Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3147225 . G A CCDS31729.1:NM_003213.3:c.989tGc>tAc_NP_003204.2:p.330C>Y Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 CYS A:115 A:330 2.0 0.015 E -112.8 116.0 2.0 0.015 0.0 MYR
HOH
 8.564
2.905
 SG
O
 C3
O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 CYS A:115 A:330 2.0 0.015 E -113.5 114.5 2.0 0.015 0.0 MYR
HOH
 8.434
2.866
 SG
O
 C5
O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 CYS A:115 A:330 2.0 0.015 E -105.4 114.0 2.0 0.015 0.0 MYR
HOH
 8.477
3.017
 SG
O
 C5
O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 CYS A:115 A:330 3.0 0.022 E -111.4 116.9 3.0 0.022 0.0 MYR
HOH
 8.464
2.961
 SG
O
 C5
O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 CYS A:115 A:330 2.0 0.015 E -109.7 116.8 2.0 0.015 0.0 MYR
HOH
 8.579
2.700
 SG
O
 C5
O
CYS C:115 B:330 1.0 0.007 E -107.1 115.9 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 CYS A:115 A:330 2.0 0.015 E -114.7 114.6 2.0 0.015 0.0 MYR
HOH
 8.445
2.895
 SG
O
 C5
O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 CYS A:115 A:330 3.0 0.022 E -108.7 120.9 3.0 0.022 0.0 MYR
HOH
 8.427
2.717
 SG
SG
 C5
O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 CYS A:115 A:330 2.0 0.015 E -112.0 110.6 2.0 0.015 0.0 MYR
HOH
 8.290
2.725
 SG
O
 C5
O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 CYS A:116 A:330 2.0 0.015 E -114.7 118.0 2.0 0.015 0.0 MYR
HOH
 8.655
2.946
 SG
O
 C5
O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 CYS A:116 A:330 2.0 0.015 E -110.0 117.0 2.0 0.015 0.0 MYR
HOH
 8.434
3.027
 SG
O
 C5
O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 CYS A:116 A:330 2.0 0.015 E -108.0 118.4 2.0 0.015 0.0 HOH
 3.034
 O
 O
CYS B:116 B:330 3.0 0.022 E -111.9 117.2 3.0 0.022 0.0 HOH
 2.912
 O
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 CYS A:115 A:330 2.0 0.015 E -110.6 112.8 2.0 0.015 0.0 MYR
HOH
 8.322
2.747
 SG
O
 C5
O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 CYS A:115 A:330 3.0 0.022 E -110.9 113.8 3.0 0.022 0.0 MYR
HOH
 8.129
2.810
 SG
O
 C3
O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 CYS A:116 A:330 6.0 0.044 E -101.7 121.8 6.0 0.044 0.0 HOH
 4.480
 SG
 O
CYS B:116 B:330 1.0 0.007 E -110.1 119.2 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 CYS A:116 A:330 5.0 0.037 E -110.2 110.9 5.0 0.037 0.0 HOH
 7.405
 O
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 CYS A:118 A:323 10.0 0.074 E -101.9 118.3 10.0 0.074 0.0 PEG
HOH
 8.500
6.959
 SG
C
 C1
O
CYS B:118 B:323 7.0 0.052 E -100.3 118.3 7.0 0.052 0.0 PEG
 8.707
 SG
 C4
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 CYS A:118 A:323 15.0 0.111 E -118.7 114.7 15.0 0.111 0.0 HOH
 2.911
 O
 O
CYS C:118 B:323 5.0 0.037 E -116.3 114.0 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 CYS A:117 A:323 3.0 0.022 E -108.3 117.4 3.0 0.022 0.0 HOH
 2.467
 HG
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 CYS A:116 A:323 5.0 0.037 E -119.0 116.0 5.0 0.037 0.0 HOH
 4.121
 SG
 O
CYS C:116 C:323 3.0 0.022 E -89.7 134.8 NA NA NA
CYS E:116 E:323 2.0 0.015 E -99.6 122.8 NA NA NA
CYS G:116 G:323 4.0 0.03 E -112.0 115.5 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 CYS A:116 A:323 12.0 0.089 E -110.6 113.6 12.0 0.089 0.0 HOH
 2.769
 O
 O
CYS B:116 B:323 22.0 0.163 E -111.6 114.8 22.0 0.163 0.0 HOH
 4.589
 N
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 CYS A:121 A:323 7.0 0.052 E -110.6 117.9 7.0 0.052 0.0
CYS B:121 B:323 10.0 0.074 E -115.6 121.8 NA NA NA
CYS C:121 C:323 9.0 0.067 E -119.1 128.2 NA NA NA
CYS D:121 D:323 9.0 0.067 E -112.8 121.5 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 CYS C:123 A:323 11.0 0.081 E -118.9 125.1 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 CYS D:125 B:323 8.0 0.059 E -121.3 121.9 8.0 0.059 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 CYS A:126 A:322 3.0 0.022 E -106.1 109.0 3.0 0.022 0.0 KK9
HOH
 9.053
5.656
 O
CB
 O2
O
CYS B:126 B:322 5.0 0.037 E -109.7 109.3 NA NA NA
CYS C:126 C:322 2.0 0.015 E -106.2 111.1 NA NA NA
CYS D:126 D:322 3.0 0.022 E -111.3 107.5 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 CYS A:116 A:307 1.0 0.007 E -111.2 114.5 1.0 0.007 0.0 HOH
 4.416
 C
 O
CYS B:116 B:307 2.0 0.015 E -108.4 112.8 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 CYS A:115 A:307 7.0 0.052 E -115.8 124.8 7.0 0.052 0.0 HOH
 6.216
 C
 O
CYS C:115 D:307 5.0 0.037 E -116.9 110.2 NA NA NA
CYS E:115 B:307 4.0 0.03 E -93.4 123.2 NA NA NA
CYS G:115 C:307 3.0 0.022 E -116.0 114.1 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 CYS A:115 A:307 1.0 0.007 E -106.6 122.7 1.0 0.007 0.0 HOH
 9.345
 C
 O
CYS C:115 C:307 0.0 0.0 E -110.3 114.4 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 CYS A:129 A:322 2.0 0.015 E -105.2 118.1 2.0 0.015 0.0 HOH
 2.968
 O
 O
CYS B:129 B:322 2.0 0.015 E -104.8 117.6 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 CYS A:118 A:322 5.0 0.037 E -106.6 120.6 5.0 0.037 0.0 Y2D
HOH
 7.014
3.027
 CB
O
 N5
O
CYS B:118 B:322 6.0 0.044 E -103.7 122.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 CYS A:330 A:330 2.0 0.015 E -100.7 108.6