Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3147222 . C A CCDS31729.1:NM_003213.3:c.986aCc>aAc_NP_003204.2:p.329T>N Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 THR A:114 A:329 21.0 0.15 E -117.8 134.1 21.0 0.15 0.0 HOH
 3.081
 O
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 THR A:114 A:329 26.0 0.186 E -117.6 133.2 26.0 0.186 0.0 HOH
 3.182
 O
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 THR A:114 A:329 22.0 0.157 E -117.8 129.3 22.0 0.157 0.0 HOH
 2.909
 O
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 THR A:114 A:329 23.0 0.164 E -115.2 133.6 23.0 0.164 0.0 HOH
 3.164
 O
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 THR A:114 A:329 25.0 0.179 E -110.4 128.0 25.0 0.179 0.0 HOH
 3.687
 O
 O
THR C:114 B:329 28.0 0.2 E -110.6 125.8 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 THR A:114 A:329 22.0 0.157 E -120.1 135.9 22.0 0.157 0.0 HOH
 6.592
 C
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 THR A:114 A:329 25.0 0.179 E -115.4 128.8 25.0 0.179 0.0 HOH
 3.116
 O
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 THR A:114 A:329 27.0 0.193 E -117.0 131.0 27.0 0.193 0.0 HOH
 3.002
 O
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 THR A:115 A:329 23.0 0.164 E -117.7 135.0 23.0 0.164 0.0 HOH
 3.081
 O
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 THR A:115 A:329 23.0 0.164 E -116.4 129.5 23.0 0.164 0.0 HOH
 2.841
 O
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 THR A:115 A:329 26.0 0.186 E -119.9 125.7 26.0 0.186 0.0 HOH
 2.964
 OG1
 O
THR B:115 B:329 25.0 0.179 E -119.8 128.6 25.0 0.179 0.0 HOH
 3.193
 O
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 THR A:114 A:329 23.0 0.164 E -116.0 130.9 23.0 0.164 0.0 HOH
 3.174
 O
 O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 THR A:114 A:329 25.0 0.179 E -116.6 131.6 25.0 0.179 0.0 HOH
 3.085
 O
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 THR A:115 A:329 24.0 0.171 E -128.1 122.5 24.0 0.171 0.0 HOH
 3.056
 O
 O
THR B:115 B:329 29.0 0.207 E -117.7 126.5 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 THR A:115 A:329 27.0 0.193 E -131.1 121.7 27.0 0.193 0.0 HOH
 9.723
 CG2
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 THR A:117 A:322 23.0 0.164 E -105.9 121.3 23.0 0.164 0.0 HOH
 8.536
 O
 O
THR B:117 B:322 20.0 0.143 E -107.2 123.7 12.0 0.086 0.057 C:Q80V24:0.057
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 THR A:117 A:322 26.0 0.186 E -126.2 135.7 26.0 0.186 0.0 HOH
 3.582
 OG1
 O
THR C:117 B:322 27.0 0.193 E -107.5 132.7 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 THR A:116 A:322 13.0 0.093 E -128.3 128.9 13.0 0.093 0.0 HOH
 3.315
 O
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 THR A:115 A:322 34.0 0.243 E -94.2 128.1 34.0 0.243 0.0 HOH
 3.185
 O
 O
THR C:115 C:322 30.0 0.214 E -111.2 115.5 NA NA NA
THR E:115 E:322 27.0 0.193 E -116.2 114.8 NA NA NA
THR G:115 G:322 29.0 0.207 E -118.8 126.2 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 THR A:115 A:322 28.0 0.2 E -110.2 125.2 28.0 0.2 0.0 HOH
 3.022
 OG1
 O
THR B:115 B:322 29.0 0.207 E -111.8 125.1 29.0 0.207 0.0 HOH
 2.900
 OG1
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 THR A:120 A:322 30.0 0.214 E -107.0 123.4 30.0 0.214 0.0 HOH
 9.774
 CG2
 O
THR B:120 B:322 31.0 0.221 E -117.6 134.8 NA NA NA
THR C:120 C:322 37.0 0.264 E -122.0 140.6 NA NA NA
THR D:120 D:322 29.0 0.207 E -111.6 130.6 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 THR C:122 A:322 21.0 0.15 E -114.8 146.6 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 THR D:124 B:322 23.0 0.164 E -113.7 145.3 23.0 0.164 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 THR A:125 A:321 25.0 0.179 E -116.9 122.4 25.0 0.179 0.0 HOH
 9.087
 C
 O
THR B:125 B:321 13.0 0.093 E -120.6 124.3 NA NA NA
THR C:125 C:321 15.0 0.107 E -119.6 122.0 NA NA NA
THR D:125 D:321 13.0 0.093 E -122.3 123.1 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 THR A:115 A:306 27.0 0.193 E -110.6 121.0 27.0 0.193 0.0 HOH
 3.204
 O
 O
THR B:115 B:306 22.0 0.157 E -111.9 124.6 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 THR A:114 A:306 23.0 0.164 E -115.9 131.1 23.0 0.164 0.0 HOH
 6.974
 C
 O
THR C:114 D:306 29.0 0.207 E -119.2 131.8 NA NA NA
THR E:114 B:306 23.0 0.164 E -118.3 115.7 NA NA NA
THR G:114 C:306 24.0 0.171 E -108.8 133.9 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 THR A:114 A:306 22.0 0.157 E -115.7 124.4 22.0 0.157 0.0 HOH
 7.918
 CG2
 O
THR C:114 C:306 22.0 0.157 E -108.8 124.0 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 THR A:128 A:321 27.0 0.193 E -112.4 128.1 27.0 0.193 0.0 HOH
 2.472
 OG1
 O
THR B:128 B:321 24.0 0.171 E -116.6 126.2 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 THR A:117 A:321 25.0 0.179 E -109.8 126.2 25.0 0.179 0.0 HOH
 3.198
 O
 O
THR B:117 B:321 22.0 0.157 E -117.2 125.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 THR A:329 A:329 22.0 0.157 E -115.7 120.3