 B:324 78.0 0.411 S -104.0 150.0 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLU A:110 A:324 77.0 0.405 S -118.7 145.8 77.0 0.405 0.0 HOH
 3.162
 OE1
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 GLU A:112 A:317 89.0 0.468 S -90.0 158.2 89.0 0.468 0.0
GLU B:112 B:317 43.0 NA S -89.5 154.3 43.0 NA NA
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 GLU A:112 A:317 85.0 0.447 S -109.4 146.7 85.0 0.447 0.0 HOH
 5.245
 OE1
 O
GLU C:112 B:317 80.0 0.421 S -108.5 145.1 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 GLU A:111 A:317 81.0 0.426 S -112.3 150.0 81.0 0.426 0.0 HOH
 2.621
 OE1
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 GLU A:110 A:317 105.0 0.553 S -119.2 161.7 105.0 0.553 0.0 HOH
 3.047
 CD
 O
GLU C:110 C:317 93.0 0.489 S -126.4 139.8 NA NA NA
GLU E:110 E:317 94.0 0.495 S -109.2 149.5 NA NA NA
GLU G:110 G:317 130.0 0.684 S -114.0 148.3 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 GLU A:110 A:317 105.0 0.553 S -126.6 153.4 105.0 0.553 0.0 HOH
 4.780
 N
 O
GLU B:110 B:317 86.0 0.453 S -135.0 160.7 86.0 0.453 0.0 HOH
 2.592
 OE2
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 GLU A:115 A:317 95.0 0.5 S -103.7 152.3 95.0 0.5 0.0
GLU B:115 B:317 96.0 0.505 S -104.0 168.3 NA NA NA
GLU C:115 C:317 109.0 0.574 S -120.2 158.6 NA NA NA
GLU D:115 D:317 106.0 0.558 S -95.6 154.8 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 GLU C:117 A:317 86.0 0.453 S -90.2 152.7 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 GLU D:119 B:317 105.0 0.553 S -90.8 152.0 105.0 0.553 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 GLU A:120 A:316 91.0 0.479 S -94.8 158.2 91.0 0.479 0.0
GLU B:120 B:316 81.0 0.426 S -117.9 154.6 NA NA NA
GLU C:120 C:316 118.0 0.621 S -97.8 161.9 NA NA NA
GLU D:120 D:316 92.0 0.484 S -115.0 155.2 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 GLU A:110 A:301 36.0 NA S -110.5 145.9 36.0 NA NA HOH
 9.712
 CB
 O
GLU B:110 B:301 102.0 0.537 S -105.9 147.5 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 GLU A:109 A:301 132.0 0.695 S -121.8 140.3 132.0 0.695 0.0 HOH
 5.644
 C
 O
GLU C:109 D:301 119.0 0.626 S -110.7 131.0 NA NA NA
GLU E:109 B:301 117.0 0.616 S -120.3 139.1 NA NA NA
GLU G:109 C:301 107.0 0.563 S -103.7 137.8 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 GLU A:109 A:301 110.0 0.579 S -127.5 154.0 110.0 0.579 0.0
GLU C:109 C:301 97.0 0.511 S -122.5 147.3 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 GLU A:123 A:316 40.0 NA S -107.8 145.4 40.0 NA NA HOH
 3.479
 CA
 O
GLU B:123 B:316 123.0 0.647 S -106.0 147.4 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 GLU A:112 A:316 95.0 0.5 S -104.5 142.7 95.0 0.5 0.0 HOH
 3.684
 CA
 O
GLU B:112 B:316 122.0 0.642 S -116.2 150.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 GLU A:324 A:324 89.0 0.468 S -109.6 141.8