Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3149285 . C A CCDS31729.1:NM_003213.3:c.1051Cgc>Agc_NP_003204.2:p.351R>S Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 ARG A:136 A:351 188.0 0.836 E -121.3 130.8 188.0 0.836 0.0 HOH
 2.603
 NH1
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 ARG A:136 A:351 191.0 0.849 E -123.1 132.6 191.0 0.849 0.0 HOH
 2.753
 NH1
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:136 A:351 186.0 0.827 E -126.4 128.5 186.0 0.827 0.0 HOH
 2.762
 NH1
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:136 A:351 185.0 0.822 E -123.0 131.8 185.0 0.822 0.0 HOH
 2.700
 NH1
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:136 A:351 180.0 0.8 E -132.8 129.2 180.0 0.8 0.0 HOH
 4.789
 N
 O
ARG C:136 B:351 179.0 0.796 E -127.4 124.1 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 ARG A:136 A:351 184.0 0.818 E -122.4 132.4 184.0 0.818 0.0 PO4
HOH
 2.795
3.743
 NH1
CD
 O3
O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ARG A:136 A:351 177.0 0.787 E -124.1 129.2 177.0 0.787 0.0 HOH
 2.679
 NH1
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ARG A:136 A:351 180.0 0.8 E -122.7 128.7 180.0 0.8 0.0 HOH
 2.803
 NH1
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 ARG A:137 A:351 188.0 0.836 E -121.2 130.4 188.0 0.836 0.0 HOH
 2.572
 NH1
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 ARG A:137 A:351 187.0 0.831 E -119.0 128.2 187.0 0.831 0.0 HOH
 2.479
 NH1
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 ARG A:137 A:351 172.0 0.764 E -115.0 132.5 4.0 0.018 0.746 B:Q15561:0.747
 PO4
HOH
 2.662
2.853
 NE
NH1
 O4
O
ARG B:137 B:351 172.0 0.764 E -124.7 132.4 21.0 0.093 0.671 A:Q15561:0.671
 PO4
PO4
HOH
 2.752
9.429
3.218
 NH1
NH1
NE
 O1
O2
O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ARG A:136 A:351 179.0 0.796 E -124.5 134.7 179.0 0.796 0.0 PO4
PO4
HOH
 3.004
9.343
3.975
 NH1
NH1
CD
 O4
O3
O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ARG A:136 A:351 178.0 0.791 E -125.4 132.1 178.0 0.791 0.0 HOH
 2.773
 NH1
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 ARG A:137 A:351 186.0 0.827 E -123.6 130.9 186.0 0.827 0.0 SO4
HOH
 2.910
3.947
 NH1
CD
 O4
O
ARG B:137 B:351 184.0 0.818 E -123.6 125.3 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 ARG A:137 A:351 156.0 0.693 E -112.9 121.0 156.0 0.693 0.0
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 ARG A:139 A:344 72.0 0.32 E -89.6 141.9 46.0 0.204 0.116 C:Q80V24:0.116
 HOH
 3.316
 CA
 O
ARG B:139 B:344 71.0 NA E -92.7 144.5 71.0 NA NA
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 ARG A:139 A:344 190.0 0.844 E -118.0 132.6 190.0 0.844 0.0 ACT
HOH
 3.036
4.615
 NH1
N
 CH3
O
ARG C:139 B:344 187.0 0.831 E -123.5 130.7 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 ARG A:138 A:344 117.0 0.52 E -129.3 116.7 117.0 0.52 0.0 HOH
 2.061
 HH11
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 ARG A:137 A:344 157.0 0.698 E -128.6 136.3 157.0 0.698 0.0 HOH
 2.629
 NE
 O
ARG C:137 C:344 186.0 0.827 E -125.6 145.2 NA NA NA
ARG E:137 E:344 186.0 0.827 E -117.5 137.6 NA NA NA
ARG G:137 G:344 179.0 0.796 -155.7 115.7 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 ARG A:137 A:344 181.0 0.804 E -123.8 132.2 181.0 0.804 0.0 HOH
 4.875
 N
 O
ARG B:137 B:344 177.0 0.787 E -117.4 133.5 177.0 0.787 0.0 HOH
 3.185
 NH1
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 ARG A:142 A:344 182.0 0.809 E -137.1 135.6 182.0 0.809 0.0
ARG B:142 B:344 171.0 0.76 E -123.5 136.3 NA NA NA
ARG C:142 C:344 188.0 0.836 E -128.4 134.1 NA NA NA
ARG D:142 D:344 178.0 0.791 E -127.6 129.1 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 ARG C:144 A:344 50.0 NA E -127.4 124.6 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 ARG D:146 B:344 172.0 0.764 E -127.5 124.7 172.0 0.764 0.0 HOH
 9.515
 NH1
 O
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 ARG A:147 A:343 159.0 0.707 E -127.8 129.3 159.0 0.707 0.0
ARG B:147 B:343 198.0 0.88 E -124.7 114.6 NA NA NA
ARG C:147 C:343 166.0 0.738 E -126.0 131.3 NA NA NA
ARG D:147 D:343 173.0 0.769 E -128.4 119.2 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 ARG A:137 A:328 49.0 NA E -114.9 138.9 49.0 NA NA HOH
 5.315
 N
 O
ARG B:137 B:328 40.0 NA E -112.4 132.2 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 ARG A:136 A:328 175.0 0.778 E -139.3 133.7 175.0 0.778 0.0 HOH
 2.968
 NH2
 O
ARG C:136 D:328 173.0 0.769 E -117.2 128.1 NA NA NA
ARG E:136 B:328 157.0 0.698 E -120.0 135.9 NA NA NA
ARG G:136 C:328 167.0 0.742 E -122.4 122.5 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 ARG A:136 A:328 169.0 0.751 E -121.6 129.9 169.0 0.751 0.0
ARG C:136 C:328 173.0 0.769 E -143.1 110.0 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 ARG A:150 A:343 171.0 0.76 E -118.3 134.1 171.0 0.76 0.0 HOH
 3.832
 CD
 O
ARG B:150 B:343 165.0 0.733 E -130.2 131.2 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 ARG A:139 A:343 172.0 0.764 E -117.5 131.1 172.0 0.764 0.0 HOH
 2.189
 NE
 O
ARG B:139 B:343 155.0 0.689 E -128.4 129.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 ARG A:351 A:351 169.0 0.751 E -117.2 129.6