Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3149322 . G A CCDS31729.1:NM_003213.3:c.1088cGg>cAg_NP_003204.2:p.363R>Q Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 ARG A:148 A:363 79.0 0.351 E 50.0 48.0 79.0 0.351 0.0 MYR
HOH
 9.414
2.718
 C
O
 O2
O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 ARG A:148 A:363 75.0 0.333 E 52.0 48.9 75.0 0.333 0.0 HOH
 2.659
 O
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:148 A:363 78.0 0.347 E 49.1 49.2 78.0 0.347 0.0 HOH
 2.769
 O
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:148 A:363 77.0 0.342 E 49.7 47.4 77.0 0.342 0.0 HOH
 3.106
 NH1
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 ARG A:148 A:363 84.0 0.373 E 49.9 43.0 84.0 0.373 0.0 HOH
 3.217
 NH1
 O
ARG C:148 B:363 85.0 0.378 E 52.9 51.6 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 ARG A:148 A:363 73.0 0.324 E 52.3 50.1 73.0 0.324 0.0 PO4
HOH
 9.955
2.963
 N
NH1
 O2
O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ARG A:148 A:363 74.0 0.329 E 54.6 44.8 74.0 0.329 0.0 HOH
 3.633
 NH1
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 ARG A:148 A:363 78.0 0.347 E 54.2 48.8 78.0 0.347 0.0 MYR
HOH
 9.873
2.642
 C
O
 O1
O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 ARG A:149 A:363 78.0 0.347 E 48.7 48.5 78.0 0.347 0.0 HOH
 3.429
 CZ
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 ARG A:149 A:363 79.0 0.351 E 46.2 51.1 79.0 0.351 0.0 MYR
HOH
 9.886
3.247
 C
NH1
 O1
O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 ARG A:149 A:363 75.0 0.333 E 50.1 48.2 74.0 0.329 0.004 B:Q15561:0.004
 PO4
PO4
PO4
HOH
 9.612
4.257
3.611
3.523
 N
CG
NH1
C
 O1
O1
O1
O
ARG B:149 B:363 76.0 0.338 E 47.2 48.8 75.0 0.333 0.005 A:Q15561:0.004
 PO4
PO4
PO4
HOH
 7.554
5.312
3.292
3.687
 N
CD
NH1
NH1
 O3
O4
O3
O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ARG A:148 A:363 79.0 0.351 E 52.6 47.9 79.0 0.351 0.0 PO4
PO4
HOH
 3.946
3.619
3.029
 CG
CD
NH1
 O1
O1
O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 ARG A:148 A:363 75.0 0.333 E 53.8 47.8 75.0 0.333 0.0 MYR
HOH
 9.492
2.792
 C
NH1
 C3
O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 ARG A:149 A:363 83.0 0.369 E 49.8 51.6 83.0 0.369 0.0 HOH
 2.728
 O
 O
ARG B:149 B:363 80.0 0.356 E 50.7 54.1 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 ARG A:149 A:363 71.0 0.316 E 52.8 52.9 71.0 0.316 0.0 HOH
 4.284
 NH2
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 ARG A:151 A:356 95.0 0.422 E 46.2 48.9 95.0 0.422 0.0
ARG B:151 B:356 87.0 0.387 E 47.5 43.9 87.0 0.387 0.0
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 ARG A:151 A:356 102.0 0.453 E 35.4 55.9 102.0 0.453 0.0 HOH
 4.326
 N
 O
ARG C:151 B:356 42.0 NA S 53.0 16.4 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 ARG A:150 A:356 71.0 0.316 E 54.1 44.6 71.0 0.316 0.0 HOH
 2.181
 HH11
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 ARG A:149 A:356 96.0 0.427 E 16.7 54.2 96.0 0.427 0.0 HOH
 5.242
 N
 O
ARG C:149 C:356 87.0 0.387 S -64.0 81.4 NA NA NA
ARG E:149 E:356 94.0 0.418 E 58.8 46.1 NA NA NA
ARG G:149 G:356 153.0 0.68 S -151.5 151.8 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 ARG A:149 A:356 81.0 0.36 E 50.8 47.7 81.0 0.36 0.0 HOH
 4.139
 NH1
 O
ARG B:149 B:356 87.0 0.387 E 50.5 47.4 87.0 0.387 0.0 HOH
 5.648
 N
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 ARG A:154 A:356 96.0 0.427 E 52.8 47.8 96.0 0.427 0.0
ARG B:154 B:356 105.0 0.467 E -140.5 54.5 NA NA NA
ARG C:154 C:356 91.0 0.404 E 56.1 42.3 NA NA NA
ARG D:154 D:356 104.0 0.462 E -136.4 63.8 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 ARG C:156 A:356 82.0 0.364 E 54.3 50.1 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 ARG D:158 B:356 86.0 0.382 E 31.2 59.9 86.0 0.382 0.0 HOH
 5.046
 CG
 O
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 ARG A:159 A:355 101.0 0.449 E 56.2 57.1 101.0 0.449 0.0 KK9
HOH
 8.772
7.819
 C
C
 O2
O
ARG B:159 B:355 99.0 0.44 E 57.5 55.3 NA NA NA
ARG C:159 C:355 100.0 0.444 E 56.4 57.5 NA NA NA
ARG D:159 D:355 100.0 0.444 E 62.5 54.8 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 ARG A:149 A:340 104.0 0.462 E 45.1 44.1 104.0 0.462 0.0 HOH
 5.957
 N
 O
ARG B:149 B:340 99.0 0.44 E 42.7 43.1 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 ARG A:148 A:340 92.0 0.409 E 48.6 52.5 92.0 0.409 0.0 MYR
HOH
 9.313
6.697
 C
N
 C3
O
ARG C:148 D:340 96.0 0.427 E 55.9 42.2 NA NA NA
ARG E:148 B:340 88.0 0.391 E 51.9 53.2 NA NA NA
ARG G:148 C:340 94.0 0.418 E 51.0 45.4 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 ARG A:148 A:340 91.0 0.404 E 53.4 57.6 91.0 0.404 0.0 HOH
 4.295
 NH2
 O
ARG C:148 C:340 103.0 0.458 E 47.4 57.2 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 ARG A:162 A:355 93.0 0.413 E 54.4 51.7 93.0 0.413 0.0 HOH
 2.707
 O
 O
ARG B:162 B:355 104.0 0.462 E 54.0 51.8 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 ARG A:151 A:355 106.0 0.471 E 51.4 53.0 106.0 0.471 0.0 Y2D
HOH
 9.362
2.808
 C
O
 H7
O
ARG B:151 B:355 105.0 0.467 E 57.8 49.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 ARG A:363 A:363 89.0 0.396 E 46.8 43.8